Article ; Online: Impact of Cardiac Magnetic Resonance to Arrhythmic Risk Stratification in Nonischemic Cardiomyopathy.
Cardiac electrophysiology clinics
2023 Volume 15, Issue 3, Page(s) 379–390
Abstract: Left ventricular ejection fraction-based arrhythmic risk stratification in nonischemic cardiomyopathy (NICM) is insufficient and has led to the failure of primary prevention implantable cardioverter defibrillator trials, mainly due to the inability of ... ...
Abstract | Left ventricular ejection fraction-based arrhythmic risk stratification in nonischemic cardiomyopathy (NICM) is insufficient and has led to the failure of primary prevention implantable cardioverter defibrillator trials, mainly due to the inability of selecting patients at high risk for sudden cardiac death (SCD). Cardiac magnetic resonance offers unique opportunities for tissue characterization and has gained a central role in arrhythmic risk stratification in NICM. The presence of myocardial scar, denoted by late gadolinium enhancement, is a significant, independent, and strong predictor of ventricular arrhythmias and SCD with high negative predictive value. T1 maps and extracellular volume fraction, which are able to quantify diffuse fibrosis, hold promise as complementary tools but need confirmatory results from large studies. |
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MeSH term(s) | Humans ; Stroke Volume ; Ventricular Function, Left ; Contrast Media ; Risk Factors ; Gadolinium ; Cardiomyopathies/diagnostic imaging ; Death, Sudden, Cardiac/prevention & control ; Defibrillators, Implantable ; Magnetic Resonance Spectroscopy ; Risk Assessment ; Magnetic Resonance Imaging, Cine |
Chemical Substances | Contrast Media ; Gadolinium (AU0V1LM3JT) |
Language | English |
Publishing date | 2023-05-27 |
Publishing country | United States |
Document type | Journal Article ; Review |
ISSN | 1877-9190 |
ISSN (online) | 1877-9190 |
DOI | 10.1016/j.ccep.2023.04.009 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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