Article ; Online: An electrochemical genomagnetic assay for detection of SARS-CoV-2 and Influenza A viruses in saliva.
2024 Volume 255, Page(s) 116210
Abstract: Viral respiratory infections represent a major threat to the population's health globally. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 disease and in some cases the symptoms can be confused with Influenza disease caused ... ...
| Abstract | Viral respiratory infections represent a major threat to the population's health globally. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 disease and in some cases the symptoms can be confused with Influenza disease caused by the Influenza A viruses. A simple, fast, and selective assay capable of identifying the etiological agent and differentiating the diseases is essential to provide the correct clinical management to the patient. Herein, we described the development of a genomagnetic assay for the selective capture of viral RNA from SARS-CoV-2 and Influenza A viruses in saliva samples and employing a simple disposable electrochemical device for gene detection and quantification. The proposed method showed excellent performance detecting RNA of SARS-CoV-2 and Influenza A viruses, with a limit of detection (LoD) and limit of quantification (LoQ) of 5.0 fmol L |
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| MeSH term(s) | Humans ; SARS-CoV-2/genetics ; COVID-19/diagnosis ; Influenza A virus/genetics ; Influenza, Human/diagnosis ; Saliva ; Reproducibility of Results ; Biosensing Techniques | |||||
| Language | English | |||||
| Publishing date | 2024-03-24 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 1011023-9 | |||||
| ISSN | 1873-4235 ; 0956-5663 | |||||
| ISSN (online) | 1873-4235 | |||||
| ISSN | 0956-5663 | |||||
| DOI | 10.1016/j.bios.2024.116210 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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