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  1. AU="Annarita, Santoro"
  2. AU="Fluerant, Marshall"
  3. AU="Di Marino, Luca"
  4. AU="Lu, Zonghong"
  5. AU="Saz-Leal, Paula"
  6. AU="Caillier, Stacy J"
  7. AU="Curran, Kathryn G"
  8. AU=Wu Jun
  9. AU="Singhal, Jyotsana"
  10. AU="Fossa, Paola"
  11. AU="Hu, Chung-Chi"
  12. AU="Azad, Rashid"
  13. AU="Bumcrot, David"
  14. AU="Jun, Yu Kyung"
  15. AU="Ganapathy, Kalaiselvan"
  16. AU=Laue Thomas
  17. AU="Yanlan Wang"

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  1. Artikel ; Online: Surgical Treatment of a Late Post-Coarctation Aortic Aneurysm.

    Annarita, Santoro / Germano, Melissano

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2022  

    Sprache Englisch
    Erscheinungsdatum 2022-10-07
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2022.10.015
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: The Prognostic Role of ST2L and sST2 in Patients Who Underwent Carotid Plaque Endarterectomy

    Pietro Scicchitano / Andrea Marzullo / Annarita Santoro / Annapaola Zito / Francesca Cortese / Cristina Galeandro / Andrea Sebastiano Ciccone / Domenico Angiletta / Fabio Manca / Raffaele Pulli / Eliano Pio Navarese / Paul A. Gurbel / Marco Matteo Ciccone

    Journal of Clinical Medicine, Vol 11, Iss 3142, p

    A Five-Year Follow-Up Study

    2022  Band 3142

    Abstract: Soluble suppressor of tumorigenicity (sST)-2 plasma concentration is related to atherosclerosis. The aim of this study was to assess the prognostic impact of sST2 and its membrane-associated form (ST2L) in patients with carotid atherosclerotic plaque who ...

    Abstract Soluble suppressor of tumorigenicity (sST)-2 plasma concentration is related to atherosclerosis. The aim of this study was to assess the prognostic impact of sST2 and its membrane-associated form (ST2L) in patients with carotid atherosclerotic plaque who underwent endarterectomy (CEA). Eighty-two consecutive patients (age range: 48–86 years) who underwent CEA were enrolled. Anthropometric, clinical, instrumental, and laboratory evaluations were gathered. Thirty-seven (45%) patients were symptomatic of cerebrovascular diseases. Patients underwent a five-year follow-up. Phone calls and the analysis of national and regional databases were performed in order to evaluate the occurrence of the primary outcome (all-cause mortality). The population was divided according to survival status. Statins were administered in 81% and 87.5% of survivors and non-survivors, respectively. sST2 levels were higher in non-survivors than in survivors (117.0 ± 103.9 vs. 38.0 ± 30.0 ng/mL, p < 0.001) and in symptomatic individuals, compared with asymptomatic (80.3 ± 92.1 ng/mL vs. 45.4 ± 41.4 ng/mL, p = 0.02). ROC curve analysis identified sST2 cut-off: >98.44 ng/mL as the best predictor for mortality. At the one-year follow-up, the survival rate decreased up to 20% in patients with sST2 higher than the cut-off value. A multivariate regression analysis revealed that only sST2 (HR: 1.012, 95% CI: 1.008–1.016, p < 0.0001) and triglycerides plasma levels (HR: 1.008, 95% CI: 1.002–1.015, p = 0.0135) remained significantly associated with all-cause mortality. ST2L was not associated with all-cause mortality risk. sST2 may act as an independent prognostic determinant of all-cause mortality and symptomatic cerebrovascular diseases in patients with carotid atherosclerotic plaque who underwent CEA.
    Schlagwörter sST2 ; ST2L ; carotid plaque ; atherosclerosis ; biomarkers ; prognosis ; Medicine ; R
    Thema/Rubrik (Code) 610 ; 616
    Sprache Englisch
    Erscheinungsdatum 2022-05-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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