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  1. Article: Vliyanie fakoemul'sifikatsii vozrastnoi katarakty na uroven' oftal'motonusa i parametry iridokorneal'nogo ugla pri pervichnoi otkrytougol'noi glaukome.

    Antonov, A A / Khderi, Kh / Bersunkayev, M K / Pateyuk, L S

    Vestnik oftalmologii

    2024  Volume 139, Issue 6, Page(s) 60–68

    Abstract: Cataract phacoemulsification with intraocular lens implantation significantly affects the morphology of the anterior chamber angle (ACA) and contributes to a reduction of intraocular pressure (IOP).: Purpose: This study investigates the changes in ... ...

    Title translation The effect of phacoemulsification of age-related cataract on intraocular pressure and iridocorneal angle parameters in primary open-angle glaucoma.
    Abstract Cataract phacoemulsification with intraocular lens implantation significantly affects the morphology of the anterior chamber angle (ACA) and contributes to a reduction of intraocular pressure (IOP).
    Purpose: This study investigates the changes in anterior chamber angle configuration and IOP level before and after cataract surgery in primary open-angle glaucoma (POAG) eyes, and assesses its possible relationship with the axial length of the eye.
    Material and methods: The study included 38 patients with immature senile cataract and compensated unoperated stage I-II POAG. Patients underwent anterior segment optical coherence tomography (AS-OCT) with measurement of the angle opening distance (AOD
    Results: After the surgery 92.11% of patients showed a decrease in IOP
    Conclusions: Cataract extraction contributes to a significant reduction in IOP due to anterior chamber angle expansion, trabecular meshwork stretching, and improved aqueous outflow.
    MeSH term(s) Humans ; Intraocular Pressure ; Phacoemulsification/adverse effects ; Glaucoma, Open-Angle/complications ; Glaucoma, Open-Angle/diagnosis ; Glaucoma, Open-Angle/surgery ; Lens Implantation, Intraocular/adverse effects ; Anterior Chamber/diagnostic imaging ; Cataract/complications ; Cataract/diagnosis ; Tomography, Optical Coherence/methods ; Glaucoma, Angle-Closure
    Language Russian
    Publishing date 2024-01-18
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202313906160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Vliyanie keratorefraktsionnoi khirurgii na rezul'taty tonometrii po Maklakovu.

    Antonov, A A / Klinicheva, E A / Volzhanin, A V / Makarova, A S

    Vestnik oftalmologii

    2024  Volume 140, Issue 2. Vyp. 2, Page(s) 51–59

    Abstract: Purpose: The study investigates the influence of changes in keratometric parameters after refractive surgery on the results of Maklakov tonometry.: Material and methods: The study examined a total of 61 people (121 eyes). The patients were divided ... ...

    Title translation Effect of refractive surgery on Maklakov tonometry results.
    Abstract Purpose: The study investigates the influence of changes in keratometric parameters after refractive surgery on the results of Maklakov tonometry.
    Material and methods: The study examined a total of 61 people (121 eyes). The patients were divided into a control group with no history of surgery (16 people, 31 eyes), a LASIK group (13 people, 26 eyes), a femtosecond-assisted LASIK (FS-LASIK) group (16 people, 32 eyes), and a photorefractive keratectomy (PRK) group (16 people, 32 eyes). The patients underwent standard examination, keratometry (Km), Maklakov tonometry with a 10 g weight, and elastotonometry with 5, 7.5, and 15 g weights.
    Results: In the LASIK group, the indentation diameter with 5 and 7.5 g weights correlated with Km in the central and near-paracentral zone (
    In the control group, there were practically no correlations for 5 and 7.5 g weights. The indentation diameter of the 10 g weight evenly correlated with Km at all points (
    Conclusion: Tonometry readings with the 10 g weight are the most dependent on Km in different groups, and the readings with the 5 g weight are the least dependent. LASIK is characterized by the largest scatter of dependencies for weights of different masses, FS-LASIK - by the smallest. Tonometry readings with the 5 g weight correlated with Km only in the LASIK group, and this was the only direct correlation. Considering the inverse nature of most correlations, higher Km may be associated with an overestimation of tonometry results, and lower Km - with its underestimation.
    MeSH term(s) Humans ; Adult ; Male ; Female ; Tonometry, Ocular/methods ; Photorefractive Keratectomy/methods ; Keratomileusis, Laser In Situ/methods ; Cornea/surgery ; Cornea/diagnostic imaging ; Cornea/physiopathology ; Myopia/surgery ; Myopia/physiopathology ; Myopia/diagnosis ; Intraocular Pressure/physiology
    Language Russian
    Publishing date 2024-04-30
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202414002251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Vliyanie krivizny i perifericheskoi tolshchiny rogovitsy na rezul'tat tonometrii.

    Antonov, A A / Volzhanin, A V / Klinicheva, E A / Karpilova, M A

    Vestnik oftalmologii

    2024  Volume 140, Issue 2. Vyp. 2, Page(s) 43–50

    Abstract: Purpose: This study investigates the influence of peripheral corneal thickness (PCT) and its curvature on tonometry readings.: Material and methods: The study included 49 patients (49 eyes) who were indicated for glaucoma surgery. Using bidirectional ...

    Title translation Influence of corneal curvature and peripheral thickness on tonometry readings.
    Abstract Purpose: This study investigates the influence of peripheral corneal thickness (PCT) and its curvature on tonometry readings.
    Material and methods: The study included 49 patients (49 eyes) who were indicated for glaucoma surgery. Using bidirectional applanation tonometry, the following parameters were obtained: IOPcc, IOPg - intraocular pressure (IOP) corrected for corneal compensation, taken as the most reliable indicator; IOP converted to Goldmann measurement, taken as the result of applanation tonometry, ΔIOP (IOPcc-IOPg), CH and CRF (corneal hysteresis and corneal resistance factor). During corneal topography, the corneal thickness was studied in the center, PCT at 1.5; 2, 3, 4 and 5 mm from the center in four meridians, as well as ΔPCT (PCT 3 mm - PCT 1.5 mm), the curvature of the anterior and posterior surfaces of the cornea and the depth of the anterior chamber. Aberrometry was used to obtain refractometry data and the curvature of the anterior surface of the cornea. The influence of the studied parameters on ΔIOP was evaluated.
    Results: ΔIOP correlated with CRF (
    Conclusion: Biomechanical parameters of the cornea are the leading factor of applanation tonometry error. Individual linear dimensions of the cornea (thickness, curvature) have a lesser effect.
    MeSH term(s) Humans ; Tonometry, Ocular/methods ; Cornea/diagnostic imaging ; Intraocular Pressure/physiology ; Male ; Female ; Middle Aged ; Corneal Topography/methods ; Glaucoma/physiopathology ; Glaucoma/diagnosis ; Reproducibility of Results ; Aged ; Adult
    Language Russian
    Publishing date 2024-04-30
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202414002243
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  4. Article: Koeffitsient biomekhanicheskogo napryazheniya v otsenke stepeni kompensatsii vnutriglaznogo davleniya.

    Antonov, A A / Kozlova, I V

    Vestnik oftalmologii

    2021  Volume 137, Issue 5. Vyp. 2, Page(s) 255–261

    Abstract: Intraocular pressure is the one modifiable factor, which correct assessment and normalization initiates the treatment of glaucoma. The accuracy of its measurement by traditional methods depends on biomechanical properties of the fibrous tunic of the eye, ...

    Title translation Coefficient of biomechanical stress in assessment of the degree of intraocular pressure compensation.
    Abstract Intraocular pressure is the one modifiable factor, which correct assessment and normalization initiates the treatment of glaucoma. The accuracy of its measurement by traditional methods depends on biomechanical properties of the fibrous tunic of the eye, which in modern clinical practice are most successfully studied by the method of bidirectional applanation of the cornea using the Ocular Response Analyzer (ORA). Mathematical integration of the parameters it measures makes it possible to calculate the coefficient of biomechanical stress (K
    Purpose: To determine the range of normal values of the K
    Material and methods: Two consecutive studies on representative clinical material were used to determine the range of normal K
    Results: The cut-off value for K
    Conclusion: The performed clinical and statistical analysis demonstrates high sensitivity and specificity of the biomechanical stress coefficient in the diagnosis and treatment of glaucoma.
    MeSH term(s) Biomechanical Phenomena ; Cornea ; Glaucoma/diagnosis ; Glaucoma/etiology ; Humans ; Intraocular Pressure ; Tonometry, Ocular
    Language Russian
    Publishing date 2021-10-20
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma2021137052255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Rol' potochechnoi svetochuvstvitel'nosti v otsenke progressirovaniya glaukomy.

    Erichev, V P / Vitkov, A A / Antonov, A A / Asinovskova, I I / Poleva, R P

    Vestnik oftalmologii

    2024  Volume 140, Issue 2. Vyp. 2, Page(s) 34–42

    Abstract: Purpose: This study analyzes changes in light sensitivity in each test point of the visual field in patients with different stages of glaucoma.: Material and methods: The data of a prospective analytical case-control study were analyzed. All patients ...

    Title translation Role of point-by-point light sensitivity in the assessment of glaucoma progression.
    Abstract Purpose: This study analyzes changes in light sensitivity in each test point of the visual field in patients with different stages of glaucoma.
    Material and methods: The data of a prospective analytical case-control study were analyzed. All patients underwent assessment of retinal light sensitivity and its variability in 54 points corresponding to the 24-2 program. Mean light sensitivity values were calculated in each point. Intergroup analysis was performed to evaluate changes in light sensitivity in each point.
    Results: The range of light sensitivity decrease in the early glaucoma group compared to the control group was from 1.5 to 3.6 dB. The range of light sensitivity decrease in the moderate glaucoma group compared to the control group was from 2.1 to 11.5 dB, and compared to the early glaucoma group - from -0.9 to 7.9 dB. The most frequent decrease in light sensitivity was detected in the nasal sector and along the horizontal line in the upper half of the visual field. This trend persisted within the central 10 degrees of the visual field. The range of light sensitivity decrease in the advanced glaucoma group compared to the control group was from 14.1 to 28.0 dB, and compared to the early glaucoma group - from 11.35 to 26.08 dB, compared to the moderate glaucoma group - from 9.1 to 23.5 dB. The most frequent and severe decrease in light sensitivity was detected in the paracentral zone in the lower half of the visual field.
    Conclusion: The study analyzed the trends in the development of glaucoma from the early to the advanced stage. The most frequent and severe defect in light sensitivity in cases of verified advanced glaucoma was found in the lower half of the visual field. Points No. 32, 33 and 40 can be indicated as the area of interest in assessing the progression of glaucoma, as they were found to have the most profound changes in light sensitivity as glaucoma progressed.
    MeSH term(s) Humans ; Visual Fields/physiology ; Disease Progression ; Glaucoma/physiopathology ; Glaucoma/diagnosis ; Male ; Female ; Middle Aged ; Visual Field Tests/methods ; Prospective Studies ; Aged ; Case-Control Studies ; Light
    Language Russian
    Publishing date 2024-04-30
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202414002234
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  6. Article: Porogovye znacheniya i variabel'nost' svetochuvstvitel'nosti setchatki v kazhdoi tochke issleduemogo polya zreniya.

    Vitkov, A A / Antonov, A A / Asinovskova, I I / Kozlova, I V / Semenov, E D

    Vestnik oftalmologii

    2024  Volume 140, Issue 2. Vyp. 2, Page(s) 116–122

    Abstract: Purpose: This study assesses the light sensitivity and its variability in each point of the visual field in patients without glaucoma and with different stages of glaucoma.: Material and methods: The data of a prospective analytical case-control ... ...

    Title translation Thresholds and variability of retinal light sensitivity in each point of the examined visual field.
    Abstract Purpose: This study assesses the light sensitivity and its variability in each point of the visual field in patients without glaucoma and with different stages of glaucoma.
    Material and methods: The data of a prospective analytical case-control study involving 500 patients were analyzed. The initial examination of all patients was performed using basic ophthalmological methods, including static perimetry. Retinal light sensitivity and its variability were assessed in 54 points corresponding to the Humphrey 24-2 program. Mean deviation and pattern standard deviation of light sensitivity were calculated for each point.
    Results: The lowest light sensitivity values in patients with moderate glaucoma were found in the periphery of the nasal sector, at point No. 27 - 14.4 dB, and at points No. 24-26 along the horizontal axis from the nasal side - from 17.7 to 22.7 dB. The maximum variability of light sensitivity was found in the nasal sector on both sides of the horizontal line - from 10.7 to 11.5 dB. The average light sensitivity above the horizontal axis in patients with advanced glaucoma was 10.8 dB, which is 2 dB higher than in the lower half of the visual field - 8.8 dB. The highest light sensitivity values were found at points No. 24 - 17.7 dB and No. 31 - 16.78 dB, the lowest - at point No. 32 - 4.5 dB. The average variability values of light sensitivity in the upper half of the visual field were 9.6 dB, which is 1 dB less than in the lower half of the visual field - 10.6 dB.
    Conclusion: According to our data, points No. 32 and No. 40 are of particular interest in the diagnostic plan. In these loci, the highest light sensitivity values were determined in early and moderate glaucoma. However, the values in these points decrease significantly in advanced glaucoma. It can be assumed that changes in light sensitivity in these loci at the early stages of glaucoma may be a predictor of glaucoma progression.
    MeSH term(s) Humans ; Visual Fields/physiology ; Visual Field Tests/methods ; Glaucoma/physiopathology ; Glaucoma/diagnosis ; Middle Aged ; Male ; Female ; Retina/physiopathology ; Prospective Studies ; Adult ; Light ; Aged ; Sensory Thresholds/physiology ; Case-Control Studies ; Reproducibility of Results
    Language Russian
    Publishing date 2024-04-30
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma2024140022116
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  7. Article: Staticheskaya perimetriya v diagnostike glaukomy. Sposoby otsenki progressirovaniya.

    Erichev, V P / Antonov, A A / Vitkov, A A / Grigoryan, L A

    Vestnik oftalmologii

    2023  Volume 139, Issue 5, Page(s) 96–104

    Abstract: There are several ways to assess glaucoma progression using standard automated perimetry. Most often, ophthalmologists evaluate the stability of visual functions manually when comparing several study protocols. The advantages of clinical assessment are ... ...

    Title translation Static automated perimetry in the diagnosis of glaucoma. Assessment of disease progression.
    Abstract There are several ways to assess glaucoma progression using standard automated perimetry. Most often, ophthalmologists evaluate the stability of visual functions manually when comparing several study protocols. The advantages of clinical assessment are ease of implementation and the ability to interpret data from any device. The main disadvantage of this method is its subjectivity. There are many available automated methods for assessing disease progression involving Humphrey Field Analyzer and Octopus perimeters. Event analysis allows determining glaucoma progression at the time of examination, with consideration of the possible physiological fluctuations in light sensitivity. Trend analysis of perimetric indices makes it possible to assess the rate of glaucoma progression and forecast the trend of changes in visual functions over the next five years. All these methods for assessing progression have certain advantages and disadvantages and cannot be considered ideal. Pointwise and cluster trend analysis are more sensitive in early glaucoma and are being actively researched and developed. These methods have great potential, although they are not yet sufficiently available in clinical practice.
    MeSH term(s) Humans ; Visual Field Tests/methods ; Visual Fields ; Glaucoma/diagnosis ; Cluster Analysis ; Disease Progression
    Language Russian
    Publishing date 2023-11-09
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202313905196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Molecular-statistical theory of elasticity in nematic liquid crystals composed of polar and nonpolar molecules.

    Osipov, M A / Antonov, A A / Gorkunov, M V

    Physical review. E

    2021  Volume 103, Issue 5-1, Page(s) 52701

    Abstract: A molecular-statistical theory of the orientational elasticity of nematic liquid crystals has been developed employing the orientational deformation tensor which describes the rotation of the director. An explicit expression for the general elasticity ... ...

    Abstract A molecular-statistical theory of the orientational elasticity of nematic liquid crystals has been developed employing the orientational deformation tensor which describes the rotation of the director. An explicit expression for the general elasticity tensor of the nematic phase has been obtained and the Frank elastic constants are expressed in terms of the three independent parameters of this tensor. Explicit expressions for the Frank elastic constants have been derived in the molecular field approximation in terms of the orientational order parameters and the corresponding coefficients of expansion of the intermolecular potential in spherical invariants. Frank elastic constants have been calculated numerically for nematic liquid crystals composed of both polar and nonpolar molecules together with the orientational order parameters using the classical Gay-Berne model interaction potential and the two of its popular modifications. The polarity of the uniaxial molecular shape has been directly introduced into the model potential by modifying the distance of closest approach. The elastic constants are presented as functions of temperature for different values of the molecular elongation, the anisotropy of the potential well and the molecular shape polarity. It has been shown that the elastic constants are much more sensitive to the details of the intermolecular interaction potential in comparison with the orientational order parameters. In particular, a relatively weak polarity of the molecular shape may result in an unusual decrease of the splay constant K_{11} which may vanish at some temperature leading to the instability of the homogeneous nematic phase. This may represent a mechanism of the formation of the splay-bend phase.
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.103.052701
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  9. Article: Vliyanie polozheniya tela na rezul'taty tochechnoi kontaktnoi tonometrii v tsentre i na periferii rogovitsy.

    Antonov, A A / Vostrukhin, S V / Volzhanin, A V / Vitkov, A A

    Vestnik oftalmologii

    2022  Volume 139, Issue 2, Page(s) 28–34

    Abstract: Purpose: This study analyzes the fluctuations of intraocular pressure (IOP) and clarifies the error of paracentral rebound tonometry associated with change in body position.: Material and methods: The study included 45 healthy volunteers aged 25.4±2 ... ...

    Title translation The effect of body position on the results of central and paracentral rebound tonometry.
    Abstract Purpose: This study analyzes the fluctuations of intraocular pressure (IOP) and clarifies the error of paracentral rebound tonometry associated with change in body position.
    Material and methods: The study included 45 healthy volunteers aged 25.4±2.1 years. First we performed rebound tonometry in the sitting position in the center of the cornea and 3-4 mm from the temporal and nasal sides (Icare-
    Results and discussion: Initial IOPcc and IOPg were 4.6±2.8 and 14.8±2.8 mm Hg. Initial Icare-
    Conclusion: Paracentral rebound tonometry findings exceed those of rebound tonometry in central cornea, but in body position change the alteration of measurements in the same points on the cornea are comparable. In the supine position IOP increases on average by 1.0-1.5 mm Hg compared to the sitting position.
    MeSH term(s) Humans ; Prospective Studies ; Reproducibility of Results ; Intraocular Pressure ; Glaucoma ; Tonometry, Ocular
    Language Russian
    Publishing date 2022-04-24
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202313902128
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  10. Article: Sovremennye vozmozhnosti oftal'motonometrii pri patologicheskikh izmeneniyakh rogovitsy.

    Trufanov, S V / Malozhen, S A / Antonov, A A / Makarova, M A

    Vestnik oftalmologii

    2022  Volume 138, Issue 1, Page(s) 71–77

    Abstract: Changes in intraocular pressure have great influence on the course of various processes in ocular tissues. Presently, the scientific discussion has returned to the theoretical issues of tonometry and the creation of models that would allow assessing the ... ...

    Title translation Modern capabilities of ophthalmic tonometry in pathologically altered corneas.
    Abstract Changes in intraocular pressure have great influence on the course of various processes in ocular tissues. Presently, the scientific discussion has returned to the theoretical issues of tonometry and the creation of models that would allow assessing the influence of various ocular parameters on IOP values. Some of the modern tonometers (Icare, Tono-Pen) are convenient and effective when measuring IOP in eyes with damaged, uneven or edematous cornea. It is necessary to analyze the results of ophthalmic tonometry by modern methods in accordance with the data of direct intracameral manometry in pathological conditions of the cornea and after keratoplasty.
    MeSH term(s) Cornea/pathology ; Cornea/surgery ; Corneal Transplantation ; Humans ; Intraocular Pressure ; Manometry ; Reproducibility of Results ; Tonometry, Ocular
    Language Russian
    Publishing date 2022-03-02
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 962921-x
    ISSN 0042-465X
    ISSN 0042-465X
    DOI 10.17116/oftalma202213801171
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