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Article ; Online: The awareness of neglected tropical diseases in a sample of medical and nursing students in Cairo University, Egypt: A cross-sectional study.

Elfar, Eman / Asem, Noha / Yousof, Hanaa

2020 Volume 14, Issue 11, Page(s) e0008826

Abstract: Neglected tropical diseases (NTDs) are a group of chronic diseases affecting 1.2 billion people worldwide, with more burden in the developing communities. Improving awareness about NTDs is a powerful affordable long-term intervention for infection ... ...

Abstract	Neglected tropical diseases (NTDs) are a group of chronic diseases affecting 1.2 billion people worldwide, with more burden in the developing communities. Improving awareness about NTDs is a powerful affordable long-term intervention for infection control. In literature, there is a limited number of studies in the developing countries assessing the awareness of healthcare providers regarding these diseases. The present study aimed at assessing the awareness of a sample of Cairo University medical and nursing students regarding NTDs. A cross-sectional descriptive study was conducted on 184 medical and nursing students in Cairo University. An anonymous self-administered questionnaire in English language with an estimated completion time of 15 minutes was used for evaluation. It included question categories which cover the knowledge about NTDs and control measures as well as the willingness to participate in NTDs control activities. Content analysis was performed on the materials and specifications of the epidemiology course given to medical and nursing students. Out of the study participants, 26% knew the meaning of NTDs. The main source of their knowledge was social media followed by the epidemiology course. A percentage of 33% of the students agreed that NTDs are of public health importance in Egypt. Thirty four percent of the participants expressed their willingness to participate in control activities for NTDs. Comparing medical and nursing students, a higher percentage of the nursing students stated that NTDs are causing a public health problem in Egypt with a statistically significant difference (P value < 0.001), while a statistically significant higher percentage of medical students believed that the awareness level regarding NTDs in Egypt is low (P value = 0.002). Cairo University medical and nursing students in this study showed a gap in the level of knowledge regarding NTDs and their control activities which represents a great threat to the control of these diseases.
MeSH term(s)	Cross-Sectional Studies ; Egypt ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Infection Control ; Male ; Neglected Diseases ; Public Health ; Students, Medical/statistics & numerical data ; Students, Nursing/statistics & numerical data ; Surveys and Questionnaires ; Tropical Medicine/statistics & numerical data ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-11-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2429704-5
ISSN	1935-2735 ; 1935-2727
ISSN (online)	1935-2735
ISSN	1935-2727
DOI	10.1371/journal.pntd.0008826
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Assessment of health-related quality of life in Egyptian children and adolescents with congenital adrenal hyperplasia.

Musa, Noha / Asem, Noha / Basyony, Shaza / Fawaz, Lubna

Journal of pediatric endocrinology & metabolism : JPEM

2020 Volume 33, Issue 2, Page(s) 295–304

Abstract: Background Congenital adrenal hyperplasia (CAH) is a chronic disorder causing adrenal insufficiency and hyperandrogenism affecting the quality of life (QOL). The objective of the study was to assess the health-related QOL (HRQOL) in Egyptian children and ...

Abstract	Background Congenital adrenal hyperplasia (CAH) is a chronic disorder causing adrenal insufficiency and hyperandrogenism affecting the quality of life (QOL). The objective of the study was to assess the health-related QOL (HRQOL) in Egyptian children and adolescents with CAH and to identify factors affecting it. Methods This cross-sectional study included 200 CAH patients (with 21-hydroxylase deficiency [21-OHD]) who were assessed according to their age, sex, clinical phenotype, timing of genitoplasty, hospital admissions within the last year, compliance to treatment, regularity of follow-up, presence of complications and hormonal control. HRQOL was assessed using the World Health Organization (WHO)QOL-BREF questionnaire with four domains analyzed independently including physical, psychological, social and environmental domains, with higher scores indicating better QOL. Results The study included 140 females and 60 males with a mean age of 6.6 ± 4.5 years, and 88% were salt-wasting (SW). Older patients had significantly lower QOL scores (r = - 0.151, p = 0.033). The physical domain correlated significantly with the degree of virilization (r = - 0.491, p = 0.001) and frequency of hospitalization (r = - 0.495, p < 0.001). The psychological domain was affected by age (r = - 0.157, p = 0.026) and timing of genitoplasty (r = - 0.326, p = 0.001), while the social domain was affected by age (r = -0.277, p < 0.005) and pubertal stage (r = - 0.195, p = 0.006). Females had lower scores at the psychological domain (p < 0.001), whereas males had lower scores at the physical domain (p = 0.003). Salt-losing patients had lower scores at the physical domain (p = 0.001). Patients with good hormonal control had higher scores at the physical domain (p = 0.03). Genitoplasty affected both psychological and social domains (p = 0.003 and 0.01, respectively). Patients with hypertension and hirsutism had lower QOL scores (p < 0.05). Conclusions HRQOL was relatively more affected in CAH patients with older age, poor hormonal control, high frequency of hospital admissions and those who developed complications.
MeSH term(s)	Adolescent ; Adrenal Hyperplasia, Congenital/physiopathology ; Adrenal Hyperplasia, Congenital/psychology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Egypt ; Environment ; Female ; Follow-Up Studies ; Health Status Indicators ; Humans ; Infant ; Male ; Prognosis ; Quality of Life ; Socioeconomic Factors ; Surveys and Questionnaires
Language	English
Publishing date	2020-02-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1231070-0
ISSN	2191-0251 ; 0334-018X
ISSN (online)	2191-0251
ISSN	0334-018X
DOI	10.1515/jpem-2019-0345
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Article ; Online: Patient safety: knowledge, influence and attitude among physicians: an exploratory study.

Asem, Noha / Sabry, Hend Aly / Elfar, Eman

The Journal of the Egyptian Public Health Association

2019 Volume 94, Issue 1, Page(s) 22

Abstract: Background: Patient safety is regarded as a global problem by which both developed and developing worlds are affected. It is defined as avoidance and prevention of patient injuries or adverse events, which could result during health care delivery. This ... ...

Abstract	Background: Patient safety is regarded as a global problem by which both developed and developing worlds are affected. It is defined as avoidance and prevention of patient injuries or adverse events, which could result during health care delivery. This study aimed to identify physicians' knowledge, influence, and attitude toward patient's safety in the faculty of medicine, Cairo university. Materials and methods: A cross-sectional study was conducted on 187 postgraduate physicians of different specialties working in the faculty of medicine, Cairo University. Anonymous self-administered questionnaires were distributed. The questionnaire is one of a series of tools designed for evaluation of the pilot implementation of the World Health Organization patient safety curriculum for medical schools. Results: Calculated attitude score was relatively higher than influence, then knowledge score (median scores were 4.25, 3.1, and 2.5 respectively). There was no difference in knowledge, attitude, and influence scores by different personal characteristics as gender, specialty, workplace, graduation year except for higher influence score among physician who received inpatient safety training (p = 0.016). There was a weak positive significant correlation between knowledge and influence scores and between influence and attitude scores (r = 0.25, p = 0.002; r = 0.27, p < 0.001 respectively). Conclusion: Higher patient safety positive attitude than influence and knowledge is pinpointed in physicians of different specialties in the faculty of medicine, Cairo University. This raises the attention to the importance of implementation of continuing patient safety education programs.
Language	English
Publishing date	2019-09-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	604779-8
ISSN	2090-262X ; 0013-2446
ISSN (online)	2090-262X
ISSN	0013-2446
DOI	10.1186/s42506-019-0022-9
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Article ; Online: Perceived stigma and healthcare services in healthcare settings among people living with HIV in Egypt: a qualitative study.

Elsharkawy, Aisha / Salem, Marwa Rashad / Asem, Noha / Ibrahim, Walid Kamal / Ramadan, El Gharib / Abdelaziz, Mohamed Abdelgawad / Hashish, Alaa / Elsayed, Heba / Hassany, Mohamed

Transactions of the Royal Society of Tropical Medicine and Hygiene

2022 Volume 116, Issue 9, Page(s) 868–873

Abstract: Background: The researchers conducted the current study to explore the perspectives of people living with HIV (PLHIV) on HIV-related discrimination and the delivery of healthcare services in healthcare settings.: Methods: An exploratory study using a ...

Abstract	Background: The researchers conducted the current study to explore the perspectives of people living with HIV (PLHIV) on HIV-related discrimination and the delivery of healthcare services in healthcare settings. Methods: An exploratory study using a qualitative approach was conducted among 46 PLHIV who were seeking HIV counselling and treatment from two HIV centres in the Cairo governorate using a purposive sampling technique. Results: A thematic content analysis was used to examine the responses. Participants had a combination of positive and negative experiences. Some participants reported staff acceptance and friendliness towards HIV-positive patients on antiretroviral treatment. Most interviewees observed that staff took extra precautions when treating or caring for them. The majority stated that counselling about the effects of the treatment was inadequate and that testing was either too far from their homes or at overcrowded centres with long waiting times. All the interviewees recommended ongoing communication and HIV counselling skills for healthcare providers who are in contact with HIV patients. Conclusion: Most of the study participants were not satisfied with HIV services in the participating centres, as well as experiencing stigma. More investment in enhancing the quality of HIV service delivery and reinforcement of health worker competencies, mainly in HIV counselling, may improve satisfaction, bearing in mind HIV-related stigma in the centres involved.
MeSH term(s)	Delivery of Health Care ; Egypt/epidemiology ; HIV Infections/drug therapy ; Humans ; Qualitative Research ; Social Stigma
Language	English
Publishing date	2022-09-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	441375-1
ISSN	1878-3503 ; 0035-9203
ISSN (online)	1878-3503
ISSN	0035-9203
DOI	10.1093/trstmh/trac028
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Article: Predictors of Short-Term Outcome of Kasai Portoenterostomy for Biliary Atresia in Infants: a Single-Center Study.

Yassin, Noha Adel / El-Tagy, Gamal / Abdelhakeem, Omar Nagy / Asem, Noha / El-Karaksy, Hanaa

Pediatric gastroenterology, hepatology & nutrition

2020 Volume 23, Issue 3, Page(s) 266–275

Abstract: Purpose: The outcome predictors of Kasai portoenterostomy (KPE) for biliary atresia (BA) are controversial. This study aimed to identify possible short-term outcome predictors of KPE for BA in infants.: Methods: This retrospective study included ... ...

Abstract	Purpose: The outcome predictors of Kasai portoenterostomy (KPE) for biliary atresia (BA) are controversial. This study aimed to identify possible short-term outcome predictors of KPE for BA in infants. Methods: This retrospective study included infants with BA who underwent KPE between January 2015 and December 2017 and were followed up for at least 6 months after surgery at the Pediatric Hepatology Unit, Cairo University Pediatric Hospital, Egypt. The short-term outcome was jaundice clearance within 6 months following surgery. All data were compared between the jaundice free group and those with persistent jaundice to identify the predictors of jaundice clearance. Results: The study included 75 infants. The mean age at the time of surgery was 82.43±22.77 days (range, 37-150 days), and 28 (37.3%) infants cleared their jaundice within 6 months postoperative. Age at surgery did not significantly affect the outcome ( Conclusion: Jaundice clearance after KPE for BA can be predicted using preoperative AST and presence of bile plugs in liver biopsy.
Language	English
Publishing date	2020-05-13
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	3032413-0
ISSN	2234-8840 ; 2234-8646
ISSN (online)	2234-8840
ISSN	2234-8646
DOI	10.5223/pghn.2020.23.3.266
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Article ; Online: Estimation of COVID-19 burden in Egypt.

Hassany, Mohamed / Abdel-Razek, Wael / Asem, Noha / AbdAllah, Mohamed / Zaid, Hala

The Lancet. Infectious diseases

2020 Volume 20, Issue 8, Page(s) 896–897

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Egypt ; Humans ; Influenza A Virus, H1N1 Subtype ; Influenza, Human ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-04-27
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2061641-7
ISSN	1474-4457 ; 1473-3099
ISSN (online)	1474-4457
ISSN	1473-3099
DOI	10.1016/S1473-3099(20)30319-4
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Article ; Online: Pattern and determinants of COVID-19 infection and mortality across countries: An ecological study

Asem, Noha / Ramadan, Ahmed / Hassany, Mohamed / Ghazy, Ramy Mohamed / Abdallah, Mohamed / Ibrahim, Mohamed / Gamal, Eman M. / Hassan, Shaimaa / Kamal, Nehal / Zaid, Hala

Heliyon. 2021 July, v. 7, no. 7 p.e07504-

2021

Abstract: This work aimed to identify the mathematical model and ecological determinants of COVID-19 infection and mortality across different countries during the first six months of the pandemic. In this study, authors used the online available data sources of ... ...

Abstract	This work aimed to identify the mathematical model and ecological determinants of COVID-19 infection and mortality across different countries during the first six months of the pandemic. In this study, authors used the online available data sources of randomly selected 18 countries to figure out potential determinants of COVID-19 transmissibility and mortality. The studied variables were environmental factors (daily average temperature, daily humidity), socioeconomic attributes (population age structure, count and density, human development index, per capita income (PCI), gross domestic product, internet coverage) mobility trends and chronic diseases. Researchers used the linear and exponential time series analysis, and further utilized multivariate techniques to explain the variance in the monthly increase in cases and deaths. In the first two months, the R² of linear models for the cases and deaths were higher than that of the corresponding R² of the exponential model. Later one, R² of the exponential model was occasionally relatively higher than that of the linear model. The exponential growth rate of new cases was significantly associated with mobility trends (β = 0.00398, P = 0.002), temperature (β = 0.000679, P = 0.011), humidity (β = 0.000249, P < 0.001), and the proportion of population aged ≥65 years (β = -0.000959, P = 0.012). Similarly, the exponential growth rate of deaths was significantly associated with mobility trends (β = 0.0027, P = 0.049), temperature (β = 0.0014, P < 0.001), humidity (β = -0.0026, P < 0.001), and PCI of countries. During this period, COVID-19 transmissibility was evident to be controlled as soon as social mobility is decreased by about 40% of the baseline over 3 months controlling for the other predictors. Controlling of COVID-19 pandemic is based mainly on controlling social mobility. Role of environmental determinants like temperature and humidity was well noticed on disease fatality and transmissibility. Socio-demographic determinants of COVID-19 spread and fatality included modifiable risk factors like PCI and non-modifiable risk factors like ageing.
Keywords	COVID-19 infection ; Internet ; age structure ; death ; ecological studies ; gross domestic product ; human development ; humidity ; income ; linear models ; mortality ; pandemic ; risk ; social mobility ; temperature ; time series analysis ; variance ; Ecological factors ; COVID-19 mortality ; COVID-19 transmissibility ; Exponential model ; Linear model ; COVID-19 incidence ; COVID-19
Language	English
Dates of publication	2021-07
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e07504
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Hepatocellular Carcinoma Multidisciplinary Clinic-Cairo University (HMC-CU) score: A new simple score for diagnosis of HCC.

Abdelaziz, Ashraf Omar / Nabil, Mohamed Mahmoud / Omran, Dalia Abdelhamid / Abdelmaksoud, Ahmed Hosni / Asem, Noha / Shousha, Hend Ibrahim / Elbaz, Tamer Mahmoud / Leithy, Rania

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

2020 Volume 21, Issue 2, Page(s) 102–105

Abstract: Background and study aims: The risk of hepatocarcinogenesis depends on background liver factors, of which fibrosis is a major determinant. Serum markers and scores are of increasing importance in non-invasive diagnosis of hepatic fibrosis. Our aim was ... ...

Abstract	Background and study aims: The risk of hepatocarcinogenesis depends on background liver factors, of which fibrosis is a major determinant. Serum markers and scores are of increasing importance in non-invasive diagnosis of hepatic fibrosis. Our aim was to predict the occurrence of hepatocellular carcinoma (HCC) using a non-invasive fibrosis score calculated using routine patient data. Patients and mthods: Our retrospective study included 1,291 hepatitis C related-HCC Egyptian patients (Group 1) recruited from the multidisciplinary HCC clinic, Faculty of Medicine, Cairo University in the period between February 2009 and June 2016 and 1072 chronic hepatitis C-naïve patients (Group 2) with advanced fibrosis (≥F3) and cirrhosis (F4). King score, Fibro Q score, Aspartate aminotransferase-to-platelet ratio index (APRI), AST to ALT ratio (AAR), LOK score, Göteborg University Cirrhosis Index (GUCI), Fibro-α and Biotechnology Research Center (BRC) scores were calculated for all patients. Regression analysis and receiver operating characteristics (ROC) were used to calculate the sensitivity, specificity and predictive values for significant scores with the best cut-off for predicting HCC. A regression equation was used to calculate predicted probabilities of HCC using the following variables; age, gender, haemoglobin, international normalised ratio (INR), albumin and alpha fetoprotein. The appropriate score cut-off points yielding optimal sensitivity and specificity were determined by ROC curve analysis. Results: There was a highly significant difference between the two groups for all calculated scores (P = 0.0001). Our new score, the Hepatocellular Carcinoma Multidisciplinary Clinic-Cairo University (HMC-CU) score (Logit probability of HCC = - 2.524 + 0.152age - 0.121Hb - 0.696INR - 1.059Alb + 0.022AFP + 0.976Sex. Male = 1, Female = 0), with a cut-off of 0.559 was superior to other scores for predicting HCC, having a sensitivity of 90% and specificity of 80.6%. Conclusion: The HMC-CU score is a promising, easily calculated, accurate, cost-effective score for HCC prediction in chronic HCV patients with advanced liver fibrosis.
MeSH term(s)	Age Factors ; Biomarkers/blood ; Carcinoma, Hepatocellular/blood ; Carcinoma, Hepatocellular/diagnosis ; Early Detection of Cancer/methods ; Female ; Hemoglobins/analysis ; Hepatitis C/complications ; Hepatitis C/diagnosis ; Hepatitis C/metabolism ; Humans ; International Normalized Ratio ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/metabolism ; Liver Neoplasms/blood ; Liver Neoplasms/diagnosis ; Male ; Middle Aged ; Predictive Value of Tests ; Research Design ; Serum Albumin/analysis ; Sex Factors ; alpha-Fetoproteins/analysis
Chemical Substances	Biomarkers ; Hemoglobins ; Serum Albumin ; alpha-Fetoproteins
Language	English
Publishing date	2020-05-18
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2502114-X
ISSN	2090-2387 ; 1687-1979
ISSN (online)	2090-2387
ISSN	1687-1979
DOI	10.1016/j.ajg.2020.04.001
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Article: Estimation of COVID-19 burden in Egypt

Hassany, Mohamed / Abdel-Razek, Wael / Asem, Noha / AbdAllah, Mohamed / Zaid, Hala

Lancet Infect Dis

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #712060
Database	COVID19

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Article ; Online: Estimation of COVID-19 burden in Egypt

Hassany, Mohamed / Abdel-Razek, Wael / Asem, Noha / AbdAllah, Mohamed / Zaid, Hala

The Lancet Infectious Diseases

2020 Volume 20, Issue 8, Page(s) 896–897

Keywords	Infectious Diseases ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	2061641-7
ISSN	1474-4457 ; 1473-3099
ISSN (online)	1474-4457
ISSN	1473-3099
DOI	10.1016/s1473-3099(20)30319-4
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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