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  1. Book ; Online: High-Precision 4D Tracking with Large Pixels using Thin Resistive Silicon Detectors

    Arcidiacono, R. / Borghi, G. / Boscardin, M. / Cartiglia, N. / Vignali, M. Centis / Costa, M. / Betta, G-F. Dalla / Ferrero, M. / Ficorella, F. / Gioachin, G. / Lanteri, L. / Mandurrino, M. / Menzio, L. / Mulargia, R. / Pancheri, L. / Paternoster, G. / Rojas, A. / Sadrozinski, H-F W. / Seiden, A. /
    Siviero, F. / Sola, V. / Tornago, M.

    2022  

    Abstract: The basic principle of operation of silicon sensors with resistive read-out is built-in charge sharing. Resistive Silicon Detectors (RSD, also known as AC-LGAD), exploiting the signals seen on the electrodes surrounding the impact point, achieve ... ...

    Abstract The basic principle of operation of silicon sensors with resistive read-out is built-in charge sharing. Resistive Silicon Detectors (RSD, also known as AC-LGAD), exploiting the signals seen on the electrodes surrounding the impact point, achieve excellent space and time resolutions even with very large pixels. In this paper, a TCT system using a 1064 nm picosecond laser is used to characterize sensors from the second RSD production at the Fondazione Bruno Kessler. The paper first introduces the parametrization of the errors in the determination of the position and time coordinates in RSD, then outlines the reconstruction method, and finally presents the results. Three different pixel sizes are used in the analysis: 200 x 340, 450 x 450, and 1300 x 1300 microns^2. At gain = 30, the 450 x 450 microns^2 pixel achieves a time jitter of 20 ps and a spatial resolution of 15 microns concurrently, while the 1300 x 1300 microns^2 pixel achieves 30 ps and 30 micron, respectively. The implementation of cross-shaped electrodes improves considerably the response uniformity over the pixel surface.

    Comment: 28 pages, 23 figures submitted to NIMA
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment
    Subject code 621
    Publishing date 2022-11-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Impiego del tosilato di bretilio nella fibrillazione ventricolare.

    Arcidiacono, R

    La Clinica terapeutica

    1978  Volume 84, Issue 3, Page(s) 253–266

    Title translation Use of bretylium tosylate in ventricular fibrillation.
    MeSH term(s) Adult ; Aged ; Bretylium Compounds/therapeutic use ; Bretylium Tosylate/therapeutic use ; Clinical Trials as Topic ; Drug Evaluation ; Humans ; Middle Aged ; Ventricular Fibrillation/drug therapy
    Chemical Substances Bretylium Compounds ; Bretylium Tosylate (78ZP3YR353)
    Language Italian
    Publishing date 1978-02-15
    Publishing country Italy
    Document type Clinical Trial ; English Abstract ; Journal Article
    ZDB-ID 123320-8
    ISSN 1972-6007 ; 0009-9074
    ISSN (online) 1972-6007
    ISSN 0009-9074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: First application of machine learning algorithms to the position reconstruction in Resistive Silicon Detectors

    Siviero, Federico / Arcidiacono, Roberta / Cartiglia, Nicolò / Costa, Marco / Ferrero, Marco / Mandurrino, Marco / Sola, Valentina / Staiano, Amedeo / Tornago, Marta

    2020  

    Abstract: RSDs (Resistive AC-Coupled Silicon Detectors) are n-in-p silicon sensors based on the LGAD (Low-Gain Avalanche Diode) technology, featuring a continuous gain layer over the whole sensor area. The truly innovative feature of these sensors is that the ... ...

    Abstract RSDs (Resistive AC-Coupled Silicon Detectors) are n-in-p silicon sensors based on the LGAD (Low-Gain Avalanche Diode) technology, featuring a continuous gain layer over the whole sensor area. The truly innovative feature of these sensors is that the signal induced by an ionising particle is seen on several pixels, allowing the use of reconstruction techniques that combine the information from many read-out channels. In this contribution, the first application of a machine learning technique to RSD devices is presented. The spatial resolution of this technique is compared to that obtained with the standard RSD reconstruction methods that use analytical descriptions of the signal sharing mechanism. A Multi-Output regressor algorithm, trained with a combination of simulated and real data, leads to a spatial resolution of less than 2 $\mu m$ for a sensor with a 100 $\mu m$ pixel. The prospects of future improvements are also discussed.
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment
    Subject code 621
    Publishing date 2020-11-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: Silicon Sensors for Future Particle Trackers

    Cartiglia, N. / Arcidiacono, R. / Borghi, G. / Boscardin, M. / Costa, M. / Galloway, Z. / Fausti, F. / Ferrero, M. / Ficorella, F. / Mandurrino, M. / Mazza, S. / Olave, E. J. / Paternoster, G. / Siviero, F. / Sadrozinski, H. F-W. / Sola, V. / Staiano, A. / Seiden, A. / Tornago, M. /
    Zhao, Y.

    2020  

    Abstract: Several future high-energy physics facilities are currently being planned. The proposed projects include high energy $e^+ e^-$ circular and linear colliders, hadron colliders and muon colliders, while the Electron-Ion Collider (EIC) has already been ... ...

    Abstract Several future high-energy physics facilities are currently being planned. The proposed projects include high energy $e^+ e^-$ circular and linear colliders, hadron colliders and muon colliders, while the Electron-Ion Collider (EIC) has already been approved for construction at the Brookhaven National Laboratory. Each proposal has its own advantages and disadvantages in term of readiness, cost, schedule and physics reach, and each proposal requires the design and production of specific new detectors. This paper first presents the performances required to the future silicon tracking systems at the various new facilities, and then it illustrates a few possibilities for the realization of such silicon trackers. The challenges posed by the future facilities require a new family of silicon detectors, where features such as impact ionization, radiation damage saturation, charge sharing, and analog readout are exploited to meet these new demands.
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment
    Subject code 621
    Publishing date 2020-03-31
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Endoscopic Treatment of Broncho-Esophageal Fistulae: Personal Experience

    Arcidiacono, R. / Grosso, C. / Rossi, A. / Gambitta, P.

    Endoscopy

    2008  Volume 25, Issue 08, Page(s) 547–548

    Language English
    Publishing date 2008-03-17
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-1010397
    Database Thieme publisher's database

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  6. Article: Detection of a novel allergen in raw tomato.

    Asero, R / Mistrello, G / Roncarolo, D / Amato, S / Arcidiacono, R / Fortunato, D

    Journal of investigational allergology & clinical immunology

    2008  Volume 18, Issue 5, Page(s) 397–400

    Abstract: The study reports a case of "pure" tomato allergy in an adult female. The responsible allergen was partially characterized by immunoblot analysis, pepsin digestion, and heating. It had a molecular weight of about 9 kDa and was heat-labile and pepsin- ... ...

    Abstract The study reports a case of "pure" tomato allergy in an adult female. The responsible allergen was partially characterized by immunoblot analysis, pepsin digestion, and heating. It had a molecular weight of about 9 kDa and was heat-labile and pepsin-resistant, thus confirming the clinical history. Unfortunately, due to the failure of both 2-dimensional electrophoresis analysis and N-terminal sequencing experiments, it was not possible to characterize the protein further. Based on a comparison with currently known tomato allergens, this seems to be a novel allergen protein.
    MeSH term(s) Abdominal Pain ; Antigens, Plant/immunology ; Antigens, Plant/isolation & purification ; Antigens, Plant/metabolism ; Blotting, Western ; Diarrhea ; Epitopes ; Female ; Food Hypersensitivity/etiology ; Food Hypersensitivity/immunology ; Food Hypersensitivity/physiopathology ; Humans ; Immunoglobulin E/blood ; Lycopersicon esculentum/immunology ; Middle Aged ; Plant Extracts/isolation & purification ; Rhinitis, Allergic, Perennial/complications ; Rhinitis, Allergic, Perennial/immunology ; Rhinitis, Allergic, Perennial/physiopathology ; Vegetable Proteins/immunology ; Vegetable Proteins/isolation & purification ; Vegetable Proteins/metabolism
    Chemical Substances Antigens, Plant ; Epitopes ; Plant Extracts ; Vegetable Proteins ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2008
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 1128657-x
    ISSN 1018-9068
    ISSN 1018-9068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Resistive AC-Coupled Silicon Detectors

    Tornago, M. / Arcidiacono, R. / Cartiglia, N. / Costa, M. / Ferrero, M. / Mandurrino, M. / Siviero, F. / Sola, V. / Staiano, A. / Apresyan, A. / Di Petrillo, K. / Heller, R. / Los, S. / Borghi, G. / Boscardin, M. / Betta, G-F Dalla / Ficorella, F. / Pancheri, L. / Paternoster, G. /
    Sadrozinski, H. / Seiden, A.

    principles of operation and first results from a combined analysis of beam test and laser data

    2020  

    Abstract: This paper presents the principles of operation of Resistive AC-Coupled Silicon Detectors (RSDs) and measurements of the temporal and spatial resolutions using a combined analysis of laser and beam test data. RSDs are a new type of n-in-p silicon sensor ... ...

    Abstract This paper presents the principles of operation of Resistive AC-Coupled Silicon Detectors (RSDs) and measurements of the temporal and spatial resolutions using a combined analysis of laser and beam test data. RSDs are a new type of n-in-p silicon sensor based on the Low-Gain Avalanche Diode (LGAD) technology, where the $n^+$ implant has been designed to be resistive, and the read-out is obtained via AC-coupling. The truly innovative feature of RSD is that the signal generated by an impinging particle is shared isotropically among multiple read-out pads without the need for floating electrodes or an external magnetic field. Careful tuning of the coupling oxide thickness and the $n^+$ doping profile is at the basis of the successful functioning of this device. Several RSD matrices with different pad width-pitch geometries have been extensively tested with a laser setup in the Laboratory for Innovative Silicon Sensors in Torino, while a smaller set of devices have been tested at the Fermilab Test Beam Facility with a 120 GeV/c proton beam. The measured spatial resolution ranges between $2.5\; \mu m$ for 70-100 pad-pitch geometry and $17\; \mu m$ with 200-500 matrices, a factor of 10 better than what is achievable in binary read-out ($bin\; size/ \sqrt{12}$). Beam test data show a temporal resolution of $\sim 40\; ps$ for 200-$\mu m$ pitch devices, in line with the best performances of LGAD sensors at the same gain.

    Comment: 34 pages, 33 figures
    Keywords Physics - Instrumentation and Detectors
    Subject code 621
    Publishing date 2020-07-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Endoscopic treatment of anastomotic biliary stenosis in patients with orthotopic liver transplantation.

    Rossi, A / Grosso, C / Zanasi, G / Gambitta, P / Bini, M / de Carlis, L / Arcidiacono, R

    Diagnostic and therapeutic endoscopy

    2008  Volume 2, Issue 2, Page(s) 93–97

    Abstract: The choledocho-choledochostomy stricture is one of the most frequent complications occurring after liver transplantation. Today endoscopic retrograde cholangiopancreatography may be considered one of the most common methodologic approaches for the ... ...

    Abstract The choledocho-choledochostomy stricture is one of the most frequent complications occurring after liver transplantation. Today endoscopic retrograde cholangiopancreatography may be considered one of the most common methodologic approaches for the diagnosis; at the same time it provides an effective treatment of the stenosis, avoiding more invasive surgery. Biliary flow through a strictured anastomosis definitely improves after endoscopic stenting which, in most cases, resolves the biliary obstruction syndrome; moreover, the stent could allow restoration of the anatomical and functional integrity of the common bile duct. We have successfully treated eight liver transplanted patients with biliary anastomotic stenosis by endoscopic stenting of the common bile duct or by balloon dilation (one patient). The stents were replaced every 3 to 4 months and then removed after 1 year of follow-up. We observed one patient with acute cholangitis due to the clogging of the prosthetic device.
    Language English
    Publishing date 2008-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1327325-5
    ISSN 1070-3608
    ISSN 1070-3608
    DOI 10.1155/DTE.2.93
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Effect of Endoscopic Sclerotherapy of Esophageal Varices on the Development of Gastric Varices

    Zanasi, G. / Rossi, A. / Grosso, C. / Bini, M. / Gambitta, P. / Pirone, Z. / Arcidiacono, R.

    Endoscopy

    2008  Volume 28, Issue 02, Page(s) 234–238

    Abstract: BACKGROUND AND STUDY AIMS: The effect of sclerotherapy of esophageal varices on the development of gastric varices is a controversial question. The aim of the present study was to evaluate prospectively the presence and development of gastric varices as ... ...

    Abstract BACKGROUND AND STUDY AIMS: The effect of sclerotherapy of esophageal varices on the development of gastric varices is a controversial question. The aim of the present study was to evaluate prospectively the presence and development of gastric varices as a consequence of esophageal variceal sclerotherapy. PATIENTS AND METHODS: We prospectively studied 227 patients, all of whom had liver cirrhosis at the time of the first bleeding episode due to esophageal varices. All patients were treated with emergency endoscopic sclerotherapy, and further courses of sclerotherapy to eradicate the varices were given at seven-day intervals for three sessions, and then every fifteen days until eradication was complete. At the time of inclusion in the study, patients were divided in two groups: group A, with initial gastric varices, and group B, without any gastric varices initially. RESULTS: Group A included 138 patients (60.8 %), in 99 of whom (71.7 %) disappearance of the gastric varices was observed. In 63 cases (63.6 %) the varices were eliminated during the sclerotherapy treatment, before the eradication of esophageal varices; in 36 cases (36.4 %), the gastric varices disappeared after the eradication of the esophageal varices. Group B included 89 patients (32.9 %); in 78 of them (87.6 %), no appearance of gastric varices was observed, while in 11 (12.4 %), gastric varices appeared. CONCLUSIONS: From these data, it can be concluded that sclerotherapy of esophageal varices cannot be a determinant factor either for the appearance of gastric varices or for their subsequent risk of bleeding.
    Language English
    Publishing date 2008-03-17
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-1005434
    Database Thieme publisher's database

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  10. Article: The Use of a Long-Acting Somatostatin Analogue (Octreotide) for Prophylaxis of Acute Pancreatitis after Endoscopic Sphincterotomy

    Arcidiacono, R. / Gambitta, P. / Rossi, A. / Grosso, C. / Bini, M. / Zanasi, G.

    Endoscopy

    2008  Volume 26, Issue 09, Page(s) 715–718

    Abstract: Acute pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST). In addition, serum pancreatic enzymes increase without clinical symptoms in about 40-50 % of patients undergoing ... ...

    Abstract Acute pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (EST). In addition, serum pancreatic enzymes increase without clinical symptoms in about 40-50 % of patients undergoing these endoscopic procedures. We evaluated the potential of octreotide, a long-acting somatostatin analogue, to prevent these complications in patients who underwent EST for choledocholithiasis. 151 patients were randomly allocated to two groups (A and B). Group A was given 0.1 mg of octreotide subcutaneously 120 and 30 min before EST and four hours after; group B was given a placebo. Serum amylases (normal range 20-220 IU/1) were measured before premedication and 4, 24, and 48 hours after the end of endoscopy. After EST, the increase in the mean serum amylase was greater in the control group, but the difference was statistically significant only at the 48-hour measurement. There were five cases of acute pancreatitis in each group, with a trend (but not statistically significant) toward less severe pancreatitis in the treated group. In the control group, one patient with acute pancreatitis died. In conclusion, octreotide does not seem to prevent acute post-EST pancreatitis.
    Language English
    Publishing date 2008-03-17
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-2007-1009081
    Database Thieme publisher's database

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