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  1. Article ; Online: Medical Household Waste as a Potential Environmental Hazard

    Adriana Benítez-Rico / Arizbeth Pérez-Martínez / Bryan Isaac Muñóz-López / Laura Martino-Roaro / Jorge Adan Alegría-Baños / Arely Vergara-Castañeda / Alejandro Islas-García

    International Journal of Environmental Research and Public Health, Vol 20, Iss 5366, p

    An Ecological and Epidemiological Approach

    2023  Volume 5366

    Abstract: Nowadays, the contamination caused by emerging pollutants is a global concern due to the lack of scientific evidence to demonstrate the risk or toxicity to humans due to the presence of pharmaceutical residues in the environment. This study aimed to ... ...

    Abstract Nowadays, the contamination caused by emerging pollutants is a global concern due to the lack of scientific evidence to demonstrate the risk or toxicity to humans due to the presence of pharmaceutical residues in the environment. This study aimed to identify and describe the disposal practices of unused and unwanted medications, as well as to analyze and identify the most frequent drugs determined on water bodies adjacent to the biggest urban population in Mexico. A two-phase study with an epidemiological and an ecological assessment was performed. The epidemiological phase was carried out with a descriptive cross-sectional study among citizens from Mexico City and the metropolitan area using an electronic survey applied to 719 subjects aimed to assess practices in which pharmaceutical products are disposed. The ecological phase included a review of scientific reports. The results show that nearly 83.5% of those surveyed use inappropriate practices for disposal medicines, the main ones are through the municipal dump or directly in the drain. The ecological approach was carried out by a systematic literature review of original reports published between 2013 to 2023; information about the class of drugs, active substance, environmental compartments, location, and concentration was extracted and presented. Fifty-one different types of pharmaceutical residues were detected in wastewater in Mexico City in the last decade. The results of this study can contribute to the application of public policies for waste management authorities to mitigate the socio-environmental risks due to the inappropriate disposal of medicines.
    Keywords medication disposal ; drug disposal ; pharmaceutical residues ; emerging pollutants ; environmental hazard ; water bodies ; Medicine ; R
    Subject code 333
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Personal Motivation and Learning Self-Management in Students as Result of the Transition to Online Courses during COVID-19 Pandemic

    Tomás Eduardo Chávez-Miyauchi / Adriana Benitez-Rico / Manuel Alcántara-Flores / Arely Vergara-Castañeda / Ana Belén Ogando-Justo

    Nova Scientia, Vol 13, Iss e (2021)

    2021  

    Abstract: COVID-19 pandemic has changed the normal course of activities around the World. The measures implemented to slow down the spread of the disease and its impact on the health system have also suggested a change in population dynamics. In the educational ... ...

    Abstract COVID-19 pandemic has changed the normal course of activities around the World. The measures implemented to slow down the spread of the disease and its impact on the health system have also suggested a change in population dynamics. In the educational aspect, the paradigm of the traditional education had to change completely to a remote environment, representing a challenge for students, teachers, and education institutions. In this work we report the students’ response to the actions taken by the faculty of the Chemistry Sciences School of Universidad La Salle México to face online courses ensuring student accompaniment. After the term, a qualitative and quantitative study was performed to the school population using an electronic survey to address the response of students to the applied strategy. Data was analyzed using SPSS® software. 266 responses were obtained, which represents a response rate of 44%. 75.6% of the alumni reported having a good or excellent disposition regarding virtual sessions. Likewise, 48.9% reported adapting appropriately to the remote working modality. Also, 83.5% of students recognize the labor of the teachers by acknowledging that their effort and dedication was excellent or good. Students showed development of soft skills such as self-time and learning management; written, oral and technological communication. These results suggest the advantages perceived by students during the transition to virtual modality, mostly oriented to self-management of their learning and that could conform the basis for the development of new strategies that can be useful not only for a contingency situation, but also in the structuration and innovation of science programs.
    Keywords Chemical Education Research ; Problem-Solving ; Computer-based Learning ; Self Instruction ; COVID-19 ; pandemic ; Science ; Q ; Science (General) ; Q1-390 ; Social Sciences ; H ; Social sciences (General) ; H1-99
    Subject code 370
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Universidad De La Salle Bajío
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: In Silico Study of Polyunsaturated Fatty Acids as Potential SARS-CoV-2 Spike Protein Closed Conformation Stabilizers

    Alonso Vivar-Sierra / María José Araiza-Macías / José Patricio Hernández-Contreras / Arely Vergara-Castañeda / Gabriela Ramírez-Vélez / Rodolfo Pinto-Almazán / Juan Rodrigo Salazar / Marco A. Loza-Mejía

    Molecules, Vol 26, Iss 3, p

    Epidemiological and Computational Approaches

    2021  Volume 711

    Abstract: SARS-CoV-2 infects host cells by interacting its spike protein with surface angiotensin-converting enzyme 2 (ACE2) receptors, expressed in lung and other cell types. Although several risk factors could explain why some countries have lower incidence and ... ...

    Abstract SARS-CoV-2 infects host cells by interacting its spike protein with surface angiotensin-converting enzyme 2 (ACE2) receptors, expressed in lung and other cell types. Although several risk factors could explain why some countries have lower incidence and fatality rates than others, environmental factors such as diet should be considered. It has been described that countries with high polyunsaturated fatty acid (PUFA) intake have a lower number of COVID-19 victims and a higher rate of recovery from the disease. Moreover, it was found that linoleic acid, an omega-6 PUFA, could stabilize the spike protein in a closed conformation, blocking its interaction with ACE2. These facts prompted us to perform in silico simulations to determine if other PUFA could also stabilize the closed conformation of spike protein and potentially lead to a reduction in SARS-CoV-2 infection. We found that: (a) countries whose source of omega-3 is from marine origin have lower fatality rates; and (b) like linoleic acid, omega-3 PUFA could also bind to the closed conformation of spike protein and therefore, could help reduce COVID-19 complications by reducing viral entrance to cells, in addition to their known anti-inflammatory effects.
    Keywords COVID-19 ; SARS-CoV-2 ; PUFA ; molecular docking ; spike protein ; DHA ; Organic chemistry ; QD241-441
    Subject code 612
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico

    Montserrat Elemi García-Hernández / Mayra Cruz-Rivera / José Iván Sánchez-Betancourt / Oscar Rico-Chávez / Arely Vergara-Castañeda / María E. Trujillo / Rosa Elena Sarmiento-Silva

    BMC Veterinary Research, Vol 13, Iss 1, Pp 1-

    2017  Volume 5

    Abstract: Abstract Background Hepatitis E virus (HEV) infection is one of the most common causes of acute liver diseases in humans worldwide. In developing countries, HEV is commonly associated with waterborne outbreaks. Conversely, in industrialized countries, ... ...

    Abstract Abstract Background Hepatitis E virus (HEV) infection is one of the most common causes of acute liver diseases in humans worldwide. In developing countries, HEV is commonly associated with waterborne outbreaks. Conversely, in industrialized countries, HEV infection is often associated with travel to endemic regions or ingestion of contaminated animal products. Limited information on both, human and animal HEV infection in Mexico is available. As a consequence, the distribution of the virus in the country is largely unknown. Here, we assessed the seroprevalence of HEV among swine in different geographical regions in Mexico. Methods Seroprevalence of anti-HEV antibodies in swine herds in Mexico was evaluated in a representative sample including 945 pig serum specimens from different regions of the country using a commercial enzyme-linked immunosorbent assay (ELISA). Results The overall prevalence of anti-HEV antibodies in swine was 59.4%. The northern region of Mexico exhibited the highest seroprevalence in the country (86.6%), while the central and southern regions in Mexico showed lower seroprevalence, 42.7% and 51.5%, respectively. Conclusions In Mexico, HEV seroprevalence in swine is high. Importantly, northern Mexico showed the highest seroprevalence in the country. Thus, further studies are required to identify the risk factors contributing to HEV transmission among pigs in the country. Assessment of HEV human infection in the context of viral transmission in swine is required to better understand the epidemiology of hepatitis E in Mexico.
    Keywords HEV ; Mexico ; Pigs ; Seroprevalence ; Veterinary medicine ; SF600-1100
    Subject code 600
    Language English
    Publishing date 2017-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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