LIVIVO - Search results -

Search results

Result 1 - 10 of total 212

Search options

Book ; Online: Organizações políticas internacionais: os desafios da cooperação internacional: Breve estudo sobre dez organizações internacionais

Arena, Maria do Céu de Pinho Ferreira Pinto

2023

Keywords	International relations ; International institutions ; Organizações Internacionais ; ONU ; Conselho da Europa ; NATO ; Organização sobre a Segurança e Cooperação na Europa ; Comunidade dos Países de Língua Portuguesa ; União Africana ; Organização dos Estados Americanos ; Associação de Nações do Sudeste Asiático (ASEAN) ; Liga Árabe ; Organização de Cooperação de Xangai
Language	Portuguese
Size	1 electronic resource (227 pages)
Publishing place	Braga
Document type	Book ; Online
Note	Portuguese
HBZ-ID	HT030376296
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Fish toxicity testing for identification of thyroid disrupting chemicals.

Dang, ZhiChao / Arena, Maria / Kienzler, Aude

Environmental pollution (Barking, Essex : 1987)

2021 Volume 284, Page(s) 117374

Abstract: Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals, pesticides, and biocides. Following that requirement, the use of fish as ... ...

Abstract	Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals, pesticides, and biocides. Following that requirement, the use of fish as a unique non-mammalian model species for identification of EDs may be warranted. This study summarized and evaluated effects of TDCs on fish thyroid sensitive endpoints including thyroid hormones, thyroid related gene expression, immunostaining for thyroid follicles, eye size and pigmentation, swim bladder inflation as well as effects of TDCs on secondary sex characteristics, sex ratio, growth and reproduction. Changes in thyroid sensitive endpoints may reflect the balanced outcome of different processes of the thyroid cascade. Thyroid sensitive endpoints may also be altered by non-thyroid molecular or endocrine pathways as well as non-specific factors such as general toxicity, development, stress, nutrient, and the environmental factors like temperature and pH. Defining chemical specific effects on thyroid sensitive endpoints is important for identification of TDCs. Application of the AOP (adverse outcome pathway) concept could be helpful for defining critical events needed for testing and identification of TDCs in fish.
MeSH term(s)	Animals ; Endocrine Disruptors/toxicity ; Thyroid Gland ; Toxicity Tests ; Water Pollutants, Chemical/toxicity ; Zebrafish
Chemical Substances	Endocrine Disruptors ; Water Pollutants, Chemical
Language	English
Publishing date	2021-05-18
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2021.117374
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2599: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: COVID-19: The Dysregulated Response to Infection - Why Consider Polymethylmethacrylate Membrane in Hemodialysis Patients?

Spasiano, Andrea / De Luca, Gianmarco / Bartoli, Giulia / Dello Strologo, Andrea / Arena, Maria / Grandaliano, Giuseppe

Blood purification

2023 Volume 53, Issue 5, Page(s) 373–378

Abstract: Since SARS-CoV-2 spread through China at the end of 2019, COVID-19 has been probably the most difficult challenge in the last decades for healthcare systems all around the world, still representing a danger for fragile patients with different ... ...

Abstract	Since SARS-CoV-2 spread through China at the end of 2019, COVID-19 has been probably the most difficult challenge in the last decades for healthcare systems all around the world, still representing a danger for fragile patients with different comorbidities. Chronic dialysis patients affected by COVID-19 experienced severe disease with a higher mortality rate compared to the general population. Morbidity and mortality of this severe acute respiratory syndrome depend on both acute respiratory failure and systemic immunological involvement with consequent inflammation-mediated injury. Indeed, the most important determining factor of COVID-19 severity is the strength of the so-called "cytokine storm" associated with SARS-CoV-2 infection. Therefore, this severe infection varies clinically from an asymptomatic condition to a generalized and violent inflammatory response and acute respiratory distress syndrome, with consequent pulmonary interstitial edema and a high risk of multi-organ failure. The use of extracorporeal therapies targeting cytokine clearance to improve patients' outcomes has been widely debated, especially in end-stage kidney disease's patients on maintenance dialysis or in individuals affected by acute kidney injury admitted to intensive care units. Different studies were conducted to demonstrate how specific dialyzers could decrease the COVID-19 inflammatory state. The aim of this narrative review was to summarize main studies about this topic, focusing primarily on the role of polymethylmethacrylate dialyzer and underlining pros and cons of this sorbent.
MeSH term(s)	Humans ; COVID-19/complications ; COVID-19/therapy ; SARS-CoV-2 ; Polymethyl Methacrylate ; Renal Dialysis ; Cytokines ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy
Chemical Substances	Polymethyl Methacrylate (9011-14-7) ; Cytokines
Language	English
Publishing date	2023-10-16
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	605548-5
ISSN	1421-9735 ; 0253-5068
ISSN (online)	1421-9735
ISSN	0253-5068
DOI	10.1159/000533738
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1872: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Fish toxicity testing for identification of thyroid disrupting chemicals

Dang, ZhiChao / Arena, Maria / Kienzler, Aude

Environmental pollution. 2021 Sept. 01, v. 284

2021

Abstract	Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals, pesticides, and biocides. Following that requirement, the use of fish as a unique non-mammalian model species for identification of EDs may be warranted. This study summarized and evaluated effects of TDCs on fish thyroid sensitive endpoints including thyroid hormones, thyroid related gene expression, immunostaining for thyroid follicles, eye size and pigmentation, swim bladder inflation as well as effects of TDCs on secondary sex characteristics, sex ratio, growth and reproduction. Changes in thyroid sensitive endpoints may reflect the balanced outcome of different processes of the thyroid cascade. Thyroid sensitive endpoints may also be altered by non-thyroid molecular or endocrine pathways as well as non-specific factors such as general toxicity, development, stress, nutrient, and the environmental factors like temperature and pH. Defining chemical specific effects on thyroid sensitive endpoints is important for identification of TDCs. Application of the AOP (adverse outcome pathway) concept could be helpful for defining critical events needed for testing and identification of TDCs in fish.
Keywords	adverse outcome pathways ; biocides ; eyes ; fish ; gene expression ; pH ; pigmentation ; pollution ; reproduction ; sex ratio ; swim bladder ; temperature ; toxicity
Language	English
Dates of publication	2021-0901
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2021.117374
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 4136: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: The Role of Diet in Bone and Mineral Metabolism and Secondary Hyperparathyroidism

Bargagli, Matteo / Arena, Maria / Naticchia, Alessandro / Gambaro, Giovanni / Mazzaferro, Sandro / Fuster, Daniel / Ferraro, Pietro Manuel

Nutrients. 2021 July 07, v. 13, no. 7

2021

Abstract: Bone disorders are a common complication of chronic kidney disease (CKD), obesity and gut malabsorption. Secondary hyperparathyroidism (SHPT) is defined as an appropriate increase in parathyroid hormone (PTH) secretion, driven by either reduced serum ... ...

Abstract	Bone disorders are a common complication of chronic kidney disease (CKD), obesity and gut malabsorption. Secondary hyperparathyroidism (SHPT) is defined as an appropriate increase in parathyroid hormone (PTH) secretion, driven by either reduced serum calcium or increased phosphate concentrations, due to an underlying condition. The available evidence on the effects of dietary advice on secondary hyperparathyroidism confirms the benefit of a diet characterized by decreased phosphate intake, avoiding low calcium and vitamin D consumption (recommended intakes 1000–1200 mg/day and 400–800 UI/day, respectively). In addition, low protein intake in CKD patients is associated with a better control of SHPT risk factors, although its strength in avoiding hyperphosphatemia and the resulting outcomes are debated, mostly for dialyzed patients. Ultimately, a consensus on the effect of dietary acid loads in the prevention of SHPT is still lacking. In conclusion, a reasonable approach for reducing the risk for secondary hyperparathyroidism is to individualize dietary manipulation based on existing risk factors and concomitant medical conditions. More studies are needed to evaluate long-term outcomes of a balanced diet on the management and prevention of secondary hyperparathyroidism in at-risk patients at.
Keywords	blood serum ; calcium ; diet ; digestive system ; hyperparathyroidism ; kidney diseases ; malabsorption ; mineral metabolism ; obesity ; parathyroid hormone ; phosphates ; protein intake ; secretion
Language	English
Dates of publication	2021-0707
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13072328
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: A meta-analysis comparing the sensitivity of bees to pesticides.

Arena, Maria / Sgolastra, Fabio

Ecotoxicology (London, England)

2014 Volume 23, Issue 3, Page(s) 324–334

Abstract: The honey bee Apis mellifera, the test species used in the current environmental risk assessment procedure, is generally considered as extremely sensitive to pesticides when compared to other bee species, although a quantitative approach for comparing ... ...

Abstract	The honey bee Apis mellifera, the test species used in the current environmental risk assessment procedure, is generally considered as extremely sensitive to pesticides when compared to other bee species, although a quantitative approach for comparing the difference in sensitivity among bees has not yet been reported. A systematic review of the relevant literature on the topic followed by a meta-analysis has been performed. Both the contact and oral acute LD50 and the chronic LC50 reported in laboratory studies for as many substances as possible have been extracted from the papers in order to compare the sensitivity to pesticides of honey bees and other bee species (Apiformes). The sensitivity ratio R between the endpoint for the species a (A. mellifera) and the species s (bees other than A. mellifera) was calculated for a total of 150 case studies including 19 bee species. A ratio higher than 1 indicated that the species s was more sensitive to pesticides than honey bees. The meta-analysis showed a high variability of sensitivity among bee species (R from 0.001 to 2085.7), however, in approximately 95 % of the cases the sensitivity ratio was below 10. The effect of pesticides in domestic and wild bees is dependent on the intrinsic sensitivity of single bee species as well as their specific life cycle, nesting activity and foraging behaviour. Current data indicates a need for more comparative information between honey bees and non-Apis bees as well as separate pesticide risk assessment procedures for non-Apis bees.
MeSH term(s)	Administration, Oral ; Animals ; Bees/drug effects ; Lethal Dose 50 ; Pesticides/toxicity ; Risk Assessment ; Toxicity Tests, Chronic
Chemical Substances	Pesticides
Language	English
Publishing date	2014-01-17
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	34042-x
ISSN	1573-3017 ; 0963-9292
ISSN (online)	1573-3017
ISSN	0963-9292
DOI	10.1007/s10646-014-1190-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 7663: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article: A meta-analysis comparing the sensitivity of bees to pesticides

Arena, Maria / Sgolastra, Fabio

Ecotoxicology. 2014 Apr., v. 23, no. 3

2014

Abstract	The honey bee Apis mellifera, the test species used in the current environmental risk assessment procedure, is generally considered as extremely sensitive to pesticides when compared to other bee species, although a quantitative approach for comparing the difference in sensitivity among bees has not yet been reported. A systematic review of the relevant literature on the topic followed by a meta-analysis has been performed. Both the contact and oral acute LD₅₀ and the chronic LC₅₀ reported in laboratory studies for as many substances as possible have been extracted from the papers in order to compare the sensitivity to pesticides of honey bees and other bee species (Apiformes). The sensitivity ratio R between the endpoint for the species a (A. mellifera) and the species s (bees other than A. mellifera) was calculated for a total of 150 case studies including 19 bee species. A ratio higher than 1 indicated that the species s was more sensitive to pesticides than honey bees. The meta-analysis showed a high variability of sensitivity among bee species (R from 0.001 to 2085.7), however, in approximately 95� % of the cases the sensitivity ratio was below 10. The effect of pesticides in domestic and wild bees is dependent on the intrinsic sensitivity of single bee species as well as their specific life cycle, nesting activity and foraging behaviour. Current data indicates a need for more comparative information between honey bees and non-Apis bees as well as separate pesticide risk assessment procedures for non-Apis bees.
Keywords	Apis mellifera ; case studies ; foraging ; honey bees ; lethal concentration 50 ; lethal dose 50 ; meta-analysis ; nesting ; pesticides ; risk assessment ; systematic review
Language	English
Dates of publication	2014-04
Size	p. 324-334.
Publishing place	Springer-Verlag
Document type	Article
ZDB-ID	34042-x
ISSN	1573-3017 ; 0963-9292
ISSN (online)	1573-3017
ISSN	0963-9292
DOI	10.1007/s10646-014-1190-1
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 7663: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Fatigue in Kidney Transplantation: A Systematic Review and Meta-Analysis.

Bossola, Maurizio / Arena, Maria / Urciuolo, Federica / Antocicco, Manuela / Pepe, Gilda / Calabrò, Giovanna Elisa / Cianfrocca, Claudia / Stasio, Enrico Di

Diagnostics (Basel, Switzerland)

2021 Volume 11, Issue 5

Abstract: Fatigue is still present in up to 40-50% of kidney transplant recipients (KTR), the results of studies comparing the prevalence among patients on hemodialysis (HD) and KTR led to conflicting results. Fatigue correlates include inflammation, symptoms of ... ...

Abstract	Fatigue is still present in up to 40-50% of kidney transplant recipients (KTR), the results of studies comparing the prevalence among patients on hemodialysis (HD) and KTR led to conflicting results. Fatigue correlates include inflammation, symptoms of depression, sleep disorders and obesity. Fatigue in KTR leads to significant functional impairment, it is common among KTR poorly adherent to immunosuppressive therapy and is associated with a serious deterioration of quality of life. The following databases were searched for relevant studies up to November 2020: Medline, PubMed, Web of Science and the Cochrane Library. Several studies have compared the prevalence and severity of fatigue between KTR and hemodialysis or healthy patients. They have shown that fatigue determines a significant functional deterioration with less chance of having a paid job and a significant change in quality of life. The aim of the review is to report methods to assess fatigue and its prevalence in KTR patients, compared to HD subjects and define the effects of fatigue on health status and daily life. There is no evidence of studies on the treatment of this symptom in KTR. Efforts to identify and treat fatigue should be a priority to improve the quality of life of KTR.
Language	English
Publishing date	2021-05-05
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics11050833
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The Role of Diet in Bone and Mineral Metabolism and Secondary Hyperparathyroidism.

Bargagli, Matteo / Arena, Maria / Naticchia, Alessandro / Gambaro, Giovanni / Mazzaferro, Sandro / Fuster, Daniel / Ferraro, Pietro Manuel

Nutrients

2021 Volume 13, Issue 7

Abstract	Bone disorders are a common complication of chronic kidney disease (CKD), obesity and gut malabsorption. Secondary hyperparathyroidism (SHPT) is defined as an appropriate increase in parathyroid hormone (PTH) secretion, driven by either reduced serum calcium or increased phosphate concentrations, due to an underlying condition. The available evidence on the effects of dietary advice on secondary hyperparathyroidism confirms the benefit of a diet characterized by decreased phosphate intake, avoiding low calcium and vitamin D consumption (recommended intakes 1000-1200 mg/day and 400-800 UI/day, respectively). In addition, low protein intake in CKD patients is associated with a better control of SHPT risk factors, although its strength in avoiding hyperphosphatemia and the resulting outcomes are debated, mostly for dialyzed patients. Ultimately, a consensus on the effect of dietary acid loads in the prevention of SHPT is still lacking. In conclusion, a reasonable approach for reducing the risk for secondary hyperparathyroidism is to individualize dietary manipulation based on existing risk factors and concomitant medical conditions. More studies are needed to evaluate long-term outcomes of a balanced diet on the management and prevention of secondary hyperparathyroidism in at-risk patients at.
MeSH term(s)	Bone and Bones/physiopathology ; Calcium/blood ; Diet/adverse effects ; Diet/methods ; Eating/physiology ; Humans ; Hyperparathyroidism, Secondary/etiology ; Hyperparathyroidism, Secondary/physiopathology ; Hyperparathyroidism, Secondary/prevention & control ; Minerals/blood ; Nutritional Physiological Phenomena/physiology ; Parathyroid Hormone/blood ; Phosphates/blood ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diet therapy ; Risk Factors ; Vitamin D/blood
Chemical Substances	Minerals ; Parathyroid Hormone ; Phosphates ; Vitamin D (1406-16-2) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2021-07-07
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13072328
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Book: Federico II

Arena, Maria Paola

enciclopedia fridericiana

2005

Author's details	[Red.: Maria Paola Arena ...]
Language	Italian
Publisher	Istituto della Enciclopedia Italiana
Publishing place	Roma
Document type	Book
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Inter-library loan at ZB MED