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  1. Article ; Online: Application of immersive virtual reality mirror therapy for upper limb rehabilitation after stroke: a scoping review.

    Gebreheat, Gdiom / Antonopoulos, Nick / Porter-Armstrong, Alison

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2024  

    Abstract: Mirror therapy is a commonly used rehabilitation intervention in post stroke upper limb rehabilitation. Despite many potential technological developments, mirror therapy is routinely delivered through the use of a static mirror or mirror box. This review ...

    Abstract Mirror therapy is a commonly used rehabilitation intervention in post stroke upper limb rehabilitation. Despite many potential technological developments, mirror therapy is routinely delivered through the use of a static mirror or mirror box. This review aims to synthesise evidence on the application of immersive virtual reality mirror therapy (IVRMT) in poststroke upper limb rehabilitation. A scoping review was performed on relevant English studies published between 2013 to 2023. Literature search was undertaken on APA PsycInfo, CINAHL, Cochrane Library, MEDLINE, PubMed and Web of Science between August 5 and 17, 2023. Additional studies were included from Google Scholar and reference lists of identified articles. A total of 224 records were identified, of which 8 full-text articles were selected for review. All included studies were published between 2019 and 2023, and from high- and upper-middle-income nations. All the studies were experimental (n = 8). The total sample size in the studies was 259, most of whom were stroke patients with upper limb weakness (n = 184). This review identified three major themes and two sub-themes based on the contents of the studies conducted on the application of IVRMT: IVRMT's technical application, feasibility and impact on clinical outcomes (motor recovery and adverse events). IVRMT was concluded to be a safe and feasible approach to post-stroke upper limb rehabilitation, offering enhanced engagement and motor recovery. However, more methodologically robust studies should be conducted to advance this area of practice, and to include a uniform IVRMT intervention protocol, dose, and use of outcome measure.
    Language English
    Publishing date 2024-04-29
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-024-07543-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: DENVIS: Scalable and High-Throughput Virtual Screening Using Graph Neural Networks with Atomic and Surface Protein Pocket Features.

    Krasoulis, Agamemnon / Antonopoulos, Nick / Pitsikalis, Vassilis / Theodorakis, Stavros

    Journal of chemical information and modeling

    2022  Volume 62, Issue 19, Page(s) 4642–4659

    Abstract: Computational methods for virtual screening can dramatically accelerate early-stage drug discovery by identifying potential hits for a specified target. Docking algorithms traditionally use physics-based simulations to address this challenge by ... ...

    Abstract Computational methods for virtual screening can dramatically accelerate early-stage drug discovery by identifying potential hits for a specified target. Docking algorithms traditionally use physics-based simulations to address this challenge by estimating the binding orientation of a query protein-ligand pair and a corresponding binding affinity score. Over the recent years, classical and modern machine learning architectures have shown potential for outperforming traditional docking algorithms. Nevertheless, most learning-based algorithms still rely on the availability of the protein-ligand complex binding pose, typically estimated via docking simulations, which leads to a severe slowdown of the overall virtual screening process. A family of algorithms processing target information at the amino acid sequence level avoid this requirement, however, at the cost of processing protein data at a higher representation level. We introduce deep neural virtual screening (DENVIS), an end-to-end pipeline for virtual screening using graph neural networks (GNNs). By performing experiments on two benchmark databases, we show that our method performs competitively to several docking-based, machine learning-based, and hybrid docking/machine learning-based algorithms. By avoiding the intermediate docking step, DENVIS exhibits several orders of magnitude faster screening times (i.e., higher throughput) than both docking-based and hybrid models. When compared to an amino acid sequence-based machine learning model with comparable screening times, DENVIS achieves dramatically better performance. Some key elements of our approach include protein pocket modeling using a combination of atomic and surface features, the use of model ensembles, and data augmentation via artificial negative sampling during model training. In summary, DENVIS achieves competitive to state-of-the-art virtual screening performance, while offering the potential to scale to billions of molecules using minimal computational resources.
    MeSH term(s) Algorithms ; High-Throughput Screening Assays ; Ligands ; Machine Learning ; Membrane Proteins ; Molecular Docking Simulation ; Neural Networks, Computer ; Protein Binding
    Chemical Substances Ligands ; Membrane Proteins
    Language English
    Publishing date 2022-09-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 190019-5
    ISSN 1549-960X ; 0095-2338
    ISSN (online) 1549-960X
    ISSN 0095-2338
    DOI 10.1021/acs.jcim.2c01057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1230: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book ; Conference proceedings: AP2PS 2012

    Antonopoulos, Nick

    the Fourth International Conference on Advances in P2P Systems, September 23 - 28, 2012, Barcelona, Spain ; [held at NexTech 2012]

    2012  

    Institution International Academy, Research, and Industry Association
    Event/congress AP2PS (4, 2012.09.23-28, BarcelonaSpain) ; International Conference on Advances in P2P Systems (4, 2012.09.23-28, BarcelonaSpain) ; NexTech (2012.09.23-28, BarcelonaSpain)
    Author's details IARIA. Ed.: Nick Antonopoulos
    Language English
    Size 36 S., Ill., graph. Darst.
    Publisher Curran
    Publishing place Red Hook, NY
    Document type Book ; Conference proceedings
    Note Literaturangaben
    ISBN 9781622763979 ; 1622763971
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book: Handbook of research on P2P and grid systems for service-oriented computing

    Antonopoulos, Nick

    : models, methodologies and applications

    2010  

    Author's details Nick Antonopoulos ... [et al.]
    Language English
    Size XXXVII, 588 S., 44 S, Ill., graph. Darst
    Publisher Information Science Reference
    Publishing place Hershey, Pa. u.a.
    Document type Book
    Note Literaturangaben
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book: Handbook of research on P2P and grid systems for service-oriented computing

    Antonopoulos, Nick

    : models, methodologies and applications

    2010  

    Author's details Nick Antonopoulos ... [et al.]
    Language English
    Size XXXVII, S. 589 - 1178, 44 S, Ill., graph. Darst
    Publisher Information Science Reference
    Publishing place Hershey, Pa. u.a.
    Document type Book
    Note Literaturangaben
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book ; Online: Cloud Computing

    Antonopoulos, Nick

    Principles, Systems and Applications

    (Computer Communications and Networks)

    2010  

    Author's details edited by Nick Antonopoulos, Lee Gillam
    Series title Computer Communications and Networks
    Keywords Computer science ; Computer system performance ; Operating systems (Computers)
    Language English
    Size Online-Ressource, v.: digital
    Publisher Springer-Verlag London Limited
    Publishing place London
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 9781849962407 ; 9781849962414 ; 1849962405 ; 1849962413
    DOI 10.1007/978-1-84996-241-4
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Online: Handbook of research on P2P and grid systems for service-oriented computing

    Antonopoulos, Nick

    models, methodologies and applications

    2010  

    Abstract: 1. A survey of peer-to-peer architectures for service oriented computing / Danny Hughes, Geof Coulson, James Walkerdine -- 2. Taxonomy of grid systems / Heba Kurdi, Maozhen Li, H. Al-Raweshidy -- 3. Peer-to-peer search techniques for service-oriented ... ...

    Institution IGI Global
    Author's details [edited by] Nick Antonopoulos ... [et al.]
    Abstract 1. A survey of peer-to-peer architectures for service oriented computing / Danny Hughes, Geof Coulson, James Walkerdine -- 2. Taxonomy of grid systems / Heba Kurdi, Maozhen Li, H. Al-Raweshidy -- 3. Peer-to-peer search techniques for service-oriented computing / Lu Liu, Duncan Russell, Jie Xu -- 4. A survey of efficient resource discovery techniques on DHTs / Carlos Abalde, Víctor Gulías, Javier París -- 5. Semantic technologies for distributed search P2P networks / Amitava Biswas, Suneil Mohan, Rabi Mahapatra -- 6. Grid, P2P and SOA orchestration / Tran Pham, Lydia Lau, Peter Dew -- 7. Service-oriented architectures for pervasive computing / Elias Manolakos, Demetris Galatopoullos -- 8. Overview of service oriented architecture for resource management in P2P systems / Farag Azzedin, Mohamed Eltoweissy, Salman Khwaja -- 9. Managing the future internet / Carlos Kamienski, Ramide Dantas, Djamel Sadok, Börje Ohlman -- 10. P2P network management / Chunsheng Ni, Jilong Wang -- 11. Business grids, infrastructuring the future of ICT / Carmelo Ragusa -- 12. Peer-to-peer service discovery for grid computing / Eddy Caron, Frédéric Desprez, Franck Petit, Cédric Tedeschi -- 13. Survey on grid computing on mobile consumer devices / Jochen Furthmüller, Oliver Waldhorst -- 14. P2P in scalable cross-layer control planes of next generation networks / Moisés Ribeiro, Marconi Fardin, Helio Waldman -- 15. Distributed indexing networks for efficient large-scale group communication / George Popescu --

    16. Adaptive query processing in data grids / Chunjiang Zhao, Junwei Cao, Huarui Wu, Weiwei Chen -- 17. Distributed and adaptive service discovery using preference / Ryota Egashira, Akihiro Enomoto, Tatsuya Suda -- 18. Cooperation incentives / Mohammed Hawa -- 19. Exploiting P2P and grid computing technologies for resource sharing to support high performance distributed system / Liangxiu Han -- 20. Resource co-allocation in grid computing environments / Marco Netto, Rajkumar Buyya -- 21. Self-adjustment for service provisioning in grids / Daniel Batista, Nelson da Fonseca -- 22. Improving energy-efficiency of computational grids via scheduling / Ziliang Zong, Xiaojun Ruan, Adam Manzanares, Kiranmai Bellam, Xiao Qin -- 23. Dynamic overlay networks for robust and scalable routing / Bart De Vleeschauwer, Filip De Turck, Bart Dhoedt, Piet Demeester -- 24. A fault tolerant decentralized scheduling in large scale distributed systems / Florin Pop -- 25. Data replication in P2P systems / Vassilios Dimakopoulos, Spiridoula Margariti, Mirto Ntetsika, Evaggelia Pitoura -- 26. Maintaining redundancy in peer-to-peer storage systems / Anwitaman Datta, Di Wu, Liu Xin, Adam Wierzbicki -- 27. Making scientific applications on the grid reliable through flexibility approaches borrowed from service compositions / Dimka Karastoyanova, Frank Leymann -- 28. A general framework for the modeling and simulation of grid and P2P systems / Ciprian Dobre --

    29. Grid service level agreements using financial risk analysis techniques / Bin Li, Lee Gillam -- 30. Virtual hierarchical tree grid organizations (VIRGO) / Lican Huang -- 31. Electronic business contracts between services / Simon Miles, Nir Oren, Michael Luck, Sanjay Modgil, Felipe Meneguzzi, Nora Faci, Camden Holt, Gary Vickers -- 32. Trust and fairness management in P2P and grid systems / Adam Wierzbicki, Tomasz Kaszuba, Radoslaw Nielek -- 33. Trust calculation and management in P2P and grid systems / Karaoglanoglou Konstantinos, Helen Karatza -- 34. Taking trust management to the next level / Rehab Alnemr, Matthias Quasthoff, Christoph Meinel -- 35. Designing grid security infrastructures using identity-based cryptography / Hoon Lim -- 36. Enforcing fairness in asynchronous collaborative environments / Guillaume Pierre, Steen van -- 37. Service providers indexing using P2P systems / G. Marchetto, M. Manzillo, L. Torrero, L. Ciminiera, F. Risso -- 38. SIP protocol for supporting grid computing / Aldo Campi, Franco Callegati -- 39. Agent-based infrastructure for dynamic composition of grid services / Matthew Adigun, Johnson Iyilade, Klaas Kabini -- 40. Exploiting P2P solutions in telecommunication service delivery platforms / Antonio Manzalini, Roberto Minerva, Corrado Moiso -- 41. Fednets / Malohat Ibrohimovna, Sonia Heemstra de Groot -- 42. Overlay-based middleware for the pervasive grid / Paul Grace, Danny Hughes, Geoff Coulson, Gordon Blair, Barry Porter, Francois Taiani -- 43. Digital ecosystems / A. Razavi, P. Krause, S. Moschoyiannis -- 44. Providing VoD services in community networks using P2P technology / Juan Muñoz-Gea, Josemaria Malgosa-Sanahuja, Pedro Piñero-Escuer, Joan García-Haro -- 45. Service-oriented symbolic computations / Dana Petcu, Georgiana Macariu, Alexandru Cârstea, Marc Frîncu -- 46. Applications of wireless sensor networks / Corinna Schmitt, Georg Carle

    This book addresses the need for peer-to-peer computing and grid paradigms in delivering efficient service-oriented computing. This collection of research facilitates a broad understanding of the subject matter useful to researchers and doctoral students working specifically in the deployment, implementation, and study of related topics including distributed computing, software engineering, Web services, and modeling of business processes--Provided by publisher
    Keywords Computational grids (Computer systems) ; Peer-to-peer architecture (Computer networks) ; Service oriented architecture ; Web services
    Language English
    Size 1 Online-Ressource (electronic texts (894 p.)), digital files
    Publisher IGI Global (701 E. Chocolate Avenue, Hershey, Pennsylvania, 17033, USA)
    Publishing place Hershey, Pa
    Document type Book ; Online
    Note IMD-Felder maschinell generiert ; Includes bibliographical references and index ; Restricted to subscribers or individual electronic text purchasers
    ISBN 9781615206865 ; 9781615206872 ; 1615206868 ; 1615206876
    Database ECONomics Information System

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  8. Book ; Online: Cloud Computing

    Antonopoulos, Nick

    Principles, Systems and Applications

    (Computer Communications and Networks)

    2010  

    Author's details edited by Nick Antonopoulos, Lee Gillam
    Series title Computer Communications and Networks
    Keywords Computer science ; Computer system performance ; Operating systems (Computers)
    Language English
    Size Online-Ressource, v.: digital
    Publisher Springer-Verlag London Limited
    Publishing place London
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 9781849962407 ; 9781849962414 ; 1849962405 ; 1849962413
    DOI 10.1007/978-1-84996-241-4
    Database Former special subject collection: coastal and deep sea fishing

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book: Handbook of research on P2P and grid systems for service-oriented computing

    Antonopoulos, Nick

    models, methodologies and applications

    2009  

    Abstract: This book addresses the need for peer-to-peer computing and grid paradigms in delivering efficient service-oriented computing"--Provided by ... ...

    Author's details Nick Antonopoulos ... [et al.]
    Abstract "This book addresses the need for peer-to-peer computing and grid paradigms in delivering efficient service-oriented computing"--Provided by publisher
    Keywords Computational grids (Computer systems) ; Peer-to-peer architecture (Computer networks) ; Service oriented architecture ; Web services
    Language English
    Publisher Information Science Reference
    Publishing place Hershey, Pa. u.a.
    Document type Book
    ISBN 9781615206865 ; 9781615206872 ; 1615206868 ; 1615206876
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book: Cloud computing

    Antonopoulos, Nick / Gillam, Lee

    principles, systems and applications

    (Computer communications and networks)

    2010  

    Abstract: Cloud computing has recently emerged as a subject of substantial industrial & academic interest, though its meaning & scope is hotly debated. This book provides comprehensive coverage of the state-of-the-art in cloud computing, highlighting & clarifying ... ...

    Author's details Nick Antonopoulos; Lee Gillam, eds
    Series title Computer communications and networks
    Abstract Cloud computing has recently emerged as a subject of substantial industrial & academic interest, though its meaning & scope is hotly debated. This book provides comprehensive coverage of the state-of-the-art in cloud computing, highlighting & clarifying the conceptual & systemic links with other distributed computing approaches
    Keywords Cloud computing
    Language English
    Size XVII, 379 S., Ill., graph. Darst., Kt., 235 mm x 155 mm
    Publisher Springer
    Publishing place London u.a.
    Document type Book
    Note Hier auch später erschienene, unveränderte Nachdrucke ; Literaturangaben
    ISBN 9781447125808 ; 9781849962407 ; 9781849962414 ; 1447125800 ; 1849962405 ; 1849962413
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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