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  1. Book ; Online ; E-Book: Current thoughts on dementia

    Ashraf, Ghulam Md / Sahab Uddin, Md

    from risk factors to therapeutic interventions

    2022  

    Author's details Ghulam Md Ashraf, Md. Sahab Uddin, editors
    Keywords Dementia/Treatment ; Diseases/Risk factors ; Demència ; Terapèutica
    Subject code 616.83
    Language English
    Size 1 online resource (621 pages)
    Publisher Springer
    Publishing place Gateway East, Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-7606-2 ; 9789811676055 ; 978-981-16-7606-2 ; 9811676054
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Advances in Dementia Research

    Ashraf, Ghulam Md

    2019  

    Keywords Physiological & neuro-psychology, biopsychology ; biomarkers, alzheimer's disease, neurodegeneration, metabolic syndrome, memory, enzymes
    Language English
    Size 1 electronic resource (64 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030645901
    ISBN 9781839621284 ; 1839621281
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Biological, diagnostic and therapeutic advances in Alzheimer's disease

    Ashraf, Ghulam Md / Alexiou, Athanasios

    non-pharmacological therapies for Alzheimer's disease

    2019  

    Author's details Ghulam Md Ashraf, Athanasios Alexiou editors
    Keywords Neurosciences ; Neurobiology ; Rehabilitation medicine ; Human genetics
    Subject code 612.8
    Language English
    Size 1 Online-Ressource (xi, 293 Seiten), Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020329234
    ISBN 978-981-13-9636-6 ; 9789811396359 ; 981-13-9636-1 ; 9811396353
    DOI 10.1007/978-981-13-9636-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online ; E-Book: Quality control of cellular protein in neurodegenerative disorders

    Uddin, Sahab / Ashraf, Ghulam Md

    2020  

    Author's details Md. Sahab Uddin, Ghulam Md. Ashraf
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xx, 515 Seiten), Illustrationen
    Publisher IGI Global
    Publishing place Hershey
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020437997
    ISBN 978-1-79981-318-7 ; 9781799813170 ; 1-79981-318-5 ; 1799813177
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Mitochondrial Medicine for Neurological Disorders.

    Sahab Uddin, Md / Alghamdi, Badrah S / Ashraf, Ghulam Md

    Current neuropharmacology

    2023  Volume 21, Issue 5, Page(s) 1024–1025

    MeSH term(s) Humans ; Mitochondria/genetics ; Nervous System Diseases/therapy ; Mitochondrial Diseases/therapy ; DNA, Mitochondrial
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2023-05-18
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X2105230320095644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: New Emerging Trends in Protein and Peptide Based Therapeutic Approaches - Part I.

    Ashraf, Ghulam Md

    Current protein & peptide science

    2018  Volume 19, Issue 9, Page(s) 840

    MeSH term(s) Humans ; Peptides/therapeutic use ; Proteins/therapeutic use
    Chemical Substances Peptides ; Proteins
    Language English
    Publishing date 2018-08-23
    Publishing country United Arab Emirates
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2045662-1
    ISSN 1875-5550 ; 1389-2037
    ISSN (online) 1875-5550
    ISSN 1389-2037
    DOI 10.2174/138920371909180717093011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: New Emerging Trends in Protein and Peptide Based Therapeutic Approaches - Part II.

    Ashraf, Ghulam Md

    Current protein & peptide science

    2018  Volume 19, Issue 10, Page(s) 936

    MeSH term(s) Humans ; Peptides/therapeutic use ; Proteins/therapeutic use
    Chemical Substances Peptides ; Proteins
    Language English
    Publishing date 2018-08-13
    Publishing country United Arab Emirates
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2045662-1
    ISSN 1875-5550 ; 1389-2037
    ISSN (online) 1875-5550
    ISSN 1389-2037
    DOI 10.2174/138920371910180719094236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Dysregulation of Neuronal Iron in Alzheimer's Disease.

    Uddin, Md Sahab / Ashraf, Ghulam Md

    Current neuropharmacology

    2021  Volume 21, Issue 11, Page(s) 2247–2250

    MeSH term(s) Humans ; Alzheimer Disease ; Iron ; Neurons
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2021-12-30
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X20666211231163544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Gene Therapy for Neuroprotection and Neurorestoration-Part III.

    Ashraf, Ghulam Md / Uddin, Md Sahab

    Current gene therapy

    2021  Volume 21, Issue 1, Page(s) 2

    MeSH term(s) Genetic Therapy ; Humans ; Nervous System Diseases/genetics ; Nervous System Diseases/therapy ; Neuroprotection
    Language English
    Publishing date 2021-02-13
    Publishing country United Arab Emirates
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2146187-9
    ISSN 1875-5631 ; 1566-5232
    ISSN (online) 1875-5631
    ISSN 1566-5232
    DOI 10.2174/156652322101210209103113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comprehensive Perspective Towards the Management of Proteinopathies by Elucidating Protein Misfolding and Aggregation.

    Ahanger, Ishfaq Ahmad / Ashraf, Ghulam Md / Sharma, Anurag / Islam, Asimul

    CNS & neurological disorders drug targets

    2023  Volume 23, Issue 2, Page(s) 153–180

    Abstract: Protein misfolding and aggregation is the phenomenon of the generic propensity of proteins, considered as a dark side of the protein world, and its exact mechanism is still not deciphered. Understanding the complexity of protein aggregation is currently ... ...

    Abstract Protein misfolding and aggregation is the phenomenon of the generic propensity of proteins, considered as a dark side of the protein world, and its exact mechanism is still not deciphered. Understanding the complexity of protein aggregation is currently the primary apprehension and challenge in biology and medicine due to their association with various debilitating human proteinopathies and neurodegenerative diseases. The mechanism of protein aggregation, associated diseases, and the development of efficient therapeutic strategies against these diseases are very challenging. These diseases are caused by different proteins, each protein with different mechanisms and consisting of various microscopic phases or events. These microscopic steps are functioning on different timescales during aggregation. Here, we highlighted the different features and current trends in protein aggregation. The study thoroughly recapitulates the various factors influencing, possible causes, types of aggregates and aggregation, their different proposed mechanisms, and the methods used to study the aggregation. Additionally, the formation and elimination of misfolded or aggregated proteins in the cell, the role of the ruggedness of the protein folding landscape in protein aggregation, proteinopathies, and the challenges for their prevention are comprehensively elucidated. A holistic understanding of different aspects of aggregation, molecular steps governing the various features of protein quality control, and crucial queries about the modulation of these processes and their interactions with other systems in cellular protein quality control can be considered conducive to comprehending the mechanism, designing effective approaches towards prevention of protein aggregation, rationalizing the etiology and development of novel strategies against therapy and management of the proteinopathies.
    Language English
    Publishing date 2023-03-05
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2228394-8
    ISSN 1996-3181 ; 1871-5273
    ISSN (online) 1996-3181
    ISSN 1871-5273
    DOI 10.2174/1871527322666230306085937
    Database MEDical Literature Analysis and Retrieval System OnLINE

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