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Article: Imaging of Peritoneal Metastases in Ovarian Cancer Using MDCT, MRI, and FDG PET/CT: A Systematic Review and Meta-Analysis.

Tsili, Athina C / Alexiou, George / Tzoumpa, Martha / Siempis, Timoleon / Argyropoulou, Maria I

2024 Volume 16, Issue 8

Abstract: This review aims to compare the diagnostic performance of multidetector CT (MDCT), MRI, including diffusion-weighted imaging, and FDG PET/CT in the detection of peritoneal metastases (PMs) in ovarian cancer (OC). A comprehensive search was performed for ... ...

Abstract	This review aims to compare the diagnostic performance of multidetector CT (MDCT), MRI, including diffusion-weighted imaging, and FDG PET/CT in the detection of peritoneal metastases (PMs) in ovarian cancer (OC). A comprehensive search was performed for articles published from 2000 to February 2023. The inclusion criteria were the following: diagnosis/suspicion of PMs in patients with ovarian/fallopian/primary peritoneal cancer; initial staging or suspicion of recurrence; MDCT, MRI and/or FDG PET/CT performed for the detection of PMs; population of at least 10 patients; surgical results, histopathologic analysis, and/or radiologic follow-up, used as reference standard; and per-patient and per-region data and data for calculating sensitivity and specificity reported. In total, 33 studies were assessed, including 487 women with OC and PMs. On a per-patient basis, MRI (
Language	English
Publishing date	2024-04-11
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers16081467
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Article ; Online: "Long-term MRI findings in Ankylosing spondylitis patients treated with TNF inhibitors for a decade".

Venetsanopoulou, Aliki I / Anagnostou, Nikoletta E / Tziortzioti, Zoi / Zikou, Anastasia / Astrakas, Loukas / Argyropoulou, Maria I / Voulgari, Paraskevi V

Rheumatology international

2024

Abstract: Objective: This study aims to evaluate the active and chronic lesions in sacroiliac joints and lumbar spine over a decade of TNFi therapy in patients with AS.: Methods: The study enrolled patients with AS under treatment with a TNFi for over a decade. ...

Abstract	Objective: This study aims to evaluate the active and chronic lesions in sacroiliac joints and lumbar spine over a decade of TNFi therapy in patients with AS. Methods: The study enrolled patients with AS under treatment with a TNFi for over a decade. The patients underwent a new MRI scan of their lumbar spine and sacroiliac joint (SIJ). Two readers evaluated all images. Inflammation of SIJ (SIS), SIJ structural damage (SSS) including Fat Metaplasia, Erosions, Backfill and Ankylosis, and Spondyloarthritis Research Consortium of Canada Bone marrow edema (SPARCC) spine score were recorded. Results: In the study, 15 patients were included, with 80% being male. The mean age during their first MRI was 38.1 (± 11.9) years old, and the majority (86.7%) tested positive for HLA-B27. While TNFi improved both BASDAI and BASFI scores, there was a noticeable increase in MRI acute lesions in the SIJ over time, where the median score increased from 0 (0-4) to 3 (0-10) after ten years (p = 0.028). After a decade of treatment, the median SPARCC spine score also increased from 0 (0-9) to 5 (0-16), p = 0.093. Finally, it was observed that there was a significant positive correlation between ESR and SIS erosions in cases of chronic lesions (r = 0.819, p < 0.001). Conclusions: While TNFi have significantly improved the treatment of AS, this study shows that acute lesions can still develop despite treatment. A personalized approach that adapts MRI assessment to each patient's specific requirements may help detect changes early and enable doctors to intervene promptly to prevent further damage.
Language	English
Publishing date	2024-01-31
Publishing country	Germany
Document type	Journal Article
ZDB-ID	8286-7
ISSN	1437-160X ; 0172-8172
ISSN (online)	1437-160X
ISSN	0172-8172
DOI	10.1007/s00296-023-05530-z
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Zs.A 1639: Show issues

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Article ; Online: Pituitary gland height evaluated with magnetic resonance imaging in premature twins: the impact of growth and sex.

Argyropoulou, Maria I / Xydis, Vasileios / Astrakas, Loukas G / Drougia, Aikaterini / Styliara, Effrosyni I / Kiortsis, Dimitrios-Nikiforos / Giapros, Vasileios / Kanaka-Gantenbein, Christina

Pediatric radiology

2024 Volume 54, Issue 5, Page(s) 787–794

Abstract: Background: Pituitary gland height reflects secretory activity of the hypothalamo-pituitary axis.: Objective: To assess the cumulative impact of fetal growth and sex on pituitary gland height in premature twins, dissociated from prematurity.: ... ...

Abstract	Background: Pituitary gland height reflects secretory activity of the hypothalamo-pituitary axis. Objective: To assess the cumulative impact of fetal growth and sex on pituitary gland height in premature twins, dissociated from prematurity. Materials and methods: A retrospective study was conducted, assessing the pituitary gland height in 63 pairs of preterm twins, measured from T1-weighted magnetic resonance imaging (MRI). Auxological parameters, including body weight, body length, and head circumference, at birth and at the time of MRI, were used as proxies for fetal and postnatal growth, respectively. The study population was divided into two groups, using corrected age at around term equivalent as the cutoff point. Statistical analysis was performed using mixed-effects linear regression models. Results: When pituitary gland height was evaluated at around term equivalent, a greater pituitary gland height, suggesting a more immature hypothamo-pituitary axis, was associated with the twin exhibiting lower auxological data at birth. The same association was observed when body weight and length at MRI were used as covariants. In the group evaluated after term equivalent, a smaller pituitary gland height, suggesting a more mature hypothamo-pituitary axis, was associated with male sex. This difference was observed in twin pairs with higher average body weight at birth, and in babies exhibiting higher auxological data at MRI. Conclusion: After isolating the effect of prematurity, at around term equivalent, pituitary gland height reflects the cumulative impact of fetal growth on the hypothalamo-pituitary axis. Subsequently, pituitary gland height shows effects of sex and of fetal and postnatal growth.
MeSH term(s)	Humans ; Male ; Female ; Magnetic Resonance Imaging/methods ; Infant, Newborn ; Pituitary Gland/diagnostic imaging ; Pituitary Gland/growth & development ; Infant, Premature/growth & development ; Retrospective Studies ; Sex Factors ; Twins ; Organ Size
Language	English
Publishing date	2024-02-22
Publishing country	Germany
Document type	Journal Article ; Twin Study
ZDB-ID	124459-0
ISSN	1432-1998 ; 0301-0449
ISSN (online)	1432-1998
ISSN	0301-0449
DOI	10.1007/s00247-024-05873-0
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Zs.A 927: Show issues

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Article ; Online: Survival Outcome Prediction in Glioblastoma: Insights from MRI Radiomics.

Styliara, Effrosyni I / Astrakas, Loukas G / Alexiou, George / Xydis, Vasileios G / Zikou, Anastasia / Kafritsas, Georgios / Voulgaris, Spyridon / Argyropoulou, Maria I

Current oncology (Toronto, Ont.)

2024 Volume 31, Issue 4, Page(s) 2233–2243

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Humans ; Glioblastoma/diagnostic imaging ; Glioblastoma/mortality ; Female ; Middle Aged ; Magnetic Resonance Imaging/methods ; Male ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/mortality ; Aged ; Adult ; Survival Analysis ; Prognosis ; Radiomics
Language	English
Publishing date	2024-04-14
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1236972-x
ISSN	1718-7729 ; 1198-0052
ISSN (online)	1718-7729
ISSN	1198-0052
DOI	10.3390/curroncol31040165
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Zs.A 4305: Show issues

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Article ; Online: CT of the urinary tract revisited.

Tsili, Athina C / Varkarakis, Ioannis / Pasoglou, Vassiliki / Anagnostou, Nikoletta / Argyropoulou, Maria I

European journal of radiology

2023 Volume 160, Page(s) 110717

Abstract: Computed tomography (CT) of the abdomen is usually appropriate for the initial imaging of many urinary tract diseases, due to its wide availability, fast scanning and acquisition of thin slices and isotropic data, that allow the creation of multiplanar ... ...

Abstract	Computed tomography (CT) of the abdomen is usually appropriate for the initial imaging of many urinary tract diseases, due to its wide availability, fast scanning and acquisition of thin slices and isotropic data, that allow the creation of multiplanar reformatted and three-dimensional reconstructed images of excellent anatomic details. Non-enhanced CT remains the standard imaging modality for assessing renal colic. The technique allows the detection of nearly all types of urinary calculi and the estimation of stone burden. CT is the primary diagnostic tool for the characterization of an indeterminate renal mass, including both cystic and solid tumors. It is also the modality of choice for staging a primary renal tumor. Urolithiasis and urinary tract malignancies represent the main urogenic causes of hematuria. CT urography (CTU) improves the visualization of both the upper and lower urinary tract and is recommended for the investigation of gross hematuria and microscopic hematuria, in patients with predisposing factors for urologic malignancies. CTU is highly accurate in the detection and staging of upper tract urothelial malignancies. CT represents the most commonly used technique for the detection and staging of bladder carcinoma and the diagnostic efficacy of CT staging improves with more advanced disease. Nevertheless, it has limited accuracy in differentiating non-muscle invasive bladder carcinoma from muscle-invasive bladder carcinoma. In this review, clinical indications and the optimal imaging technique for CT of the urinary tract is reviewed. The CT features of common urologic diseases, including ureterolithiasis, renal tumors and urothelial carcinomas are discussed.
MeSH term(s)	Humans ; Hematuria/diagnostic imaging ; Hematuria/etiology ; Urinary Tract/diagnostic imaging ; Tomography, X-Ray Computed/methods ; Urinary Bladder Neoplasms ; Urologic Neoplasms/diagnostic imaging ; Carcinoma, Transitional Cell ; Urography/methods ; Urologic Diseases/diagnostic imaging ; Kidney Neoplasms/diagnostic imaging
Language	English
Publishing date	2023-01-30
Publishing country	Ireland
Document type	Journal Article ; Review
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2023.110717
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Zs.A 1630: Show issues

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Article ; Online: Multidetector computed tomography in diagnosing peritoneal metastases in ovarian carcinoma.

Tsili, Athina C / Naka, Christina / Argyropoulou, Maria I

Acta radiologica (Stockholm, Sweden : 1987)

2020 Volume 62, Issue 12, Page(s) 1696–1706

Abstract: Multidetector computed tomography (MDCT) of the abdomen is currently the imaging examination of choice for the staging and follow-up of ovarian carcinoma (OC). Peritoneal metastases (PMs) represent the most common pathway for the metastatic spread of OC. ...

Abstract	Multidetector computed tomography (MDCT) of the abdomen is currently the imaging examination of choice for the staging and follow-up of ovarian carcinoma (OC). Peritoneal metastases (PMs) represent the most common pathway for the metastatic spread of OC. MDCT scanners, due to several advantages-including increased volume coverage, reduced scanning time, acquisition of thin slices and creation of multiplanar reformations, and three-dimensional reconstructions-provide useful information regarding the early and accurate detection of PMs. Detailed mapping of peritoneal carcinomatosis is feasible, with improved detection of sub-centimeter peritoneal implants and thorough evaluation of curved peritoneal surfaces.
MeSH term(s)	Carcinoma/diagnostic imaging ; Carcinoma/secondary ; Contrast Media ; Female ; Humans ; Magnetic Resonance Imaging ; Multidetector Computed Tomography ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/pathology ; Peritoneal Neoplasms/diagnostic imaging ; Peritoneal Neoplasms/secondary ; Positron Emission Tomography Computed Tomography ; Sensitivity and Specificity
Chemical Substances	Contrast Media
Language	English
Publishing date	2020-12-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/0284185120980006
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Ue I Zs.105: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 204: Show issues

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Article ; Online: Cross-sectional imaging assessment of renal masses with emphasis on MRI.

Tsili, Athina C / Moulopoulos, Lia-Angela / Varakarakis, Ioannis M / Argyropoulou, Maria I

Acta radiologica (Stockholm, Sweden : 1987)

2021 Volume 63, Issue 11, Page(s) 1570–1587

Abstract: Magnetic resonance imaging (MRI) is a useful complementary imaging tool for the diagnosis and characterization of renal masses, as it provides both morphologic and functional information. A core MRI protocol for renal imaging should include a T1-weighted ...

Abstract	Magnetic resonance imaging (MRI) is a useful complementary imaging tool for the diagnosis and characterization of renal masses, as it provides both morphologic and functional information. A core MRI protocol for renal imaging should include a T1-weighted sequence with in- and opposed-phase images (or, alternatively with DIXON technique), T2-weighted and diffusion-weighted images as well as a dynamic contrast-enhanced sequence with subtraction images, followed by a delayed post-contrast T1-weighted sequence. The main advantages of MRI over computed tomography include increased sensitivity for contrast enhancement, less sensitivity for detection of calcifications, absence of pseudoenhancement, and lack of radiation exposure. MRI may be applied for renal cystic lesion characterization, differentiation of renal cell carcinoma (RCC) from benign solid renal tumors, RCC histologic grading, staging, post-treatment follow-up, and active surveillance of patients with treated or untreated RCC.
MeSH term(s)	Carcinoma, Renal Cell/pathology ; Diagnosis, Differential ; Humans ; Kidney/pathology ; Kidney Diseases, Cystic ; Kidney Neoplasms/pathology ; Magnetic Resonance Imaging/methods
Language	English
Publishing date	2021-10-28
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	105-3
ISSN	1600-0455 ; 0284-1851 ; 0349-652X
ISSN (online)	1600-0455
ISSN	0284-1851 ; 0349-652X
DOI	10.1177/02841851211052999
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Article ; Online: Ultrasonography of the scrotum: Revisiting a classic technique.

Tsili, Athina C / Bougia, Christina K / Pappa, Ourania / Argyropoulou, Maria I

European journal of radiology

2021 Volume 145, Page(s) 110000

Abstract: Conventional US is the primary imaging modality for the evaluation of the scrotum, due to its high resolution, availability, cost-effectiveness and absence of ionizing radiation. Grayscale and color Doppler US provide a comprehensive assessment of ... ...

Abstract	Conventional US is the primary imaging modality for the evaluation of the scrotum, due to its high resolution, availability, cost-effectiveness and absence of ionizing radiation. Grayscale and color Doppler US provide a comprehensive assessment of scrotal diseases. The technique represents the mainstay for imaging of acute scrotum. US is highly accurate in the detection, localization and characterization of scrotal masses. Multiparametric US, including conventional US, contrast-enhanced US and tissue elastography has improved the diagnostic performance of the technique in the assessment of testicular diseases. MRI represents a valuable supplemental imaging tool for the investigation of scrotal pathology, mainly recommended in cases of indeterminate US findings. Recommendations recently issued by the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) refer to the use of scrotal sonography for the evaluation of pathologic entities, including testicular microlithiasis, small, non-palpable incidentally detected testicular masses, varicocele and scrotal trauma. In this review, the technical specifications for scrotal US and the normal sonographic findings are presented. Grayscale and color Doppler US findings of common acute scrotal diseases and scrotal masses are discussed. The complimentary role of multiparametric US and scrotal MRI is addressed. ESUR-SPIWG's guidelines are also reviewed.
MeSH term(s)	Genital Diseases, Male ; Humans ; Magnetic Resonance Imaging ; Male ; Penis/diagnostic imaging ; Scrotum/diagnostic imaging ; Ultrasonography
Language	English
Publishing date	2021-10-23
Publishing country	Ireland
Document type	Journal Article ; Review
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2021.110000
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Article ; Online: Radiological assessment and surgical management of cervical spine involvement in patients with rheumatoid arthritis.

Siempis, Timoleon / Tsakiris, Charalampos / Anastasia, Zikou / Alexiou, George A / Voulgaris, Spyridon / Argyropoulou, Maria I

Rheumatology international

2022 Volume 43, Issue 2, Page(s) 195–208

Abstract: The purpose of the present systematic review was to describe the diagnostic evaluation of rheumatoid arthritis in the cervical spine to provide a better understanding of the indications and options of surgical intervention. We performed a literature ... ...

Abstract	The purpose of the present systematic review was to describe the diagnostic evaluation of rheumatoid arthritis in the cervical spine to provide a better understanding of the indications and options of surgical intervention. We performed a literature review of Pub-med, Embase, and Scopus database. Upon implementing specific inclusion and exclusion criteria, all eligible articles were identified. A total of 1878 patients with Rheumatoid Arthritis (RA) were evaluated for cervical spine involvement with plain radiographs. Atlantoaxial subluxation (AAS) ranged from 16.4 to 95.7% in plain radiographs while sub-axial subluxation ranged from 10 to 43.6% of cases. Anterior atlantodental interval (AADI) was found to between 2.5 mm and 4.61 mm in neutral and flexion position respectively, while Posterior Atlantodental Interval (PADI) was between 20.4 and 24.92 mm. 660 patients with RA had undergone an MRI. A pannus diagnosis ranged from 13.33 to 85.36% while spinal cord compression was reported in 0-13% of cases. When it comes to surgical outcomes, Atlanto-axial joint (AAJ) fusion success rates ranged from 45.16 to 100% of cases. Furthermore, the incidence of postoperative subluxation ranged from 0 to 77.7%. With regards to AADI it is evident that its value decreased in all studies. Furthermore, an improvement in Ranawat classification was variable between studies with a report improvement frequency by at least one class ranging from 0 to 54.5%. In conclusion, through careful radiographic and clinical evaluation, cervical spine involvement in patients with RA can be detected. Surgery is a valuable option for these patients and can lead to improvement in their symptoms.
MeSH term(s)	Humans ; Joint Instability/surgery ; Arthritis, Rheumatoid/diagnostic imaging ; Arthritis, Rheumatoid/surgery ; Radiography ; Magnetic Resonance Imaging/adverse effects ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery
Language	English
Publishing date	2022-11-15
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	8286-7
ISSN	1437-160X ; 0172-8172
ISSN (online)	1437-160X
ISSN	0172-8172
DOI	10.1007/s00296-022-05239-5
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Article: An Overview of the Role of Multiparametric MRI in the Investigation of Testicular Tumors.

Tsili, Athina C / Sofikitis, Nikolaos / Pappa, Ourania / Bougia, Christina K / Argyropoulou, Maria I

Cancers

2022 Volume 14, Issue 16

Abstract: Conventional ultrasonography represents the mainstay of testis imaging. In cases in which ultrasonography is inconclusive, scrotal MRI using a multiparametric protocol may be used as a useful problem-solving tool. MRI of the scrotum is primarily ... ...

Abstract	Conventional ultrasonography represents the mainstay of testis imaging. In cases in which ultrasonography is inconclusive, scrotal MRI using a multiparametric protocol may be used as a useful problem-solving tool. MRI of the scrotum is primarily recommended for differentiating between benign and malignant testicular masses when sonographic findings are ambiguous. This technique is also accurate in the preoperative local staging of testicular tumors and, therefore, is recommended in patients scheduled for testis-sparing surgery. In addition, MRI may provide valuable information regarding the histological characterization of testicular germ-cell tumors, in selected cases. Scrotal MRI may also help in the differentiation between testicular germ-cell neoplasms and non-germ-cell neoplasms. Axial T1-weighted imaging, axial and coronal T2-weighted imaging, axial diffusion-weighted imaging, and coronal subtracted dynamic contrast-enhanced imaging are the minimum requirements for scrotal MRI. A variety of MRI techniques-including diffusion tensor imaging, magnetization transfer imaging, proton MR spectroscopy, volumetric apparent diffusion coefficient histogram analysis, and MRI-based radiomics-are being investigated for testicular mass characterization, providing valuable supplementary diagnostic information. In the present review, we aim to discuss clinical indications for scrotal MRI in cases of testicular tumors, along with MRI findings of common testicular malignancies.
Language	English
Publishing date	2022-08-13
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers14163912
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