Article ; Online: Propranolol as an effective therapy for infantile haemangioma of the urinary bladder.
BMJ case reports
2019 Volume 12, Issue 2
Abstract: Infantile haemangiomas are one of the most common tumours in infancy, but typically present as cutaneous lesions; haemangiomas of the urinary bladder are incredibly rare. Although benign, these can sometimes ulcerate and bleed, causing haematuria in the ... ...
Abstract | Infantile haemangiomas are one of the most common tumours in infancy, but typically present as cutaneous lesions; haemangiomas of the urinary bladder are incredibly rare. Although benign, these can sometimes ulcerate and bleed, causing haematuria in the case of bladder lesions. Propranolol is a well-documented medical therapy for cutaneous lesions, but surgical treatment dominates the literature on bladder haemangiomas. We present the case of a child with infantile haemangiomas of the urinary bladder, as well as internal and cutaneous lesions, treated with propranolol. At 6-week follow-up cystoscopy and MRI, there was a significant improvement in both bladder and internal lesions, respectively. Follow-up with dermatology 9 months after initiation of propranolol demonstrated excellent regression of the cutaneous lesions with a marked decrease in both size and prominence. This case demonstrates the potential role of propranolol in the treatment of bladder haemangiomas in lieu of more invasive surgical techniques. |
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MeSH term(s) | Female ; Hemangioma/drug therapy ; Humans ; Infant, Newborn ; Propranolol/therapeutic use ; Treatment Outcome ; Urinary Bladder Neoplasms/drug therapy |
Chemical Substances | Propranolol (9Y8NXQ24VQ) |
Language | English |
Publishing date | 2019-02-01 |
Publishing country | England |
Document type | Case Reports ; Journal Article |
ISSN | 1757-790X |
ISSN (online) | 1757-790X |
DOI | 10.1136/bcr-2018-226929 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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