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  1. Article ; Online: A comprehensive investigation of the medicinal efficacy of antimicrobial fusion peptides expressed in probiotic bacteria for the treatment of pan drug-resistant (PDR) infections.

    Safarpour-Dehkordi, Maryam / Chabok, Omid / Asgari, Mohsen / Khademi, Reyhaneh / Doosti, Abbas

    Archives of microbiology

    2024  Volume 206, Issue 3, Page(s) 93

    Abstract: The present work aimed to examine the intracellular antibacterial efficacy of Recombinant Lactobacillus acidophilus/antimicrobial peptides (AMPs) Melittin and Alyteserin-1a, specifically targeting Gram-negative bacteria. The first assessment was to ... ...

    Abstract The present work aimed to examine the intracellular antibacterial efficacy of Recombinant Lactobacillus acidophilus/antimicrobial peptides (AMPs) Melittin and Alyteserin-1a, specifically targeting Gram-negative bacteria. The first assessment was to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Recombinant L. acidophilus/AMPs versus Gram-negative and Gram-positive bacteria. In addition, the researchers examined the in vitro viability and safety of AMPs generated by L. acidophilus. The experiments included exposing the AMPs to elevated temperatures, proteases, cationic salts at physiological levels, and specific pH settings. The safety aspect was evaluated using hemolytic analysis utilizing sheep erythrocytes; cytotoxicity assays employing cell lines, and experiments on beneficial gut lactobacilli. An experiment was done using a time-kill method to assess the intracellular antibacterial efficacy of Recombinant L. acidophilus/AMPs compared to pathogenic varieties in HEp-2 cells. Previous investigations have shown that the MBC levels of recombinant L. acidophilus/AMPs were consistently two to four times higher than the equivalent MIC values when evaluated versus Gram-negative bacteria. Furthermore, the stability of the Recombinant L. acidophilus/AMPs showed variability when exposed to elevated temperatures (70 and 90 ℃), treated with protease enzymes (proteinase K, lysozyme), exposed to higher concentrations of physiological salts (150 mM NaCl and 2 mM MgCl
    MeSH term(s) Animals ; Sheep ; Melitten/pharmacology ; Salts ; Bacteria ; Anti-Infective Agents ; Anti-Bacterial Agents/pharmacology ; Lactobacillus ; Peptide Hydrolases ; Antimicrobial Peptides
    Chemical Substances Melitten (20449-79-0) ; Salts ; Anti-Infective Agents ; Anti-Bacterial Agents ; Peptide Hydrolases (EC 3.4.-) ; Antimicrobial Peptides
    Language English
    Publishing date 2024-02-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124824-8
    ISSN 1432-072X ; 0302-8933
    ISSN (online) 1432-072X
    ISSN 0302-8933
    DOI 10.1007/s00203-023-03823-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 805: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Book ; Online: Profitable Strategy Design for Trades on Cryptocurrency Markets with Machine Learning Techniques

    Asgari, Mohsen / Khasteh, Hossein

    2021  

    Abstract: AI and data driven solutions have been applied to different fields and achieved outperforming and promising results. In this research work we apply k-Nearest Neighbours, eXtreme Gradient Boosting and Random Forest classifiers for detecting the trend ... ...

    Abstract AI and data driven solutions have been applied to different fields and achieved outperforming and promising results. In this research work we apply k-Nearest Neighbours, eXtreme Gradient Boosting and Random Forest classifiers for detecting the trend problem of three cryptocurrency markets. We use these classifiers to design a strategy to trade in those markets. Our input data in the experiments include price data with and without technical indicators in separate tests to see the effect of using them. Our test results on unseen data are very promising and show a great potential for this approach in helping investors with an expert system to exploit the market and gain profit. Our highest profit factor for an unseen 66 day span is 1.60. We also discuss limitations of these approaches and their potential impact on Efficient Market Hypothesis.

    Comment: Manuscript Text Revised, Some Results Added
    Keywords Quantitative Finance - Trading and Market Microstructure ; Computer Science - Artificial Intelligence
    Subject code 006
    Publishing date 2021-05-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Morphological and molecular characterisation of Longidorus sabalanicus n. sp. (Nematoda: Longidoridae) from Iran

    Asgari, Mohsen / Eskandari, Ali / Castillo, Pablo / Palomares-Rius, Juan E.

    European journal of plant pathology. 2022 May, v. 163, no. 1

    2022  

    Abstract: Longidorus sabalanicus n. sp. is described and illustrated based on morphological, morphometric and molecular studies of two populations from north-western Iran. It was recovered from the rhizosphere of meadow grasses in East Azarbaijan province and the ... ...

    Abstract Longidorus sabalanicus n. sp. is described and illustrated based on morphological, morphometric and molecular studies of two populations from north-western Iran. It was recovered from the rhizosphere of meadow grasses in East Azarbaijan province and the rhizosphere of Astragalus sp. in Zanjan province. The new species is characterised by having a medium sized body, 3.8–5.1 mm in females and 3.6–4.7 in males; lip region anteriorly flattened, laterally rounded, set off from body contour by a slight depression; amphidial fovea pocket-shaped, without basal lobes; guiding ring at 25–30 μm from anterior end; odontostyle moderately long, 73.0–85.5 μm and odontophore weakly developed, 50.0–67.4 μm long; female reproductive system containing sperm, vulva located at 50–54% of body length; tail bluntly conoid, 41.0–55.0 μm long; males common in both populations, with 54.0–68.5 μm long spicules and seven to ten ventromedian precloacal supplements anterior to the adanal pair; and four juvenile developmental stages present. The alpha-numeric codes for identifying the new species are: A23-B2-C2-D3-E1-F2-G1-H12-I2-J1-K7. Morphologically, the new species most closely resembles to L. moniloides, L. rotundicaudatus, L. tabrizicus, L. artemisiae, L. asiaticus, L. behshahrensis, and L. elongatus. Morphological and morphometric differences of Longidorus sabalanicus n. sp. and the aforementioned species are discussed. In addition to morphological and morphometric data, molecular comparison analyses based on partial 18S rRNA, D2-D3 expansion segments of 28S rRNA and ITS1 region sequences, indicate that L. sabalanicus n. sp. is separated from other species and it is related phylogenetically with L. behshahrensis.
    Keywords Astragalus ; body length ; juveniles ; meadows ; morphometry ; new species ; phylogeny ; plant pathology ; rhizosphere ; spermatozoa ; tail ; vulva ; Iran
    Language English
    Dates of publication 2022-05
    Size p. 19-34.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 1196520-4
    ISSN 0929-1873
    ISSN 0929-1873
    DOI 10.1007/s10658-021-02454-x
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 1151: Show issues

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  4. Article ; Online: Safety climate assessment: a survey in an electric power distribution company.

    Kiani, Moien / Asgari, Mohsen / Abbas Gohari, Faezeh / Rezvani, Zahra

    International journal of occupational safety and ergonomics : JOSE

    2021  Volume 28, Issue 2, Page(s) 709–715

    Abstract: Introduction. ...

    Abstract Introduction.
    MeSH term(s) Cross-Sectional Studies ; Humans ; Organizational Culture ; Safety Management ; Surveys and Questionnaires
    Language English
    Publishing date 2021-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1335568-5
    ISSN 2376-9130 ; 1080-3548
    ISSN (online) 2376-9130
    ISSN 1080-3548
    DOI 10.1080/10803548.2020.1870832
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4764: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article ; Online: Co-expression network analysis for the identification of potential prostate cancer genes and in vitro confirmation of their expression in cell model in the presence of Staphylococcal

    Safarpour-Dehkordi, Maryam / Samimi-Dehkordi, Nooshin / Asgari, Mohsen / Khademi, Reihaneh / Kabirian-Dehkordi, Maryam / Amiri, Maryam / Aali, Faranak

    Nucleosides, nucleotides & nucleic acids

    2023  Volume 43, Issue 3, Page(s) 214–229

    Abstract: Prostate cancer has arisen as an important life-threatening malignancy in males worldwide. Therefore, it is important to study underlying molecular pathways to be able to proposed appropriate a novel pathway of apoptosis in prostate cancer. This study ... ...

    Abstract Prostate cancer has arisen as an important life-threatening malignancy in males worldwide. Therefore, it is important to study underlying molecular pathways to be able to proposed appropriate a novel pathway of apoptosis in prostate cancer. This study aimed to explore the molecular effects of Staphylococcal tsst-1 gene on PC3 cell line apoptosis by in silico and
    MeSH term(s) Male ; Humans ; Cell Line, Tumor ; Prostatic Neoplasms/genetics ; Apoptosis/genetics ; Transfection ; Cell Proliferation
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2008956-9
    ISSN 1532-2335 ; 1525-7770
    ISSN (online) 1532-2335
    ISSN 1525-7770
    DOI 10.1080/15257770.2023.2249544
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3870: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  6. Article: An Experimental Study of the Effects of Combined Exposure to Microwave and Heat on Gene Expression and Sperm Parameters in Mice.

    Gohari, Faezeh A / Saranjam, Behzad / Asgari, Mohsen / Omidi, Leila / Ekrami, Hamid / Moussavi-Najarkola, Seyyed Ali

    Journal of human reproductive sciences

    2014  Volume 10, Issue 2, Page(s) 128–134

    Abstract: Objectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group.: Aims: The objectives of this research were to determine the effects of separate and combined exposure ... ...

    Abstract Objectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group.
    Aims: The objectives of this research were to determine the effects of separate and combined exposure to 900-MHz MW (as representative of cell phone radiation) and heat on gene expression and spermogram of male mice.
    Settings and design: This experimental animal study was conducted in the school of public health.
    Materials and methods: The study was done on 12 male mice randomly divided into four groups (21-23 g): control, test group 1 with separate exposure to 900-MHz MW, test group 2 with separate exposure to hot and sultry climate, and test group 3 with simultaneous whole body exposures to 900-MHz MW and hot and sultry climate. In all studied groups, gene expression and sperm parameters were measured.
    Results: Tissue samples in all test groups showed integrity of the seminiferous tubule followed by all types of germ line cells. Significant increases in the number of dead sperms in mice with separate exposure to heat were observed in comparison with the other studied groups (
    Conclusion: Separate and combined exposure to 900-MHz MW and heat may induce adverse effects on sperm parameters and gene expression of studied male mice.
    Language English
    Publishing date 2014-12-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 2418984-4
    ISSN 1998-4766 ; 0974-1208
    ISSN (online) 1998-4766
    ISSN 0974-1208
    DOI 10.4103/jhrs.JHRS_136_16
    Database MEDical Literature Analysis and Retrieval System OnLINE

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