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  1. Article ; Online: El tratamiento con bloqueadores del sistema Renina-Angiotensina-Aldosterona no debe suspenderse tras la infección por SARS-CoV-2

    Alfonso Bryce / Arianna Portmann-Baracco / Mayte Bryce-Alberti

    Archivos Peruanos de Cardiología y Cirugía Cardiovascular, Vol 1, Iss 2, Pp 64-

    2020  Volume 66

    Keywords Surgery ; RD1-811 ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Instituto Nacional Cardiovascular - INCOR
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Diabetes increases the risk of COVID-19 in an altitude dependent manner

    Juan Alonso Leon-Abarca / Arianna Portmann-Baracco / Mayte Bryce-Alberti / Carlos Ruiz-Sánchez / Roberto Alfonso Accinelli / Jorge Soliz / Gustavo Francisco Gonzales

    PLoS ONE, Vol 16, Iss 8, p e

    An analysis of 1,280,806 Mexican patients.

    2021  Volume 0255144

    Abstract: Aims The objective of this study is to analyze how the impact of Diabetes Mellitus [DM] in patients with COVID-19 varies according to altitudinal gradient. Methods We obtained 1,280,806 records from adult patients with COVID-19 and DM to analyze the ... ...

    Abstract Aims The objective of this study is to analyze how the impact of Diabetes Mellitus [DM] in patients with COVID-19 varies according to altitudinal gradient. Methods We obtained 1,280,806 records from adult patients with COVID-19 and DM to analyze the probability of COVID-19, development of COVID-19 pneumonia, hospitalization, intubation, admission to the Intensive Care Unit [ICU] and case-fatality rates [CFR]. Variables were controlled by age, sex and altitude of residence to calculate adjusted prevalence and prevalence ratios. Results Patients with DM had a 21.8% higher prevalence of COVID-19 and an additional 120.2% higher prevalence of COVID-19 pneumonia. The adjusted prevalence was also higher for these outcomes as well as for hospitalization, intubation and ICU admission. COVID-19 and pneumonia patients with DM had a 97.0% and 19.4% higher CFR, respectively. With increasing altitudes, the probability of being a confirmed COVID-19 case and the development of pneumonia decreased along CFR for patients with and without DM. However, COVID-19 patients with DM were more likely to require intubation when residing at high altitude. Conclusions The study suggests that patients with DM have a higher probability of being a confirmed COVID-19 case and developing pneumonia. Higher altitude had a protective relationship against SARS-CoV-2 infection; however, it may be associated with more severe cases in patients with and without DM. High altitude decreases CFR for all COVID-19 patients. Our work also shows that women are less affected than men regardless of altitude.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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