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Article ; Online: Correspondence on 'Sentinel lymph node assessment in patients with atypical endometrial hyperplasia: a systematic review and meta-analysis' by Vieira-Serna et al.

Restaino, Stefano / Arcieri, Martina / Vizzielli, Giuseppe

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

2024 Volume 34, Issue 4, Page(s) 656

MeSH term(s)	Female ; Humans ; Sentinel Lymph Node/surgery ; Sentinel Lymph Node/pathology ; Endometrial Hyperplasia/pathology ; Sentinel Lymph Node Biopsy ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Endometrial Neoplasms/pathology ; Lymph Node Excision ; Neoplasm Staging
Language	English
Publishing date	2024-04-01
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Letter
ZDB-ID	1070385-8
ISSN	1525-1438 ; 1048-891X
ISSN (online)	1525-1438
ISSN	1048-891X
DOI	10.1136/ijgc-2024-005294
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Article ; Online: "Water or not water: That is the question." Analysis of costs and consumption of the operating theaters in a greener perspective.

Restaino, Stefano / Tius, Veronica / Arcieri, Martina / Biasioli, Anna / Pellecchia, Giulia / Driul, Lorenza / Vizzielli, Giuseppe

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

2024 Volume 165, Issue 3, Page(s) 1167–1171

Abstract: Objective: To compare the amounts of water and plastic used in surgical hand washing with medicated soaps and with alcohol-based products and to compare costs and consumption in a year, based on scheduled surgical activity.: Method: This ... ...

Abstract	Objective: To compare the amounts of water and plastic used in surgical hand washing with medicated soaps and with alcohol-based products and to compare costs and consumption in a year, based on scheduled surgical activity. Method: This retrospective study was carried out at Udine's Gynecology Operating Block from October to November 2022. We estimated the average amount of water with a graduated cylinder and the total cost of water usage based on euros/m Results: The daily amount of water using povidone-iodine, chlorhexidine-gluconate and alcohol-based antiseptic agents was 187.6, 140.7 and 0 L/day (P value = 0.001), respectively; A total of 69 000 L/year of water would be saved if alcohol-based products were routinely used. A single unit of an alcohol-based product allows three times as many handscrubs as any other product (P value = 0.001) with consequent reduction in plastic packaging. Conclusion: Despite the cost saving being negligible, choosing alcohol-based handrub over medicated soap handrub - on equal antiseptic efficacy grounds - could lead to a significant saving of water and plastic, thus making our operating theaters more environmentally friendly.
MeSH term(s)	Humans ; Retrospective Studies ; Operating Rooms/economics ; Hand Disinfection ; Anti-Infective Agents, Local/economics ; Anti-Infective Agents, Local/administration & dosage ; Povidone-Iodine/economics ; Povidone-Iodine/administration & dosage ; Water ; Chlorhexidine/economics ; Chlorhexidine/administration & dosage ; Chlorhexidine/analogs & derivatives ; Soaps/economics ; Female ; Costs and Cost Analysis ; Plastics ; Gynecologic Surgical Procedures/economics
Chemical Substances	Anti-Infective Agents, Local ; Povidone-Iodine (85H0HZU99M) ; Water (059QF0KO0R) ; Chlorhexidine (R4KO0DY52L) ; chlorhexidine gluconate (MOR84MUD8E) ; Soaps ; Plastics
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	80149-5
ISSN	1879-3479 ; 0020-7292
ISSN (online)	1879-3479
ISSN	0020-7292
DOI	10.1002/ijgo.15325
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Zs.A 355: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Simple hysterectomy versus radical hysterectomy in early-stage cervical cancer: A systematic review and meta-analysis.

Taliento, C / Scutiero, G / Arcieri, M / Pellecchia, G / Tius, V / Bogani, G / Petrillo, M / Pavone, M / Bizzarri, N / Driul, L / Greco, P / Scambia, G / Restaino, S / Vizzielli, G

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2024 Volume 50, Issue 4, Page(s) 108252

Abstract: Background: This systematic review (SR) and meta-analysis aims to compare the surgery-related results and oncological outcomes between SH and RH in patients with early-stage cervical cancer.: Method: We systematically searched databases including ... ...

Abstract	Background: This systematic review (SR) and meta-analysis aims to compare the surgery-related results and oncological outcomes between SH and RH in patients with early-stage cervical cancer. Method: We systematically searched databases including PubMed, Embase and Cochrane to collect studies that compared oncological and surgery-related outcomes between SH and RH groups in patients with stage IA2 and IB1 cervical cancer. A random-effect model calculated the weighted average difference of each primary outcome via Review Manager V.5.4. Result: Seven studies comprising 6977 patients were included into our study. For oncological outcomes, we found no statistical difference in recurrence rate [OR = 0.88; 95% CI (0.50, 1.57); P = 0.68] and Overall Survival (OS) [OR = 1.23; 95% CI (0.69, 2.19), P = 0.48]. No difference was detected in the prevalence of positive LVSI and lymph nodes metastasis between the two groups. Concerning surgery-related outcomes, the comprehensive effects revealed that the bladder injury [OR = 0.28; 95% CI (0.08, 0.94), P = 0.04] and bladder disfunction [OR = 0.10; 95% CI (0.02, 0.53), P = 0.007] of the RH group were higher compared to the SH group. Conclusion: This meta-analysis suggested there are no significant differences in terms of both recurrence rate and overall survival among patients with stage IA2-IB1 cervical cancer undergoing SH or RH, while the SH group has better surgery-related outcomes. These data confirm the need to narrow the indication for RH in early-stage cervical cancer.
MeSH term(s)	Female ; Humans ; Disease-Free Survival ; Uterine Cervical Neoplasms/surgery ; Uterine Cervical Neoplasms/pathology ; Neoplasm Staging ; Hysterectomy/methods ; Neoplasm Recurrence, Local/pathology ; Retrospective Studies
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2024.108252
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Zs.A 1149: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Rice cultivation in Italy under the threat of climatic change: Trends, technologies and research gaps

Arcieri, Marco / Ghinassi, Graziano

Irrigation and drainage. 2020 Oct., v. 69, no. 4

2020

Abstract: Italy is the largest rice‐producing country in the European Union: more than two‐thirds of Europe's rice with about 60% of the national production exported, mainly to Mediterranean countries and Eastern Europe. Rice production started around the middle ... ...

Abstract	Italy is the largest rice‐producing country in the European Union: more than two‐thirds of Europe's rice with about 60% of the national production exported, mainly to Mediterranean countries and Eastern Europe. Rice production started around the middle of the fifteenth century, influencing Italian distinguished cuisine. Specialized cultivation is higly skilled and accounts for 70–80% of the global rice farming surface. The crop is grown from April to October and extends over about 240 000 ha (1.4% of the total arable area of the country). The expected production is approximately 1.4 million tonnes (MT) of paddy rice; average yield is about 6 t ha¯¹, 85% of the surface being cropped with Japonica‐type varieties, the rest with Thaibonnet. In last 20 years, the cultivation area has increased by about 20%, making Italy an important rice‐exporting country, as the volume of exports reached 5% of total rice traded in the world and domestic consumption hardly exceeds 40% of total production. The main constraints in Italy are low temperature (at sowing and flowering time), diseases, weeds and red rice. Recent research has proved that the possibility exists to increase potential yield by means of varietal improvement, with emphasis on disease and lodging resistance, and better low‐temperature and dry‐conditions adaptability. © 2020 John Wiley & Sons, Ltd.
Keywords	European Union ; climate change ; cuisine ; cultivation area ; irrigation and drainage ; red rice ; rough rice ; temperature ; Eastern European region ; Italy
Language	English
Dates of publication	2020-10
Size	p. 517-530.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	NAL-AP-2-clean ; REVIEW
ZDB-ID	2047418-0
ISSN	1531-0361 ; 1531-0353
ISSN (online)	1531-0361
ISSN	1531-0353
DOI	10.1002/ird.2472
Database	NAL-Catalogue (AGRICOLA)

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Article: Spread and Potential Risks of Genetically Modified Organisms

Arcieri, Margherita

Agriculture and Agricultural Science Procedia. 2016, v. 8

2016

Abstract: Genetic engineering is a technique that allows to detect, isolate, multiply and transplant specific genes in another living organism. The introduction of genes in another living organism or other species is a process unstable and insecure with side ... ...

Abstract	Genetic engineering is a technique that allows to detect, isolate, multiply and transplant specific genes in another living organism. The introduction of genes in another living organism or other species is a process unstable and insecure with side effects and consequences difficult to predict on the recipient genome and interaction with the surrounding environment.The main proponent are big business owners of patents in the field of GMOs and other stakeholders, including some GMO growers and scientists, as well as international trading partners.The potential economic interests in relation to GMOs in the field of plant breeding are considerable, the world annual turnover of the seed market has now exceeded 35 billion Euros. Today the world market is dominated by only a handful of large operators. The same multinational companies operating in the food, plant protection chemicals, energy and pharmaceutical industries. This concentration allows a small group of corporations to exercise considerable control over the entire production chain of food and related products, thus putting at risk the freedom of choice, the accessibility of prices, open innovation and diversity genetics.The development and dissemination of GMOs through these centuries-old-traditions have been called the Green Revolution. The greater use of chemicals in agriculture offers the possibility of a higher gain, but requires a greater dose of herbicides over time, which makes it necessary to look for a more aggressive chemical solution.However, on the basis of objective evidence one can conclude that genetic engineering is not fundamentally new to these historical applications. The advent of genetic engineering marks a definitive break between the biotechnology of “old” and the “modern” conception.Among the arguments used more frequently to support the use of GMOs, is the need to fight hunger, to ensure the supply of food to a growing world population and the fight against climate change. The majority of genetically modified varieties currently on the market are grown for forage and feed for livestock, for meat and milk consumed in the Western World, or to produce biofuel or plastics.The increase in non-food use of edible agricultural products has pushed-up the prices of raw materials and foodstuffs on the world market, which has done nothing but exacerbate food insecurity and poverty in the world. The problems of the global food supply difficulties arise not so much from production to distribution since global production is equivalent to over 150% of global consumption. Consequently this requires a political and economic solution rather than agricultural innovation.
Keywords	biofuels ; biotechnology ; business enterprises ; climate change ; corporations ; energy ; food availability ; food chain ; food security ; food supply chain ; forage ; genes ; genetic engineering ; genetically modified organisms ; growers ; herbicides ; livestock feeds ; meat ; milk ; patents ; pharmaceutical industry ; plant breeding ; plant protection ; politics ; poverty ; prices ; raw materials ; risk ; scientists ; stakeholders ; world markets
Language	English
Size	p. 552-559.
Publishing place	Elsevier B.V.
Document type	Article
ISSN	2210-7843
DOI	10.1016/j.aaspro.2016.02.072
Database	NAL-Catalogue (AGRICOLA)

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Article: Water Resources and Soil Management In Italy

Arcieri, Marco

Irrigation and drainage. 2016 Apr., v. 65, no. 2

2016

Abstract: Italy has always had a long dramatic history of extreme events such as landslides, flooding, land degradation and drought. Much has been done in terms of prevention and monitoring but still there is much left to do, in particular introducing innovative ... ...

Abstract	Italy has always had a long dramatic history of extreme events such as landslides, flooding, land degradation and drought. Much has been done in terms of prevention and monitoring but still there is much left to do, in particular introducing innovative alert systems based on the integration of realâtime weather forecasting with national alert and protection systems. Recent drought events in the past decade have put new light on the pressing need to improve water use efficiency, introducing on one hand new criteria regarding water resources governance and management by water authorities and agencies involved in this, and on the other, fostering innovative techniques that may enable farmers to improve overall economic and sustainable production by adopting rigorous criteria in terms of managing techniques such as water scheduling. A great effort on this matter has been made by the National Association of Land Reclamation and Irrigation Consortia (ANBI), by introducing and spreading the use of the innovative IRRIFRAME software. IRRIFRAME is an expert system the use of which has allowed the saving up to today, according to data published by ANBI, something between 15 and 25% of water for farmers, increasing both the quantity and quality of agricultural production at the same time.
Keywords	computer software ; drought ; farmers ; irrigation ; land degradation ; landslides ; monitoring ; water management ; water resources ; water use efficiency ; weather forecasting ; Italy
Language	English
Dates of publication	2016-04
Size	p. 165-181.
Publishing place	John Wiley & Sons
Document type	Article
ZDB-ID	2047418-0
ISSN	1531-0353
ISSN	1531-0353
DOI	10.1002/ird.1985
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Locally advanced squamous cervical carcinoma (M0): management and emerging therapeutic options in the precision radiotherapy era.

Parisi, S / Sciacca, M / Ferrantelli, G / Chillari, F / Critelli, P / Venuti, V / Lillo, S / Arcieri, M / Martinelli, C / Pontoriero, A / Minutoli, F / Ercoli, A / Pergolizzi, S

Japanese journal of radiology

2023 Volume 42, Issue 4, Page(s) 354–366

Abstract: Squamous cervical carcinoma (SCC) requires particular attention in diagnostic and clinical management. New diagnostic tools, such as (positron emission tomography-magnetic resonance imaging) PET-MRI, consent to ameliorate clinical staging accuracy. The ... ...

Abstract	Squamous cervical carcinoma (SCC) requires particular attention in diagnostic and clinical management. New diagnostic tools, such as (positron emission tomography-magnetic resonance imaging) PET-MRI, consent to ameliorate clinical staging accuracy. The availability of new technologies in radiation therapy permits to deliver higher dose lowering toxicities. In this clinical scenario, new surgical concepts could aid in general management. Lastly, new targeted therapies and immunotherapy will have more room in this setting. The aim of this narrative review is to focus both on clinical management and new therapies in the precision radiotherapy era.
MeSH term(s)	Female ; Humans ; Positron-Emission Tomography ; Carcinoma, Squamous Cell/diagnostic imaging ; Carcinoma, Squamous Cell/radiotherapy ; Uterine Cervical Neoplasms/diagnostic imaging ; Uterine Cervical Neoplasms/radiotherapy ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Chemoradiotherapy/methods ; Neoplasm Staging
Language	English
Publishing date	2023-11-21
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	2488907-6
ISSN	1867-108X ; 1867-1071
ISSN (online)	1867-108X
ISSN	1867-1071
DOI	10.1007/s11604-023-01510-2
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Zs.A 2249: Show issues

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Article ; Online: Three-dimensional vision versus two-dimensional vision on laparoscopic performance of trainee surgeons: a systematic review and meta-analysis.

Restaino, S / Scutiero, G / Taliento, Cristina / Poli, A / Bernardi, G / Arcieri, M / Santi, E / Fanfani, F / Chiantera, V / Driul, L / Scambia, G / Greco, P / Vizzielli, G

Updates in surgery

2023 Volume 75, Issue 3, Page(s) 455–470

Abstract: Laparoscopic surgery underwent great improvements during the last few years. This review aims to compare the performance of Trainee Surgeons using 2D versus 3D/4 K laparoscopy. A systematic review of the literature was done on Pubmed, Embase, Cochrane's ... ...

Abstract	Laparoscopic surgery underwent great improvements during the last few years. This review aims to compare the performance of Trainee Surgeons using 2D versus 3D/4 K laparoscopy. A systematic review of the literature was done on Pubmed, Embase, Cochrane's Library and Scopus. The following words and key phrases have been searched: "Two-dimensional vision", "Three-dimensional vision", "2D and 3D laparoscopy", "Trainee surgeons". This systematic review was reported according to the PRISMA statement 2020. PROSPERO registration No. CRD42022328045. Twenty-two randomized controlled trials (RCTs) and two observational studies were included in the systematic review. Two trials were carried out in a clinical setting, and twenty-two trials were performed in a simulated setting. In studies involving the use of a box trainer, the number of errors in the 2D laparoscopic group was significantly higher than in the 3D laparoscopic group during the performance of FLS skill tasks: peg transfer (MD: -0.82; 95% CI - 1.17 to - 0.47; p < 0.00001), cutting (MD: - 1.09; 95% CI - 1.50 to - 0.69 p < 0.00001), suturing (MD: - 0.48; 95% CI - 0.83 to - 0.13 p = 0.007), However, in clinical studies, there was no significant difference in the time taken for laparoscopic total hysterectomy (MD: 8.71; 95% CI - 13.55 to 30.98; p = 0.44) and vaginal cuff closure (MD: 2.00; 95% CI - 0.72 to - 4.72; p = 0.15) between 2D group and 3D group. 3D laparoscopy facilitates learning for novice surgeons and shows improvements in their laparoscopic performance.
MeSH term(s)	Female ; Humans ; Surgeons ; Laparoscopy/methods ; Clinical Competence ; Learning ; Operative Time ; Imaging, Three-Dimensional/methods
Language	English
Publishing date	2023-02-22
Publishing country	Italy
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-023-01465-z
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Article ; Online: Is the sarcomatous component (homologous vs heterologous) the prognostic "driving force" in early-stage uterine carcinosarcomas? A retrospective multicenter study.

Rosati, A / Vargiu, V / Certelli, C / Arcieri, M / Vizza, E / Legge, F / Cosentino, F / Ferrandina, G / Fanfani, F / Scambia, G / Corrado, G

Journal of cancer research and clinical oncology

2023 Volume 149, Issue 9, Page(s) 6479–6488

Abstract: Purpose: Uterine carcinosarcomas (UCSs) are aggressive biphasic malignancies, with a carcinomatous/epithelial component and a sarcomatous/mesenchymal counterpart. The aim of this study was to evaluate the impact of the sarcomatous component (homologous ... ...

Abstract	Purpose: Uterine carcinosarcomas (UCSs) are aggressive biphasic malignancies, with a carcinomatous/epithelial component and a sarcomatous/mesenchymal counterpart. The aim of this study was to evaluate the impact of the sarcomatous component (homologous vs heterologous) on the overall survival (OS) and progression-free survival (PFS). Methods: This is a multicenter observational retrospective study conducted in patients with stage I and II UCSs. Results: Ninety-five women with histological diagnosis of early-stage UCSs were retrieved: 60 (63.2%) had tumors with homologous sarcomatous components, and 35 (36.8%) with heterologous. At univariate analysis, a stromal invasion ≥ 50%, the presence of clear cell, serous or undifferentiated carcinomatous component, the heterologous sarcomatous component and FIGO stage IB and II were shown to be variables with a statistically significant negative impact on PFS. Similarly, a depth of invasion ≥ 50%, the heterologous sarcomatous component and FIGO stage IB and II were statistically negative prognostic factors also concerning OS. At multivariate analysis, only the heterologous sarcomatous component was confirmed to be a statistically significant negative prognostic factor both on PFS (HR 2.362, 95% CI 1.207-4.623, p value = 0.012) and on OS (HR 1.950, 95% CI 1.032-3.684, p = 0.040). Conclusion: Carcinomatous and sarcomatous components both played a role in tumor progression and patients' survival. However, only the sarcomatous component retained a statistical significance at the multivariable model suggesting its preeminent prognostic role in early-stage UCSs.
MeSH term(s)	Humans ; Female ; Prognosis ; Retrospective Studies ; Carcinosarcoma/surgery ; Carcinosarcoma/pathology ; Uterine Neoplasms/surgery ; Uterine Neoplasms/pathology ; Sarcoma
Language	English
Publishing date	2023-02-11
Publishing country	Germany
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	134792-5
ISSN	1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
ISSN (online)	1432-1335
ISSN	0171-5216 ; 0084-5353 ; 0943-9382
DOI	10.1007/s00432-023-04594-5
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Article ; Online: Primary flap closure of perineal defects to avoid empty pelvis syndrome after pelvic exenteration in gynecologic malignancies: An old question to explore a new answer.

Arcieri, M / Restaino, S / Rosati, A / Granese, R / Martinelli, C / Caretto, A A / Cianci, S / Driul, L / Gentileschi, S / Scambia, G / Vizzielli, G / Ercoli, A

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2023 Volume 50, Issue 2, Page(s) 107278

Abstract: Pelvic exenteration (PE) is a radical oncological surgical procedure proposed in patients with recurrent or persistent gynecological cancers. The radical alteration of pelvic anatomy and of pelvic floor integrity can cause major postoperative ... ...

Abstract	Pelvic exenteration (PE) is a radical oncological surgical procedure proposed in patients with recurrent or persistent gynecological cancers. The radical alteration of pelvic anatomy and of pelvic floor integrity can cause major postoperative complications. Fortunately, PE can be combined with reconstructive procedures to decrease complications and functional and support problems of pelvic floor, reducing morbility and mortality and increasing quality of life. Many options for reconstructive surgery have been described, especially a wide spectrum of surgical flaps. Different selection criteria have been proposed to select patients for primary perineal defect flap closure without achieving any strict indication of the best option. The aim of this review is to focus on technical aspects and the advantages and disadvantages of each technique, providing an overview of those most frequently used for the treatment of pelvic floor defects after PE. Flaps based on the deep inferior epigastric artery, especially vertical rectus abdominis musculocutaneous (VRAM) flaps, and gracilis flaps, based on the gracilis muscle, are the most common reconstructive techniques used for pelvic floor and vaginal reconstruction. In our opinion, reconstructive surgery may be considered in case of total PE or type II/III PE and in patients submitted to prior pelvic irradiation. VRAM could be used to close extended defects at the time of PE, while gracilis flaps can be used in case of VRAM complications. Fortunately, numerous choices for reconstructive surgery have been devised. As these techniques continue to evolve, it is advisable to adopt an integrated, multi-disciplinary approach within a tertiary medical center.
MeSH term(s)	Humans ; Female ; Genital Neoplasms, Female/surgery ; Pelvic Exenteration/methods ; Quality of Life ; Pelvis/surgery ; Perineum/surgery ; Myocutaneous Flap/transplantation ; Rectus Abdominis/transplantation ; Retrospective Studies
Language	English
Publishing date	2023-12-18
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2023.107278
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