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  1. Article ; Online: Suicide attempts in eating disorder subtypes: a meta-analysis of the literature employing DSM-IV, DSM-5, or ICD-10 diagnostic criteria.

    Mandelli, Laura / Arminio, Angelo / Atti, Anna-Rita / De Ronchi, Diana

    Psychological medicine

    2018  Volume 49, Issue 8, Page(s) 1237–1249

    Abstract: Background: Quantification of suicidal risk in specific populations is important for the adoption of targeted prevention and harm reduction measures. Though there remains little systematic evidence, risk of suicide attempts for bulimia nervosa (BN) and ... ...

    Abstract Background: Quantification of suicidal risk in specific populations is important for the adoption of targeted prevention and harm reduction measures. Though there remains little systematic evidence, risk of suicide attempts for bulimia nervosa (BN) and binge-purging anorexia nervosa (AN-bp) appears higher than restrictive AN (AN-r); risk in binge eating disorder (BED) is still unclear. The aim of this meta-analysis was to compare proportions of suicide attempts in eating disorder (ED) subgroups.
    Methods: A literature search using combinations of key-words for ED and suicide attempts was performed. Studies reporting proportions of suicide attempters in at least two ED groups, diagnosed according to DSM-IV or -5 and ICD-10 diagnostic criteria were considered. ED subgroups were analyzed in pairs using a binary random effect model for proportions. Publication bias, meta-regression, and sensitivity analyses were performed.
    Results: In BN, attempted suicide was more frequent (21%) than in AN (12.5%), but the difference was statistically significant only when BN was compared with AN-r (9-10%). In BED, the proportion of suicide attempts was as high as in AN (10-12%).
    Conclusions: Though limited by heterogeneity across the studies in terms of methodology and aims, inability to control for relevant confounding variables, exclusion of ED not otherwise specified, this study supports suicide attempts as a major issue in EDs, especially in binge-purging subtypes, i.e. BN and AN-bp. Similar suicidal proportions were observed in AN and BED. The reasons for a greater proportion of attempted suicide in binge/purging subtypes need to be explored in future studies.
    MeSH term(s) Anorexia Nervosa/diagnosis ; Anorexia Nervosa/psychology ; Binge-Eating Disorder/diagnosis ; Binge-Eating Disorder/psychology ; Bulimia Nervosa/diagnosis ; Bulimia Nervosa/psychology ; Diagnostic and Statistical Manual of Mental Disorders ; Humans ; International Classification of Diseases ; Suicide, Attempted/statistics & numerical data
    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 217420-0
    ISSN 1469-8978 ; 0033-2917
    ISSN (online) 1469-8978
    ISSN 0033-2917
    DOI 10.1017/S0033291718003549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intravascular large B-cell lymphoma affecting multiple cranial nerves: A histopathological study.

    Porzionato, Andrea / Pelletti, Guido / Barzon, Luisa / Contran, Martina / Emmi, Aron / Arminio, Angelo / Macchi, Veronica / De Caro, Raffaele

    Neuropathology : official journal of the Japanese Society of Neuropathology

    2021  Volume 41, Issue 5, Page(s) 396–405

    Abstract: Intravascular large B-cell lymphoma (IVLBCL) is a rare form of lymphomas with poor prognosis, characterized by atypical lymphocytes selectively growing within the lumen of small or medium-sized vessels. Here, we report a case of intracerebral IVLBCL in a ...

    Abstract Intravascular large B-cell lymphoma (IVLBCL) is a rare form of lymphomas with poor prognosis, characterized by atypical lymphocytes selectively growing within the lumen of small or medium-sized vessels. Here, we report a case of intracerebral IVLBCL in a 54-year-old man who died three months after symptom onset. The diagnosis was made by postmortem pathological examination, based on the identification of multiple ischemic lesions, with small or medium-sized vessels filled with malignant B-cells, in the cerebral hemispheres, cerebellum, midbrain, and medulla oblongata, including the external cuneate nucleus and trigeminal spinal tract nucleus. Apart from necrotic lesions, specific histopathological search for occluded vessels in the other brain stem structures permitted identification of significant involvement of the cuneate nucleus, solitary tract nucleus, hypoglossal nucleus, and inferior olivary complex. Small vessels affected by IVLBCL were also found in the trunks of the oculomotor, trigeminal, glossopharyngeal, vagal, and hypoglossal nerves. These histopathological findings were consistent with some cranial nerve symptoms/signs ascertained during hospitalization, such as diplopia, dysphonia, and asymmetry/hypomotility of the palatal veil. The case study presented here reports novel insights on radiological, anatomical, and clinical correlations of the IVLBCL, including the possible involvement of nuclei and trunks of multiple cranial nerves. The reported findings may help clinicians in the early identification of this rapidly progressive disease that can be easily misdiagnosed, through integrated neuroradiological, neurological and neuropathological approaches.
    MeSH term(s) Autopsy ; Cranial Nerves ; Humans ; Lymphoma, Large B-Cell, Diffuse ; Male ; Middle Aged ; Motor Neurons
    Language English
    Publishing date 2021-09-19
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 1483794-8
    ISSN 1440-1789 ; 0919-6544
    ISSN (online) 1440-1789
    ISSN 0919-6544
    DOI 10.1111/neup.12767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Estrogen-Receptor-Positive Breast Cancer in Postmenopausal Women: The Role of Body Composition and Physical Exercise.

    Dimauro, Ivan / Grazioli, Elisa / Antinozzi, Cristina / Duranti, Guglielmo / Arminio, Alessia / Mancini, Annamaria / Greco, Emanuela A / Caporossi, Daniela / Parisi, Attilio / Di Luigi, Luigi

    International journal of environmental research and public health

    2021  Volume 18, Issue 18

    Abstract: Breast cancer (BC) is the most commonly diagnosed cancer among women worldwide and the most common cause of cancer-related death. To date, it is still a challenge to estimate the magnitude of the clinical impact of physical activity ( ...

    Abstract Breast cancer (BC) is the most commonly diagnosed cancer among women worldwide and the most common cause of cancer-related death. To date, it is still a challenge to estimate the magnitude of the clinical impact of physical activity (
    MeSH term(s) Body Composition ; Breast Neoplasms/epidemiology ; Breast Neoplasms/prevention & control ; Estrogens ; Exercise ; Female ; Humans ; Postmenopause ; Risk Factors
    Chemical Substances Estrogens
    Language English
    Publishing date 2021-09-18
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph18189834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Smoking and life expectancy among HIV-infected individuals on antiretroviral therapy in Europe and North America.

    Helleberg, Marie / May, Margaret T / Ingle, Suzanne M / Dabis, Francois / Reiss, Peter / Fätkenheuer, Gerd / Costagliola, Dominique / d'Arminio, Antonella / Cavassini, Matthias / Smith, Colette / Justice, Amy C / Gill, John / Sterne, Jonathan A C / Obel, Niels

    AIDS (London, England)

    2015  Volume 29, Issue 2, Page(s) 221–229

    Abstract: Background: Cardiovascular disease and non-AIDS malignancies have become major causes of death among HIV-infected individuals. The relative impact of lifestyle and HIV-related factors are debated.: Methods: We estimated associations of smoking with ... ...

    Abstract Background: Cardiovascular disease and non-AIDS malignancies have become major causes of death among HIV-infected individuals. The relative impact of lifestyle and HIV-related factors are debated.
    Methods: We estimated associations of smoking with mortality more than 1 year after antiretroviral therapy (ART) initiation among HIV-infected individuals enrolled in European and North American cohorts. IDUs were excluded. Causes of death were assigned using standardized procedures. We used abridged life tables to estimate life expectancies. Life-years lost to HIV were estimated by comparison with the French background population.
    Results: Among 17,995 HIV-infected individuals followed for 79,760 person-years, the proportion of smokers was 60%. The mortality rate ratio (MRR) comparing smokers with nonsmokers was 1.94 [95% confidence interval (95% CI) 1.56-2.41]. The MRRs comparing current and previous smokers with never smokers were 1.70 (95% CI 1.23-2.34) and 0.92 (95% CI 0.64-1.34), respectively. Smokers had substantially higher mortality from cardiovascular disease, non-AIDS malignancies than nonsmokers [MRR 6.28 (95% CI 2.19-18.0) and 3.31 (95% CI 1.80-5.45), respectively]. [corrected]. Among 35-year-old HIV-infected men, the loss of life-years associated with smoking and HIV was 7.9 (95% CI 7.1-8.7) and 5.9 (95% CI 4.9-6.9), respectively. The life expectancy of virally suppressed, never-smokers was 43.5 years (95% CI 41.7-45.3), compared with 44.4 years among 35-year-old men in the background population. Excess MRRs/1000 person-years associated with smoking increased from 0.6 (95% CI -1.3 to 2.6) at age 35 to 43.6 (95% CI 37.9-49.3) at age at least 65 years.
    Conclusion: Well treated HIV-infected individuals may lose more life years through smoking than through HIV. Excess mortality associated with smoking increases markedly with age. Therefore, increases in smoking-related mortality can be expected as the treated HIV-infected population ages. Interventions for smoking cessation should be prioritized.
    MeSH term(s) Adult ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; Cohort Studies ; Europe ; Female ; HIV Infections/drug therapy ; HIV Infections/mortality ; Humans ; Life Expectancy/trends ; Male ; Middle Aged ; North America ; Smoking/epidemiology
    Language English
    Publishing date 2015-01-14
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000000540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: What are the bone lesions in patients with more than four years of a functioning renal transplant?

    Carlini, R G / Rojas, E / Arminio, A / Weisinger, J R / Bellorin-Font, E

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    1998  Volume 13 Suppl 3, Page(s) 103–104

    MeSH term(s) Adult ; Aged ; Bone Density ; Bone and Bones/pathology ; Female ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Parathyroid Hormone/blood
    Chemical Substances Parathyroid Hormone
    Language English
    Publishing date 1998
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/13.suppl_3.103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Comparison of single and boosted protease inhibitor versus nonnucleoside reverse transcriptase inhibitor-containing cART regimens in antiretroviral-naïve patients starting cART after January 1, 2000.

    Mocroft / Horban / Clumeck / Stellbrink / Monforte, d'Arminio A / Zilmer / Kirk / Gatell / Phillips / Lundgren

    HIV clinical trials

    2006  Volume 7, Issue 6, Page(s) 271–284

    Abstract: Background: Few published studies have considered both the short- and long-term virologic or immunologic response to combination antiretroviral therapy (cART) and the impact of different cART strategies.: Purpose: To compare time to initial virologic ...

    Abstract Background: Few published studies have considered both the short- and long-term virologic or immunologic response to combination antiretroviral therapy (cART) and the impact of different cART strategies.
    Purpose: To compare time to initial virologic (<500 copies/mL) or immunologic (>200/mm3 cell increase) response in antiretroviral-naïve patients starting either a single protease inhibitor (PI; n = 183), a ritonavir-boosted PI regimen (n = 197), or a nonnucleoside reverse transcriptase inhibitor (NNRTI)-based cART regimen (n = 447) after January 1, 2000, and the odds of lack of virologic or immunologic response at 3 years after starting cART.
    Method: Cox proportional hazards models and logistic regression.
    Results: After adjustment, compared to patients taking an NNRTI-regimen, patients taking a single-PI regimen were significantly less likely to achieve a viral load (VL) <500 copies/mL (relative hazard [RH] 0.74, 95% CI 0.54-0.84, p = .0005); there was no difference between the boosted-PI regimen and the NNRTI regimen (p = .72). There were no differences between regimens in the risk of >200/mm3 CD4 cell increase after starting cART (p > .3). At 3 years after starting cART, patients taking a single-PI-based regimen were more likely to not have virologic suppression (<500 copies/mL; odds ratio [OR] 1.60, 95% CI 1.06-2.40, p = .024), while there were no differences in the odds of having an immunologic response (>200/mm3 increase; p > .15). This model was adjusted for CD4 and VL at starting cART, age, prior AIDS diagnosis, year of starting cART, and region of Europe.
    Conclusion: Compared to patients starting an NNRTI-based regimen, patients starting a single-PI regimen were less likely to be virologically suppressed at 3 years after starting cART. These results should be interpreted with caution, because of the potential biases associated with observational studies. Ultimately, clinical outcomes, such as new AIDS diagnoses or deaths, will be the measure of efficacy of cART regimens, which requires the follow-up of a very large number of patients over many years.
    MeSH term(s) Analysis of Variance ; Anti-HIV Agents/administration & dosage ; Antiretroviral Therapy, Highly Active ; Female ; HIV Infections/blood ; HIV Infections/drug therapy ; HIV Protease Inhibitors/administration & dosage ; HIV Protease Inhibitors/immunology ; HIV Protease Inhibitors/therapeutic use ; Humans ; Male ; Reverse Transcriptase Inhibitors/administration & dosage ; Reverse Transcriptase Inhibitors/immunology ; Reverse Transcriptase Inhibitors/therapeutic use ; Viral Load
    Chemical Substances Anti-HIV Agents ; HIV Protease Inhibitors ; Reverse Transcriptase Inhibitors
    Language English
    Publishing date 2006-11
    Publishing country England
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2060516-X
    ISSN 1528-4336
    ISSN 1528-4336
    DOI 10.1310/hct0706-271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bone disease in patients with long-term renal transplantation and normal renal function.

    Carlini, R G / Rojas, E / Weisinger, J R / Lopez, M / Martinis, R / Arminio, A / Bellorin-Font, E

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2000  Volume 36, Issue 1, Page(s) 160–166

    Abstract: Renal osteodystrophy may persist during the early years after renal transplantation. However, information on bone status after a successful long-term renal transplantation is limited. We examined biochemical parameters, bone mineral density (BMD), and ... ...

    Abstract Renal osteodystrophy may persist during the early years after renal transplantation. However, information on bone status after a successful long-term renal transplantation is limited. We examined biochemical parameters, bone mineral density (BMD), and bone histomorphometry in 25 asymptomatic men with normal renal function after 7.5 +/- 5.7 years of a renal transplantation. Serum calcium, phosphorus, alkaline phosphatase, and 1,25(OH)(2)D(3) levels and urinary calcium level and cyclic andenosine monophosphate excretion were within normal range in all patients. Serum intact parathyroid hormone (PTH) level was elevated in 11 subjects (133.6 +/- 78 pg/mL) and normal in the other 14 subjects (47.9 +/- 13.6 pg/mL). Mean BMD at the lumbar spine and femoral neck was low in the entire group. However, it progressively increased as time after transplantation increased, approaching normal values after 10 years. Bone histomorphometric analysis showed bone resorption, osteoid volume, and osteoid surface greater than normal range in the majority of patients. Bone formation rate and mineralization surface were low, and mineralization time was delayed in most patients. These lesions were more severe in patients after 3 to 4 years of transplantation but improved with time and approached normal values after a period of 10 years. PTH values did not correlate with bone histological characteristics or BMD. These results show that the bone alterations observed after long-term renal transplantation consist of a mixed bone disease in which features of high bone turnover coexist with altered bone formation and delayed mineralization. These findings may result from the combined effect of preexisting bone disease and immunosuppressive therapy.
    MeSH term(s) Adult ; Aged ; Alkaline Phosphatase/blood ; Biopsy ; Bone Density ; Bone and Bones/pathology ; Calcium/blood ; Chronic Kidney Disease-Mineral and Bone Disorder/blood ; Chronic Kidney Disease-Mineral and Bone Disorder/diagnosis ; Chronic Kidney Disease-Mineral and Bone Disorder/pathology ; Creatinine/blood ; Cross-Sectional Studies ; Femur ; Humans ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation/adverse effects ; Lumbar Vertebrae ; Male ; Middle Aged ; Parathyroid Hormone/blood ; Phosphorus/blood ; Time Factors
    Chemical Substances Immunosuppressive Agents ; Parathyroid Hormone ; Phosphorus (27YLU75U4W) ; Creatinine (AYI8EX34EU) ; Alkaline Phosphatase (EC 3.1.3.1) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2000-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/ajkd.2000.8289
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  8. Article: Hallazgos endoscópicos del tracto digestivo superior en pacientes con insuficiencia renal crónica terminal.

    Benzo, J / Matos, M / Milanes, C / Arminio, A / Stempel, C A

    G.E.N

    1994  Volume 48, Issue 1, Page(s) 34–38

    Abstract: We studied patients undergoing hemodialysis awaiting renal transplantation who had routine endoscopy as preoperative evaluation. Medical histories of 71 patients transplanted between 1982-1989 were reviewed retrospectively in order to determine the ... ...

    Title translation Endoscopic findings in the upper digestive tract in patients with terminal chronic kidney failure.
    Abstract We studied patients undergoing hemodialysis awaiting renal transplantation who had routine endoscopy as preoperative evaluation. Medical histories of 71 patients transplanted between 1982-1989 were reviewed retrospectively in order to determine the results of the upper gastrointestinal lesions. At the time of the endoscopy the predictive variables studied were: age, sex, BUN, creatinine, hemoglobin, hematocrit, calcium and time on hemodialysis. The patients were divided in two groups: those with lesions and a control group without lesions. The comparison between the two groups was done using unpaired t-test for continual variables, X2 for dichotomous variables and p < 0.05 was considered as statistically significant. Thirty two patients (45%) had lesions in the upper gastrointestinal tract, in the esophagus: 17%, stomach 30% and duodenum: 23%. Age was the only predictive variables statistically significant for gastric lesions. We conclude that gastrointestinal lesions are frequent in patients with end stage renal failure. The gastric lesions were the most frequent and appeared in older patients. We recommend endoscopic studies in all end stage renal failure patients as part of the pre transplant evaluation. We also suggest endoscopy as follow up after transplantation.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Case-Control Studies ; Duodenal Ulcer/diagnosis ; Duodenal Ulcer/etiology ; Endoscopy, Gastrointestinal ; Female ; Humans ; Hyperemia/diagnosis ; Hyperemia/etiology ; Kidney Failure, Chronic/complications ; Male ; Middle Aged ; Purpura/diagnosis ; Purpura/etiology ; Renal Dialysis ; Retrospective Studies ; Stomach Ulcer/diagnosis ; Stomach Ulcer/etiology
    Language Spanish
    Publishing date 1994-01
    Publishing country Venezuela
    Document type English Abstract ; Journal Article
    ZDB-ID 731083-3
    ISSN 0016-3503
    ISSN 0016-3503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Lopinavir/ritonavir vs. indinavir/ritonavir in antiretroviral naive HIV-infected patients: immunovirological outcome and side effects.

    Bongiovanni, Marco / Bini, Teresa / Chiesa, Elisabetta / Cicconi, Paola / Adorni, Fulvio / Monforte d'Arminio, Antonella

    Antiviral research

    2004  Volume 62, Issue 1, Page(s) 53–56

    Abstract: We compared immunovirological outcomes and toxicities of HAART regimens including LPV/r and IDV/r in antiretroviral naïve HIV-1 patients. We retrospectively selected 55 patients starting LPV/r and 52 starting IDV/r as first-line HAART. Immunovirological ... ...

    Abstract We compared immunovirological outcomes and toxicities of HAART regimens including LPV/r and IDV/r in antiretroviral naïve HIV-1 patients. We retrospectively selected 55 patients starting LPV/r and 52 starting IDV/r as first-line HAART. Immunovirological and metabolic parameters were recorded at baseline and every 3 months as were side effects, AIDS-defining events and deaths. Demographic characteristics and NRTIs included in the regimens were comparable. Both groups reached undetectable HIV-RNA plasma viremia from third month and maintained during follow-up. However, patients receiving IDV/r had a lower probability to obtain virological success (RH: 0.46). Patients receiving IDV/r patients showed a greater increase of total cholesterol (P = 0.01). Three patients on LPV/r and 21 on IDV/r discontinued the drug for toxicity, leading to a 8.40 higher risk of discontinuation in the latter group. In our clinical setting IDV/r showed to be less effective and more toxic than LPV/RTV as first-line HAART.
    MeSH term(s) Adult ; Antiretroviral Therapy, Highly Active/methods ; Cholesterol/blood ; Female ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV Infections/virology ; HIV Protease Inhibitors/administration & dosage ; HIV Protease Inhibitors/adverse effects ; HIV Protease Inhibitors/therapeutic use ; HIV-1/drug effects ; HIV-1/isolation & purification ; Humans ; Indinavir/administration & dosage ; Indinavir/adverse effects ; Indinavir/therapeutic use ; Lopinavir ; Male ; Pyrimidinones/administration & dosage ; Pyrimidinones/adverse effects ; Pyrimidinones/therapeutic use ; RNA, Viral/blood ; Retrospective Studies ; Ritonavir/administration & dosage ; Ritonavir/adverse effects ; Ritonavir/therapeutic use ; Viremia
    Chemical Substances HIV Protease Inhibitors ; Pyrimidinones ; RNA, Viral ; Lopinavir (2494G1JF75) ; Indinavir (5W6YA9PKKH) ; Cholesterol (97C5T2UQ7J) ; Ritonavir (O3J8G9O825)
    Language English
    Publishing date 2004-04
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 306628-9
    ISSN 1872-9096 ; 0166-3542
    ISSN (online) 1872-9096
    ISSN 0166-3542
    DOI 10.1016/j.antiviral.2003.12.002
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  10. Article: Transplant coordination program: a useful tool to improve organ donation in Venezuela.

    Milanés, Carmen Luisa / Gonzalez, Leyda / Hernández, Eddy / Arminio, Anabella / Clesca, Paul / Rivas-Vetencourt, Pedro A

    Progress in transplantation (Aliso Viejo, Calif.)

    2003  Volume 13, Issue 4, Page(s) 296–298

    Abstract: Donor shortage is the single most important limitation for allowing adequate growth of transplant programs. Transplant coordination programs have been shown to provide solutions to this situation worldwide. To evaluate the efficacy of transplant ... ...

    Abstract Donor shortage is the single most important limitation for allowing adequate growth of transplant programs. Transplant coordination programs have been shown to provide solutions to this situation worldwide. To evaluate the efficacy of transplant coordination programs in Venezuela, a pilot program was implemented at a 1200-bed teaching hospital. The implementation of this program included an assessment of the hospital's donation practices such as donor identification, maintenance, brain-death diagnosis, family consent for donation, and timely transport and allocation of organs and tissues. A follow-up 1 year after the implementation of the transplant coordination program demonstrated a 7-fold increase in the number of donors compared with the 2 previous years when the program did not exist. During the first year of application, the transplant coordination program resulted in solutions in how to address issues surrounding the procurement process in a hospital with a high potential donor rate; a linkage between the coordinator and the medical staff through educational activities; increased skills of hospital staff; and a methodology that should be applied extensively in hospitals with high donor potential to deal with the organ shortage.
    MeSH term(s) Humans ; Personnel, Hospital/education ; Program Evaluation ; Tissue and Organ Procurement ; Venezuela
    Language English
    Publishing date 2003-12
    Publishing country United States
    Document type Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2019786-X
    ISSN 1526-9248
    ISSN 1526-9248
    DOI 10.1177/152692480301300410
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