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  1. Article ; Online: A new class of high performance metal-fiber thermoplastic composites for additive manufacturing

    Mohanty, Debapriya Pinaki / Arnold, Brian J. / Baruah, Sweta / Chandrasekar, Srinivasan / Mann, James B.

    Composites Part A. 2023 June, v. 169 p.107519-

    2023  

    Abstract: The performance of a new class of metal fiber reinforced polymer (FRP) produced by additive manufacturing (AM) is discussed and compared with a commercially availablepolyethylene terephthalate glycol-PETG/carbon fiber composite. Aluminum alloy micro- ... ...

    Abstract The performance of a new class of metal fiber reinforced polymer (FRP) produced by additive manufacturing (AM) is discussed and compared with a commercially availablepolyethylene terephthalate glycol-PETG/carbon fiber composite. Aluminum alloy micro-fibers (Al6061-T6) produced by Modulation-Assisted Machining (MAM) are dispersed in a thermoplastic PETG matrix by screw extrusion. The filaments are feedstock for AM processing and sample preparation by fused deposition modeling (FDM). Mechanical testing, micro-hardness and wear testingprotocols were used to evaluate the performance of the new FRP.ThePETG/AlFRP composite samples show performance advantages over samples printed from commercially available PETG/carbon fiber filament.Computerized tomography (CT) and scanning electron microscopy (SEM) are used to explore the characteristics and distribution of the aluminum micro-fiber in the composite and the fracture surfaces in the test samples. AM processing with these new metal fiber/matrix formats enabled by MAM has unique potential to access high-performance composites applications.
    Keywords aluminum ; aluminum alloys ; carbon fibers ; electron microscopy ; extrusion ; feedstocks ; thermoplastics ; tomography ; 3D printing ; Micro-fiber ; Fiber reinforced polymer ; Modulation-Assisted Machining
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 2012223-8
    ISSN 1359-835X
    ISSN 1359-835X
    DOI 10.1016/j.compositesa.2023.107519
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data.

    Myers, Matthew A / Arnold, Brian J / Bansal, Vineet / Mullen, Katelyn M / Zaccaria, Simone / Raphael, Benjamin J

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Multi-region DNA sequencing of primary tumors and metastases from individual patients helps identify somatic aberrations driving cancer development. However, most methods to infer copy-number aberrations (CNAs) analyze individual samples. We introduce ... ...

    Abstract Multi-region DNA sequencing of primary tumors and metastases from individual patients helps identify somatic aberrations driving cancer development. However, most methods to infer copy-number aberrations (CNAs) analyze individual samples. We introduce HATCHet2 to identify haplotype- and clone-specific CNAs simultaneously from multiple bulk samples. HATCHet2 introduces a novel statistic, the mirrored haplotype B-allele frequency (mhBAF), to identify mirrored-subclonal CNAs having different numbers of copies of parental haplotypes in different tumor clones. HATCHet2 also has high accuracy in identifying focal CNAs and extends the earlier HATCHet method in several directions. We demonstrate HATCHet2's improved accuracy using simulations and a single-cell sequencing dataset. HATCHet2 analysis of 50 prostate cancer samples from 10 patients reveals previously-unreported mirrored-subclonal CNAs affecting cancer genes.
    Language English
    Publishing date 2023-07-15
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.07.13.548855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Horizontal gene transfer and adaptive evolution in bacteria.

    Arnold, Brian J / Huang, I-Ting / Hanage, William P

    Nature reviews. Microbiology

    2021  Volume 20, Issue 4, Page(s) 206–218

    Abstract: Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can considerably alter bacterial genomes, not all transfer events may be biologically ... ...

    Abstract Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can considerably alter bacterial genomes, not all transfer events may be biologically significant and may instead represent the outcome of an incessant evolutionary process that only occasionally has a beneficial purpose. When adaptive transfers occur, HGT and positive selection may result in specific, detectable signatures in genomes, such as gene-specific sweeps or increased transfer rates for genes that are ecologically relevant. In this Review, we first discuss the various mechanisms whereby HGT occurs, how the genetic signatures shape patterns of genomic variation and the distinct bioinformatic algorithms developed to detect these patterns. We then discuss the evolutionary theory behind HGT and positive selection in bacteria, and discuss the approaches developed over the past decade to detect transferred DNA that may be involved in adaptation to new environments.
    MeSH term(s) Bacteria/genetics ; Computational Biology ; Evolution, Molecular ; Gene Transfer, Horizontal ; Genome, Bacterial/genetics ; Genomics ; Phylogeny
    Language English
    Publishing date 2021-11-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2139054-X
    ISSN 1740-1534 ; 1740-1526
    ISSN (online) 1740-1534
    ISSN 1740-1526
    DOI 10.1038/s41579-021-00650-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5865: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 74: Show issues

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  4. Book: International tax primer

    Arnold, Brian J

    2016  

    Author's details Brian J. Arnold
    Keywords International business enterprises/Taxation/Law and legislation ; Internationales Steuerrecht ; Doppelbesteuerung ; Einkommensteuer ; Körperschaftsteuer ; Steuervermeidung ; Welt
    Language English
    Size xii, 230 Seiten
    Edition Third edition
    Publisher Kluwer Law International
    Publishing place Alphen aan den Rijn
    Document type Book
    ISBN 9789041159755 ; 9041159754
    Database ECONomics Information System

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  5. Article: Mapping the topography of spatial gene expression with interpretable deep learning.

    Chitra, Uthsav / Arnold, Brian J / Sarkar, Hirak / Ma, Cong / Lopez-Darwin, Sereno / Sanno, Kohei / Raphael, Benjamin J

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Spatially resolved transcriptomics technologies provide high-throughput measurements of gene expression in a tissue slice, but the sparsity of this data complicates the analysis of spatial gene expression patterns such as gene expression gradients. We ... ...

    Abstract Spatially resolved transcriptomics technologies provide high-throughput measurements of gene expression in a tissue slice, but the sparsity of this data complicates the analysis of spatial gene expression patterns such as gene expression gradients. We address these issues by deriving a
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.10.561757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Ivory poaching and the rapid evolution of tusklessness in African elephants.

    Campbell-Staton, Shane C / Arnold, Brian J / Gonçalves, Dominique / Granli, Petter / Poole, Joyce / Long, Ryan A / Pringle, Robert M

    Science (New York, N.Y.)

    2021  Volume 374, Issue 6566, Page(s) 483–487

    Abstract: Understanding the evolutionary consequences of wildlife exploitation is increasingly important as harvesting becomes more efficient. We examined the impacts of ivory poaching during the Mozambican Civil War (1977 to 1992) on the evolution of African ... ...

    Abstract Understanding the evolutionary consequences of wildlife exploitation is increasingly important as harvesting becomes more efficient. We examined the impacts of ivory poaching during the Mozambican Civil War (1977 to 1992) on the evolution of African savanna elephants (
    MeSH term(s) Amelogenin/genetics ; Animals ; Biological Evolution ; Crime ; Elephants/anatomy & histology ; Elephants/genetics ; Female ; Genes, X-Linked ; Heredity ; Male ; Metalloendopeptidases/genetics ; Selection, Genetic ; X Chromosome/genetics
    Chemical Substances Amelogenin ; Metalloendopeptidases (EC 3.4.24.-) ; meprin A (EC 3.4.24.18)
    Language English
    Publishing date 2021-10-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abe7389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

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  7. Article: The new services permanent establishment rule in the Canada-United States tax treaty

    Arnold, Brian J

    Globalization and its tax discontents : tax policy and international investments ; essays in honour of Alex Easson ; [This book draws from essays given at a symposium held in ... on 29 February 2008] , p. 280-304

    2010  , Page(s) 280–304

    Author's details Brian J. Arnold
    Keywords Globalisierung ; Dienstleistungshandel ; Steuerrecht ; Steuerpolitik ; Internationales Steuerrecht ; Internationales Abkommen ; USA ; Kanada
    Language English
    Publisher University of Toronto Press
    Publishing place Toronto [u.a.]
    Document type Article
    ISBN 0802099769 ; 9780802099761
    Database ECONomics Information System

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  8. Book: Reforming Canada's international tax system

    Arnold, Brian J

    toward coherence and simplicity

    (Canadian tax paper ; 111)

    2009  

    Institution Canadian Tax Foundation
    Author's details Brian J. Arnold
    Series title Canadian tax paper ; 111
    Keywords Corporations, Foreign/Taxation ; Double taxation/Treaties ; Income tax/Law and legislation ; Income tax/Foreign income ; Investments, Foreign/Taxation/Law and legislation ; Steuerpolitik ; Außensteuerrecht ; Auslandsvermögen ; Einkommensteuer ; Unternehmensbesteuerung ; Doppelbesteuerung ; Steuerreform ; Kanada
    Language English
    Size XV, 382 S.
    Publisher Canadian Tax Foundation
    Publishing place Toronto
    Document type Book
    ISBN 0888082258 ; 9780888082251
    Database ECONomics Information System

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  9. Article ; Online: Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae.

    Wadsworth, Crista B / Arnold, Brian J / Sater, Mohamad R Abdul / Grad, Yonatan H

    mBio

    2018  Volume 9, Issue 4

    Abstract: Mosaic interspecifically acquired alleles of the multiple transferable resistance ( ...

    Abstract Mosaic interspecifically acquired alleles of the multiple transferable resistance (
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Azithromycin/pharmacology ; Bacterial Proteins/genetics ; Drug Resistance, Bacterial/genetics ; Epistasis, Genetic ; Gene Expression Regulation, Bacterial ; Gonorrhea/microbiology ; Linkage Disequilibrium ; Membrane Proteins/genetics ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Mutation ; Neisseria gonorrhoeae/drug effects ; Neisseria gonorrhoeae/genetics ; Promoter Regions, Genetic ; Repressor Proteins/genetics ; Transformation, Bacterial
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins ; Membrane Proteins ; Membrane Transport Proteins ; MtrD protein, Neisseria gonorrhoeae ; Repressor Proteins ; mtrR protein, Neisseria gonorrhoeae (155359-99-2) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2018-08-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mBio.01419-18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Conference proceedings ; Audio / Video: Limits on the use of low-tax regimes by multinational businesses

    Arnold, Brian J

    current measures and emerging trends = Limites à l'usage des régimes à fiscalité priviligiée par les entreprises multinationales = Beschränkungen der Nutzung von Niedrigsteuersystemen durch multinationale Unternehmen

    (Cahiers de droit fiscal international ; 86b)

    2004  

    Title variant Beschränkungen der Nutzung von Niedrigsteuersystemen durch multinationale Unternehmen ; Limites à l'usage des régimes à fiscalité priviligiée par les entreprises multinationales
    Institution International Fiscal Association
    Event/congress Congress of the International Fiscal Association (55, 2001.09.30-05.10, SanFranciscoCalif.)
    Author's details [55th congress of the International Fiscal Association, San Francisco, 2001]. General reporters: Brian J. Arnold
    Series title Cahiers de droit fiscal international ; 86b
    Keywords Multinationales Unternehmen ; Steueroase ; Steuervermeidung ; Steuerwettbewerb ; Doppelbesteuerung ; Außensteuerrecht ; Internationales Steuerrecht ; Welt
    Language English ; French ; German ; Spanish
    Size 1 CD-ROM, 12 cm
    Edition [Elektronische Ressource]
    Publisher Kluwer Law Internat
    Publishing place The Hague u.a.
    Document type Book ; Conference proceedings ; Audio / Video
    Note Beitr. teilw. dt., teilw. engl., teilw. franz. - Generalbericht und Zsfassungen der Beitr. in dt., engl., franz. und span. Sprache. - Enth. 31 Beitr.
    ISBN 9041116370 ; 9789041116376
    Database ECONomics Information System

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