LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 2 of total 2

Search options

  1. Article ; Online: Early-onset sepsis: a cohort study comparing serial clinical observation with laboratory testing.

    Salas Garcia, Sandra / Valcarcel Ruescas, Belén / Aristoy Zabaleta, Mercedes / León García, Sonia / Parra-Llorca, Anna / Toledo, Juan Diego

    Journal of perinatology : official journal of the California Perinatal Association

    2021  Volume 41, Issue 10, Page(s) 2482–2487

    Abstract: Objective: Early onset sepsis (EOS) remains a serious and potentially fatal illness. We aimed to demonstrate that serial clinical observation (SCO) is a feasible strategy associated with fewer laboratory evaluations and unnecessary antibiotic use.: ... ...

    Abstract Objective: Early onset sepsis (EOS) remains a serious and potentially fatal illness. We aimed to demonstrate that serial clinical observation (SCO) is a feasible strategy associated with fewer laboratory evaluations and unnecessary antibiotic use.
    Study design: We compared the admissions and antibiotic therapy in neonates ≥35 weeks' gestation at risk for EOS in a prospective cohort after the implementation of a new protocol based on SCO (n = 381) with a historical cohort which received laboratory testing (n = 417).
    Results: There was a significant reduction in admissions for suspected sepsis (7.2% vs 2.9%, p = 0.006) and the use of antibiotics (6.1% vs 0.7%, p = 0.000) in the cohort based on SCO. There was no delay in diagnosis.
    Conclusions: SCO in neonates ≥35 weeks' gestation at risk for EOS, including chorioamnionitis-exposed infants, is a feasible measure that reduces laboratory evaluations and the overuse of antibiotics respecting the bonding mother-infant.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Cohort Studies ; Female ; Humans ; Infant ; Infant, Newborn ; Neonatal Sepsis/diagnosis ; Neonatal Sepsis/drug therapy ; Neonatal Sepsis/epidemiology ; Pregnancy ; Prospective Studies ; Risk Assessment ; Sepsis/diagnosis ; Sepsis/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-021-01138-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2412: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Risk Measurement of Perinatal and Neonatal Morbidity Characteristics and Applicability of GAIA Case Definitions: Results and Lessons Learnt of a Hospital-Based Prospective Cohort Study in the Valencia Region (2019-2020).

    Carmona, Antonio / Latorre Tejerina, María / Martínez Sebastián, Alicia / Dobreva, Dafina / Jurca, Cristina P / Huerta Barberá, Sergio / Bernat Montoya, Vicente / Aristoy Zabaleta, Mercedes / Pineda Caplliure, Ana / Mansilla Roig, Beatriz / Navío Anaya, María / Tosca-Segura, Ricardo / Tortajada-Girbés, Miguel / Díez-Domingo, Javier / Orrico-Sánchez, Alejandro

    International journal of environmental research and public health

    2022  Volume 19, Issue 12

    Abstract: Post-marketing safety surveillance of new vaccines aimed to be administered during pregnancy is crucial to orchestrate efficient adverse events evaluation. This is of special relevance in the current landscape of new vaccines being introduced in the ... ...

    Abstract Post-marketing safety surveillance of new vaccines aimed to be administered during pregnancy is crucial to orchestrate efficient adverse events evaluation. This is of special relevance in the current landscape of new vaccines being introduced in the pregnant women population, and particularly due to the recent administration of COVID-19 vaccines in pregnant women. This multi-center prospective cohort study, nested within the WHO-Global Vaccine Safety-MCC study, involved two hospitals in the Valencia region. Hereby, the incidence rates of seven perinatal and neonatal outcomes in the Valencia region are presented. The pooled data analysis of the two Valencian hospitals allowed the estimation of incidence rates in the Valencia Region (per 1000 live births): 86.7 for low birth weight, 78.2 for preterm birth, 58.8 for small for gestational age, 13 for congenital microcephaly, 0.4 for stillbirth, 1.2 for neonatal death and 6.5 for neonatal infection. These figures are in line with what is expected from a high-income country and the previously reported rates for Spain and Europe, except for the significantly increased rate for congenital microcephaly. Regarding the data for maternal immunization, the vaccination status was collected for 94.4% of the screened pregnant women, highlighting the high quality of the Valencian Vaccine Registry. The study also assessed the Valencian hospitals' capacity for identifying and collecting data on maternal immunization status, as well as the applicability of the GAIA definitions to the identified outcomes.
    MeSH term(s) Adolescent ; COVID-19 ; COVID-19 Vaccines ; Female ; Hospitals ; Humans ; Infant, Newborn ; Microcephaly ; Morbidity ; Pregnancy ; Pregnancy Outcome ; Premature Birth/epidemiology ; Prospective Studies ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2022-06-10
    Publishing country Switzerland
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19127132
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top