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  1. Article ; Online: Renewing the fight: A call to action for diabetes and chronic kidney disease.

    Pecoits-Filho, Roberto / Jimenez, Beatriz Yanez / Ashuntantang, Gloria E / de Giorgi, Federica / De Cosmo, Salvatore / Groop, Per-Henrik / Liew, Adrien / Hradsky, Anne / Pontremoli, Roberto / Sola, Laura / Ceriello, Antonio

    Diabetes research and clinical practice

    2023  Volume 203, Page(s) 110902

    Title translation A policy brief by the International Diabetes Federation and the International Society of Nephrology.
    Language German
    Publishing date 2023-09-07
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632523-3
    ISSN 1872-8227 ; 0168-8227
    ISSN (online) 1872-8227
    ISSN 0168-8227
    DOI 10.1016/j.diabres.2023.110902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Kidneys and women's health: key challenges and considerations.

    Ashuntantang, Gloria E / Garovic, Vesna D / Heilberg, Ita P / Lightstone, Liz

    Nature reviews. Nephrology

    2018  Volume 14, Issue 3, Page(s) 203–210

    Abstract: The theme of World Kidney Day 2018 is 'kidneys and women's health: include, value, empower'. To mark this event, Nature Reviews Nephrology asked four leading researchers to discuss key considerations related to women's kidney health, including specific ... ...

    Abstract The theme of World Kidney Day 2018 is 'kidneys and women's health: include, value, empower'. To mark this event, Nature Reviews Nephrology asked four leading researchers to discuss key considerations related to women's kidney health, including specific risk factors, as well as the main challenges and barriers to care for women with kidney disease and how these might be overcome. They also discuss policies and systems that could be implemented to improve the kidney health of women and their offspring and the areas of research that are needed to improve the outcomes of kidney disease in women.
    MeSH term(s) Female ; Health Policy ; Health Services Accessibility ; Humans ; Kidney Diseases/epidemiology ; Kidney Diseases/prevention & control ; Prevalence ; Risk Factors ; Women's Health
    Language English
    Publishing date 2018-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/nrneph.2017.188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Adult T-type lymphoblastic lymphoma presenting as hypercalcemic crisis and aplastic anemia: a case report.

    Essouma, Mickael / Soh, Dorothée M / Temgoua, Mazou N / Gobina, Ronald M / Nono, Aristide T / Atenguena, Etienne Olivier / Maimouna, Mahamat / Ashuntantang, Gloria E

    Journal of medical case reports

    2019  Volume 13, Issue 1, Page(s) 305

    Abstract: Background: Hypercalcemia and aplastic anemia are two uncommon presentations of non-Hodgkin lymphoma that potentially worsen the disease prognosis. Although hypercalcemia has been reported in the B-cell subtypes and some T-cell subtypes of non-Hodgkin ... ...

    Abstract Background: Hypercalcemia and aplastic anemia are two uncommon presentations of non-Hodgkin lymphoma that potentially worsen the disease prognosis. Although hypercalcemia has been reported in the B-cell subtypes and some T-cell subtypes of non-Hodgkin lymphoma, it has not been described in T-cell lymphoblastic lymphoma. The same applies to aplastic anemia, which is also not described in T-type lymphomas.
    Case presentation: We report a case of a 52-year-old Cameroonian man with acute kidney injury who presented with confusion, abdominal pain, constipation, polyuria, polydipsia, calciphylaxis, enlarged lymph nodes, tachycardia, and a blood pressure of 170/88 mmHg. Laboratory investigations revealed hypercalcemia (total/ionized 199.5/101.75 mg/L), normal serum phosphorus (40.20 mg/L), and a low intact parathyroid hormone (9.70 pg/ml). Complete blood count revealed pancytopenia. Peripheral blood smear confirmed thrombocytopenia but showed neither blasts nor flower cells. Bone marrow aspirate revealed hypocellularity with no blasts or fibrosis. Lymph node biopsy was suggestive of T-cell precursor lymphoma. T-lymphoblastic lymphoma presenting with hypercalcemic crisis and aplastic anemia was diagnosed, and the patient received the cyclophosphamide-doxorubicin-vincristine-prednisone protocol of chemotherapy together with filgrastim and whole-blood transfusion for aplastic anemia. The short-term outcome was fatal, however.
    Conclusions: Severe hypercalcemia and aplastic anemia are potential paraneoplastic syndromes of adult T-type lymphoblastic lymphoma, with fatal short-term outcome.
    MeSH term(s) Anemia, Aplastic/etiology ; Fatal Outcome ; Humans ; Hypercalcemia/etiology ; Male ; Middle Aged ; Paraneoplastic Syndromes/diagnosis ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis
    Language English
    Publishing date 2019-10-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-019-2225-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Current Status and Future of End-Stage Kidney Disease in Gulf Cooperation Council Countries: Challenges and Opportunities.

    Vachharajani, Tushar / Jasuja, Sanjiv / AlSahow, Ali / G Alghamdi, Saeed M / Al-Aradi, Ali H / Al Salmi, Issa / Bernieh, Bassam / Bahbahani, Yousif / Alali, Fadwa / Ramachandran, Raja / Alexander, Suceena / Mandal, Sandeep K / Malhotra, Rajeev K / Sahay, Manisha / Bhargava, Vinant / Jha, Vivekanand / Rana, Devendra Singh / Sagar, Gaurav / Bahl, Anupam /
    Kher, Vijay / Prasad, Narayan / Kumar, Krishnaswamy S / Alrukhaimi, Mona / Ashuntantang, Gloria E / Verma, Shalini / Gallieni, Maurizio

    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

    2022  Volume 32, Issue 4, Page(s) 1073–1088

    Abstract: There is a paucity of data on epidemiology along with an incomplete registry of end-stage kidney disease (ESKD), nephrologist workforce, and variability among the countries of Gulf Cooperation Council (GCC). The study is an observation, descriptive study ...

    Abstract There is a paucity of data on epidemiology along with an incomplete registry of end-stage kidney disease (ESKD), nephrologist workforce, and variability among the countries of Gulf Cooperation Council (GCC). The study is an observation, descriptive study which aimed to describe current ESKD burden, nephrologist density, and kidney care infrastructure in GCC. Responses to a questionnaire-based survey obtained from representatives of the Nephrology Societies of GCC countries were analyzed. The categorical variables were compared using Chi-square test. A P = 5% was considered as significant. The mean prevalence of ESKD per million populations (pmp) was 551, highest in Oman (1000/pmp), least in Qatar (347/pmp). Predominant etiology in GCC was diabetes mellitus (DM) and hypertension (HTN) (100%, each), followed by chronic glomerulonephritis (66.7%). A transplant registry was maintained by all GCC countries. Hemodialysis (HD) (67.2%) was the most opted modality of kidney replacement therapy (KRT), followed by kidney transplantation (22%) and peritoneal dialysis (9.6%); 1.0% of patients opted for conservative management. Unplanned initiation of HD was three times more common. The access distribution among incident and prevalent HD patients respectively was (i) nontunneled central catheter (nTCC) (58.7 ± 36.6 vs. 1.5 ± 1.5), (ii) tunneled central catheter (23.5 ± 29.9 vs. 33.6 ± 10.0), and (iii) arteriovenous fistula (17.3± 14.4 vs. 57.8 ± 11.86). Death and transplantation were the reasons for dropout from HD. GCC has adequate kidney care infrastructure. There are 1686 nephrologists [range: Bahrain 9, Kingdom of Saudi Arabia (KSA) 1279]. Qatar, KSA, and Kuwait provide training in kidney biopsy; all countries except Bahrain have formal training programs for nTCC placement. ESKD prevalence is high, DM, HTN; glome-rulonephritis (GN) is the most common causes. The need for KRT is expected to rise in GCC. HD is the predominant KRT modality with a high prevalence of dialysis catheters as vascular access.
    MeSH term(s) Data Collection ; Humans ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Kidney Transplantation ; Oman/epidemiology ; Registries ; Renal Dialysis ; Saudi Arabia
    Language English
    Publishing date 2022-03-01
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 1379955-1
    ISSN 1319-2442
    ISSN 1319-2442
    DOI 10.4103/1319-2442.338281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Complications of chronic kidney disease: current state, knowledge gaps, and strategy for action.

    Bello, Aminu K / Alrukhaimi, Mona / Ashuntantang, Gloria E / Basnet, Shakti / Rotter, Ricardo C / Douthat, Walter G / Kazancioglu, Rumeyza / Köttgen, Anna / Nangaku, Masaomi / Powe, Neil R / White, Sarah L / Wheeler, David C / Moe, Orson

    Kidney international supplements

    2017  Volume 7, Issue 2, Page(s) 122–129

    Abstract: The International Society of Nephrology has adopted a proactive approach to defining the current state of kidney care and unmet needs through a multifaceted Closing the Gaps initiative. As part of this initiative, the International Society of Nephrology ... ...

    Abstract The International Society of Nephrology has adopted a proactive approach to defining the current state of kidney care and unmet needs through a multifaceted Closing the Gaps initiative. As part of this initiative, the International Society of Nephrology convened a meeting of experts to develop an approach to tackle acute kidney injury and chronic kidney disease (CKD). This manuscript expands on the recently published International Society of Nephrology CKD Roadmap and reports on the discussions of the working group assigned to the task of reviewing the global impact of complication of CKD. The working group defined the following goals: Goal 1: Optimize the management of anemia and endocrine and metabolic abnormalities associated with CKD. The impact of these conditions at a global level is not well understood, particularly in regions where renal replacement therapy is not readily available. Some treatment regimens may be affordable in low- and middle-income countries and if implemented, could have an impact on the burden of suffering associated with CKD. Goal 2: Improve the prevention and management of cardiovascular complications linked to CKD. Most research on cardiovascular complications of CKD has focused on atherosclerotic diseases (myocardial infarction, ischemic stroke, and peripheral gangrene). There has been growing recognition that other forms of cardiovascular diseases, such as heart failure, valvular disease and arrhythmias, have a major impact on patient outcomes. Much less is known about the mechanisms and treatment of these non-atherosclerotic complications. Goal 3: Improve the diagnosis and management of symptoms associated with CKD. Symptom management is one of the greatest challenges in the management of CKD, with limited knowledge about the mechanisms associated with the development of these common problems and how best to characterize them into usable clinical phenotypes. Improved understanding of the complications of CKD may alleviate suffering and prolong life among millions of people worldwide both in developed countries and in regions where renal replacement therapy is not widely available.
    Language English
    Publishing date 2017-09-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 193442-9
    ISSN 2157-1716 ; 2157-1724 ; 0098-6577
    ISSN (online) 2157-1716
    ISSN 2157-1724 ; 0098-6577
    DOI 10.1016/j.kisu.2017.07.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: National health policies and strategies for addressing chronic kidney disease: Data from the International Society of Nephrology Global Kidney Health Atlas.

    Neuen, Brendon L / Bello, Aminu K / Levin, Adeera / Lunney, Meaghan / Osman, Mohamed A / Ye, Feng / Ashuntantang, Gloria E / Bellorin-Font, Ezequiel / Gharbi, Mohammed Benghanem / Davison, Sara / Ghnaimat, Mohammad / Harden, Paul / Jha, Vivekanand / Kalantar-Zadeh, Kamyar / Kerr, Peter G / Klarenbach, Scott / Kovesdy, Csaba P / Luyckx, Valerie / Ossareh, Shahrzad /
    Perl, Jeffrey / Rashid, Harun Ur / Rondeau, Eric / See, Emily J / Saad, Syed / Sola, Laura / Tchokhonelidze, Irma / Tesar, Vladimir / Tungsanga, Kriang / Kazancioglu, Rumeyza Turan / Wang, Angela Yee-Moon / Yang, Chih-Wei / Zemchenkov, Alexander / Zhao, Ming-Hui / Jager, Kitty J / Caskey, Fergus J / Perkovic, Vlado / Jindal, Kailash K / Okpechi, Ikechi G / Tonelli, Marcello / Feehally, John / Harris, David C / Johnson, David W

    PLOS global public health

    2023  Volume 3, Issue 2, Page(s) e0001467

    Abstract: National strategies for addressing chronic kidney disease (CKD) are crucial to improving kidney health. We sought to describe country-level variations in non-communicable disease (NCD) strategies and CKD-specific policies across different regions and ... ...

    Abstract National strategies for addressing chronic kidney disease (CKD) are crucial to improving kidney health. We sought to describe country-level variations in non-communicable disease (NCD) strategies and CKD-specific policies across different regions and income levels worldwide. The International Society of Nephrology Global Kidney Health Atlas (GKHA) was a multinational cross-sectional survey conducted between July and October 2018. Responses from key opinion leaders in each country regarding national NCD strategies, the presence and scope of CKD-specific policies, and government recognition of CKD as a health priority were described overall and according to region and income level. 160 countries participated in the GKHA survey, comprising 97.8% of the world's population. Seventy-four (47%) countries had an established national NCD strategy, and 53 (34%) countries reported the existence of CKD-specific policies, with substantial variation across regions and income levels. Where CKD-specific policies existed, non-dialysis CKD care was variably addressed. 79 (51%) countries identified government recognition of CKD as a health priority. Low- and low-middle income countries were less likely to have strategies and policies for addressing CKD and have governments which recognise it as a health priority. The existence of CKD-specific policies, and a national NCD strategy more broadly, varied substantially across different regions around the world but was overall suboptimal, with major discrepancies between the burden of CKD in many countries and governmental recognition of CKD as a health priority. Greater recognition of CKD within national health policy is critical to improving kidney healthcare globally.
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0001467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa

    Elsayed, Hesham M / Wadee, Shoyab / Zaki, Mohamad S / Were, Anthony JO / Ashuntantang, Gloria E / Bamgboye, Ebun L / Davids, Mogamat Razeen / Hafez, Mohamed H / Mahamat, Maimouna / Naicker, Saraladevi / Niang, Abdou / Seck, Sidy M / Swanepoel, Charles R / Tannor, Elliot K / Twahir, Ahmed / Yao, K Hubert

    African Journal of Nephrology; Vol 23, No; 109-126 ; 2518-4601 ; 2306-8205

    2020  Volume 1

    Abstract: Africa trails the rest of the world in COVID-19 cases and deaths. However, as the pandemic spreads through the continent, we expect increases in community infection in the months ahead. Patients with kidney infection, especially those with end-stage ... ...

    Abstract Africa trails the rest of the world in COVID-19 cases and deaths. However, as the pandemic spreads through the continent, we expect increases in community infection in the months ahead. Patients with kidney infection, especially those with end-stage kidney disease and those with kidney transplants, are at high risk for acquiring the disease and dying from it. While there is limited evidence for the benefit of interventions, we have the advantage of learning from the experiences of those in China, Europe and the Americas. This document sets forth guidance for dealing with our patients who have acute and chronic kidney disease, including those on renal replacement therapy and the staff involved in their care. Emphasis is placed on preparedness and prevention strategies. As evidence and experience accumulate, it is likely that updated guidance will be needed.L’Afrique suit le reste du monde en termes de nombre de cas et de décès dus à COVID-19. Cependant, alors que la pandémie se propage à travers le continent, nous prévoyons une augmentation de l’infection communautaire dans les mois à venir. Les patients atteints d’une maladie rénale, en particulier ceux atteints d’une maladie rénale chronique en phase terminale et ceux ayant subi une transplantation rénale, courent un risque élevé de contracter la maladie et d’en mourir. Bien que les preuves d’interventions soient limitées, nous avons l’avantage de tirer des enseignements des expériences de ceux qui se trouvent en Chine, en Europe et dans les Amériques. Ce document présente des conseils pour traiter nos patients atteints d’insuffisance rénale aiguë et chronique, y compris ceux sous thérapie de suppléance rénale et le personnel impliqué dans leurs soins. L’accent est mis sur les stratégies de préparation et de prévention. Au fur et à mesure que les preuves et l’expérience s’accumulent, il est probable que des directives actualisées seront nécessaires.
    Keywords COVID-19 ; Africa ; dialysis ; transplantation ; acute kidney injury ; covid19
    Language English
    Publishing date 2020-06-09
    Publisher African Association of Nephrology
    Publishing country za
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Correction

    Elsayed, Hesham M / Wadee, Shoyab / Zaki, Mohamed S / Were, Anthony JO / Ashuntantang, Gloria E / Bamgboye, Ebun L / Davids, Mogamat Razeen / Hafez, Mohamed H / Mahamat, Maimouna / Naicker, Saraladevi / Niang, Adbou / Seck, Sidy M / Swanepoel, Charles R / Tannor, Elliot K / Twahir, Ahmed / Yao, K Hubert

    African Journal of Nephrology; Vol 23, No; 151 ; 2518-4601 ; 2306-8205

    Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa

    2020  Volume 1

    Abstract: The authors of the article ‘Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa’ [1] wish to acknowledge the contribution of Professor Hussein El Fishawy. Our guidelines drew on various sources, ... ...

    Abstract The authors of the article ‘Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa’ [1] wish to acknowledge the contribution of Professor Hussein El Fishawy. Our guidelines drew on various sources, including the Egyptian Ministry of Health guidelines, portions of which were adapted and reproduced with permission from the Egyptian Ministry of Health. Two of the authors of those guidelines, Professors Elsayed and Zaki, are also coauthors of our paper. Professor El Fishawy was the third author of the Egyptian guidelines and we would like to acknowledge his contribution to our review through this source, especially with respect to the treatment algorithms for patients with kidney transplants and those with acute kidney injury. Reference1. Elsayed HM, Wadee S, Zaki MS, Were AJO, Ashuntantang GE, Bamgboye EL, et al. Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa. Afr J Nephrol. 2020; 23(1):109-126.
    Keywords covid19
    Subject code 380
    Language English
    Publishing date 2020-02-10
    Publisher African Association of Nephrology
    Publishing country za
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Closing the gap between evidence and practice in chronic kidney disease.

    Jardine, Meg J / Kasiske, Bertram / Adu, Dwomoa / Alrukhaimi, Mona / Ashuntantang, Gloria E / Basnet, Shakti / Chailimpamontree, Worawon / Craig, Jonathan C / O'Donoghue, Donal J / Perkovic, Vlado / Powe, Neil R / Roberts, Charlotte J / Suzuki, Yusuke / Tanaka, Tetsuhiro / Uhlig, Katrin

    Kidney international supplements

    2017  Volume 7, Issue 2, Page(s) 114–121

    Abstract: There are major gaps between our growing knowledge of effective treatments for chronic kidney disease (CKD), and the delivery of evidence-based therapies to populations around the world. Although there remains a need for new, effective therapies, current ...

    Abstract There are major gaps between our growing knowledge of effective treatments for chronic kidney disease (CKD), and the delivery of evidence-based therapies to populations around the world. Although there remains a need for new, effective therapies, current evidence suggests that many patients with CKD are yet to fully realize the benefits of blood pressure-lowering drugs (with and without reducing proteinuria with renin-angiotensin system blockade), wider use of statins to reduce atherosclerotic cardiovascular disease events, and better glycemic control in both type 1 and type 2 diabetes. There are many barriers to optimizing evidence-based nephrology care around the world, including access to health care, affordability of treatments, consumer attitudes and circumstances, the dissemination of appropriate knowledge, the availability of expertise and structural impediments in the delivery of health care. Further investment in implementation science that addresses the major barriers to effective care in a cost-effective manner could yield both local and global benefits.
    Language English
    Publishing date 2017-09-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 193442-9
    ISSN 2157-1716 ; 2157-1724 ; 0098-6577
    ISSN (online) 2157-1716
    ISSN 2157-1724 ; 0098-6577
    DOI 10.1016/j.kisu.2017.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Guidelines, policies, and barriers to kidney care: findings from a global survey.

    Lunney, Meaghan / Alrukhaimi, Mona / Ashuntantang, Gloria E / Bello, Aminu K / Bellorin-Font, Ezequiel / Benghanem Gharbi, Mohammed / Jha, Vivekanand / Johnson, David W / Kalantar-Zadeh, Kamyar / Kazancioglu, Rumeyza / Olah, Michelle E / Olanrewaju, Timothy Olusegun / Osman, Mohamed A / Parpia, Yasin / Perl, Jeffrey / Rashid, Harun Ur / Rateb, Ahmed / Rondeau, Eric / Sola, Laura /
    Tchokhonelidze, Irma / Tonelli, Marcello / Wiebe, Natasha / Wirzba, Isaac / Yang, Chih-Wei / Ye, Feng / Zemchenkov, Alexander / Zhao, Ming-Hui / Levin, Adeera

    Kidney international supplements

    2018  Volume 8, Issue 2, Page(s) 30–40

    Abstract: An international survey led by the International Society of Nephrology in 2016 assessed the current capacity of kidney care worldwide. To better understand how governance and leadership guide kidney care, items pertinent to government priority, advocacy, ...

    Abstract An international survey led by the International Society of Nephrology in 2016 assessed the current capacity of kidney care worldwide. To better understand how governance and leadership guide kidney care, items pertinent to government priority, advocacy, and guidelines, among others, were examined. Of the 116 responding countries, 36% (
    Language English
    Publishing date 2018-01-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 193442-9
    ISSN 2157-1716 ; 2157-1724 ; 0098-6577
    ISSN (online) 2157-1716
    ISSN 2157-1724 ; 0098-6577
    DOI 10.1016/j.kisu.2017.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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