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  1. Article: Circadian variation in cognition: a comparative study between sleep-disturbed and healthy participants

    Aseem, Anam / Hussain, Mohammed Ejaz

    Biological rhythm research. 2021 Apr. 21, v. 52, no. 4

    2021  

    Abstract: Aims: To understand the circadian variation in cognition over the course of the day in sleep-disturbed (SD) participants and to compare the findings with healthy controls. Methods: Subjects were screened using Pittsburgh sleep quality index (PSQI), and a ...

    Abstract Aims: To understand the circadian variation in cognition over the course of the day in sleep-disturbed (SD) participants and to compare the findings with healthy controls. Methods: Subjects were screened using Pittsburgh sleep quality index (PSQI), and a total of 24 participants (12 SD and 12 controls) were recruited for the study. P300 was recorded five times a day (8 a.m., 11 a.m., 2 p.m., 5 p.m. and 8 p.m.) for all the participants in both the groups. Results: The results revealed significant variations in P300 wave in both the groups at different time points. The P300 amplitude at 5 p.m. was significantly higher than that at 8 a.m. and 11 a.m., and the lowest peak was recorded at 8 p.m. preceded by that at 2 p.m. for healthy participants. In SD subjects, the highest amplitude was recorded at 8 p.m., followed by 5 p.m., whereas the lowest deflection was recorded at 2 p.m. preceded by 11 a.m. and 8 a.m. Similarly, P300 latency showed the longest value at 8 a.m. followed by 2 p.m., and further followed by 8 p.m. Shortest latency was recorded at 5 p.m. in non-SD participants, whereas SD participants demonstrated a contrasting trend with the longest latency being recorded at 2 p.m., followed by 8 a.m. and 5 p.m. Shortest latency was observed at 8 p.m. preceded by 11 a.m. Conclusion: These results suggest that P300 characteristics vary along the span of the day between SD and non-SD participants. Clinical trial registry: CTRI/2019/05/019154
    Keywords circadian rhythm ; clinical trials ; cognition ; comparative study ; research ; sleep
    Language English
    Dates of publication 2021-0421
    Size p. 636-644.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-light
    ZDB-ID 1185065-6
    ISSN 1744-4179 ; 0929-1016
    ISSN (online) 1744-4179
    ISSN 0929-1016
    DOI 10.1080/09291016.2019.1627656
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Cranial electrostimulation improves slow wave sleep in collegiate population: a polysomnographic study.

    Aseem, Anam / Chaudhry, Neera / Hussain, Mohammed Ejaz

    Sleep science (Sao Paulo, Brazil)

    2022  Volume 15, Issue 1, Page(s) 88–94

    Abstract: Objective: Sleep disturbance is quite prevalent among students, which leads to deleterious consequences on health. Cranial electrostimulation (CES) has been speculated to entrain cortical slow waves; therefore, we investigated the efficacy of cranial ... ...

    Abstract Objective: Sleep disturbance is quite prevalent among students, which leads to deleterious consequences on health. Cranial electrostimulation (CES) has been speculated to entrain cortical slow waves; therefore, we investigated the efficacy of cranial electrostimulation to improve slow wave sleep in collegiates.
    Methods: Twenty-eight students with Pittsburgh sleep quality index (PSQI) score >5 were randomly assigned into two groups: CES and control. Participants in CES group completed 60 minutes of CES intervention for 12 weeks with 100 µA microcurrent and 0.5 Hz frequency parameters during night. Pre- and post-intervention measures were taken for sleep architecture using over-night polysomnography (PSG) and sleep quality using PSQI. Participants were instructed to report to the laboratory at 10:00 p.m. and PSG was performed with electroencephalograms (EEG), chin electromyography (EMG) and bilateral electrooculogram (EOG) in place. Sleep stages were scored manually in accordance with the new AASM guidelines. PSG variables reported in the present study are sleep latency (SL), total sleep time (TST), percentage of N1, N2, N3, NREM (non-rapid eye movement), REM (rapid eye movement) and sleep efficiency (SE%).
    Results: After ascertaining the comparability of demographic and sleep variables at baseline for both the groups, a 2X2 mixed model ANOVA was employed. Significant between-group differences were obtained for N1% and N3% such that N1% decreased and N3% increased post CES. However, other PSG variables, along with PSQI score did not demonstrate statistically significant between-group difference.
    Discussion: The present study demonstrated that 12-weeks of CES improved N3% and reduced N1%. Future researches should be undertaken to build upon the findings of present study.
    Language English
    Publishing date 2022-05-31
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2697016-8
    ISSN 1984-0063 ; 1984-0659
    ISSN (online) 1984-0063
    ISSN 1984-0659
    DOI 10.5935/1984-0063.20220029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sleep quality and its effect on event related potential P300 in adolescents with and without sleep disturbances.

    Aseem, Anam / Hussain, Mohammed Ejaz

    International journal of adolescent medicine and health

    2019  Volume 34, Issue 1

    Abstract: Objectives: The present study aimed: (i) to investigate the sleep quality and cortical arousal (ERP P300) in adolescents with and without sleep disturbances, and (ii) to examine whether P300 vary as a function of quality of the previous night's sleep in ...

    Abstract Objectives: The present study aimed: (i) to investigate the sleep quality and cortical arousal (ERP P300) in adolescents with and without sleep disturbances, and (ii) to examine whether P300 vary as a function of quality of the previous night's sleep in sleep disturbed adolescents and to compare the findings with healthy controls.
    Methods: Fifteen sleep disturbed adolescents and 15 age-matched controls were recruited. Participants filled 10 days of sleep logs to identify their good (GN) and bad nights (BN). GN and BN were scored as a measure of sleep efficiency (SE), with nights having greater SE defined as GN and nights with lower SE scores labelled as BN. Afterwards, subjects were summoned to the lab for recording ERP P300 once after a night of good sleep (GN) and once after a night of bad sleep (BN).
    Results: The findings demonstrate that sleep disturbed adolescents exhibited poorer quality of sleep than controls. The ERP P300 also revealed significant difference in participants with and without sleep disturbance. Moreover, the P300 amplitude was higher and the latency was shorter after a GN in sleep disturbed as well as in controls, however, the values were better for adolescents without disturbed sleep. Similarly, amplitude and latency of P300 was lower and longer, respectively, after a BN in both the groups, however, participants with sleep disturbance demonstrated very penurious scores for amplitude and latency than the controls.
    Conclusion: Adolescents with sleep disturbance have poorer sleep quality and ERP characteristics than their healthy counterparts. Moreover, the quality of the previous night sleep determines cortical arousal in both sleep disturbed and healthy controls.
    Language English
    Publishing date 2019-12-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639287-8
    ISSN 2191-0278 ; 0334-0139
    ISSN (online) 2191-0278
    ISSN 0334-0139
    DOI 10.1515/ijamh-2019-0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Cranial electrostimulation improves slow wave sleep in collegiate population: a polysomnographic study

    Aseem, Anam / Chaudhry, Neera / Hussain, Mohammed Ejaz

    Sleep Science

    2022  Volume 15, Issue 01, Page(s) 88–94

    Abstract: Objective: Sleep disturbance is quite prevalent among students, which leads to deleterious consequences on health. Cranial electrostimulation (CES) has been speculated to entrain cortical slow waves; therefore, we investigated the efficacy of cranial ... ...

    Abstract Objective: Sleep disturbance is quite prevalent among students, which leads to deleterious consequences on health. Cranial electrostimulation (CES) has been speculated to entrain cortical slow waves; therefore, we investigated the efficacy of cranial electrostimulation to improve slow wave sleep in collegiates.
    Methods: Twenty-eight students with Pittsburgh sleep quality index (PSQI) score >5 were randomly assigned into two groups: CES and control. Participants in CES group completed 60 minutes of CES intervention for 12 weeks with 100 μA microcurrent and 0.5 Hz frequency parameters during night. Pre- and post-intervention measures were taken for sleep architecture using over-night polysomnography (PSG) and sleep quality using PSQI. Participants were instructed to report to the laboratory at 10:00 p.m. and PSG was performed with electroencephalograms (EEG), chin electromyography (EMG) and bilateral electrooculogram (EOG) in place. Sleep stages were scored manually in accordance with the new AASM guidelines. PSG variables reported in the present study are sleep latency (SL), total sleep time (TST), percentage of N1, N2, N3, NREM (non-rapid eye movement), REM (rapid eye movement) and sleep efficiency (SE%).
    Results: After ascertaining the comparability of demographic and sleep variables at baseline for both the groups, a 2X2 mixed model ANOVA was employed. Significant between-group differences were obtained for N1% and N3% such that N1% decreased and N3% increased post CES. However, other PSG variables, along with PSQI score did not demonstrate statistically significant between-group difference.
    Discussion: The present study demonstrated that 12-weeks of CES improved N3% and reduced N1%. Future researches should be undertaken to build upon the findings of present study.
    Keywords Sleep ; Polysomnography ; Students ; Slow Wave Sleep
    Language English
    Publishing date 2022-03-01
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2697016-8
    ISSN 1984-0063 ; 1984-0659 ; 1984-0063
    ISSN (online) 1984-0063
    ISSN 1984-0659 ; 1984-0063
    DOI 10.5935/1984-0063.20220029
    Database Thieme publisher's database

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