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  1. Article ; Online: Survival analysis and identification of prognostic factors in colorectal liver metastasis after liver resection.

    Plúa-Muñiz, Katherine / Bailón-Cuadrado, Martín / Pérez-Saborido, Baltasar / Pacheco-Sánchez, David / Pinto, Pilar / Asensio-Díaz, Enrique

    Cirugia espanola

    2022  Volume 101, Issue 3, Page(s) 160–169

    Abstract: Introduction: Liver resection is the only curative treatment for colorectal liver metastasis. The identification of predictive factors leads to personalize patient management to enhance their long-term outcomes. This population-based study aimed to ... ...

    Abstract Introduction: Liver resection is the only curative treatment for colorectal liver metastasis. The identification of predictive factors leads to personalize patient management to enhance their long-term outcomes. This population-based study aimed to characterize factors associated with, and survival impact of patients who received hepatectomy for colorectal liver metastasis.
    Methods: A retrospective cohort study of all the hepatectomies for colorectal liver metastasis performed at third-level hospital of Spain (2010-2018) was conducted. The Kaplan-Meier method was used for survival analyses. Multivariable Cox and regression models were used to determine prognostic factors associated with overall survival.
    Results: The 5-year overall survival and disease-free survival were 42 and 33%, respectively. Survival analysis showed that metastasis features (number, largest size, distribution, and extrahepatic disease) and postsurgical factors (transfusion, major complications, and positive margin resection), as well as non-mutated KRAS, showed a significant association with survival. Otherwise, on multivariate analysis, only 5 independent risk factors were identified: major size metastasis >4 cm, RAS mutation, positive margin resection, intraoperative transfusion, and major complications.
    Conclusions: According to our findings, major size metastasis >4 cm, intraoperative transfusion, and major postoperative complications continue to be traditional prognostic factors. Meanwhile, the KRAS biomarker has a powerful impact as a survival prognostic factor.
    MeSH term(s) Humans ; Prognosis ; Hepatectomy/methods ; Retrospective Studies ; Proto-Oncogene Proteins p21(ras) ; Liver Neoplasms/secondary ; Survival Analysis ; Colorectal Neoplasms/surgery
    Chemical Substances Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
    Language English
    Publishing date 2022-09-12
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2022.09.023
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  2. Article ; Online: Embolismo pulmonar por fistulización de quiste hidatídico hepático a vena cava inferior.

    Bailón-Cuadrado, Martín / Barrera-Rebollo, Asterio / Pérez-Saborido, Baltasar / Asensio-Díaz, Enrique

    Enfermedades infecciosas y microbiologia clinica

    2015  Volume 33, Issue 8, Page(s) 572

    Title translation Pulmonary embolism due to a liver hydatid cyst fistulized into the inferior cava vein.
    MeSH term(s) Albendazole/therapeutic use ; Anaphylaxis/etiology ; Anthelmintics/therapeutic use ; Blood Vessel Prosthesis Implantation ; Combined Modality Therapy ; Digestive System Fistula/etiology ; Digestive System Fistula/surgery ; Echinococcosis, Hepatic/complications ; Echinococcosis, Hepatic/diagnostic imaging ; Echinococcosis, Hepatic/drug therapy ; Echinococcosis, Hepatic/surgery ; Emergencies ; Humans ; Male ; Middle Aged ; Pulmonary Embolism/etiology ; Rupture, Spontaneous ; Vascular Fistula/etiology ; Vascular Fistula/surgery ; Vena Cava, Inferior/pathology ; Vena Cava, Inferior/surgery
    Chemical Substances Anthelmintics ; Albendazole (F4216019LN)
    Language Spanish
    Publishing date 2015-10
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2015.02.009
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    Zs.A 3204: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Intraductal papillary neoplasia of the bile duct with malignancy: a differentiated entity of cholangiocarcinoma with a better prognosis. A review of three new cases.

    Pérez Saborido, Baltasar / Bailón Cuadrado, Martín / Rodríguez López, Mario / Asensio Díaz, Enrique / Madrigal Rubiales, Beatriz / Barrera Rebollo, Asterio

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2017  Volume 109, Issue 8, Page(s) 592–595

    Abstract: Introduction: Intraductal papillary neoplasms of the bile duct have been recognized as a differentiated entity to other biliary tumors since 2001. They are characterized by intraductal growth, with or without mucus production, and have malignant ... ...

    Abstract Introduction: Intraductal papillary neoplasms of the bile duct have been recognized as a differentiated entity to other biliary tumors since 2001. They are characterized by intraductal growth, with or without mucus production, and have malignant potential, although they have a better prognosis than other types of cholangiocarcinoma.
    Case reports: From January 2010 to August 2015, we included three patients with a confirmed diagnosis of bile duct intraductal papillary neoplasia with malignancy that were treated at our center. Two cases were male and one female with a mean age of 67.3 years. All three patients presented malignancy at the time of diagnosis. One patient was asymptomatic and the diagnosis was reported in the hepatectomy specimen after a liver transplant due to autoimmune hepatitis. The other two patients presented with cholestasis and acute cholangitis and the diagnosis was made based on imaging tests (computed tomography [CT] and magnetic resonance imaging [MRI]) and endoscopic retrograde cholangiopancreatography (ERCP) with brushing and a biopsy. The treatment in both cases was surgical with a left hepatectomy, and resection of the left bile duct and segment I. They did not receive adjuvant treatment. None of the cases had recurrence of the disease.
    Discussion: Malignant intraductal papillary neoplasias of the biliary tract represent a different entity of cholangiocarcinoma with a better prognosis. Its diagnosis is based on imaging tests and histology by ERCP. The treatment is surgical, achieving a high rate of success with a low relapse rate.
    Language English
    Publishing date 2017-08
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2017.4835/2016
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    Zs.B 199: Show issues Location:
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  4. Article: Preoperative pancreatic resection score: a preliminary prospective validation from Spain.

    Rodriguez-Lopez, Mario / Bailon-Cuadrado, Martin / Tejero-Pintor, Francisco J / Perez-Saborido, Baltasar / Asensio-Diaz, Enrique / Barrera-Rebollo, Asterio

    Hepatobiliary & pancreatic diseases international : HBPD INT

    2016  Volume 15, Issue 6, Page(s) 667–668

    MeSH term(s) Aged ; Biliary Tract Diseases/diagnosis ; Biliary Tract Diseases/mortality ; Biliary Tract Diseases/surgery ; Decision Support Techniques ; Female ; Humans ; Male ; Middle Aged ; Pancreatectomy/adverse effects ; Pancreatectomy/mortality ; Pancreatic Diseases/diagnosis ; Pancreatic Diseases/mortality ; Pancreatic Diseases/surgery ; Postoperative Complications/etiology ; Postoperative Complications/mortality ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Risk Assessment ; Risk Factors ; Spain ; Treatment Outcome
    Language English
    Publishing date 2016-12-01
    Publishing country Singapore
    Document type Letter ; Observational Study ; Validation Studies
    ZDB-ID 2241386-8
    ISSN 1499-3872
    ISSN 1499-3872
    DOI 10.1016/s1499-3872(16)60151-0
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    Zs.A 6313: Show issues Location:
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  5. Article ; Online: Incarcerated Recurrent Amyand's Hernia: Inguinal Herniorraphy and Laparoscopic Inspection.

    Bailon-Cuadrado, Martin / Perez-Saborido, Baltasar / Asensio-Diaz, Enrique / Blanco-Alvarez, Jose I / Rodriguez-Lopez, Mario

    Surgical infections

    2016  Volume 17, Issue 2, Page(s) 264–265

    MeSH term(s) Aged, 80 and over ; Appendicitis/diagnosis ; Appendicitis/surgery ; Hernia/complications ; Hernia/diagnosis ; Hernia/therapy ; Herniorrhaphy/methods ; Humans ; Laparoscopy/methods ; Male ; Recurrence
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1440120-4
    ISSN 1557-8674 ; 1096-2964
    ISSN (online) 1557-8674
    ISSN 1096-2964
    DOI 10.1089/sur.2015.157
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    Zs.A 5617: Show issues Location:
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  6. Article: Graft versus host disease as a complication after liver transplantation: A rare but serious association.

    Pérez-Saborido, Baltasar / Asensio-Díaz, Enrique / Barrera-Rebollo, Asterio / Rodríguez-López, Mario / Gonzalo-Martín, Marta / Madrigal-Rubiales, Beatriz / García-Pajares, Félix / Pacheco-Sánchez, David

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2016  Volume 108, Issue 1, Page(s) 49–50

    Abstract: Unlabelled: The graft versus host disease after liver transplant is rare, with an incidence less than 1%, but with a high mortality (75-85%), especially due to infectious complications. It usually affects gastrointestinal tract, skin and blood system in ...

    Abstract Unlabelled: The graft versus host disease after liver transplant is rare, with an incidence less than 1%, but with a high mortality (75-85%), especially due to infectious complications. It usually affects gastrointestinal tract, skin and blood system in the context of a normal liver graft function. There is no consensus on the most appropriate treatment: some articles support a reduction or even elimination of immunosuppressive drugs, while others published success with a dose increase.
    Clinical case: We report a case of a 68 year-old liver transplant recipient with a graft retrieved from an ABO identical cadaveric donor. After an uneventful postoperative period, he was readmitted presenting these symptoms: skin lesions, diarrhea and kidney failure. After ruling out infectious causes or drug toxicity, skin, duodenum and colon biopsies demonstrated characteristic histological changes of graft versus host disease grade III. Initially, supportive treatment along with methylprednisolone bolus were administered with good response. However, as the doses of corticosteroids decreased, the patient worsened again, requiring basiliximab. In spite of that, the patient progressively worsened with hematological involvement and, finally, an alteration of liver function tests prior to decease. The autopsy showed CMV and Herpes virus superinfection.
    Discussion: We report a new case of graft-versus-host disease after liver transplantation with fatal evolution due to viral superinfection despite the employed measures.
    MeSH term(s) Aged ; Antibodies, Monoclonal/therapeutic use ; Cytomegalovirus Infections/complications ; Fatal Outcome ; Graft vs Host Disease/drug therapy ; Graft vs Host Disease/etiology ; Humans ; Immunosuppressive Agents/therapeutic use ; Liver Transplantation/adverse effects ; Male ; Recombinant Fusion Proteins/therapeutic use ; Steroids/therapeutic use
    Chemical Substances Antibodies, Monoclonal ; Immunosuppressive Agents ; Recombinant Fusion Proteins ; Steroids ; basiliximab (9927MT646M)
    Language English
    Publishing date 2016-01
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 199: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Duodenal involvement by seminomatous tumors.

    Rodriguez-Lopez, Mario / Velasco-López, Rosalía / Mambrilla-Herrero, Sara / Bailon-Cuadrado, Martin / Plua, Katherine T / Diez-González, Luis M / Blanco-Álvarez, Jose I / Asensio-Díaz, Enrique / Gonzalo-Martín, Marta / Pérez-Saborido, Baltasar / Marcos-Rodríguez, Jose L

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2015  Volume 107, Issue 10, Page(s) 640–641

    Abstract: Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The ... ...

    Abstract Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread. Particularly, infiltration of duodenum is also rare, though its real frequency is not well defined. Moreover, the affinity for GI tract differs among the histological types of GCT, being seminomatous tumors an exceedingly unfrequent cause of duodenal infiltration. We herein present a recent case in our institution of severe anemia due to gastrointestinal bleeding in the context of giant retroperitoneal bulky metastatic mass infiltrating duodenum as first manifestation of a testicular pure seminoma.
    MeSH term(s) Adult ; Duodenal Neoplasms/diagnostic imaging ; Duodenal Neoplasms/pathology ; Duodenal Neoplasms/secondary ; Gastrointestinal Hemorrhage/etiology ; Gastroscopy ; Humans ; Male ; Neoplasms, Germ Cell and Embryonal/diagnostic imaging ; Neoplasms, Germ Cell and Embryonal/pathology ; Neoplasms, Germ Cell and Embryonal/surgery ; Seminoma/diagnostic imaging ; Seminoma/pathology ; Seminoma/secondary ; Testicular Neoplasms/diagnostic imaging ; Testicular Neoplasms/pathology ; Testicular Neoplasms/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2015-10
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2015.3646/2014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 199: Show issues Location:
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