Article ; Online: PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma
Nature Communications, Vol 10, Iss 1, Pp 1-
2019 Volume 10
Abstract: Transcription factors are critical regulators of cell identity. Here, the authors use computational and functional genomic approaches to show an oncogenic role of PAX8 in renal cancer. Mechanistic dissection of PAX8 functions reveal its role in ... ...
| Abstract | Transcription factors are critical regulators of cell identity. Here, the authors use computational and functional genomic approaches to show an oncogenic role of PAX8 in renal cancer. Mechanistic dissection of PAX8 functions reveal its role in activating genes associated with metabolic pathways. |
|---|---|
| Keywords | Science ; Q |
| Language | English |
| Publishing date | 2019-08-01T00:00:00Z |
| Publisher | Nature Publishing Group |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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