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  1. Article ; Online: The International Commission on Radiological Protection: Working Toward Keeping Recommendations Fit for Purpose.

    Applegate, Kimberly E

    Journal of the American College of Radiology : JACR

    2023  Volume 20, Issue 7, Page(s) 721–722

    MeSH term(s) Radiation Protection ; International Agencies
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2023.02.026
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  2. Book: Evidence based imaging

    Medina, L. Santiago / Blackmore, Christopher C. / Applegate, Kimberly E.

    improving the quality of imaging in patient care

    2011  

    Title variant Evidence-based imaging
    Author's details L. Santiago Medina ; C. Craig Blackmore ; Kimberly E. Applegate
    Keywords Diagnostic Imaging ; Evidence-Based Medicine
    Language English
    Size XX, 680 S. : Ill., graph. Darst.
    Edition Rev. ed.
    Publisher Springer
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016839622
    ISBN 978-1-4419-7776-2 ; 9781441977779 ; 1-4419-7776-7 ; 1441977775
    Database Catalogue ZB MED Medicine, Health

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    2011 A 2114 order for loan Magazin

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  3. Book: Evidence based imaging in pediatrics

    Medina, L. Santiago / Applegate, Kimberly E. / Blackmore, Christopher C.

    optimizing imaging in pediatric patient care

    2010  

    Author's details L. Santiago Medina ; Kimberly E. Applegate ; C. Craig Blackmore
    Language English
    Size XXII, 665 S. : Ill., graph. Darst., 26 cm
    Publisher Springer
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Formerly CIP Uk. - Includes bibliographical references and index
    HBZ-ID HT016993350
    ISBN 978-1-4419-0921-3 ; 1-4419-0921-4 ; 9781441909220 ; 1441909222
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Protection of patients in diagnostic and interventional medical imaging: collaboration is the key.

    Applegate, Kimberly E

    Health physics

    2015  Volume 108, Issue 2, Page(s) 221–223

    Abstract: The radiology community (medical physicists, radiologic technologists, radiologists, and interventional proceduralists) has led the educational and awareness efforts in the medical arena to reduce radiation dose to patients through effective ... ...

    Abstract The radiology community (medical physicists, radiologic technologists, radiologists, and interventional proceduralists) has led the educational and awareness efforts in the medical arena to reduce radiation dose to patients through effective collaborations that bridge traditional medical specialty silos to reach health worker stakeholders. These successful collaborations have also included both vendors and regulators, with the overarching goal of radiation protection of patients (justification, optimization, and use of dose reference levels). This focus on patients often raises overall safety awareness and lowers occupational radiation doses as well. It is critical that the entire radiology community continue to act as leaders in these radiation safety efforts for both employees and patients. In order to be successful, it is important to understand safety culture and the growing, worldwide, multimedia resources that are available. There is little time or budget to recreate or duplicate training materials or risk communication information that may already exist. Together with the increasingly fast-paced and demanding healthcare environment and sharp focus on quality, it has never been more important to understand how to achieve better quality care for radiology departments. It is also important to measure and report quality for many customers, including patients, referring providers, and many other stakeholders. This short report will briefly define safety culture and describe methods for using collective learning tools that document radiation protection of patients in diagnostic and interventional imaging. These tools include the use of imaging modality registries, such as the Computed Tomography Does Index Registry, peer review of imaging reports, the use of clinical decision support, and guidelines. Finally, the Image Gently and Image Wisely campaigns provide examples of cross-disciplinary collaboration to improve radiation protection of patients.
    MeSH term(s) Communication ; Decision Support Systems, Clinical ; Diagnostic Imaging/adverse effects ; Diagnostic Imaging/methods ; Health Policy ; Humans ; Patient Safety ; Radiation Dosage ; Radiation Monitoring/methods ; Radiation Protection/methods ; Radiology/methods ; Radiology Department, Hospital ; Risk ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2015-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2406-5
    ISSN 1538-5159 ; 0017-9078
    ISSN (online) 1538-5159
    ISSN 0017-9078
    DOI 10.1097/HP.0000000000000232
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    Zs.MO 253: Show issues

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  5. Article ; Online: Radiological protection in human research ethics using a case study: toward update of the ICRP Publication 62.

    Kurihara, Chieko / Applegate, Kimberly E / Jeong, Jee Hyang / Akahane, Keiichi / Kang, Keon Wook

    Journal of radiological protection : official journal of the Society for Radiological Protection

    2023  Volume 43, Issue 4

    Abstract: The benefits of biomedical research involving humans are well recognised, along with the need for conformity to international standards of science and ethics. When human research involves radiation imaging procedures or radiotherapy, an extra level of ... ...

    Abstract The benefits of biomedical research involving humans are well recognised, along with the need for conformity to international standards of science and ethics. When human research involves radiation imaging procedures or radiotherapy, an extra level of expert review should be provided from the point of view of radiological protection. The relevant publication of the International Commission for Radiological Protection (ICRP) is now three decades old and is currently undergoing an update. This paper aims to provoke discussions on how the risks of radiation dose and the benefits of research should be assessed, using a case study of diagnostic radiology involving volunteers for whom there is no direct benefit. Further, the paper provides the current understanding of key concepts being considered for review and revision-such as the dose constraint and the novel research methods on the horizon, including radiation biology and epidemiology. The analysis revisits the perspectives described in the ICRP Publication 62, and considers the recent progress in both radiological protection ethics and medical research ethics.
    MeSH term(s) Humans ; Radiation Protection/methods ; Radiology ; Ethics, Research ; International Agencies
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 639411-5
    ISSN 1361-6498 ; 0952-4746
    ISSN (online) 1361-6498
    ISSN 0952-4746
    DOI 10.1088/1361-6498/ad04f0
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  6. Article ; Online: Epidemiological Support of the Linear Nonthreshold Model in Radiological Protection: Implications of the National Council on Radiation Protection and Measurements Commentary 27 for the Radiologist.

    Applegate, Kimberly E / Shore, Roy E / Dauer, Lawrence T

    Journal of the American College of Radiology : JACR

    2020  Volume 17, Issue 12, Page(s) 1695–1697

    MeSH term(s) Humans ; Linear Models ; Neoplasms, Radiation-Induced ; Radiation Protection ; Radiologists
    Language English
    Publishing date 2020-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2020.06.010
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  7. Article ; Online: Image Gently: A Decade of International Collaborations to Promote Appropriate Imaging for Children.

    Applegate, Kimberly E / Frush, Donald P

    Journal of the American College of Radiology : JACR

    2017  Volume 14, Issue 7, Page(s) 956–957

    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2017.04.039
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  8. Article ; Online: The ICRP, MELODI, and ALLIANCE workshop on effects of ionizing radiation exposure in offspring and next generations: a summary of discussions.

    Degenhardt, Ämilie / Sreetharan, Shayenthiran / Amrenova, Aidana / Adam-Guillermin, Christelle / Dekkers, Fieke / Dumit, Sara / Frelon, Sandrine / Horemans, Nele / Laurier, Dominique / Liutsko, Liudmila / Salomaa, Sisko / Schneider, Thierry / Hande, Manoor P / Wakeford, Richard / Applegate, Kimberly E

    International journal of radiation biology

    2024  , Page(s) 1–11

    Abstract: Purpose: Task Group 121 - Effects of ionizing radiation exposure in offspring and next generations - is a task group under the Committee 1 of the International Commission on Radiological Protection (ICRP), approved by the Main Commission on 18th ... ...

    Abstract Purpose: Task Group 121 - Effects of ionizing radiation exposure in offspring and next generations - is a task group under the Committee 1 of the International Commission on Radiological Protection (ICRP), approved by the Main Commission on 18th November 2021. The main goals of Task Group 121 are to (1) review and update the scientific literature of relevance to radiation-related effects in the offspring of parent(s) exposed to ionizing radiation in both human and non-human biota; (2) to assess preconceptional and intrauterine effects of radiation exposure and related morbidity and mortality; and, (3) to provide advice about the level of evidence and how to consider these preconceptional and postconceptional effects in the system of radiological protection for humans and non-human biota.
    Methods: The Task Group is reviewing relevant literature since Publication 90 'Biological effects after prenatal irradiation (embryo and fetus)' (2003) and will include radiation-related effects on future generations in humans, animals, and plants. This review will be conducted to account for the health effects on offspring and subsequent generations in the current system of radiological protection. Radiation detriment calculation will also be reviewed. Finally, preliminary recommendations will be made to update the integration of health effects in offspring and next generations in the system of radiological protection.
    Results: A Workshop, jointly organized by ICRP Task Group 121 and European Radiation Protection Research Platforms MELODI and ALLIANCE was held in Budapest, Hungary, from 31st May to 2nd June 2022. Participants discussed four important topics: (1) hereditary and epigenetic effects due to exposure of the germ cell line (preconceptional exposure), (2) effects arising from exposure of the embryo and fetus (intrauterine exposure), (3) transgenerational effects on biota, and (4) its potential impact on the system of radiological protection.
    Conclusions: Based on the discussions and presentations during the breakout sessions, newer publications, and gaps on the current scientific literature were identified. For instance, there are some ongoing systematic reviews and radiation epidemiology reviews of intrauterine effects. There are newer methods of Monte Carlo simulation for fetal dosimetry, and advances in radiation genetics, epigenetics, and radiobiology studies. While the current impact of hereditary effects on the global detriment was reported as small, the questions surrounding the effects of radiation exposure on offspring and the next generation are crucial, recurring, and with a major focus on exposed populations. This article summarizes the workshop discussions, presentations, and conclusions of each topic and introduces the special issue of the International Journal of Radiation Biology resulting from the discussions of the meeting.
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 3065-x
    ISSN 1362-3095 ; 0020-7616 ; 0955-3002
    ISSN (online) 1362-3095
    ISSN 0020-7616 ; 0955-3002
    DOI 10.1080/09553002.2024.2306335
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  9. Article ; Online: Radiation exposures in pregnancy, health effects and risks to the embryo/foetus-information to inform the medical management of the pregnant patient.

    Applegate, Kimberly E / Findlay, Úna / Fraser, Louise / Kinsella, Yvonne / Ainsbury, Liz / Bouffler, Simon

    Journal of radiological protection : official journal of the Society for Radiological Protection

    2021  Volume 41, Issue 4

    Abstract: Generally, intentional exposure of pregnant women is avoided as far as possible in both medical and occupational situations. This paper aims to summarise available information on sources of radiation exposure of the embryo/foetus primarily in medical ... ...

    Abstract Generally, intentional exposure of pregnant women is avoided as far as possible in both medical and occupational situations. This paper aims to summarise available information on sources of radiation exposure of the embryo/foetus primarily in medical settings. Accidental and unintended exposure is also considered. Knowledge on the effects of radiation exposure on the developing embryo/foetus remains incomplete-drawn largely from animal studies and two human cohorts but a summary is provided in relation to the key health endpoints of concern, severe foetal malformations/death, future cancer risk, and future impact on cognitive function. Both the specific education and training and also the literature regarding medical management of pregnant females is in general sparse, and consequently the justification and optimisation approaches may need to be considered on a case by case basis. In collating and reviewing this information, several suggestions for future basic science research, education and training, and radiation protection practice are identified.
    MeSH term(s) Animals ; Female ; Fetus ; Humans ; Pregnancy ; Pregnant Women ; Radiation Exposure/adverse effects ; Radiation Protection ; Risk
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 639411-5
    ISSN 1361-6498 ; 0952-4746
    ISSN (online) 1361-6498
    ISSN 0952-4746
    DOI 10.1088/1361-6498/ac1c95
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  10. Article ; Online: Intussusception in children: evidence-based diagnosis and treatment.

    Applegate, Kimberly E

    Pediatric radiology

    2009  Volume 39 Suppl 2, Page(s) S140–3

    MeSH term(s) Child ; Enema/methods ; Enema/trends ; Evidence-Based Medicine/trends ; Humans ; Intussusception/diagnosis ; Intussusception/therapy ; Pediatrics/methods ; Pediatrics/trends ; Radiography, Abdominal/methods ; Radiography, Abdominal/trends ; Ultrasonography/methods ; Ultrasonography/trends
    Language English
    Publishing date 2009-03-24
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 124459-0
    ISSN 1432-1998 ; 0301-0449
    ISSN (online) 1432-1998
    ISSN 0301-0449
    DOI 10.1007/s00247-009-1178-9
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