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  1. Article ; Online: Vascular graft infections caused by

    Arsuffi, Stefania / Cambianica, Anna / Di Filippo, Elisa / Ripamonti, Diego / Tebaldi, Alessandra / Arosio, Marco Enrico Giovanni / Farina, Claudio Francesco / Rizzi, Marco

    Journal of clinical tuberculosis and other mycobacterial diseases

    2023  Volume 31, Page(s) 100360

    Abstract: Bacillus Calmette-Guerin (BCG) immunotherapy (i.e., intravesical instillation of live attenuated strain ... ...

    Abstract Bacillus Calmette-Guerin (BCG) immunotherapy (i.e., intravesical instillation of live attenuated strain of
    Language English
    Publishing date 2023-03-08
    Publishing country England
    Document type Case Reports
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2023.100360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: RNAscope in situ hybridization and RT-PCR for detection of SARS-CoV-2 in chilblain-like lesions: A clinical, laboratory and histopathological study.

    Robustelli Test, Elisa / Sena, Paolo / Locatelli, Andrea Gustavo / Carugno, Andrea / di Mercurio, Marco / Moggio, Erica / Gambini, Daniele Mario / Arosio, Marco Enrico Giovanni / Callegaro, Annapaola / Morotti, Denise / Gianatti, Andrea / Vezzoli, Pamela

    Pediatric dermatology

    2022  Volume 39, Issue 1, Page(s) 77–83

    Abstract: Background: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, an increasing number of chilblain-like lesions (ChLL) have been increasingly reported worldwide. To date, the causal link between ChLL and SARS-CoV-2 infection has not ... ...

    Abstract Background: Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, an increasing number of chilblain-like lesions (ChLL) have been increasingly reported worldwide. To date, the causal link between ChLL and SARS-CoV-2 infection has not been unequivocally established.
    Methods: In this case series, we present demographic, clinical, laboratory, and histopathological information regarding 27 young patients with a clinical diagnosis of ChLL who referred to the Dermatology Unit of Papa Giovanni XXIII Hospital, Bergamo, Italy, from 1 April 2020 to 1 June 2020.
    Results: The mean age was 14.2 years, and 21 patients (78%) experienced mild systemic symptoms a median of 28 days before the onset of cutaneous lesions. ChLL mostly involved the feet (20 patients - 74%). Among acral lesions, we identified three different clinical patterns: (i) chilblains in 20 patients (74%); (ii) fixed erythematous macules in 4 children (15%); (iii) erythrocyanosis in 3 female patients (11%). Blood examinations and viral serologies, including parvovirus B19, cytomegalovirus (CMV), Epstein-Barr virus (EBV), and coxsackievirus were normal in all. Three patients (11%) underwent nasopharyngeal swab for RT-PCR for SARS-CoV-2 showing only 1 positive. Histopathological examinations of 7 skin biopsies confirmed the clinical diagnosis of chilblains; vessel thrombi were observed only in 1 case. Our findings failed to demonstrate the direct presence of SARS-CoV-2 RNA in skin biopsies, both with real-time polymerase chain reaction (RT-PCR) and RNAscope in situ hybridization (ISH).
    Limitations: Limited number of cases, unavailability of laboratory confirmation of COVID-19 in all patients, potential methodological weakness, and latency of skin biopsies in comparison to cutaneous lesions onset.
    Conclusions: These observations may support the hypothesis of an inflammatory pathogenesis rather than the presence of peripheral viral particles. Although, we could not exclude an early phase of viral endothelial damage followed by an IFN-I or complement-mediated inflammatory phase. Further observations on a large number of patients are needed to confirm this hypothesis.
    MeSH term(s) Adolescent ; COVID-19 ; Chilblains/diagnosis ; Child ; Epstein-Barr Virus Infections ; Female ; Herpesvirus 4, Human ; Humans ; In Situ Hybridization ; Laboratories ; RNA, Viral ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2022-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1882: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Coronavirus disease 2019 (COVID-19) rash in a psoriatic patient treated with Secukinumab: Is there a role for Interleukin 17?

    Carugno, Andrea / Gambini, Daniele Mario / Raponi, Francesca / Vezzoli, Pamela / Robustelli Test, Elisa / Arosio, Marco Enrico Giovanni / Callegaro, Annapaola / Sena, Paolo

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14011

    MeSH term(s) Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antibodies, Monoclonal, Humanized/adverse effects ; COVID-19/diagnosis ; COVID-19/immunology ; COVID-19/virology ; Dermatologic Agents/administration & dosage ; Dermatologic Agents/adverse effects ; Drug Administration Schedule ; Exanthema/diagnosis ; Exanthema/immunology ; Exanthema/virology ; Host-Pathogen Interactions ; Humans ; Male ; Psoriasis/diagnosis ; Psoriasis/drug therapy ; Psoriasis/immunology ; SARS Virus/immunology ; SARS Virus/pathogenicity
    Chemical Substances Antibodies, Monoclonal, Humanized ; Dermatologic Agents ; secukinumab (DLG4EML025)
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5181: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Coronavirus disease 2019 (COVID-19) rash in a psoriatic patient treated with Secukinumab: Is there a role for Interleukin 17?

    Carugno, Andrea / Gambini, Daniele Mario / Raponi, Francesca / Vezzoli, Pamela / Robustelli Test, Elisa / Arosio, Marco Enrico Giovanni / Callegaro, Annapaola / Sena, Paolo

    Dermatol Ther

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #638701
    Database COVID19

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  5. Article ; Online: Coronavirus disease 2019 ( COVID ‐19) rash in a psoriatic patient treated with Secukinumab

    Carugno, Andrea / Gambini, Daniele Mario / Raponi, Francesca / Vezzoli, Pamela / Robustelli Test, Elisa / Arosio, Marco Enrico Giovanni / Callegaro, Annapaola / Sena, Paolo

    Dermatologic Therapy ; ISSN 1396-0296 1529-8019

    Is there a role for Interleukin 17?

    2020  

    Keywords Dermatology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/dth.14011
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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