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  1. Article: Clinicopathological insights into an outbreak of foodborne botulism in Hamadan, Iran, in 2023: A microbiological and laboratory findings.

    Sadeghian, Zohre / Torkaman Asadi, Fatemeh

    SAGE open medicine

    2023  Volume 11, Page(s) 20503121231218888

    Abstract: Background and objective: Foodborne botulism is one of the potentially fatal forms of food poisoning, usually caused by ingestion of home-canned vegetables, fruits, and dairy and fish products. This study aimed to assess the frequency of signs and ... ...

    Abstract Background and objective: Foodborne botulism is one of the potentially fatal forms of food poisoning, usually caused by ingestion of home-canned vegetables, fruits, and dairy and fish products. This study aimed to assess the frequency of signs and symptoms in patients with botulism following the ingestion of homemade Doogh, a traditional milk-based beverage, in Hamadan, Iran in 2023. We also examined the general characteristics of the recruited patients.
    Methods: During an outbreak, 21 patients were referred to the hospital because of food poisoning. All patients had a history of consumption of Doogh. After careful physical examination, all of them were hospitalized. Botulism was suspected in all patients except for the first patient.
    Results: The mean age of admitted patients was 33.09 ± 18.44 years, with 23.80% being males and 76.20% females. Incubation period in our patients was 68 ± 28.48 h. Notable symptoms included diplopia (95.23%), nausea and vomiting (85.71%), blurred vision (80.95%), and dizziness (61.90%). The laboratory results were within the normal range. No deaths occurred in this patient cohort. Furthermore, botulinum spores were detected in Doogh samples collected from the outbreak, confirming the presence of Clostridium botulinum spores as a source of the outbreak.
    Conclusions: This study highlights that the initial manifestations of botulism predominantly involved ophthalmologic abnormalities in most patients. Additionally, symptoms such as nausea, vomiting, and dizziness may manifest in cases of foodborne botulism. Timely diagnosis and treatment of botulism following the consumption of homemade Doogh played a crucial role in achieving positive outcomes, with no fatalities recorded in this patient cohort.
    Language English
    Publishing date 2023-12-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2735399-0
    ISSN 2050-3121
    ISSN 2050-3121
    DOI 10.1177/20503121231218888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Systematic review of image segmentation using complex networks

    Rezaei, Amin / Asadi, Fatemeh

    2024  

    Abstract: This review presents various image segmentation methods using complex networks. Image segmentation is one of the important steps in image analysis as it helps analyze and understand complex images. At first, it has been tried to classify complex networks ...

    Abstract This review presents various image segmentation methods using complex networks. Image segmentation is one of the important steps in image analysis as it helps analyze and understand complex images. At first, it has been tried to classify complex networks based on how it being used in image segmentation. In computer vision and image processing applications, image segmentation is essential for analyzing complex images with irregular shapes, textures, or overlapping boundaries. Advanced algorithms make use of machine learning, clustering, edge detection, and region-growing techniques. Graph theory principles combined with community detection-based methods allow for more precise analysis and interpretation of complex images. Hybrid approaches combine multiple techniques for comprehensive, robust segmentation, improving results in computer vision and image processing tasks.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Publishing date 2024-01-05
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Conservative Management of Retroperitoneal Hematoma Expanded to Prerenal Space Due to Episiotomy in a Woman with Vaginal Delivery, a case report.

    Haddadi, Mohammad / Hantoushzadeh, Sedigheh / Pesikhani, Maryam Deldar / Asadi, Fatemeh / Amini, Sima / Ghaemi, Marjan

    International journal of surgery case reports

    2024  Volume 115, Page(s) 109318

    Abstract: Introduction: Episiotomy is a procedure during vaginal delivery to facilitate a safer delivery. However, it can also have complications including hemorrhage, perineal tears, infections, and vaginal hematoma which should be managed and monitored ... ...

    Abstract Introduction: Episiotomy is a procedure during vaginal delivery to facilitate a safer delivery. However, it can also have complications including hemorrhage, perineal tears, infections, and vaginal hematoma which should be managed and monitored carefully.
    Presentation of case: A 27-year-old woman with term pregnancy, had a normal vaginal delivery at 39 weeks of gestation, and a large episiotomy was performed due to the estimated neonate weight to prevent shoulder dystocia. She was complicated with a huge pelvic hematoma that was expanded to prerenal space.
    Discussion: This complication was managed by conservative therapy, including antibiotic therapy, intensive observation of the patient's situation, and follow-up with a CT scan after consulting with a radiologist. The huge hematoma was reduced.
    Conclusion: Noninvasive management and close monitoring for pelvic hematoma due to episiotomy in a low-risk patient are successful; however, consulting with radiologists and experts and a multidisciplinary approach should be considered.
    Language English
    Publishing date 2024-01-27
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2024.109318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Anti-aging effects of the pistachio extract on mesenchymal stem cells proliferation and telomerase activity.

    Askari, Nahid / Asadi, Fatemeh / Nazer, Atefeh / Falahati-Pour, Soudeh Khanamani

    Archives of gerontology and geriatrics

    2023  Volume 111, Page(s) 105016

    Abstract: Purpose: Using mesenchymal stem cells (MSCs) is a promising method in regenerative medicine. Limited proliferation and aging process of MSC are the most common problems in MSCs application. In the present study, we intend to investigate the anti-aging ... ...

    Abstract Purpose: Using mesenchymal stem cells (MSCs) is a promising method in regenerative medicine. Limited proliferation and aging process of MSC are the most common problems in MSCs application. In the present study, we intend to investigate the anti-aging properties of pistachio pericarp in bone marrow-derived MSCs of old male rats.
    Materials and methods: First, 1000, 2000, and 3000 µg/mL AEPP were used to treat MSCs derived from bone marrow for 24 h at 37 °C. Then, cell viability, population doubling time, the percentage of senescent cells, telomere length, telomerase activity, and the expression of TRF1 and RAP1 when bone marrow-derived MSCs treated with AEPP were investigated.
    Results: The results showed that cell viability increased when MSCs derived from bone marrow were treated with 2000 and 3000 µg/mL AEPP, indicating this extract may stimulate proliferation. The population doubling time was also enhanced with an increase in AEPP concentration. Importantly, an increase in AEPP concentration significantly reduced senescent cell percentage. Telomere length, telomerase activity, and the expression of anti-aging genes were significantly increased with the increase of AEPP dose.
    Conclusion: Taken together, AEPP has been used as a natural compound with excellent proliferation and anti-aging ability in MSCs. As new therapeutic candidates with promising effects, it can be used with high safety by multiplying cells and delaying the aging process. However, more studies are needed and the anti-aging effects of this extract should be well confirmed in animal models and clinical trials.
    MeSH term(s) Male ; Humans ; Rats ; Animals ; Telomerase/genetics ; Telomerase/metabolism ; Pistacia/metabolism ; Aging ; Mesenchymal Stem Cells/metabolism ; Cell Proliferation ; Cell Differentiation
    Chemical Substances Telomerase (EC 2.7.7.49)
    Language English
    Publishing date 2023-04-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 603162-6
    ISSN 1872-6976 ; 0167-4943
    ISSN (online) 1872-6976
    ISSN 0167-4943
    DOI 10.1016/j.archger.2023.105016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Validation of the Persian version of the Perinatal Anxiety Screening Scale (PASS) among antenatal and postnatal women.

    Amiri, Parastoo / Bahaadinbeigy, Kambiz / Asadi, Fatemeh / Rahmati, Shoboo / Mazhari, Shahrzad

    BMC pregnancy and childbirth

    2022  Volume 22, Issue 1, Page(s) 883

    Abstract: Background: Anxiety disorder is more common in women than men. To some extent, it can be attributed to childbirth and factors related to pregnancy in women. Therefore, it is necessary for mothers to use valid and reliable scale to assess perinatal ... ...

    Abstract Background: Anxiety disorder is more common in women than men. To some extent, it can be attributed to childbirth and factors related to pregnancy in women. Therefore, it is necessary for mothers to use valid and reliable scale to assess perinatal anxiety, such as the perinatal anxiety screening scale (PASS). The purpose of this study was to investigate the validity and reliability of the PASS in Persian language.
    Methods: The PASS was translated into Persian (PASS-IR). Generally, 224 women antenatal and 125 postnatal answered the questions of PASS, EPDS-10, BAI and DASS-21 questionnaires. The data was collected in the health centers of Kerman by random sampling method. Finally, content validity, factor analysis, internal consistency and test-retest reliability were evaluated.
    Results: The mean age of the participants was 32.89 years (range between 18 and 45 and SD = 6.23). More than half of the participating were at risk of severe anxiety (53.5%). Content Validity Index (CVI) and Content Validity Ratio (CVR) were 0.80 and 0.87. PASS-IR subscales include social anxiety and specific fears, general anxiety and adjustment, acute anxiety and trauma, and perfectionism and control. PASS-IR was significantly correlated with EPDS-10 (rho = 0.42), BAI (rho = 0.53), DASS-21 with three concepts of depression, anxiety and stress (rho = 0.51, rho = 0.49 and rho = 0.49), and adverse life events (rho = 0.30).
    Conclusion: The results of this study show that PASS-IR has good validity and reliability. Therefore, it can be used to screen for anxiety disorder among Iranian women in the perinatal stage.
    MeSH term(s) Pregnancy ; Male ; Female ; Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Language ; Reproducibility of Results ; Iran ; Anxiety/diagnosis ; Research Design
    Language English
    Publishing date 2022-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059869-5
    ISSN 1471-2393 ; 1471-2393
    ISSN (online) 1471-2393
    ISSN 1471-2393
    DOI 10.1186/s12884-022-05217-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The exo-microRNA (miRNA) signaling pathways in pathogenesis and treatment of stroke diseases: Emphasize on mesenchymal stem cells (MSCs).

    Farahmand, Yalda / Nabiuni, Mohsen / Vafaei Mastanabad, Mahsa / Sheibani, Mehrnaz / Mahmood, Bashar Shaker / Obayes, Ali Mohammed / Asadi, Fatemeh / Davallou, Rosa

    Cell biochemistry and function

    2024  Volume 42, Issue 2, Page(s) e3917

    Abstract: A major factor in long-term impairment is stroke. Patients with persistent stroke and severe functional disabilities have few therapy choices. Long noncoding RNAs (lncRNAs) may contribute to the regulation of the pathophysiologic processes of ischemic ... ...

    Abstract A major factor in long-term impairment is stroke. Patients with persistent stroke and severe functional disabilities have few therapy choices. Long noncoding RNAs (lncRNAs) may contribute to the regulation of the pathophysiologic processes of ischemic stroke as shown by altered expression of lncRNAs and microRNA (miRNAs) in blood samples of acute ischemic stroke patients. On the other hand, multipotent mesenchymal stem cells (MSCs) increase neurogenesis, and angiogenesis, dampen neuroinflammation, and boost brain plasticity to improve functional recovery in experimental stroke models. MSCs can be procured from various sources such as the bone marrow, adipose tissue, and peripheral blood. Under the proper circumstances, MSCs can differentiate into a variety of mature cells, including neurons, astrocytes, and oligodendrocytes. Accordingly, the capability of MSCs to exert neuroprotection and also neurogenesis has recently attracted more attention. Nowadays, lncRNAs and miRNAs derived from MSCs have opened new avenues to alleviate stroke symptoms. Accordingly, in this review article, we examined various studies concerning the lncRNAs and miRNAs' role in stroke pathogenesis and delivered an overview of the therapeutic role of MSC-derived miRNAs and lncRNAs in stroke conditions.
    MeSH term(s) Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Ischemic Stroke/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Mesenchymal Stem Cells/metabolism ; Stroke/therapy ; Stroke/metabolism ; Signal Transduction ; Mesenchymal Stem Cell Transplantation
    Chemical Substances MicroRNAs ; RNA, Long Noncoding
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 283643-9
    ISSN 1099-0844 ; 0263-6484
    ISSN (online) 1099-0844
    ISSN 0263-6484
    DOI 10.1002/cbf.3917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Prediction of mortality risk and duration of hospitalization of COVID-19 patients with chronic comorbidities based on machine learning algorithms.

    Amiri, Parastoo / Montazeri, Mahdieh / Ghasemian, Fahimeh / Asadi, Fatemeh / Niksaz, Saeed / Sarafzadeh, Farhad / Khajouei, Reza

    Digital health

    2023  Volume 9, Page(s) 20552076231170493

    Abstract: Background: The severity of coronavirus (COVID-19) in patients with chronic comorbidities is much higher than in other patients, which can lead to their death. Machine learning (ML) algorithms as a potential solution for rapid and early clinical ... ...

    Abstract Background: The severity of coronavirus (COVID-19) in patients with chronic comorbidities is much higher than in other patients, which can lead to their death. Machine learning (ML) algorithms as a potential solution for rapid and early clinical evaluation of the severity of the disease can help in allocating and prioritizing resources to reduce mortality.
    Objective: The objective of this study was to predict the mortality risk and length of stay (LoS) of patients with COVID-19 and history of chronic comorbidities using ML algorithms.
    Methods: This retrospective study was conducted by reviewing the medical records of COVID-19 patients with a history of chronic comorbidities from March 2020 to January 2021 in Afzalipour Hospital in Kerman, Iran. The outcome of patients, hospitalization was recorded as discharge or death. The filtering technique used to score the features and well-known ML algorithms were applied to predict the risk of mortality and LoS of patients. Ensemble Learning methods is also used. To evaluate the performance of the models, different measures including F1, precision, recall, and accuracy were calculated. The TRIPOD guideline assessed transparent reporting.
    Results: This study was performed on 1291 patients, including 900 alive and 391 dead patients. Shortness of breath (53.6%), fever (30.1%), and cough (25.3%) were the three most common symptoms in patients. Diabetes mellitus(DM) (31.3%), hypertension (HTN) (27.3%), and ischemic heart disease (IHD) (14.2%) were the three most common chronic comorbidities of patients. Twenty-six important factors were extracted from each patient's record. Gradient boosting model with 84.15% accuracy was the best model for predicting mortality risk and multilayer perceptron (MLP) with rectified linear unit function (MSE = 38.96) was the best model for predicting the LoS. The most common chronic comorbidities among these patients were DM (31.3%), HTN (27.3%), and IHD (14.2%). The most important factors in predicting the risk of mortality were hyperlipidemia, diabetes, asthma, and cancer, and in predicting LoS was shortness of breath.
    Conclusion: The results of this study showed that the use of ML algorithms can be a good tool to predict the risk of mortality and LoS of patients with COVID-19 and chronic comorbidities based on physiological conditions, symptoms, and demographic information of patients. The Gradient boosting and MLP algorithms can quickly identify patients at risk of death or long-term hospitalization and notify physicians to do appropriate interventions.
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076231170493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus during the COVID-19 pandemic.

    Rezaee, Delsuz / Bakhtiari, Somaye / Jalilian, Farid Azizi / Doosti-Irani, Amin / Asadi, Fatemeh Torkaman / Ansari, Nastaran

    Archives of virology

    2023  Volume 168, Issue 2, Page(s) 53

    Abstract: The prevalence of coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus among referred patients in Hamadan province, Iran, from November 2, 2021, to January 30, 2022, was evaluated. Samples were obtained from ... ...

    Abstract The prevalence of coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus among referred patients in Hamadan province, Iran, from November 2, 2021, to January 30, 2022, was evaluated. Samples were obtained from 14,116 individuals with COVID-19 symptoms and screened for SARS-CoV-2 and influenza viruses using a multiplex real-time PCR panel assay. Of these patients, 14.19%, 17.11%, and 1.35% were infected with influenza virus, SARS-CoV-2, and both viruses, respectively. The majority of the coinfected patients were female outpatients aged 19-60 years.
    MeSH term(s) Humans ; Female ; Male ; COVID-19/epidemiology ; SARS-CoV-2 ; Coinfection/epidemiology ; Pandemics ; Orthomyxoviridae/genetics ; Influenza, Human
    Language English
    Publishing date 2023-01-07
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-022-05628-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus during the COVID-19 pandemic

    Rezaee, Delsuz / Bakhtiari, Somaye / Jalilian, Farid Azizi / Doosti-Irani, Amin / Asadi, Fatemeh Torkaman / Ansari, Nastaran

    Arch Virol. 2023 Feb., v. 168, no. 2 p.53-53

    2023  

    Abstract: The prevalence of coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus among referred patients in Hamadan province, Iran, from November 2, 2021, to January 30, 2022, was evaluated. Samples were obtained from ... ...

    Abstract The prevalence of coinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus among referred patients in Hamadan province, Iran, from November 2, 2021, to January 30, 2022, was evaluated. Samples were obtained from 14,116 individuals with COVID-19 symptoms and screened for SARS-CoV-2 and influenza viruses using a multiplex real-time PCR panel assay. Of these patients, 14.19%, 17.11%, and 1.35% were infected with influenza virus, SARS-CoV-2, and both viruses, respectively. The majority of the coinfected patients were female outpatients aged 19–60 years.
    Keywords COVID-19 infection ; Orthomyxoviridae ; Severe acute respiratory syndrome coronavirus 2 ; females ; influenza ; mixed infection ; quantitative polymerase chain reaction ; Iran
    Language English
    Dates of publication 2023-02
    Size p. 53.
    Publishing place Springer Vienna
    Document type Article ; Online
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-022-05628-y
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Assessment of the Relationship between Nurses' Perception of Ethical Climate and Job Burnout in Intensive Care Units.

    Rivaz, Mozhgan / Asadi, Fatemeh / Mansouri, Parisa

    Investigacion y educacion en enfermeria

    2020  Volume 38, Issue 3

    Abstract: Objectives: To determine the relationship between ethical climate and burnout in nurses working in Intensive Care Units (ICUs).: Methods: This cross-sectional and multi-center study was conducted among 212 nurses working in adult ICUs of six ... ...

    Abstract Objectives: To determine the relationship between ethical climate and burnout in nurses working in Intensive Care Units (ICUs).
    Methods: This cross-sectional and multi-center study was conducted among 212 nurses working in adult ICUs of six hospitals affiliated to Shiraz University of Medical Sciences, Iran in 2019. The participants were selected using systematic random sampling technique. Data was collected using valid instruments of Olson's Hospital Ethical Climate Survey (HECS) and Maslach Burnout Inventory (MBI).
    Results: Ethical climate was favorable (3.5±0.6). The intensity (32.2±12.4) and frequency (25.5±12.4) of burnout were high. Ethical climate had significant and inverse relationships with frequency of burnout (r =-0.23, p=0.001) and with intensity of burnout (r=-0.186, p=0.007). Ethical climate explained 5.9% of burnout. Statistically significant relationships were also found between these factors: age with ethical climate (p=0.001), work shifts with burnout (p=0.02), and gender and with intensity frequency of burnout in ICU nurses (p=0.038). The results of Spearman correlation coefficient showed significant and inverse relationships between ethical climate and job burnout (r=-0.243, p < 0.001).
    Conclusions: Nurses in ICUs perceived that ethical climate was favorable however, burnout was high. Therefore, burnout can be affected by many factors and it is necessary to support ICU nurses since they undertake difficult and complicated task. It is recommended to assess factors that increase burnout and adopt specific measures and approaches to relieve nursing burnout.
    MeSH term(s) Adult ; Burnout, Professional/diagnosis ; Burnout, Professional/epidemiology ; Burnout, Professional/etiology ; Burnout, Professional/psychology ; Critical Care Nursing/ethics ; Critical Care Nursing/organization & administration ; Cross-Sectional Studies ; Female ; Health Surveys ; Humans ; Intensive Care Units/ethics ; Intensive Care Units/organization & administration ; Iran ; Male ; Middle Aged ; Nurses/organization & administration ; Nurses/psychology ; Organizational Culture ; Psychological Tests ; Regression Analysis ; Risk Factors ; Social Perception
    Language English
    Publishing date 2020-12-17
    Publishing country Colombia
    Document type Journal Article ; Multicenter Study
    ZDB-ID 605989-2
    ISSN 2216-0280 ; 0120-5307
    ISSN (online) 2216-0280
    ISSN 0120-5307
    DOI 10.17533/udea.iee.v38n3e12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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