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  1. Article: A novel technique for performing aspiration biopsies - A technical report.

    Ariyaratne, Sisith P / Purohit, Neeraj / Botchu, Rajesh

    Journal of clinical orthopaedics and trauma

    2024  Volume 48, Page(s) 102339

    Abstract: An aspiration biopsy is a commonly performed procedure for diagnostic sampling, particularly for sampling of cystic soft tissue lesions and bone marrow. The method is also useful for diagnostic sampling of bone lesions, particularly cystic and lytic ... ...

    Abstract An aspiration biopsy is a commonly performed procedure for diagnostic sampling, particularly for sampling of cystic soft tissue lesions and bone marrow. The method is also useful for diagnostic sampling of bone lesions, particularly cystic and lytic osseous lesions where traditional methods of core biopsy may yield little to no material. Performing a successful aspiration biopsy involves aspiration of the lesion's contents and curettage of the walls. This requires maintaining a constant negative pressure on the syringe, which can be challenging with bone biopsies, as it requires one hand to maintain significant pressure on the plunger while the other hand manipulates the needle within the lesion. We describe a novel technique for performing aspiration biopsies of these lesions which allows maintenance of constant negative pressure on the syringe and frees up both the proceduralist's hands for better control of the needle.
    Language English
    Publishing date 2024-01-10
    Publishing country India
    Document type Case Reports
    ZDB-ID 2596956-0
    ISSN 2213-3445 ; 0976-5662
    ISSN (online) 2213-3445
    ISSN 0976-5662
    DOI 10.1016/j.jcot.2024.102339
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  2. Article ; Online: An unusual case of primary tuberculosis of the patella and patellar tendon masquerading as gout.

    Ariyaratne, Sisith / Mohan, Rahul / Botchu, Rajesh

    Journal of ultrasound

    2024  

    Abstract: Tuberculosis (TB), an infection caused by Mycobacterium tuberculosis, accounts for significant morbidity and mortality worldwide. While primary TB predominantly involves the respiratory system, approximately 10-19% patients have musculoskeletal ... ...

    Abstract Tuberculosis (TB), an infection caused by Mycobacterium tuberculosis, accounts for significant morbidity and mortality worldwide. While primary TB predominantly involves the respiratory system, approximately 10-19% patients have musculoskeletal involvement. We present a case of a 54-year-old year gentleman with insidious onset of anterior knee pain. Imaging demonstrated a soft tissue lesion involving the patellar tendon and eroding the inferior pole of the patella. The imaging features, particularly ultrasound, resembled those that are typically seen with gout. Ultrasound guided biopsy revealed this to be TB of the patella. The patient was successfully treated with antitubercular therapy. Musculoskeletal TB, while usually not a primary form of TB, is an important consideration particularly in patients with risk factors for the disease. Its imaging features can mimic other forms of arthropathy such as gout. Moreover, while the knee is a relatively common site for TB infection, isolated involvement of the patella and patellar tendon is extremely rare. The case highlights the possibility of rare musculoskeletal manifestation of TB as a well as a potential imaging pitfall of TB infection mimicking gout, which is an important consideration in clinical practice.
    Language English
    Publishing date 2024-02-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-023-00859-4
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  3. Article ; Online: An unusual case of metastatic melanoma in subcutaneous tissue presenting as a solitary cystic mass with fluid levels.

    Cubitt, Catherine / Ariyaratne, Sisith / Vaiyapuri, Sumathi / Kurisunkal, Vineet / Botchu, Rajesh

    Journal of ultrasound

    2024  

    Abstract: Malignant melanoma is a common and often aggressive neoplasm of the skin arising from melanocytes. Metastatic melanoma is known for its diverse clinical manifestations, and can present with atypical features prior to diagnosis of the primary lesion, ... ...

    Abstract Malignant melanoma is a common and often aggressive neoplasm of the skin arising from melanocytes. Metastatic melanoma is known for its diverse clinical manifestations, and can present with atypical features prior to diagnosis of the primary lesion, which can pose a diagnostic challenge. We report a rare case of metastatic melanoma in a 67 year-old male who presented with a painless, enlarging mass in the right axilla over a 4 week period. Ultrasound and magnetic resonance imaging (MRI) scans revealed a well-defined solitary, cystic appearing lesion in the right axilla with a distinct fluid-fluid level. An ultrasound guided biopsy of the lesion diagnosed a metastatic melanoma. While haemorrhagic distant metastases are a well-recognised complication of malignant melanoma, particularly in the brain and lung, soft tissue metastases presenting with fluid-fluid levels is not well described in the literature. The case highlights the importance of considering the differential of melanoma metastasis when encountered with such a lesion and importance of ultrasound guided biopsy for histopathological confirmation, as the imaging features can mimic that of a haemorrhagic soft tissue sarcoma, the management of which differs substantially from that of melanoma.
    Language English
    Publishing date 2024-02-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-023-00864-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Will collaborative publishing with ChatGPT drive academic writing in the future?

    Ariyaratne, Sisith / Iyengar, Kathikeyan P / Botchu, Rajesh

    The British journal of surgery

    2023  Volume 110, Issue 9, Page(s) 1213–1214

    MeSH term(s) Humans ; Writing ; Publishing
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znad198
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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Author response to: Comment on: Will collaborative publishing with ChatGPT drive academic writing in the future?

    Ariyaratne, Sisith / Iyengar, Karthikeyan P / Botchu, Rajesh

    The British journal of surgery

    2023  Volume 110, Issue 12, Page(s) 1894

    MeSH term(s) Humans ; Publishing ; Writing
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znad295
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  6. Article: ChatGPT in academic publishing: An ally or an adversary?

    Ariyaratne, Sisith / Botchu, Rajesh / Iyengar, Karthikeyan P

    Scottish medical journal

    2023  Volume 68, Issue 3, Page(s) 129–130

    Language English
    Publishing date 2023-05-07
    Publishing country Scotland
    Document type Letter
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/00369330231174231
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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: A rare case of an intraneural ganglion cyst of the median nerve

    Ariyaratne Sisith / Pathak Gora / Iyengar Karthikeyan / Botchu Rajesh / Shah Amit

    Journal of Ultrasonography, Vol 23, Iss 94, Pp e161-e

    2023  Volume 164

    Abstract: Intraneural ganglion cysts are a relatively uncommon type of ganglion cyst that can affect peripheral nerves. They are particularly rare in the upper limb, and even more so in the median nerve, with the vast majority of them occurring in the peroneal ... ...

    Abstract Intraneural ganglion cysts are a relatively uncommon type of ganglion cyst that can affect peripheral nerves. They are particularly rare in the upper limb, and even more so in the median nerve, with the vast majority of them occurring in the peroneal nerves. This paper aims to make the reader aware of this relatively uncommon condition.
    Keywords median nerve ; peripheral nerve ; intraneural ganglion cyst ; ganglion cyst ; Medicine (General) ; R5-920 ; Medical technology ; R855-855.5
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The clinical significance of indeterminate pulmonary nodules in patients with primary bone sarcoma: a systematic review.

    Hassan, M Shihabul / Ariyaratne, Sisith / Azzopardi, Christine / Iyengar, Karthikeyan P / Davies, Arthur Mark / Botchu, Rajesh

    The British journal of radiology

    2024  Volume 97, Issue 1156, Page(s) 747–756

    Abstract: Objective: To report the incidence of indeterminate pulmonary nodules (IPN) and the rate of progression of IPNs to metastasis in patients with primary bone cancers. We also aimed to evaluate clinical or radiological parameters that may identify IPNs ... ...

    Abstract Objective: To report the incidence of indeterminate pulmonary nodules (IPN) and the rate of progression of IPNs to metastasis in patients with primary bone cancers. We also aimed to evaluate clinical or radiological parameters that may identify IPNs more likely to progress to metastatic disease and their effect on overall or event-free survival in patients with primary bone sarcoma.
    Methods: A systematic search of the electronic databases Medline, Embase, and Cochrane Library was undertaken for eligible articles on IPNs in patients with primary bone sarcomas, published in the English language from inception of the databases to 2023. The Newcastle-Ottawa Quality Assessment Form for Cohort Studies was utilized to evaluate risk of bias in included studies.
    Results: Six studies, involving 1667 patients, were included in this systematic review. Pooled quantitative analysis found the rate of incidence of IPN to be 18.1% (302 out of 1667) and the rate of progression to metastasis to be 45.0% (136 out of 302). Nodule size (more than 5 mm diameter), number (more than or equal to 4), distribution (bilaterally distributed), incomplete calcification, and lobulated margins were associated with an increased likelihood of IPNs progressing to metastasis, however, their impact on overall or event-free survival remains unclear.
    Conclusion: The risk of IPNs progressing to metastasis in patients with primary bone sarcoma is non-negligible. Large IPNs have a high risk to be an actual metastasis. We suggest that IPNs in these patients be followed up for a minimum of 2 years with CT imaging at 3, 6, and 12 month intervals, particularly for nodules measuring >5 mm in average diameter.
    Advances in knowledge: This is the first systematic review on IPNs in patients with primary bone sarcomas only and proposes viable management strategies for such patients.
    MeSH term(s) Humans ; Lung Neoplasms/pathology ; Clinical Relevance ; Multiple Pulmonary Nodules/pathology ; Bone Neoplasms/diagnostic imaging ; Sarcoma/diagnostic imaging ; Osteosarcoma/diagnostic imaging
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Systematic Review ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1093/bjr/tqae040
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  9. Article: A rare case of an intraneural ganglion cyst of the median nerve.

    Ariyaratne, Sisith / Pathak, Gora / Iyengar, Karthikeyan / Botchu, Rajesh / Shah, Amit

    Journal of ultrasonography

    2023  Volume 23, Issue 94, Page(s) e161–e164

    Abstract: Aim of the study: Intraneural ganglion cysts are a relatively uncommon type of ganglion cyst that can affect peripheral nerves. They are particularly rare in the upper limb, and even more so in the median nerve, with the vast majority of them occurring ... ...

    Abstract Aim of the study: Intraneural ganglion cysts are a relatively uncommon type of ganglion cyst that can affect peripheral nerves. They are particularly rare in the upper limb, and even more so in the median nerve, with the vast majority of them occurring in the peroneal nerves. This paper aims to make the reader aware of this relatively uncommon condition.
    Case description: We report a case of a 41-year-old male who presented with a gradually progressing mass on the volar aspect of the wrist extending to the index finger. The nonspecific presentation as well as the rarity of the condition may make diagnosis challenging. The patient was referred for surgical management under a specialist peripheral nerve hand surgeon.
    Conclusions: Ultrasound and magnetic resonance imaging as well as awareness of the typical imaging features of this entity are crucial in making the correct diagnosis as well as excluding other potential considerations such as neoplasm.
    Language English
    Publishing date 2023-09-11
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2843824-3
    ISSN 2084-8404
    ISSN 2084-8404
    DOI 10.15557/jou.2023.0025
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  10. Article: Current role and future applications of image-guided interventional procedures in musculoskeletal oncology - A narrative review.

    Hegde, Ganesh / Iyengar, Karthikeyan P / Kurisunkal, Vineet / Sharma, Gaurav Kant / Ariyaratne, Sisith / Botchu, Rajesh

    Journal of orthopaedics

    2023  Volume 44, Page(s) 99–106

    Abstract: Background: Musculoskeletal (MSK) image-guided interventional procedures have been increasingly used in and remain crucial in the diagnosis and treatment of musculoskeletal tumours.: Aims: In this article, we aim to describe commonly performed ... ...

    Abstract Background: Musculoskeletal (MSK) image-guided interventional procedures have been increasingly used in and remain crucial in the diagnosis and treatment of musculoskeletal tumours.
    Aims: In this article, we aim to describe commonly performed interventional procedures in the subspeciality of MSK oncology drawing experience from our tertiary referral centre. Recent advances, emerging techniques and future applications of image-guided interventional procedures in the field of MSK oncology are highlighted.
    Material and methods: A retrospective search using the keyword 'musculoskeletal system', 'neoplasms', 'biopsy', and 'interventional radiology' was performed at our tertiary care oncology orthopaedic referral centre radiology database. The radiology images were collected from our Picture Archiving and Communication System (PACS) and Radiology Information System (RIS). Electronic Patient Records, histopathology laboratory records and patient characteristics were collaborated to generate this narrative experience at our centre.
    Results: Image-guided interventional procedures have been utilised in a spectrum of primary and secondary MSK tumours. Current applications include diagnosis of bone and soft tissue MSK neoplastic lesions with biopsies, thermal, cryotherapy and Radiofrequency ablations and augmentation procedures.
    Conclusion: Musculoskeletal (MSK) image-guided interventions have increasing applications in the diagnosis, management, treatment and monitoring of patients with MSK tumours. The emergence of newer imaging technologies with enhanced skills of interventional radiologists will allow a range of therapeutic MSK interventions in both effective control of primary lesions and palliative care of metastatic lesions.
    Language English
    Publishing date 2023-09-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240839-3
    ISSN 0972-978X
    ISSN 0972-978X
    DOI 10.1016/j.jor.2023.08.011
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