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  1. Book: Atlas of microkeratome assisted lamellar keratoplasty

    Busin, Massimo / Arffa, Robert C.

    2006  

    Author's details Massimo Busin ; Robert C. Arffa
    Keywords Corneal Transplantation ; Corneal Diseases / surgery ; Refractive Errors / surgery ; Keratomileusis, Laser In Situ / methods
    Language English
    Size XI, 116 S. : zahlr. Ill.
    Publisher Slack
    Publishing place Thorofare, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT014790855
    ISBN 1-55642-742-5 ; 978-1-55642-742-8
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Grayson's diseases of the cornea

    Arffa, Robert C. / Grayson, Merrill

    1991  

    Author's details Robert C. Arffa
    Keywords Corneal Diseases ; Hornhautkrankheit
    Subject Korneakrankheit
    Size XIII, 725 S. : zahlr. Ill., graph. Darst.
    Edition 3. ed.
    Publisher Mosby
    Publishing place St. Louis u.a.
    Publishing country United States
    Document type Book
    Old title 2. Aufl. u.d.T. Grayson, Merrill: Diseases on the cornea
    HBZ-ID HT003935312
    ISBN 0-8016-0262-9 ; 978-0-8016-0262-7
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Atlas of microkeratome assisted lamellar keratoplasty

    Busin, Massimo / Arffa, Robert C

    2006  

    Title variant Microkeratome assisted lamellar keratoplasty
    Author's details Massimo Busin, Robert C. Arffa
    MeSH term(s) Corneal Transplantation ; Corneal Diseases/surgery ; Keratomileusis, Laser In Situ/methods ; Refractive Surgical Procedures
    Language English
    Size xi, 116 p. :, ill.
    Publisher SLACK Inc
    Publishing place Thorofare, NJ
    Document type Book
    ISBN 9781556427428 ; 1556427425
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article: Microkeratome-assisted mushroom keratoplasty with minimal endothelial replacement.

    Busin, Massimo / Arffa, Robert C

    American journal of ophthalmology

    2005  Volume 140, Issue 1, Page(s) 138–140

    Abstract: Purpose: To report the outcome of a new keratoplasty technique aimed at treating full-thickness opacities with minimal removal of recipient endothelium.: Design: Interventional case report.: Methods: A deep central scar was removed using ... ...

    Abstract Purpose: To report the outcome of a new keratoplasty technique aimed at treating full-thickness opacities with minimal removal of recipient endothelium.
    Design: Interventional case report.
    Methods: A deep central scar was removed using microkeratome-assisted mushroom-shaped keratoplasty, consisting of a large anterior stromal lamella (9.0-mm in diameter) and a small posterior button (5.0-mm in diameter) including deep stroma and endothelium. Complete suture removal was performed 3 months after surgery. Visual acuity, refraction, and computerized corneal topography were evaluated pre- and postoperatively.
    Results: Best spectacle-corrected visual acuity improved from 20/60 to 20/20 at 6 months postoperatively. Postoperative refraction was -2.50-1.00 x 20 degrees.
    Conclusions: Microkeratome-assisted mushroom keratoplasty may offer visual and refractive advantages over conventional keratoplasty surgery. Because most of the recipient endothelium is preserved and may spread onto the posterior surface of the small donor button, graft decompensation secondary to immunologic rejection may be avoided with this technique.
    MeSH term(s) Adult ; Corneal Opacity/diagnosis ; Corneal Opacity/surgery ; Corneal Stroma/pathology ; Corneal Stroma/surgery ; Endothelium, Corneal/pathology ; Endothelium, Corneal/surgery ; Humans ; Keratoplasty, Penetrating/methods ; Male ; Visual Acuity
    Language English
    Publishing date 2005-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2004.12.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Deep suturing technique for penetrating keratoplasty.

    Busin, Massimo / Arffa, Robert C

    Cornea

    2002  Volume 21, Issue 7, Page(s) 680–684

    Abstract: Purpose: To evaluate the effect of a new suturing technique on postkeratoplasty visual rehabilitation time and refractive error.: Methods: Penetrating keratoplasty was performed on 17 eyes with keratoconus using a modified suturing technique. A donor ...

    Abstract Purpose: To evaluate the effect of a new suturing technique on postkeratoplasty visual rehabilitation time and refractive error.
    Methods: Penetrating keratoplasty was performed on 17 eyes with keratoconus using a modified suturing technique. A donor button 8.0 mm in diameter was sutured into a 7.75-mm recipient bed with both deep and superficial sutures. The deep sutures consisted of either a single 16-bite 10-0 nylon running suture (n = 7) or eight interrupted 10-0 nylon cross-stitches (n = 10). These sutures were passed into the mid-stroma of the donor cornea and exited through the donor endothelium, then passed through the endothelium of the recipient cornea and exited from its mid-stroma. Thereby all parts of the deep sutures remained below the corneal surface. To further secure the surgical wound, in each case a running 16-bite 10-0 nylon superficial suture was also placed. Care was taken to maintain the bites of the superficial suture above the level of the deep sutures. The superficial suture was removed 3 months after surgery. Vision and refraction were recorded 1 day and 1 month postoperatively and 1 and 3 months after suture removal. A paired Student test was used to verify the significance of changes in visual acuity and refraction recorded at different examination times.
    Results: As early as 1 month after surgery, spectacle best-corrected visual acuity 20/40 or more and refractive astigmatism less than 4 diopters (D) were recorded in each eye and maintained with two exceptions at the later examination times. In two patients, postoperative astigmatism increased from 4.5 to 5 D after suture removal.
    Conclusions: Deep suturing allowed quick visual rehabilitation while minimizing postkeratoplasty astigmatism in the patients with keratoconus operated on in this series.
    MeSH term(s) Adult ; Astigmatism/etiology ; Astigmatism/physiopathology ; Cornea/pathology ; Corneal Topography ; Eyeglasses ; Female ; Humans ; Keratoconus/pathology ; Keratoconus/physiopathology ; Keratoconus/surgery ; Keratoplasty, Penetrating/adverse effects ; Male ; Middle Aged ; Suture Techniques ; Time Factors ; Visual Acuity
    Language English
    Publishing date 2002-07-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/00003226-200210000-00009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Microkeratome-assisted lamellar keratoplasty for the surgical treatment of keratoconus.

    Busin, Massimo / Zambianchi, Luca / Arffa, Robert C

    Ophthalmology

    2005  Volume 112, Issue 6, Page(s) 987–997

    Abstract: Purpose: To evaluate the visual and refractive results of microkeratome-assisted lamellar keratoplasty (LK) performed on keratoconus patients intolerant to spectacles and contact lenses.: Design: Prospective, noncomparative, interventional study.: ... ...

    Abstract Purpose: To evaluate the visual and refractive results of microkeratome-assisted lamellar keratoplasty (LK) performed on keratoconus patients intolerant to spectacles and contact lenses.
    Design: Prospective, noncomparative, interventional study.
    Participants: A microkeratome-assisted LK procedure was performed on 50 eyes of 50 keratoconus patients. All patients were spectacle and contact lens intolerant.
    Intervention: All patients included in this study underwent a standard surgical procedure involving removal of a lamella (9 mm in diameter cut with the 250-microm microkeratome head) from the recipient cornea by means of a hand-driven microkeratome and suturing of a donor lamella (0.5 mm smaller in diameter than the removed corneal lamella, cut with the 350-microm microkeratome head) obtained from a cornea mounted on an artificial anterior chamber. Each patient was examined preoperatively and at different postoperative times (1 and 6 months and 1, 2, 3, and 4 years).
    Main outcome measures: Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), 1-year best contact lens-corrected visual acuity (BCLCVA), refraction, and computerized analysis of corneal topography.
    Results: After suture removal was completed, both UCVA and best-corrected visual acuity were significantly improved over properative values at all examination times. One year postoperatively, when follow-up was still available for all patients, UCVA was better than 20/200 in 8 of 50 (16%) patients and BSCVA was > or =20/40 in 44 of 50 (88%) patients, whereas BCLCVA was > or =20/40 in all 50 patients. Refractive astigmatism within 4 diopters was seen in 43 of 50 (86%) patients. Corneal topographic patterns were classified as regularly astigmatic in 39 of 50 (78%) patients. The 1-year values did not change substantially at later postoperative examination times. Complications included preparation of donor grafts of poor quality that needed to be discarded (8 cases [16%]), irregular astigmatism of various degrees (11 cases [22%]), high-degree astigmatism requiring secondary intervention (6 cases [12%]), epithelial interface ingrowth (1 case [2%]), and cataract formation (1 case [2%]).
    Conclusions: Microkeratome-assisted LK can be performed on corneas with moderate to advanced keratoconus with a minimal corneal thickness of >380 microm. The procedure is relatively simple, may be standardized in most of its parts, and does not involve time-consuming maneuvers. All complications recorded did not threaten vision and were dealt with successfully. Our results indicate that microkeratome-assisted LK is as efficacious as conventional penetrating keratoplasty for the surgical treatment of keratoconus. However, the time necessary to achieve stable results is considerably shorter.
    MeSH term(s) Adult ; Aged ; Cornea/physiopathology ; Cornea/surgery ; Corneal Topography ; Corneal Transplantation/instrumentation ; Corneal Transplantation/methods ; Female ; Follow-Up Studies ; Humans ; Intraoperative Complications ; Keratoconus/physiopathology ; Keratoconus/surgery ; Male ; Middle Aged ; Postoperative Complications ; Prospective Studies ; Refraction, Ocular/physiology ; Visual Acuity/physiology
    Language English
    Publishing date 2005-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2005.01.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mycobacterium chelonae interface infection after endokeratoplasty.

    Busin, Massimo / Ponzin, Diego / Arffa, Robert C

    American journal of ophthalmology

    2003  Volume 135, Issue 3, Page(s) 393–395

    Abstract: Purpose: To report a case of interface infection by Mycobacterium chelonae in a patient who underwent endokeratoplasty.: Design: Interventional case report.: Setting: Clinical practice.: Methods: Two weeks after endokeratoplasty, a 74-year-old ... ...

    Abstract Purpose: To report a case of interface infection by Mycobacterium chelonae in a patient who underwent endokeratoplasty.
    Design: Interventional case report.
    Setting: Clinical practice.
    Methods: Two weeks after endokeratoplasty, a 74-year-old woman developed multiple enlarging interface infiltrates in her right eye. Cultures performed on the preservation medium grew Mycobacterium chelonae. Penetrating keratoplasty (PK) surgery was performed after failure of conservative antibiotic therapy, including topical and systemic clarithromycin.
    Results: Five months after PK surgery, the graft was clear and no signs of extraocular or intraocular inflammation were present. Cultures taken from the corneal interface at the time of PK surgery confirmed the presence of M. chelonae. Acid-fast bacilli were seen in the excised corneal button.
    Conclusions: M. chelonae should be ruled out as a possible etiologic agent when postoperative infection of the corneal interface occurs. Surgical intervention can lead to eradication of the infection when conservative treatment fails.
    MeSH term(s) Aged ; Corneal Diseases/diagnosis ; Corneal Diseases/microbiology ; Corneal Diseases/surgery ; Corneal Transplantation/adverse effects ; Eye Infections, Bacterial/diagnosis ; Eye Infections, Bacterial/etiology ; Eye Infections, Bacterial/surgery ; Female ; Humans ; Keratoplasty, Penetrating ; Mycobacterium Infections, Nontuberculous/diagnosis ; Mycobacterium Infections, Nontuberculous/etiology ; Mycobacterium Infections, Nontuberculous/surgery ; Mycobacterium chelonae/isolation & purification ; Surgical Flaps/microbiology ; Surgical Wound Infection/diagnosis ; Surgical Wound Infection/microbiology ; Surgical Wound Infection/surgery
    Language English
    Publishing date 2003-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/s0002-9394(02)01954-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Grayson's diseases of the cornea

    Arffa, Robert C / Grayson, Merrill

    1997  

    Title variant Diseases of the cornea
    MeSH term(s) Corneal Diseases
    Language English
    Size xii, 765 p. :, ill.
    Edition 4th ed. /
    Publisher Mosby
    Publishing place St. Louis
    Document type Book
    ISBN 9780815136545 ; 0815136544
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Book: Grayson's diseases of the cornea

    Arffa, Robert C / Grayson, Merrill

    1991  

    Title variant Diseases of the cornea
    MeSH term(s) Corneal Diseases
    Language English
    Size xiii, 725 p. :, ill.
    Edition 3rd ed. /
    Publisher Mosby Year Book
    Publishing place St. Louis
    Document type Book
    Note Rev. ed. of: Diseases of the cornea / Merrill Grayson. 2nd ed. 1983.
    ISBN 9780801602627 ; 0801602629
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Book: Grayson's diseases of the cornea

    Arffa, Robert C / Grayson, Merrill

    1991  

    Author's details Robert C. Arffa
    MeSH term(s) Corneal Diseases
    Keywords Cornea/Diseases
    Language English
    Size XIII, 725 S, zahlr. Ill
    Edition 3. ed
    Publisher Mosby
    Publishing place St. Louis u.a.
    Document type Book
    Note 2. Aufl. u. d. T.: Diseases of the cornea / Merrill Grayson
    ISBN 0801602629 ; 9780801602627
    Database Former special subject collection: coastal and deep sea fishing

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