Article: Risk factors for penile prosthesis infection: An umbrella review and meta-analysis.
2023 Volume 22, Issue 2, Page(s) 96–101
Abstract: Background: As available data on implantation-related infections is contradictory, the aim was to identify the predictors of penile prosthesis infection.: Methods: We performed an umbrella review and meta-analysis including systematic reviews with ... ...
Abstract | Background: As available data on implantation-related infections is contradictory, the aim was to identify the predictors of penile prosthesis infection. Methods: We performed an umbrella review and meta-analysis including systematic reviews with extractable data. Literature search was done in two databases: PubMed and Google Scholar. The participants were males with erectile dysfunction regardless of etiology who underwent penile implant surgery. Using a standardized form, three trained researchers reviewed each reference (systematic review) by title and abstract. The meta-analysis was performed using Review Manager 5.4.1 (RevMan® 5.4.1). Results: A total of 78 systematic reviews were identified with the search strategies. Of these, 35 duplicates were removed. Thirty-seven full-text reviews were then excluded after revision. Six systematic reviews with a total of 271,226 patients (156,553 patients in the study group and 114,673 patients in the control group) were included in the meta-analysis. The analysis identified various predictors of adverse outcomes (infection). Among them were glycated hemoglobin (HbA1c) and different characteristics of penile implants. Conclusions: The systematic review and meta-analysis revealed significant risk factors/predictors of penile prosthesis infection: glycated hemoglobin levels; reoperation, and two predictors associated with the type of penile prosthesis. The weighted mean HbA1c levels of patients with and without infections were 8.37% and 7.17% respectively. The OR was as follows: first surgery/revision OR 0.36 (95% CI 0.29-0.45); antibiotic-coated/non-coated prosthesis OR 0.47 (95% CI 0.31-0.72); malleable/inflatable prosthesis OR 3.51 (95% CI 1.41-8.74). |
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Language | English |
Publishing date | 2023-07-29 |
Publishing country | United States |
Document type | Journal Article ; Review |
ZDB-ID | 2631788-6 |
ISSN | 2090-598X |
ISSN | 2090-598X |
DOI | 10.1080/2090598X.2023.2242204 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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