Article: Size and Number of Gastric Varices Decide Amount of Glue Injected during Endoscopic Therapy.
The Journal of the Association of Physicians of India
2023 Volume 71, Issue 1, Page(s) 1
Abstract: Introduction: Cyanoacrylate glue injection has become standard of care for acutely bleeding as well as for primary and secondary prophylaxis of high risk gastric varices. There is limited data on safe and effective amount of glue injected. Our study was ...
| Abstract | Introduction: Cyanoacrylate glue injection has become standard of care for acutely bleeding as well as for primary and secondary prophylaxis of high risk gastric varices. There is limited data on safe and effective amount of glue injected. Our study was aimed to fulfill the gap. Materials: It was retrospective analysis of endoscopy laboratory chart, videos and corresponding case sheets of all consecutive endoscopies January to September 2022. Number, type and size of gastric varices, amount of glue injected and outcomes (technical success, intra procedural and post-procedural complications) were noted. Result: Among 337 upper gastrointestinal endoscopies performed during the study period, 12 patients had gastric varices. 3 had GOV1F1, 2 had GOV1F2, 8 had GOV2F2, 1 had GOV2F3 and one had isolated gastric varices, IGV2F1. 4 patients had history of upper GI bleed. 3 had one, 4 had two and 3 had three varices. 3 patients had <0.5 cm and 8 had >0.5 cm size varices. Cyanoacrylate glue was injected in 4 patients. Technical success was achieved in all (100%) patients. The amount of Cyanoacrylate glue injected was decided by the size and number of varices and varied between 1-4 ml depending on the above factors. Two patients had intra-procedural, self subsiding bleeding, one patient had severe abdominal pain needing intramuscular analgesic. None had fatal complication. Conclusion: Size and numbers of gastric varices are deciding factors for amount of glue injected during endotherapy. References Kumar A, Singh S, Madan K, et al. Undiluted N-butyl cyanoacrylate is safe and effective for gastric variceal bleeding. Gastrointest Endosc 2010;72(4):721-727. Saraswat VA, Verma A. Gluing gastric varices in 2012: lessons learnt over 25 years. J Clin Exp Hepatol 2012;2(1):55-69. |
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| MeSH term(s) | Humans ; Esophageal and Gastric Varices/therapy ; Esophageal and Gastric Varices/complications ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/therapy ; Retrospective Studies ; Cyanoacrylates/therapeutic use ; Endoscopy, Gastrointestinal/adverse effects ; Varicose Veins/complications ; Treatment Outcome |
| Chemical Substances | Cyanoacrylates |
| Language | English |
| Publishing date | 2023-03-31 |
| Publishing country | India |
| Document type | Journal Article |
| ZDB-ID | 800766-4 |
| ISSN | 0004-5772 |
| ISSN | 0004-5772 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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