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  1. Article: 3D Printing/Additive Manufacturing of Single- Implant Overdentures. A Randomized controlled clinical trial.

    Ibrahim, Wafaa Ibrahim / Ashraf, Ahmed / ElAwady, Dina

    International journal of computerized dentistry

    2024  

    Abstract: Objectives: Mandibular single-implant overdenture is a well-established treatment modality for the management of completely edentulous patients. The use of CAD/CAM printing technology to fabricate complete dentures and overdentures is burgeoning. The ... ...

    Abstract Objectives: Mandibular single-implant overdenture is a well-established treatment modality for the management of completely edentulous patients. The use of CAD/CAM printing technology to fabricate complete dentures and overdentures is burgeoning. The trial aimed to clinically evaluate 3D-printed single-implant overdentures and compare outcomes to those of overdentures manufactured using conventional techniques.
    Materials and methods: A randomized clinical trial (RCT) was designed. Twenty-eight participants were randomly allocated into two equal groups. Participants in the control group received conventionally manufactured single-implant overdentures, while participants in the printed group received digital light processing (DLP) printed single-implant overdentures. An evaluation was conducted to assess the rates of implant survival and success, as well as overdenture survival and success, along with the measurement of maximum biting force (MBF) over a one-year follow-up period. Data was collected and subjected to statistical analysis. Statistical significance was determined using a two-sided p-value with a threshold of less than 0.05.
    Results: The printed denture group had higher implant survival (100%) and success rates (92.8%) compared to the conventional denture group (85.7% survival, 85.7% success). Overdenture survival and success rates were 100% in the printed group and 78.6% in the conventional group. Both groups showed a significant increase in maximum biting force (MBF) at 3, 6, and 12 months of follow-up (P<0.001). The printed group demonstrated a statistically significant improvement in MBF compared to the conventional group (P<0.001).
    Conclusions: 3D-printed mandibular single-implant overdentures may represent an alternative to conventionally fabricated ones.
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1463532-x
    ISSN 1463-4201
    ISSN 1463-4201
    DOI 10.3290/j.ijcd.b4870843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Applications of Different Classification Machine Learning Techniques to Predict Formation Tops and Lithology While Drilling

    Ahmed Farid Ibrahim / Ashraf Ahmed / Salaheldin Elkatatny

    ACS Omega, Vol 8, Iss 45, Pp 42152-

    2023  Volume 42163

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Experimental Investigation of Using Manganese Monoxide as a Hydrogen Sulfide Scavenger for Aqueous Drilling Fluids

    Ashraf Ahmed / Salaheldin Elkatatny / Sagheer A. Onaizi

    ACS Omega, Vol 8, Iss 49, Pp 46738-

    2023  Volume 46745

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Histopathological effects of the fruit extract of Citrullus colocynthis on the ovary of the tick Hyalomma dromedarii.

    Ali, Asmaa Ali Baioumy / Montasser, Ashraf Ahmed / Mohamed, Salma Nabil Ahmed

    Experimental & applied acarology

    2024  Volume 92, Issue 2, Page(s) 275–295

    Abstract: Hyalomma dromedarii is the predominant tick species parasitizing camels in Egypt which leads to mortalities in young animals that result in economic losses. It can transmit a lot of pathogens to animals and humans, such as the Crimean-Congo hemorrhagic ... ...

    Abstract Hyalomma dromedarii is the predominant tick species parasitizing camels in Egypt which leads to mortalities in young animals that result in economic losses. It can transmit a lot of pathogens to animals and humans, such as the Crimean-Congo hemorrhagic fever virus, the Dhori virus, Kadam virus, Theileria annulata and spotted fever rickettsia. The continuous use of chemical acaricides has negative impact on the environment and almost led to acaricidal resistance, and hence the plant extracts represent alternative methods for controlling ticks. The present study was carried out to assess the histopathological effects on the ovary of fed female Hyalomma dromedarii following immersion in the ethanolic extract of fruits of Citrullus colocynthis (100 mg/mL). Light, scanning and transmission electron microscopy observations provided evidence that Citrullus colocynthis caused extensive damage to oocytes. Destruction of the internal organelles of oocytes, along with delay and/or inhibition of vitellogenesis were demonstrated. This is the first histological study that points to damage in H. dromedarii ovaries following treatment with the ethanolic extract of fruits of C. colocynthis. The data presented suggest that the plant extract affects the ovary either directly by entering the oocytes and/or indirectly by damaging the gut cells and digestion of blood that interfere with the development of oocytes, so it can be used as a promising agent for tick control.
    MeSH term(s) Humans ; Female ; Animals ; Ticks ; Ovary ; Citrullus colocynthis ; Fruit ; Ixodidae/physiology
    Language English
    Publishing date 2024-02-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 11320-7
    ISSN 1572-9702 ; 0168-8162
    ISSN (online) 1572-9702
    ISSN 0168-8162
    DOI 10.1007/s10493-023-00895-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cholesterol Granuloma

    Sara Hassen / Gawahir Ali / Ashraf Ahmed / Wael Goravey

    European Journal of Case Reports in Internal Medicine (2022)

    An Underrecognized Cause of Benign Lung Granuloma

    2022  

    Abstract: A cholesterol granuloma is a benign lesion that can occur in various organs, mimicking other pathologies. We present the case of a 35-year-old man presenting with asymptomatic lung and pleural lesions which were suspected to be pulmonary tuberculosis but ...

    Abstract A cholesterol granuloma is a benign lesion that can occur in various organs, mimicking other pathologies. We present the case of a 35-year-old man presenting with asymptomatic lung and pleural lesions which were suspected to be pulmonary tuberculosis but found to be cholesterol granuloma on biopsy. Cholesterol granulomas are a rare mimic of common lung pathology and should be considered in the differential diagnosis if the initial investigations are not informative.
    Keywords pulmonary tuberculosis ; invasive aspergillosis ; type ii diabetes ; immunocompromised ; Medicine ; R
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Improvement of Hydrogen Sulfide Scavenging via the Addition of Monoethanolamine to Water-Based Drilling Fluids

    Ashraf Ahmed / Sagheer A. Onaizi / Salaheldin Elkatatny

    ACS Omega, Vol 7, Iss 32, Pp 28361-

    2022  Volume 28368

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Outcomes of one-stage feminizing genitoplasty in children with congenital adrenal hyperplasia and severe virilization.

    Abosena, Wael / Almetaher, Hisham AlMohamady / El Attar, Ashraf Ahmed / Nofal, Ahmed Hassan / Elhalaby, Essam Abdelaziz

    Pediatric surgery international

    2024  Volume 40, Issue 1, Page(s) 72

    Abstract: Purpose: To present our surgical experience and outcomes in congenital adrenal hyperplasia (CAH) patients with severe virilization using a combined technique of total urogenital mobilization (TUM) and a modified pull-through vaginoplasty to perform a ... ...

    Abstract Purpose: To present our surgical experience and outcomes in congenital adrenal hyperplasia (CAH) patients with severe virilization using a combined technique of total urogenital mobilization (TUM) and a modified pull-through vaginoplasty to perform a safe and effective one-stage feminizing genital reconstruction for these children.
    Methods: Fourteen CAH patients with severe virilization, defined by a Prader IV and V rating of the external genitalia, underwent TUM followed by a limited vaginal pull-through procedure from June 2016 to December 2020. Postoperative anatomical and cosmetic outcomes, and urinary continence, were evaluated.
    Results: Out of the 14 cases in this study, 8 were classified as prader IV and 6 as Prader V. The median age at surgery was 11 months (range 6-36 months), and the mean urethral length was 1.4 cm (range 1.2-1.8 cm). The median follow-up period was 4 years. Our cosmetic outcomes were good in 11 (78.5%), satisfactory in 2, and poor in one case. All patients achieved age-appropriate toilet training without urinary incontinence.
    Conclusion: Adopting our surgical approach of TUM with modified pull-through vaginoplasty has simplified feminizing surgical reconstruction in CAH cases with severe genital atypia and a very high vaginal confluence with short urethral length, yielding adequate introitus with good anatomical and cosmetic appearance and adequate urinary continence outcomes.
    MeSH term(s) Child ; Female ; Humans ; Infant ; Child, Preschool ; Adrenal Hyperplasia, Congenital/complications ; Adrenal Hyperplasia, Congenital/surgery ; Virilism ; Postoperative Period ; Urethra ; Vagina/surgery
    Language English
    Publishing date 2024-03-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-024-05638-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Management of clinical infections of

    Kadry, Ashraf Ahmed / El-Antrawy, May Ayman / El-Ganiny, Amira Mohammed

    Iranian journal of microbiology

    2023  Volume 14, Issue 4, Page(s) 466–474

    Abstract: Background and objectives: Escherichia coli (E. coli): Materials and methods: 140 clinical isolates of : Results: The percentage of ESBL production among the tested isolates was 46.4%. Isolates were highly resistant to classical β-lactam/β- ... ...

    Abstract Background and objectives: Escherichia coli (E. coli)
    Materials and methods: 140 clinical isolates of
    Results: The percentage of ESBL production among the tested isolates was 46.4%. Isolates were highly resistant to classical β-lactam/β-lactamase inhibitor combinations, where (40.7%) and (42.9%) of isolates were resistant to amoxicillin/clavulanate and ampicillin/sulbactam, respectively. While new β-lactam/β-lactamase inhibitor combinations had promising inhibitory action. The addition of novel β-lactamase inhibitors restored the susceptibility of isolates, where (94.3%) of isolates became susceptible to ceftazidime/avibactam combination, followed by cefoperazone/sulbactam (89.2%) and cefepime/enmetazobactam (85.7%). The synergistic effect seems to be effective where ceftazidime and avibactam were synergistic in 80% of isolates.
    Conclusion: The antibacterial activity of some antimicrobial agents can be enhanced by the addition of new β-lactamase inhibitors. Further
    Language English
    Publishing date 2023-01-18
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2652849-6
    ISSN 2008-4447 ; 2008-3289
    ISSN (online) 2008-4447
    ISSN 2008-3289
    DOI 10.18502/ijm.v14i4.10232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Identification of Potential Inhibitors of 3CL Protease of SARS-CoV-2 From ZINC Database by Molecular Docking-Based Virtual Screening.

    Abdusalam, Ashraf Ahmed Ali / Murugaiyah, Vikneswaran

    Frontiers in molecular biosciences

    2020  Volume 7, Page(s) 603037

    Abstract: The rapid outbreak of Coronavirus Disease 2019 (COVID-19) that was first identified in Wuhan, China is caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The 3CL protease (3CLpro) is the main protease of the SARS-CoV-2, which ...

    Abstract The rapid outbreak of Coronavirus Disease 2019 (COVID-19) that was first identified in Wuhan, China is caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The 3CL protease (3CLpro) is the main protease of the SARS-CoV-2, which is responsible for the viral replication and therefore considered as an attractive drug target since to date there is no specific and effective vaccine available against this virus. In this paper, we reported molecular docking-based virtual screening (VS) of 2000 compounds obtained from the ZINC database and 10 FDA-approved (antiviral and anti-malaria) on 3CLpro using AutoDock Vina to find potential inhibitors. The screening results showed that the top four compounds, namely ZINC32960814, ZINC12006217, ZINC03231196, and ZINC33173588 exhibited high affinity at the 3CLpro binding pocket. Their free energy of binding (FEB) were -12.3, -11.9, -11.7, and -11.2 kcal/mol while AutoDock Vina scores were -12.61, -12.32, -12.01, and -11.92 kcal/mol, respectively. These results were better than the co-crystallized ligand N3, whereby its FEB was -7.5 kcal/mol and FDA-approved drugs. Different but stable interactions were obtained between the four identified compounds with the catalytic dyad residues of the 3CLpro. In conclusion, novel 3CLpro inhibitors from the ZINC database were successfully identified using VS and molecular docking approach, fulfilling the Lipinski rule of five, and having low FEB and functional molecular interactions with the target protein. The findings suggests that the identified compounds may serve as potential leads that act as COVID-19 3CLpro inhibitors, worthy for further evaluation and development.
    Language English
    Publishing date 2020-12-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2020.603037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gemfibrozil-Induced Polyuria

    Ashraf Ahmed / Edmond Okotcha / Abdul-Hussein Saad

    European Journal of Case Reports in Internal Medicine (2021)

    2021  

    Abstract: Gemfibrozil is a lipid-regulating agent used mainly to treat patients with hypertriglyceridaemia, especially those at risk for acute pancreatitis. Like any other pharmacological agent, gemfibrozil has known adverse effects, mainly gastrointestinal, such ... ...

    Abstract Gemfibrozil is a lipid-regulating agent used mainly to treat patients with hypertriglyceridaemia, especially those at risk for acute pancreatitis. Like any other pharmacological agent, gemfibrozil has known adverse effects, mainly gastrointestinal, such as cholelithiasis, gallstones, elevated transaminase, and other non-specific symptoms including dyspepsia, nausea and vomiting. Other reported adverse reactions are dizziness and vertigo, myopathy and rhabdomyolysis, angioedema, urticaria and rash. As far as we knew, gemfibrozil does not have urinary tract adverse reactions. In this report, we present a case of polyuria secondary to gemfibrozil with a score of 9 on the Naranjo scale, and a literature review.
    Keywords gemfibrozil ; anti-hyperlipidaemic ; urinary side effects ; polyuria ; Medicine ; R
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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