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Article ; Online: Enhanced Recovery After Surgery Patients Are Prescribed Fewer Opioids at Discharge: A Propensity-score Matched Analysis.

Maurer, Lydia R / El Moheb, Mohamad / Cavallo, Elena / Antonelli, Donna M / Linov, Pamela / Bird, Sarah / Faulkner, Heather R / Del Carmen, Marcela / Qadan, Motaz / Ferrone, Cristina R / Kaafarani, Haytham M A / Sisodia, Rachel / Ellis, Dan B

Annals of surgery

2023 Volume 277, Issue 2, Page(s) e287–e293

Abstract: Objective: We aimed to compare discharge opioid prescriptions pre- and post-ERAS implementation.: Summary of background data: ERAS programs decrease inpatient opioid use, but their relationship with postdischarge opioids remains unclear.: Methods: ...

Abstract	Objective: We aimed to compare discharge opioid prescriptions pre- and post-ERAS implementation. Summary of background data: ERAS programs decrease inpatient opioid use, but their relationship with postdischarge opioids remains unclear. Methods: All patients undergoing hysterectomy between October 2016 and November 2020 and pancreatectomy or hepatectomy between April 2017 and November 2020 at 1 tertiary care center were included. For each procedure, ERAS was implemented during the study period. PSM was performed to compare pre - versus post-ERAS patients on discharge opioids (number of pills and oral morphine equivalents). Patients were matched on age, sex, race, payor, American Society of Anesthesiologists score, prior opioid use, and procedure. Sensitivity analyses in open versus minimally invasive surgery cohorts were performed. Results: A total of 3983 patients were included (1929 pre-ERAS; 2054 post-ERAS). Post-ERAS patients were younger (56.0 vs 58.4 years; P < 0.001), more often female (95.8% vs 78.1%; P < 0.001), less often white (77.2% vs 82.0%; P < 0.001), less often had prior opioid use (20.1% vs 28.1%; P < 0.001), and more often underwent hysterectomy (91.1% vs 55.7%; P < 0.001). After PSM, there were no significant differences between cohorts in baseline characteristics. Matched post-ERAS patients were prescribed fewer opioid pills (17.4 pills vs 22.0 pills; P < 0.001) and lower oral morphine equivalents (129.4 mg vs 167.6 mg; P < 0.001) than pre-ERAS patients. Sensitivity analyses confirmed these findings [open (18.8 pills vs 25.4 pills; P < 0.001 \ 138.9 mg vs 198.7 mg; P < 0.001); minimally invasive surgery (17.2 pills vs 21.1 pills; P < 0.001 \ 127.1 mg vs 160.1 mg; P < 0.001). Conclusions: Post-ERAS patients were prescribed significantly fewer opioids at discharge compared to matched pre-ERAS patients.
MeSH term(s)	Humans ; Female ; Analgesics, Opioid/therapeutic use ; Patient Discharge ; Enhanced Recovery After Surgery ; Aftercare ; Pain, Postoperative/drug therapy ; Opioid-Related Disorders ; Morphine Derivatives
Chemical Substances	Analgesics, Opioid ; Morphine Derivatives
Language	English
Publishing date	2023-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	340-2
ISSN	1528-1140 ; 0003-4932
ISSN (online)	1528-1140
ISSN	0003-4932
DOI	10.1097/SLA.0000000000005042
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Article ; Online: Intraoperative Deaths: Who, Why, and Can We Prevent Them?

Dorken Gallastegi, Ander / Mikdad, Sarah / Kapoen, Carolijn / Breen, Kerry A / Naar, Leon / Gaitanidis, Apostolos / El Hechi, Majed / Pian-Smith, May / Cooper, Jeffrey B / Antonelli, Donna M / MacKenzie, Olivia / Del Carmen, Marcela G / Lillemoe, Keith D / Kaafarani, Haytham M A

The Journal of surgical research

2022 Volume 274, Page(s) 185–195

Abstract: Introduction: Intraoperative deaths (IODs) are rare but catastrophic. We systematically analyzed IODs to identify clinical and patient safety patterns.: Methods: IODs in a large academic center between 2015 and 2019 were included. Perioperative ... ...

Abstract	Introduction: Intraoperative deaths (IODs) are rare but catastrophic. We systematically analyzed IODs to identify clinical and patient safety patterns. Methods: IODs in a large academic center between 2015 and 2019 were included. Perioperative details were systematically reviewed, focusing on (1) identifying phenotypes of IOD, (2) describing emerging themes immediately preceding cardiac arrest, and (3) suggesting interventions to mitigate IOD in each phenotype. Results: Forty-one patients were included. Three IOD phenotypes were identified: trauma (T), nontrauma emergency (NT), and elective (EL) surgery patients, each with 2 sub-phenotypes (e.g., ELm and ELv for elective surgery with medical arrests or vascular injury and bleeding, respectively). In phenotype T, cardiopulmonary resuscitation was initiated before incision in 42%, resuscitative thoracotomy was performed in 33%, and transient return of spontaneous circulation was achieved in 30% of patients. In phenotype NT, ruptured aortic aneurysms accounted for half the cases, and median blood product utilization was 2,694 mL. In phenotype ELm, preoperative evaluation did not include electrocardiogram in 12%, cardiac consultation in 62%, stress test in 87%, and chest x-ray in 37% of patients. In phenotype ELv, 83% had a single peripheral intravenous line, and vascular injury was almost always followed by escalation in monitoring (e.g., central/arterial line), alert to the blood bank, and call for surgical backup. Conclusions: We have created a framework for IOD that can help with intraoperative safety and quality analysis. Focusing on interventions that address appropriateness versus futility in care in phenotypes T and NT, and on prevention and mitigation of intraoperative vessel injury (e.g., intraoperative rescue team) or preoperative optimization in phenotype EL may help prevent IODs.
MeSH term(s)	Cardiopulmonary Resuscitation ; Heart Arrest/etiology ; Heart Arrest/prevention & control ; Hemorrhage ; Humans ; Thoracotomy ; Vascular System Injuries
Language	English
Publishing date	2022-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2022.01.007
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Article ; Online: Providing a medical home: the cost of care coordination services in a community-based, general pediatric practice.

Antonelli, Richard C / Antonelli, Donna M

Pediatrics

2004 Volume 113, Issue 5 Suppl, Page(s) 1522–1528

Abstract: Objective: To determine the cost of unreimbursable care coordination services for children with special health care needs (CSHCN) in 1 community-based, general pediatric practice.: Methods: A measurement tool was developed to quantify the precise ... ...

Abstract	Objective: To determine the cost of unreimbursable care coordination services for children with special health care needs (CSHCN) in 1 community-based, general pediatric practice. Methods: A measurement tool was developed to quantify the precise activities involved in providing comprehensive, coordinated care for CSHCN. Costs of providing this care were calculated on the basis of time spent multiplied by the average salary of the office personnel performing the care coordination service. In addition, data were collected regarding the complexity level of the patient requiring the service, the type of service provided, and the outcome. Results: During the 95-day study period, 774 encounters that led to care coordination activities were logged, representing service provision to 444 separate patients. When these encounters were examined on the basis of clinical complexity of the patient, the most complex patients constituted 11% of the population of CSHCN yet accounted for 25% of the encounters. In addition, care coordination activities for these clinically complex CSHCN engaged office staff 4 times as long when compared with less clinically complex CSHCN. Overall, 51% of the encounters were attributable to coordinating care for problems not considered typically medical and included activities such as processing referrals with managed care organizations, consulting with schools or other educational programs, and providing oversight for psychosocial issues. On the basis of national salary and benefits data, the annual cost of the time spent coordinating care for CSHCN in this medical home model ranged from 22,809 dollars to 33,048 dollars (representing the 25th and 75th percentiles, respectively). Conclusions: The costs of providing care coordination services to CSHCN in a medical home are appreciable but not prohibitive. Standardization of care coordination practices is essential because it makes the medical home more amenable to quality improvement interventions. Mechanisms to finance unreimbursable care coordination activities must be developed to achieve the Healthy People 2010 objective that all CSHCN have access to a medical home.
MeSH term(s)	Child ; Child Health Services/economics ; Comprehensive Health Care/economics ; Data Collection ; Disabled Children ; Health Care Costs/statistics & numerical data ; Humans ; Massachusetts ; Pediatrics/economics
Language	English
Publishing date	2004-05
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
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Article ; Online: Understanding Our Own Biases as Surgeons: A Departmental Effort.

Rickert, Charles G / Perez, Numa P / Westfal, Maggie L / Antonelli, Donna / Moonsamy, Philicia / Albutt, Katherine / Rosenthal, Martin / Lillemoe, Keith D / Tabrizi, Maryam B

Annals of surgery

2019 Volume 271, Issue 1, Page(s) 39–40

MeSH term(s)	Attitude of Health Personnel ; Humans ; Job Satisfaction ; Quality of Health Care/standards ; Self Concept ; Surgeons/standards
Language	English
Publishing date	2019-07-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	340-2
ISSN	1528-1140 ; 0003-4932
ISSN (online)	1528-1140
ISSN	0003-4932
DOI	10.1097/SLA.0000000000003392
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Article ; Online: Care coordination for children and youth with special health care needs: a descriptive, multisite study of activities, personnel costs, and outcomes.

Antonelli, Richard C / Stille, Christopher J / Antonelli, Donna M

Pediatrics

2008 Volume 122, Issue 1, Page(s) e209–16

Abstract: Objectives: Objectives included testing use of the care-coordination measurement tool in pediatric primary care practices; describing care-coordination activities for children and youth that occur in primary care practices; assessing the relationship of ...

Abstract	Objectives: Objectives included testing use of the care-coordination measurement tool in pediatric primary care practices; describing care-coordination activities for children and youth that occur in primary care practices; assessing the relationship of care-coordination activities in the medical home with outcomes related to resource use; and measuring the direct personnel costs of care-coordination activities. Methods: Six general pediatric practices were selected, representing a diverse range of sizes, locations, patient demographics, and care-coordination activity model types. The care-coordination measurement tool was used over a period of 8 months in 2003 to record all of the nonreimbursable care-coordination activity encounters performed by any office-based personnel. The tool enabled recording of activities, resources-use outcomes, and time. Cost of personnel performing care-coordination activities was derived by extrapolation from the time spent. Results: Care-coordination activity services were used by patients of all complexity levels. Children and youth with special health care needs with acute-onset, family-based psychosocial problems experienced 14% of the care-coordination activity encounters and used 21% of the care-coordination activities minutes. Children and youth without special health care needs, without complicating family psychosocial problems, received 50% of the encounters and used 36% of the care-coordination activity minutes. The average cost per care-coordination activity encounter varied from $4.39 to $12.86, with an overall mean of $7.78. A principal cost driver seemed to be the percentage of care-coordination activities performed by physicians. Office-based nurses prevented a large majority of emergency department visits and episodic office visits. Conclusions: Care-coordination activity was assessed at the practice level, and the care-coordination measurement tool was used successfully during the operations of typical, pediatric, primary care settings. The presence of acute, family-based social stressors was a significant driver of need for care-coordination activities. A high proportion of dependence on care-coordination performed by physicians led to increased costs. Office-based nurses providing care coordination were responsible for a significant number of episodes of avoidance of higher cost use outcomes.
MeSH term(s)	Allied Health Personnel/economics ; Child ; Child, Exceptional ; Disabled Children ; Health Services Needs and Demand/economics ; Health Services Needs and Demand/organization & administration ; Humans ; Patient Care Planning/economics ; Patient Care Planning/organization & administration ; Pediatrics/organization & administration ; Primary Health Care/economics ; Primary Health Care/organization & administration ; United States
Language	English
Publishing date	2008-07
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
DOI	10.1542/peds.2007-2254
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Article ; Online: Description and Impact of a Comprehensive Multispecialty Multidisciplinary Intervention to Decrease Opioid Prescribing in Surgery.

Kaafarani, Haytham M A / Eid, Ahmed I / Antonelli, Donna M / Chang, David C / Elsharkawy, Ahmed E / Elahad, Joana Abed / Lancaster, Elizabeth A / Schulz, John T / Melnitchouk, Serguei I / Kastrinakis, William V / Hutter, Matthew M / Masiakos, Peter T / Colwell, Amy S / Wright, Cameron D / Lillemoe, Keith D

Annals of surgery

2019 Volume 270, Issue 3, Page(s) 452–462

Abstract: Introduction: Diversion of excess prescription opioids contributes to the opioid epidemic. We sought to describe and study the impact of a comprehensive departmental initiative to decrease opioid prescribing in surgery.: Methods: A multispecialty ... ...

Abstract	Introduction: Diversion of excess prescription opioids contributes to the opioid epidemic. We sought to describe and study the impact of a comprehensive departmental initiative to decrease opioid prescribing in surgery. Methods: A multispecialty multidisciplinary initiative was designed to change the culture of postoperative opioid prescribing, including: consensus-built opioid guidelines for 42 procedures from 11 specialties, provider-focused posters displayed in all surgical units, patient opioid/pain brochures setting expectations, and educational seminars to residents, advanced practice providers, residents and nurses. Pre- (April 2016-March 2017) versu post-initiative (April 2017-May 2018) analyses of opioid prescribing at discharge [median oral morphine equivalent (OME)] were performed at the specialty, prescriber, patient, and procedure levels. Refill prescriptions within 3 months were also studied. Results: A total of 23,298 patients were included (11,983 pre-; 11,315 post-initiative). Post-initiative, the median OME significantly decreased for 10 specialties (all P values < 0.001), the percentage of patients discharged without opioids increased from 35.7% to 52.5% (P < 0.001), and there was no change in opioids refills (0.07% vs 0.08%, P = 0.9). Similar significant decreases in OME were observed when the analyses were performed at the provider and individual procedure levels. Patient-level analyses showed that the preinitiative race/sex disparities in opioid-prescribing disappeared post-initiative. Conclusion: We describe a comprehensive multi-specialty intervention that successfully reduced prescribed opioids without increase in refills and decreased sex/race prescription disparities.
MeSH term(s)	Adult ; Analgesics, Opioid/adverse effects ; Analgesics, Opioid/therapeutic use ; Drug Prescriptions/statistics & numerical data ; Drug Utilization Review ; Female ; Humans ; Inappropriate Prescribing/prevention & control ; Interdisciplinary Communication ; Interprofessional Relations ; Male ; Middle Aged ; Needs Assessment ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/prevention & control ; Pain Measurement ; Pain, Postoperative/diagnosis ; Pain, Postoperative/drug therapy ; Patient Compliance/statistics & numerical data ; Practice Guidelines as Topic ; Practice Patterns, Physicians'/standards ; Practice Patterns, Physicians'/trends ; Statistics, Nonparametric ; United States
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2019-07-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	340-2
ISSN	1528-1140 ; 0003-4932
ISSN (online)	1528-1140
ISSN	0003-4932
DOI	10.1097/SLA.0000000000003462
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Article ; Online: Truth in Reporting: How Data Capture Methods Obfuscate Actual Surgical Site Infection Rates within a Health Care Network System.

Bordeianou, Liliana / Cauley, Christy E / Antonelli, Donna / Bird, Sarah / Rattner, David / Hutter, Matthew / Mahmood, Sadiqa / Schnipper, Deborah / Rubin, Marc / Bleday, Ronald / Kenney, Pardon / Berger, David

Diseases of the colon and rectum

2017 Volume 60, Issue 1, Page(s) 96–106

Abstract: Background: Two systems measure surgical site infection rates following colorectal surgeries: the American College of Surgeons National Surgical Quality Improvement Program and the Centers for Disease Control and Prevention National Healthcare Safety ... ...

Abstract	Background: Two systems measure surgical site infection rates following colorectal surgeries: the American College of Surgeons National Surgical Quality Improvement Program and the Centers for Disease Control and Prevention National Healthcare Safety Network. The Centers for Medicare & Medicaid Services pay-for-performance initiatives use National Healthcare Safety Network data for hospital comparisons. Objective: This study aimed to compare database concordance. Design: This is a multi-institution cohort study of systemwide Colorectal Surgery Collaborative. The National Surgical Quality Improvement Program requires rigorous, standardized data capture techniques; National Healthcare Safety Network allows 5 data capture techniques. Standardized surgical site infection rates were compared between databases. The Cohen κ-coefficient was calculated. Setting: This study was conducted at Boston-area hospitals. Patients: National Healthcare Safety Network or National Surgical Quality Improvement Program patients undergoing colorectal surgery were included. Main outcome measures: Standardized surgical site infection rates were the primary outcomes of interest. Results: Thirty-day surgical site infection rates of 3547 (National Surgical Quality Improvement Program) vs 5179 (National Healthcare Safety Network) colorectal procedures (2012-2014). Discrepancies appeared: National Surgical Quality Improvement Program database of hospital 1 (N = 1480 patients) routinely found surgical site infection rates of approximately 10%, routinely deemed rate "exemplary" or "as expected" (100%). National Healthcare Safety Network data from the same hospital and time period (N = 1881) revealed a similar overall surgical site infection rate (10%), but standardized rates were deemed "worse than national average" 80% of the time. Overall, hospitals using less rigorous capture methods had improved surgical site infection rates for National Healthcare Safety Network compared with standardized National Surgical Quality Improvement Program reports. The correlation coefficient between standardized infection rates was 0.03 (p = 0.88). During 25 site-time period observations, National Surgical Quality Improvement Program and National Healthcare Safety Network data matched for 52% of observations (13/25). κ = 0.10 (95% CI, -0.1366 to 0.3402; p = 0.403), indicating poor agreement. Limitations: This study investigated hospitals located in the Northeastern United States only. Conclusions: Variation in Centers for Medicare & Medicaid Services-mandated National Healthcare Safety Network infection surveillance methodology leads to unreliable results, which is apparent when these results are compared with standardized data. High-quality data would improve care quality and compare outcomes among institutions.
MeSH term(s)	Centers for Disease Control and Prevention (U.S.) ; Centers for Medicare and Medicaid Services (U.S.) ; Colectomy ; Colostomy ; Data Accuracy ; Data Collection ; Databases, Factual ; Digestive System Surgical Procedures ; Humans ; Ileostomy ; Laparoscopy ; Quality Improvement ; Reimbursement, Incentive ; Societies, Medical ; Surgical Wound Infection/epidemiology ; United States
Language	English
Publishing date	2017-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1097/DCR.0000000000000715
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Article ; Online: Derivation and validation of a novel severity classification for intraoperative adverse events.

Kaafarani, Haytham M A / Mavros, Michael N / Hwabejire, John / Fagenholz, Peter / Yeh, Daniel D / Demoya, Marc / King, David R / Alam, Hasan B / Chang, Yuchiao / Hutter, Matthew / Antonelli, Donna / Gervasini, Alice / Velmahos, George C

Journal of the American College of Surgeons

2014 Volume 218, Issue 6, Page(s) 1120–1128

Abstract: Background: There is currently no systematic approach to evaluating the severity of intraoperative adverse events (iAEs).: Study design: A 3-phase project was designed to develop and validate a novel severity classification scheme for iAEs. Phase 1 ... ...

Abstract	Background: There is currently no systematic approach to evaluating the severity of intraoperative adverse events (iAEs). Study design: A 3-phase project was designed to develop and validate a novel severity classification scheme for iAEs. Phase 1 created the severity classification using a modified Delphi process. Phase 2 measured the classification's internal consistency by calculating inter-rater reliability among 91 surgeons using standardized iAEs scenarios. Phase 3 measured the classification's construct validity by testing whether major iAEs (severity class ≥3) correlated with worse 30-day postoperative outcomes compared with minor iAEs (severity class <3). This was achieved by creating a matched database using American College of Surgeons NSQIP and administrative data, querying for iAEs using the Patient Safety Indicator #15 (Accidental Puncture/Laceration), and iAE confirmation by chart review. Results: Phase 1 resulted in a 6-point severity classification scheme. Phase 2 revealed an inter-rater reliability of 0.882. Of 9,292 patients, phase 3 included 181 confirmed with iAEs. All preoperative/intraoperative variables, including demographics, comorbidities, type of surgery performed, and operative length, were similar between patients with minor (n = 110) vs major iAEs (n = 71). In multivariable logistic analysis, severe iAEs correlated with higher risks of any postoperative complication (odds ratio [OR] = 3.8; 95% CI, 1.9-7.4; p < 0.001), surgical site infections (OR = 3.7; 95% CI, 1.7-8.2; p = 0.001), systemic sepsis (OR = 6.0; 95% CI, 2.1-17.2; p = 0.001), failure to wean off the ventilator (OR = 3.2; 95% CI, 1.2-8.9; p = 0.022), and postoperative length of stay ≥7 days (OR = 3.0; 95% CI, 1.5-5.9; p = 0.002). Thirty-day mortalities were similar (4.5% vs 7.1%; p = 0.46). Conclusions: We propose a novel iAE severity classification system with high internal consistency and solid construct validity. Our classification scheme might prove essential for benchmarking quality of intraoperative care across hospitals and/or individual surgeons.
MeSH term(s)	Aged ; Female ; Humans ; Intraoperative Complications/classification ; Male ; Middle Aged ; Severity of Illness Index
Language	English
Publishing date	2014-06
Publishing country	United States
Document type	Journal Article ; Validation Studies
ZDB-ID	1181115-8
ISSN	1879-1190 ; 1072-7515
ISSN (online)	1879-1190
ISSN	1072-7515
DOI	10.1016/j.jamcollsurg.2013.12.060
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Article ; Online: Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study.

Kamboj, Mini / Childers, Teresa / Sugalski, Jessica / Antonelli, Donna / Bingener-Casey, Juliane / Cannon, Jamie / Cluff, Karie / Davis, Kimberly A / Dellinger, E Patchen / Dowdy, Sean C / Duncan, Kim / Fedderson, Julie / Glasgow, Robert / Hall, Bruce / Hirsch, Marilyn / Hutter, Matthew / Kimbro, Lisa / Kuvshinoff, Boris / Makary, Martin /

Morris, Melanie / Nehring, Sharon / Ramamoorthy, Sonia / Scott, Rebekah / Sovel, Mindy / Strong, Vivian / Webster, Ashley / Wick, Elizabeth / Aguilar, Julio Garcia / Carlson, Robert / Sepkowitz, Kent

Infection control and hospital epidemiology

2018 Volume 39, Issue 5, Page(s) 555–562

Abstract: BACKGROUNDSurgical site infections (SSIs) following colorectal surgery (CRS) are among the most common healthcare-associated infections (HAIs). Reduction in colorectal SSI rates is an important goal for surgical quality improvement.OBJECTIVETo examine ... ...

Abstract	BACKGROUNDSurgical site infections (SSIs) following colorectal surgery (CRS) are among the most common healthcare-associated infections (HAIs). Reduction in colorectal SSI rates is an important goal for surgical quality improvement.OBJECTIVETo examine rates of SSI in patients with and without cancer and to identify potential predictors of SSI risk following CRSDESIGNAmerican College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) data files for 2011-2013 from a sample of 12 National Comprehensive Cancer Network (NCCN) member institutions were combined. Pooled SSI rates for colorectal procedures were calculated and risk was evaluated. The independent importance of potential risk factors was assessed using logistic regression.SETTINGMulticenter studyPARTICIPANTSOf 22 invited NCCN centers, 11 participated (50%). Colorectal procedures were selected by principal procedure current procedural technology (CPT) code. Cancer was defined by International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes.MAIN OUTCOMEThe primary outcome of interest was 30-day SSI rate.RESULTSA total of 652 SSIs (11.06%) were reported among 5,893 CRSs. Risk of SSI was similar for patients with and without cancer. Among CRS patients with underlying cancer, disseminated cancer (SSI rate, 17.5%; odds ratio [OR], 1.66; 95% confidence interval [CI], 1.23-2.26; P=.001), ASA score ≥3 (OR, 1.41; 95% CI, 1.09-1.83; P=.001), chronic obstructive pulmonary disease (COPD; OR, 1.6; 95% CI, 1.06-2.53; P=.02), and longer duration of procedure were associated with development of SSI.CONCLUSIONSPatients with disseminated cancer are at a higher risk for developing SSI. ASA score >3, COPD, and longer duration of surgery predict SSI risk. Disseminated cancer should be further evaluated by the Centers for Disease Control and Prevention (CDC) in generating risk-adjusted outcomes.Infect Control Hosp Epidemiol 2018;39:555-562.
MeSH term(s)	Adult ; Aged ; Cohort Studies ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/surgery ; Databases, Factual ; Digestive System Surgical Procedures/adverse effects ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Rectum/surgery ; Risk Factors ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; United States/epidemiology
Language	English
Publishing date	2018-03-19
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1017/ice.2018.40
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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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