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  1. Article ; Online: SMOKING AND OTHER ADDICTIONS RELATED TO CANCER OF THE HEAD AND NECK

    Arjun Gurmeet Singh / Pankaj Chaturvedi

    Revista Médica Clínica Las Condes, Vol 29, Iss 4, Pp 405-

    2018  Volume 410

    Abstract: Head and neck canceris a major health problem globally with the projected incidence of 1,176,149 cases, an approximate 20% increase, in 2020. Most research today is directed towards reducing this incidence by understanding the mechanism and etiologic ... ...

    Abstract Head and neck canceris a major health problem globally with the projected incidence of 1,176,149 cases, an approximate 20% increase, in 2020. Most research today is directed towards reducing this incidence by understanding the mechanism and etiologic factors associated. Majority of these factors are habitual, with tobacco use being the most common. There are many variations in the use of tobacco ranging from smoked to smokeless, as well as novel innovations like e-cigarette and tobacco tablets, being introduced today. There are also many studies suggesting tobacco use as a gateway drug to other habitual substances, including alcohol and marijuana use. Many of these substances are now being utilized more by the youth than adults, which might develop a shift in the age of incidence in the future. Few countries have asignificant population of immigrants, who bring with thema diverse range of traditional habits, the effects of which still have to be studied on the population. An overview of the various habitual etiologiesassociated with head and neck cancers, and their mechanism of action have been reviewed here so as to get a holistic idea of these substances. Resumen: El cáncer de cabeza y cuello es un problema de salud relevante en el mundo, con una incidencia proyectada de 1176149 casos, un aumento aproximado del 20%, en 2020. La mayoría de las investigaciones actuales apuntan a reducir esta incidencia con la comprensión de los mecanismo de su génesis y los factores etiológicos asociados. La mayoría de estos factores son adicciones, siendo el uso del tabaco el más común. Hay muchas variaciones en el uso del tabaco que van desde con o sin combustión, así como novedosas innovaciones como el cigarrillo electrónico y las tabletas de tabaco, que se están introduciendo hoy en día. También hay muchos estudios que sugieren el uso del tabaco como una droga de entrada al uso de otras sustancias adictivas, incluido el consumo de alcohol y marihuana. Muchas de estas sustancias ahora están siendo utilizadas más por los ...
    Keywords Medicine ; R
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Cross-Sectional and Longitudinal Mental Health Status Prevailing among COVID-19 Patients in Mumbai, India

    Arjun Gurmeet Singh / Hitesh Singhavi / Florida Sharin / Muffazal Lakdawala / Sharayu Mhatre / Jayita Deodhar / Pankaj Chaturvedi / Rajesh Dikshit

    Indian Journal of Community Medicine, Vol 47, Iss 1, Pp 55-

    2022  Volume 60

    Abstract: Introduction: The aim was to determine the prevalence and predictors of depression among less symptomatic COVID-19 patients. Methods: A questionnaire-based assessment was conducted among asymptomatic or mildly symptomatic COVID-19 patients when admitted ... ...

    Abstract Introduction: The aim was to determine the prevalence and predictors of depression among less symptomatic COVID-19 patients. Methods: A questionnaire-based assessment was conducted among asymptomatic or mildly symptomatic COVID-19 patients when admitted in a COVID-19 facility (T1) and after 6 months (T2). Interviews were conducted using the Patient Health Questionnaire-9 instrument. Socio-demographic details and length of facility stay were recorded. Changes in scores between the two-time points T1 and T2 were compared. Factors predicting depression were determined using Chi-square and Mann–Whitney U test during facility stay, and those predicting worsening over time were obtained using multivariate regression models. Results: Among the 91.4% (n = 450) participants, prevalence of depression was 38.4% (95% confidence interval [CI] = 34.0–43.0) with a significant increase of 7.8-fold (95% CI = 4.8–12.8) in depression as the duration of stay increased beyond a median of 5 days. A significant association was observed between higher income and lower depression (odds ratios = 0.6, P = 0.03). 84% (n = 378) responded at the second timepoint assessment after a median of 6.62 months (T2). There was a significant difference observed between the 2.6% (n = 6) that worsened into depression at T2 and the 73.8% (n = 107) that improved out of depression at T2 (P ≤ 0.001). Age >45 years (P = 0.007), males (P = 0.011) and reinfection (P = 0.039) significantly led to worsening of depression. Conclusion: There is a need for actively detecting and managing depression in institutionally quarantined survivors, considering limiting such quarantine to no more than a week, and providing routine screening and care for depression beyond this period.
    Keywords coronavirus ; covid-19 ; depression ; india ; mental health ; Public aspects of medicine ; RA1-1270
    Subject code 150
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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