LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 174

Search options

  1. Article ; Online: Supporting the dying is a community responsibility.

    M Aoun, Samar

    Palliative care and social practice

    2022  Volume 16, Page(s) 26323524221102468

    Language English
    Publishing date 2022-06-16
    Publishing country United States
    Document type Editorial
    ISSN 2632-3524
    ISSN (online) 2632-3524
    DOI 10.1177/26323524221102468
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Conference proceedings: Congress of Neurological Surgeons essential papers in neurosurgery

    Bendok, Bernard R. / El Tecle, Najib E. / El Ahmadieh, Tarek Y. / Aoun, Salah G.

    2021  

    Abstract: The Congress of Neurological Surgeons (CNS) Essential Papers in Neurosurgery brings to the neurosurgical community a unique collection of critically appraised neurosurgical papers shedding light on some of the most impactful studies in the history of ... ...

    Title variant Essential papers in neurosurgery
    Institution American Congress of Neurological Surgeons
    Author's details edited by Najib E. El Tecle, Tarek Y. El Ahmadieh, Salah G. Aoun, Bernard Bendok
    Abstract "The Congress of Neurological Surgeons (CNS) Essential Papers in Neurosurgery brings to the neurosurgical community a unique collection of critically appraised neurosurgical papers shedding light on some of the most impactful studies in the history of neurosurgery. The "CNS Essential Papers" project is rooted in the culture of evidence-based medicine and data-driven decision making"--
    Keywords Neurosurgical Procedures ; Nervous System Diseases / surgery
    Language English
    Size xx, 252 Seiten, Illustrationen
    Publisher Oxford University Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT020808555
    ISBN 978-0-19-753434-2 ; 9780197534366 ; 9780197534373 ; 0-19-753434-1 ; 0197534368 ; 0197534376
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 A 436 available for loan (reading room) Lesesaal EG

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Optical coherence tomography angiography findings in Bergmeister's papilla.

    Ben Aoun, S / Hachicha, I / Bouraoui, R / Limaiem, R / El Matri, L

    Journal francais d'ophtalmologie

    2023  Volume 46, Issue 10, Page(s) 1260–1261

    MeSH term(s) Humans ; Tomography, Optical Coherence ; Optic Disk ; Angiography ; Fluorescein Angiography
    Language English
    Publishing date 2023-08-17
    Publishing country France
    Document type Journal Article
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2023.03.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1417: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: An engineered thermally tolerant apo-cytochrome scaffold for metal-less incorporation of heme derivative.

    Ben Aoun, Sami / Ibrahim, Sheikh Muhammad

    PloS one

    2023  Volume 18, Issue 11, Page(s) e0293972

    Abstract: Cytochrome c552 from Thermus thermophilus is one of the hot topics for creating smart biomaterials as it possesses remarkable stability, is tolerant to multiple mutations and has therefore been recently reported for a number of functionalizations upon ... ...

    Abstract Cytochrome c552 from Thermus thermophilus is one of the hot topics for creating smart biomaterials as it possesses remarkable stability, is tolerant to multiple mutations and has therefore been recently reported for a number of functionalizations upon substitution of the original prosthetic group with an artificial prosthetic group. However, all of the substitutions were driven by the coordination through the axial ligands followed by complete reconstitution with a metal-porphyrin complex. This limits the scope of the cytochrome c for incorporating a metal-less non-natural heme species that could improve the versatility of cytochrome c for a new generation of engineered cytochrome proteins for further enhancement in their functionalities such as biocatalysts. In this connection, a new variant of Cytochrome c (rC552 C14A) from Thermus thermophilus was reported, where an easy approach to remove the original prosthetic group was achieved, followed by the incorporation of a number of metal-PPIX derivatives that ultimately led to the formation of artificial c-type cytochromes through covalent bonding. The apo-cytochrome was found to be thermally tolerant and to possess a distinctive overall structure as that of the wild type, as was evident from the corresponding CD spectra, which ultimately encouraged reconstitution with a metal-less protoporphyrin derivative for better understanding the role of axial ligands in the reconstitution process. Successful reconstitution was achieved, resulting in a new type of Cytochrome b-type artificial protein without the metal in its active site, indicating the non-involvement of the axial ligand. In order to prove the non-involvement of the axial ligand, a subsequent double mutant (C14A/M69A) was constructed, replacing the methionine at 69 position with non-coordinating alanine residue. Accordingly, the apo-C14A/M69A was prepared and found to be extremely stable as the earlier mutants and the WT showed no signs of denaturation, even at the elevated temperature of 98°C. Subsequently, heme b was successfully incorporated into the apo-C14A/M69A, which demonstrated itself as a highly thermally tolerant protein scaffold for incorporating a metal-less artificial prosthetic group in the absence of the axial ligand. Further improvement in the reconstitution process is achieved by replacing the methionine at 69 position with phenyl alanine (C14A/M69F mutant), resulting in further stabilization of heme species, possibly through non-covalent π-interactions, as corroborated by molecular docking.
    MeSH term(s) Cytochromes c/genetics ; Cytochromes c/metabolism ; Heme/metabolism ; Molecular Docking Simulation ; Ligands ; Methionine/metabolism ; Alanine/metabolism ; Oxidation-Reduction
    Chemical Substances Cytochromes c (9007-43-6) ; Heme (42VZT0U6YR) ; Ligands ; Methionine (AE28F7PNPL) ; Alanine (OF5P57N2ZX)
    Language English
    Publishing date 2023-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0293972
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Métastase irienne d’un cancer du sein révélée par un ectropion uvéal.

    Sassi, H / Ouederni, M / Ben Aoun, S / Bouguila, H / Cheour, M

    Journal francais d'ophtalmologie

    2021  Volume 44, Issue 8, Page(s) 1297–1299

    Title translation Breast cancer metastatic to the iris presenting as ectropion uveae.
    MeSH term(s) Breast Neoplasms/diagnosis ; Ectropion/diagnosis ; Ectropion/etiology ; Female ; Humans ; Iris/diagnostic imaging ; Iris Diseases
    Language French
    Publishing date 2021-08-24
    Publishing country France
    Document type Journal Article
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2020.12.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1417: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: In silico selection of an aptamer for the design of aptamer-modified magnetic beads bearing ferrocene co-immobilized label for capacitive detection of acetamiprid.

    Algethami, Faisal K / Rabti, Amal / Mastouri, Mohamed / Ben Aoun, Sami / Abdulkhair, Babiker Y / Raouafi, Noureddine

    Talanta

    2023  Volume 258, Page(s) 124445

    Abstract: In silico evaluation of aptamer/target interactions can facilitate the development of efficient biosensor with high specificity and affinity. In this work, we present in silico, i.e. structural similarity, molecular docking and molecular dynamics ... ...

    Abstract In silico evaluation of aptamer/target interactions can facilitate the development of efficient biosensor with high specificity and affinity. In this work, we present in silico, i.e. structural similarity, molecular docking and molecular dynamics selection of the aptamer with sufficient binding properties for acetamiprid (ACE), a nicotine-like pesticide, and its use to design aptamer-modified magnetic beads bearing ferrocene co-immobilized label for capacitive detection of ACE. Taking advantages of the aptamer higher stability and binding affinity, the specific properties of magnetic beads and the redox properties of ferrocene moiety, the developed aptasensor showed promising analytical performances for ACE detection, using electrochemical capacitance spectroscopy, with a linear response ranging from 1 fM to 100 pM and a limit of detection of 0.94 fM (S/N = 3). Furthermore, it was successfully applied to detect ACE in fortified tomatoes samples, proving a promising approach for routine detection of pesticide in real agricultural samples.
    MeSH term(s) Molecular Docking Simulation ; Metallocenes/chemistry ; Aptamers, Nucleotide/chemistry ; Pesticides/analysis ; Biosensing Techniques/methods ; Magnetic Phenomena ; Limit of Detection ; Electrochemical Techniques/methods
    Chemical Substances acetamiprid (5HL5N372P0) ; ferrocene (U96PKG90JQ) ; Metallocenes ; Aptamers, Nucleotide ; Pesticides
    Language English
    Publishing date 2023-03-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.124445
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Highly sensitive capacitance-based nitrite sensing using polydopamine/AuNPs-modified screen-printed carbon electrode.

    Algethami, Faisal K / Rabti, Amal / Mastouri, Mohamed / Abdulkhair, Babiker Y / Ben Aoun, Sami / Raouafi, Noureddine

    RSC advances

    2023  Volume 13, Issue 31, Page(s) 21336–21344

    Abstract: Regulatory bodies play a crucial role in establishing limits for food additives to ensure food quality and safety of food products, as excessive usage poses risks to consumers. In the context of processed animal-based foodstuffs, nitrite is commonly ... ...

    Abstract Regulatory bodies play a crucial role in establishing limits for food additives to ensure food quality and safety of food products, as excessive usage poses risks to consumers. In the context of processed animal-based foodstuffs, nitrite is commonly utilized as a means to slow down bacterial degradation. In this study, we have successfully leveraged the redox activity of an electrochemically deposited polydopamine (pDA) film onto gold nanoparticle (AuNP)-modified screen-printed electrodes (SPCE) to develop a sensitive and versatile methodology for the detection of nitrite using redox capacitance spectroscopy. By exploiting the interaction of the AuNPs/pDA electroactive interface with the target nitrite ions, we observed distinct changes in the redox distribution, subsequently leading to modifications in the associated redox capacitance. This alteration enables the successful detection of nitrite, exhibiting a linear response within the concentration range of 10 to 500 μM, with a limit of detection of 1.98 μM (S/N = 3). Furthermore, we applied the developed sensor to analyze nitrite levels in processed meats, yielding good recoveries. These results demonstrate the potential of our approach as a promising method for routine detection of ions.
    Language English
    Publishing date 2023-07-17
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra03898j
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Nanostructured carbon electrode modified with N-doped graphene quantum dots-chitosan nanocomposite: a sensitive electrochemical dopamine sensor.

    Ben Aoun, Sami

    Royal Society open science

    2017  Volume 4, Issue 11, Page(s) 171199

    Abstract: A highly selective and sensitive dopamine electrochemical sensor based on nitrogen-doped graphene quantum dots-chitosan nanocomposite-modified nanostructured screen printed carbon electrode is presented, for the first time. Graphene quantum dots were ... ...

    Abstract A highly selective and sensitive dopamine electrochemical sensor based on nitrogen-doped graphene quantum dots-chitosan nanocomposite-modified nanostructured screen printed carbon electrode is presented, for the first time. Graphene quantum dots were prepared via microwave-assisted hydrothermal reaction of glucose, and nitrogen doping was realized by introducing ammonia in the reaction mixture. Chitosan incorporation played a significant role towards the selectivity of the prepared sensor by hindering the ascorbic acid interference and enlarging the peak potential separation between dopamine and uric acid. The proposed sensor's performance was shown to be superior to several recently reported investigations. The as-prepared CS/N,GQDs@SPCE exhibited a high sensitivity (i.e. ca. 418 µA mM cm
    Language English
    Publishing date 2017-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2787755-3
    ISSN 2054-5703
    ISSN 2054-5703
    DOI 10.1098/rsos.171199
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Atypical presentation of bilateral iridoschisis with abnormal visibility of iris vessels: Role of anterior segment optical coherence tomography.

    Ben Aoun, Safa / Hachicha, Ines / Bouraoui, Rim / Matri, Khaled El / Limaiem, Rim / Matri, Leila El

    European journal of ophthalmology

    2023  Volume 34, Issue 2, Page(s) NP38–NP42

    Abstract: Purpose: To describe clinical and anterior segment optical coherence tomography (AS-OCT) findings in a patient with bilateral iridoschisis and unilateral angle closure glaucoma (ACG) associated with abnormal visibility of iris vessels.: Case ... ...

    Abstract Purpose: To describe clinical and anterior segment optical coherence tomography (AS-OCT) findings in a patient with bilateral iridoschisis and unilateral angle closure glaucoma (ACG) associated with abnormal visibility of iris vessels.
    Case presentation: A 67-year-old male patient with a history of red and painful left eye (LE) one year earlier, presented to our ophthalmology department for a routine examination.Ophthalmic examination of the right eye revealed narrow anterior chamber with sectorial iris atrophy associated to abnormal visibility of an iris vessel. Intraocular pressure (IOP) was 12 mmHg with normal optic disc appearance. LE anterior chamber was narrow with diffuse iris atrophy and abnormal vessels visibility. IOP was 28 mmHg with an important optic disc excavation. On gonioscopy, angle was narrow without neovessels nor synechiae. AS-OCT of both eyes revealed shallow angles, iris splitting with material release in the anterior chamber, while pigmented epithelium was preservedAnti-glaucoma eye drops were prescribed and peripheral laser iridotomy was performed in both eyes with decreased IOP at 14 mmHg in the LE.
    Conclusion: Iridoschisis is a rare ocular condition characterized by a separation between the anterior and posterior layers of iris stroma with several clinical presentations, and may be associated with abnormal visibility of iris vessels in some cases. The diagnosis of iridoschisis may be challenging and AS-OCT can be a very useful tool to confirm the diagnosis in atypical presentations and to detect associated angle closure.
    MeSH term(s) Male ; Humans ; Aged ; Tomography, Optical Coherence/methods ; Iris/diagnostic imaging ; Iris/pathology ; Iris Diseases/diagnosis ; Iris Diseases/complications ; Anterior Chamber/pathology ; Intraocular Pressure ; Gonioscopy ; Glaucoma, Angle-Closure/diagnosis ; Atrophy/pathology ; Anterior Eye Segment/diagnostic imaging ; Anterior Eye Segment/pathology
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721231206792
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3342: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Older people living alone at home with terminal cancer.

    Aoun, S / Deas, K / Skett, K

    European journal of cancer care

    2016  Volume 25, Issue 3, Page(s) 356–364

    Abstract: This study describes the lived experiences of older people coping with terminal cancer and living alone, focusing on how they face challenges of the biographical life changes from their disease progression. Face-to-face semi-structured interviews were ... ...

    Abstract This study describes the lived experiences of older people coping with terminal cancer and living alone, focusing on how they face challenges of the biographical life changes from their disease progression. Face-to-face semi-structured interviews were conducted in two phases with palliative care clients of a community-based service in Western Australia (2009-2011): Brief interviews with 43 cancer patients who live alone and then in-depth interviews with 8 of them. Using biographical disruption as the analytical framework for interpreting the qualitative data, four main themes emerged: Biographical disruption: adjusting to change; Biographical continuity: preserving normality; Biographical reconstruction: redefining normality; and Biographical closure: facing the end. Biographical disruption was a suitable framework for analysis, permitting identification of the biographical disruptions of the individual's world and the reframing that is undertaken by the individual to maintain autonomy and independence while acknowledging and accepting their closeness to death. Understanding the factors associated with the individual's need to maintain their own identity will enable nurses working with this population to tailor support plans that meet the individuals' needs while maintaining or restoring the person's sense of self. Interventions that directly address end-of-life suffering and bolster sense of dignity and personhood need to be considered.
    MeSH term(s) Adaptation, Psychological ; Aged ; Aged, 80 and over ; Disease Progression ; Family/psychology ; Female ; Friends ; Humans ; Independent Living ; Interpersonal Relations ; Life Change Events ; Loneliness/psychology ; Male ; Middle Aged ; Neoplasms/psychology ; Patient Acceptance of Health Care ; Single Person/psychology ; Social Support ; Spirituality ; Terminally Ill/psychology ; Western Australia
    Language English
    Publishing date 2016-05
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1303114-4
    ISSN 1365-2354 ; 0961-5423 ; 1360-5801
    ISSN (online) 1365-2354
    ISSN 0961-5423 ; 1360-5801
    DOI 10.1111/ecc.12314
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3347: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top