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  1. Article ; Online: Carotid artery stenting has similar outcomes in men and women.

    Ansuategui, Marina / Ibarra, Gabriela / Romero, Carmen / Comanges, Alejandra / Gonzalez-Fajardo, Jose A

    Jornal vascular brasileiro

    2021  Volume 20, Page(s) e20200169

    Abstract: Background: The aim of carotid interventions is to prevent cerebrovascular events. Endovascular treatment (carotid-artery-stenting/CAS) has become established as an alternative to open surgery in some cases. Historically, female sex has been considered ... ...

    Abstract Background: The aim of carotid interventions is to prevent cerebrovascular events. Endovascular treatment (carotid-artery-stenting/CAS) has become established as an alternative to open surgery in some cases. Historically, female sex has been considered as a perioperative risk factor, however, there are few studies regarding this hypothesis when it comes to CAS.
    Objectives: To analyze the CAS results in our center adjusted by sex.
    Methods: A retrospective cohort study was designed, including patients with carotid atheromatosis operated at a single center from January 2016 to June 2019. Our objective was to compare cardiovascular risk, including myocardial infarction, stroke, and mortality, by sex. Follow-up rates of stent patency, restenosis, stroke, myocardial infarction, and death were reported.
    Results: 71 interventions were performed in 50 men (70.42%) and 21 women (29.57%). Mean age was 70.50 ± 10.72 years for men and 73.62 ± 11.78 years for women. Cardiovascular risk factors did not differ significantly between sexes. Mean follow-up was 11.28 ± 11.28 months. There were no significant differences in neurological events during follow-up. No adverse cardiological events were detected at any time. Regarding the mortality rate, during medium-term follow up there were 2 neurological related deaths with no significant differences between sexes (p=0.8432). Neither sex had higher rated of restenosis during long term follow-up (5.63%
    Conclusions: Despite the limitations of our study, CAS is a therapeutic option that is as effective and safe in women as in men. No sex differences were observed.
    Language English
    Publishing date 2021-05-31
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2571403-X
    ISSN 1677-7301 ; 1677-7301
    ISSN (online) 1677-7301
    ISSN 1677-7301
    DOI 10.1590/1677-5449.200169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Oncological outcome of wide anatomic resection with partial mesorectal excision in patients with upper and middle rectal cancer.

    Jiménez-Toscano, Marta / Montcusí, Blanca / Ansuátegui, Marina / Alonso, Sandra / Salvans, Silvia / Pascual, Marta / Pera, Miguel

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2021  Volume 23, Issue 7, Page(s) 1837–1847

    Abstract: Aim: The aim was to investigate the influence of distal resection margin and extent of mesorectal excision on long-term oncological outcomes.: Method: Consecutive patients with upper and middle third rectal cancer from June 2006 to February 2016 were ...

    Abstract Aim: The aim was to investigate the influence of distal resection margin and extent of mesorectal excision on long-term oncological outcomes.
    Method: Consecutive patients with upper and middle third rectal cancer from June 2006 to February 2016 were reviewed. Patients were divided into four groups depending on the distal margin considered as a surrogate marker of the extension of mesorectal excision (Q1 ≤10 mm, Q2 11-20 mm, Q3 21-30 mm, Q4 ≥31 mm). Local-recurrence-free survival (LRFS), disease-free survival (DFS) and overall survival (OS) were estimated. Cox regression models were used to investigate the influence of surgical and clinicopathological variables on prognosis by adjusting for confounding factors.
    Results: Two hundred and eleven patients with mid (125) and upper (86) rectal cancer underwent wide mesorectal excision. The median follow-up was 48.64 months (interquartile range 28-63). 17.5% patients developed recurrence. The 5-year LRFS, DFS and OS for all patients were 93.20%, 83.89% and 80.1%, respectively, with no statistically significant differences between groups (LRFS, P = 0.601; DFS, P = 0.487; OS, P = 0.468). In the multivariable analysis the recurrences and survival were associated with the quality of the mesorectum (LRFS, hazard ratio 10.629, 95% CI 2.324-48.610, P = 0.002; DFS, hazard ratio 2.789, 95% CI 1.314-5.922, P = 0.008).
    Conclusion: A wide anatomical resection with partial mesorectal excision and shorter distal resection margin does not jeopardize the oncological outcomes.
    MeSH term(s) Disease-Free Survival ; Humans ; Mesocolon ; Neoplasm Recurrence, Local ; Prognosis ; Rectal Neoplasms/surgery ; Rectum/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15690
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Atrial Fibrillation and Surgical Patients with Peripheral Arterial Disease.

    González-Fajardo, José A / Ansuategui, Marina / Romero, Carmen / Comanges, Alejandra / Cases, Cristina / Gómez-Arbeláez, Diego

    Annals of vascular surgery

    2020  Volume 67, Page(s) 411–416

    Abstract: Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice and its prevalence rate significantly increases with age. The prognostic implication of AF in surgical patients with peripheral arterial disease (PAD) has ... ...

    Abstract Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice and its prevalence rate significantly increases with age. The prognostic implication of AF in surgical patients with peripheral arterial disease (PAD) has not been analyzed. The aims of this study were to analyze the prevalence of AF among patients operated on with symptomatic PAD, and to determine whether these patients are at a higher risk of death or amputation.
    Methods: We designed a retrospective cohort study, from January 2013 to December 2017, in which we analyzed the medical records of all consecutive patients with symptomatic PAD admitted to our hospital and underwent a vascular procedure. We compared the outcomes of patients with and without AF. All statistically significant demographic variables that underwent a univariate analysis were inserted in the stepwise multivariate model along with AF. A survival analysis was performed to evaluate the factors associated with mortality through a Cox regression model. P-value of 0.05 was considered statistically significant.
    Results: Four hundred three patients were admitted in-hospital with symptomatic PAD and they underwent a vascular intervention. The mean follow-up was 2 years. Seventy-six patients (18.8%) had AF. These patients were older (78 ± 9.1 years) than the 327 patients without AF (68 ± 12.37 years) (P < 0.0001), and more likely to undergo emergency surgery (18.42% vs. 7.34%, P = 0.0029). Age and emergency admission were dependent associates of AF. The patients with AF were frequently men (69.7%) with previous hypertension (96% %). The presence of AF was associated with higher rate of all-cause mortality (55.26%, P < 0.0001, hazard ratio 2.24, confidence interval 1.55-3.25), but the multivariate analysis adjusted for risk factors showed that the mortality was only associated with age because these patients were older and with many comorbidities. The majority of this population with AF showed some tissue lesion when they were admitted in-hospital (Rutherford V-VI, AF 80.2%, P = 0.0004), and this fact justified that a 22.36% underwent a major amputation affecting the ischemic lower limb in admission (P = 0.018). During the follow-up the free amputation rate was similar between groups (60.5% AF vs. 78.3% non-AF).
    Conclusions: This study showed the high prevalence of AF in patients with symptomatic PAD that required surgical admission in-hospital. The presence of AF was related with a greater and serious risk of mortality, but this was independently associated to age, because patients with AF were older and frailer. Clearly, this group of patients had a high risk of amputation when they arrived to the hospital and they needed emergency surgery.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Amputation ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/mortality ; Emergencies ; Female ; Frail Elderly ; Humans ; Limb Salvage ; Male ; Middle Aged ; Patient Admission ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/mortality ; Peripheral Arterial Disease/surgery ; Prevalence ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Spain/epidemiology ; Time Factors ; Treatment Outcome ; Vascular Surgical Procedures/adverse effects ; Vascular Surgical Procedures/mortality
    Language English
    Publishing date 2020-03-21
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2020.02.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2882: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Mortalidad de los pacientes covid-19 con complicaciones trombóticas.

    Gonzalez-Fajardo, José A / Ansuategui, Marina / Romero, Carmen / Comanges, Alejandra / Gómez-Arbeláez, Diego / Ibarra, Gabriela / Garcia-Gutierrez, Ania

    Medicina clinica

    2020  Volume 156, Issue 3, Page(s) 112–117

    Abstract: Objective: To analyze the survival of patients hospitalized with covid-19 and who presented some vascular thrombotic complication.: Material and methods: All consecutive patients with covid-19 who were treated during the months of March and April ... ...

    Title translation Mortality of covid-19 patients with vascular thrombotic complications.
    Abstract Objective: To analyze the survival of patients hospitalized with covid-19 and who presented some vascular thrombotic complication.
    Material and methods: All consecutive patients with covid-19 who were treated during the months of March and April 2020 at our institution were included. All patients were symptomatic and the thrombotic event objectively confirmed. Patients with deep vein thrombosis (DVT), pulmonary embolism (PE), ischemic stroke, and peripheral arterial thrombosis (PAT) were included. Survival curves for all groups were analyzed using Kaplan-Meier with log rank test, and Cox regression.
    Results: During the pandemic period from March-1 to April-30, 2943 patients were treated with confirmed covid-19 in our center. Of them, 106 patients showed some symptomatic vascular thrombosis: 13 patients had PAT, 15 ischemic stroke, 20 DVT and 58 PE. Another 11 patients presented multiple vascular thrombosis. Although the mean age was 65 years, there were differences between groups being older those patients with arterial thrombosis. A 67.92% were men. In total, 25 patients died during their hospital admission (23.58%), with differences between groups, being more common in patients with PAT (9 patients out of 13) and ischemic stroke (8 patients out of 15), than in those with DVT (1 patient out of 20) or PE (7 patients out of 58).
    Conclusions: The venous thromboembolic risk in these patients is greater than the arterial, but arterial thrombosis when it occurs was associated with high mortality rates. Survival was better in patients with DVT and PE than in patients with ischemic stroke or PAT.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/mortality ; Female ; Hospital Mortality ; Hospitalization ; Humans ; Male ; Middle Aged ; Pulmonary Embolism/mortality ; Pulmonary Embolism/virology ; Risk Factors ; Spain/epidemiology ; Stroke/mortality ; Stroke/virology ; Survival Analysis ; Thrombosis/mortality ; Thrombosis/virology
    Language Spanish
    Publishing date 2020-11-06
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.10.004
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.279: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Mortality of COVID-19 patients with vascular thrombotic complications.

    Gonzalez-Fajardo, José A / Ansuategui, Marina / Romero, Carmen / Comanges, Alejandra / Gómez-Arbeláez, Diego / Ibarra, Gabriela / Garcia-Gutierrez, Ania

    Medicina clinica (English ed.)

    2020  Volume 156, Issue 3, Page(s) 112–117

    Abstract: Purpose: To analyze the survival of patients hospitalized with COVID-19 and who presented some vascular thrombotic complication.: Material and methods: All consecutive patients with COVID-19 who were treated during the months of March and April 2020 ... ...

    Abstract Purpose: To analyze the survival of patients hospitalized with COVID-19 and who presented some vascular thrombotic complication.
    Material and methods: All consecutive patients with COVID-19 who were treated during the months of March and April 2020 at our institution were included. All patients were symptomatic and the thrombotic event objectively confirmed. Patients with deep vein thrombosis (DVT), pulmonary embolism (PE), ischemic stroke, and peripheral arterial thrombosis (PAT) were included. Survival curves for all groups were analyzed using Kaplan-Meier with Log Rank test, and Cox regression.
    Results: During the pandemic period from March-1 to April-30, 2943 patients were treated with confirmed COVID-19 in our center. 106 patients showed some symptomatic vascular thrombosis: 13 patients had PAT, 15 ischemic stroke, 20 DVT and 58 PE. 11 patients presented multiple vascular thrombosis. Although the mean age was 65 years, there were differences between groups being older those patients with arterial thrombosis. A 67.92% were men. In total, 25 patients died during their hospital admission (23.58%), with differences between groups, being more common in patients with PAT (9 patients out of 13) and ischemic stroke (8 patients out of 15), than in those with DVT (1 patient out of 20) or PE (7 patients out of 58).
    Conclusions: The venous thromboembolic risk in these patients is greater than the arterial, but arterial thrombosis when it occurs was associated with high mortality rates. Survival was better in patients with DVT and PE than in patients with ischemic stroke or PAT.
    Language English
    Publishing date 2020-12-30
    Publishing country Spain
    Document type Journal Article
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: MORTALIDAD DE LOS PACIENTES COVID-19 CON COMPLICACIONES TROMBÓTICAS VASCULARES

    Gonzalez-fajardo, José A. / Ansuategui, Marina / Romero, Carmen / Comanges, Alejandra / Gómez-Arbeláez, Diego / Ibarra, Gabriela / Garcia-Gutierrez, Ania

    Medicina Clínica ; ISSN 0025-7753

    2020  

    Keywords General Medicine ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.medcli.2020.10.004
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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