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Article ; Online: Environmental Knowledge as a Mediator between Green Price, Green Promotion and Consumer Buying Behavior in Hypermarkets of UAE

Asim Mehmood / Amiya Bhaumik

SAR Journal, Vol 6, Iss 2, Pp 101-

2023 Volume 109

Abstract: This paper investigates the mediating role of environmental knowledge and its effect on green pricing, promotion, and consumer buying behaviour in hypermarkets in Ajman, UAE. Two hundred twenty questionnaires were distributed to hypermarket customers, ... ...

Abstract	This paper investigates the mediating role of environmental knowledge and its effect on green pricing, promotion, and consumer buying behaviour in hypermarkets in Ajman, UAE. Two hundred twenty questionnaires were distributed to hypermarket customers, with a return rate of 76.8%. The study utilized SPSS version 28 to conduct exploratory factor analysis on 21 items, focusing on item loading, convergent validity, and internal consistency. Correlation tests were performed to determine the strength of associations between variables, and multiple regression and mediation analysis was used to test the hypothesis. The results found that green pricing substantially affects consumer buying behaviour and environmental knowledge. The results showed that green promotion considerably impacts consumer buying behaviour and ecological knowledge. Additionally, environmental knowledge partly mediated the connection between green prices and CBB and green promotion and CBB. However, the study's findings are limited to Ajman, UAE, and cannot be generalized.
Keywords	environmental knowledge (ek) ; green price ; green promotion ; consumer buying behaviour (cbb) ; uae ; Science ; Q
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	UIKTEN
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prevalence of post-vaccine side effects among COVID-19 immunized community of Southern Pakistan.

Ali Qureshi / Syed Azhar Syed Sulaiman / Wajiha Rehman / Asim Mehmood / Sumaira Idrees / Narendar Kumar

PLoS ONE, Vol 18, Iss 5, p e

2023 Volume 0285736

Abstract: Background The response to the vaccine may vary among individuals. Hence, it is important to know how often individuals experience side effects after immunization against COVID-19. Objective This study aimed to assess the incidence of side effects ... ...

Abstract	Background The response to the vaccine may vary among individuals. Hence, it is important to know how often individuals experience side effects after immunization against COVID-19. Objective This study aimed to assess the incidence of side effects following COVID-19 vaccination across different vaccine recipients in Southern Pakistan and identify the potential factors associated with these side effects in the population. Methods The survey was conducted across Pakistan through Google-forms Links from August to October 2021. The questionnaire included demographic information and COVID-19 vaccine information. Chi-square (x2) was performed for comparative analysis to check the significance level with P <0.05. The final analysis included 507 participants who had received COVID-19 vaccines. Results Of the total 507 COVID-19 vaccines recipients, 24.9% received CoronaVac, 36.5% received BBIBP-CorV, 14.2% received BNT162b2, 13.8% received AZD1222, and 10.7% received mRNA-1273. The most prominent side effects after the first dose were fever, weakness, lethargy, and pain at the site of injection. Moreover, the most commonly reported side effects after the second dose were pain at the injection site, headache, body ache, lethargy, fever, chills, flu-like symptoms, and diarrhea. Conclusion Our results suggested that the side effects due to COVID-19 vaccination can vary between the first and second doses and type of COVID-19 vaccine. Our findings suggest continuing monitoring of vaccine safety and the importance of individualized risk-benefit assessment for COVID-19 immunization.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
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Article: A Randomized Control Trial Comparing the Efficacy of Platelet-Rich Plasma and 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia.

Asim, Mehmood / Shah, Rohan / Sharif, Shawana / Ouellette, Samantha / Shah, Amar / Rao, Babar

Journal of drugs in dermatology : JDD

2023 Volume 22, Issue 9, Page(s) 905–909

Abstract: Androgenetic alopecia (AGA) is the most common cause of hair loss in men and has limited treatment options. Minoxidil is a common therapeutic option for AGA patients because of its availability. Platelet-rich plasma (PRP) therapy is a newer option in AGA ...

Abstract	Androgenetic alopecia (AGA) is the most common cause of hair loss in men and has limited treatment options. Minoxidil is a common therapeutic option for AGA patients because of its availability. Platelet-rich plasma (PRP) therapy is a newer option in AGA management with promising results that may be suitable for some patients. Despite a great prevalence of AGA outside the United States and Europe, there remains limited studies on the efficacy of PRP for AGA treatment. Our study's objective was to compare the efficacy of PRP and minoxidil therapy for the treatment of AGA in a Pakistani population. 72 patients were included in this randomized control trial and were either treated with PRP or topical minoxidil. After 12 weeks of treatment, the hair pull test was performed and extracted hair was counted. We report a 91.7% negative hair pull rate in the PRP treatment group which was significantly greater than the 69.4% negative hair pull rate in the minoxidil-treated group. Our study suggests that PRP therapy demonstrates a higher efficacy compared to minoxidil for treating AGA, especially in our patient demographic. These results have the opportunity to improve patient compliance and overall satisfaction while offering an improved option in patients unsatisfied with topical minoxidil. Citation: Shah R, Asim M, Ouellette S, et al. A randomized control trial comparing the efficacy of platelet-rich plasma and 5% topical minoxidil for the treatment of androgenetic alopecia. J Drugs Dermatol. 2023;22(9):905-909. doi:10.36849/JDD.7031.
MeSH term(s)	Humans ; Male ; Alopecia/drug therapy ; Hair ; Minoxidil/therapeutic use ; Platelet-Rich Plasma
Chemical Substances	Minoxidil (5965120SH1)
Language	English
Publishing date	2023-09-08
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2145090-0
ISSN	1545-9616
ISSN	1545-9616
DOI	10.36849/JDD.7031
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Article ; Online: Inpatient Case-mix Cost Vs Average Cost for Health Care Services in King Fahd Central Hospital, Saudi Arabia

Asim Mehmood / Zafar Ahmed / Khalid Ghilan / Ahmed Damad / Fahad Khan Azeez

Inquiry: The Journal of Health Care Organization, Provision, and Financing, Vol

A Comparative Study

2021 Volume 58

Abstract: Health care systems aim to deliver high-quality medical care while considering efficient resource usage and cost-effective forms of interventions. Such purposes require scientific tools or mechanisms which aid in cost assessment before the efforts of ... ...

Abstract	Health care systems aim to deliver high-quality medical care while considering efficient resource usage and cost-effective forms of interventions. Such purposes require scientific tools or mechanisms which aid in cost assessment before the efforts of cost reduction are considered. Diagnosis-related groups based costing methodology (Case-mix) is considered one of the preferred costing approaches in the health care sector. King Fahd Central hospital Jazan, the only tertiary hospital in the Jazan region, was selected for case-mix system-based patient-level costing of health services. The study’s objective was to estimate the cost per Diagnosis-Related Group (DRG) per inpatient admission and compare it with the already established average cost of health care services for inpatients. We applied a cross-sectional retrospective approach to categorize the inpatients based on their diagnosis and procedures and then estimate the actual cost of health care services provided to inpatients during 2018 and compared it with the average cost of the health services. There was a considerable difference between DRG-based costing (SAR 269,663,897) and average costing (SAR 247,035,938). The Diagnosis Related Group costing was found to be more reliable and representative of the services provided to the patients and is recommended to be used for reimbursement purposes.
Keywords	Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
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Article ; Online: Development of unit cost for the health services offered at King FAHD Central hospital Jazan, Saudi Arabia

Khalid Ghilan / Asim Mehmood / Zafar Ahmed / Ahmed Nahari / Mohammed J. Almalki / Abdulrahman M. Jabour / Fahad khan

Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 643-

2021 Volume 650

Abstract: Background: Efficiency remains one of the most important drivers of decision making in health care system. Fund allocators need to receive structured information about the cost healthcare services from hospitals for better decisions related to resource ... ...

Abstract	Background: Efficiency remains one of the most important drivers of decision making in health care system. Fund allocators need to receive structured information about the cost healthcare services from hospitals for better decisions related to resource allocation and budgeting. The objective of the study was to estimate the unit cost for health services offered to inpatients in King Fahd Central hospital (KFCH) Jazan during the financial year 2018. Methods: We applied a retrospective approach using a top-down costing method to estimate the cost of health care services. Clinical and Administrative departments divided into cost centres, and the unit cost was calculated by dividing the total cost of final care cost centres into the total number of patients discharged in one year. The average cost of inpatient services was calculated based on the average cost of each ward and the number of patients treated. Results: The average cost per patient stayed in KFCH was SAR 19,034, with the highest cost of SAR 108,561 for patients in the Orthopedic ward. The average cost of the patient in the Surgery ward, Plastic surgery, Neurosurgery, Medical ward, Pediatric ward and Gynecology ward was SAR 33,033, SAR 29,425, SAR 23,444, SAR 20,450, SAR 9579 and SAR 8636 respectively. Conclusion: This study provides necessary information about the cost of health care services in a tertiary care setting. This information can be used as a primary tool and reference for further studies in other regions of the country. Hence, this data can help to provide a better understanding of tertiary hospital costing in the region to achieve the privatization objective.
Keywords	Hospital costing ; Health economics ; Patient-level costing ; Saudi Arabia ; Tertiary Hospital ; Top-down costing ; Biology (General) ; QH301-705.5
Subject code	360
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway

Partha Biswas / Shabana Bibi / Qudsia Yousafi / Asim Mehmood / Shahzad Saleem / Awais Ihsan / Dipta Dey / Md. Nazmul Hasan Zilani / Md. Nazmul Hasan / Rasha Saleem / Aeshah A. Awaji / Usama A. Fahmy / Mohamed M. Abdel-Daim

Molecules, Vol 28, Iss 2977, p

A Computational Drug Development Approach

2023 Volume 2977

Abstract: An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several transcriptome servers were used to measure the differential expression of the ... ...

Abstract	An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several transcriptome servers were used to measure the differential expression of the targeted MDM2 gene and search mutations and copy number variations. GENT2, Gene Expression Profiling Interactive Analysis, Onco-Lnc, and PrognoScan were used to figure out the survival rate of LGG cancer patients. The protein–protein interaction networks between MDM2 gene and its co-expressed genes were constructed by Gene-MANIA tool. Identified bioactive phytochemicals were evaluated through molecular docking using Schrödinger Suite Software, with the MDM2 (PDB ID: 1RV1) target. Protein–ligand interactions were observed with key residues of the macromolecular target. A molecular dynamics simulation of the novel bioactive compounds with the targeted protein was performed. Phytochemicals targeting MDM2 protein, such as Taxifolin and (-)-Epicatechin, have been shown with more highly stable results as compared to the control drug, and hence, concluded that phytochemicals with bioactive potential might be alternative therapeutic options for the management of LGG patients. Our once informatics-based designed pipeline has indicated that the MDM2 gene may have been a predictive biomarker for LGG cancer and selected phytochemicals possessed outstanding interaction results within the macromolecular target’s active site after utilizing in silico approaches. In vitro and in vivo experiments are recommended to confirm these outcomes.
Keywords	p53 gene ; MDM2 gene ; onco-informatics ; brain lower-grade glioma (LGG) cancer ; predictive biomarker ; Organic chemistry ; QD241-441
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Terpinen-4-ol from Trachyspermum ammi is a potential and safer candidate molecule for fungicide development against Alternaria solani

Qudsia Yousafi / Muhammad Sohail Shahzad / Shahzad Saleem / Muhammad Wasim Sajid / Abrar Hussain / Asim Mehmood / Allah Ditta Abid / Amina Qandeel / Anum Shahid / Muhammad Saad Khan / Sania Mazhar / Ahmed Ezzat Ahmed / Khalid M. Al Syaad

Journal of King Saud University: Science, Vol 34, Iss 1, Pp 101747- (2022)

2022

Abstract: Phytopathogenic fungi are serious threats to fruit and vegetable production. Use of plant essential oil (PEO), as antifungal agents, have been in practice for many years. Essential oils (EO) of five plants i.e., Trachyspermum ammi, Cuminum cyminum, ... ...

Abstract	Phytopathogenic fungi are serious threats to fruit and vegetable production. Use of plant essential oil (PEO), as antifungal agents, have been in practice for many years. Essential oils (EO) of five plants i.e., Trachyspermum ammi, Cuminum cyminum, Azadirachta indica, Citrus sinensis and Eucalyptus grandis were tested against Alternaria solani in tomato. The trials consisted of laboratory testing (MIC and MFC), field testing and Computer Aided Fungicide Design (CAFD) of PEOs against A. solani. Each PEO was used at 10 and 25 µl/ml concentrations to asses MIC, while MFC was assessed at 25, 50 and 75µl/ml concentration. Trachyspermum ammi EO at 25µl/ml concentration showed the largest inhibition zone (37.3 mm) followed by a not significantly different zone(20.6 mm)produced by C. cyminum EO. No fungal growth was observed at 50µl/ml concentration of T. ammi while, at 75µl/ml for A. indica and C. cyminum. In foliar application, T. ammi EO showed lowest percent disease incidence (2.2) which was not significantly different from that of C. cyminum. Trachyspermum ammi EO, qualified in laboratory and field trials, was selected for CAFD. Compounds of T. ammi PEO docked against toxin producing enzyme, solanapyrone synthase, of A. solani. Terpinen-4-ol was qualified as a lead compound against A. solani.
Keywords	Computer Aided Fungicide Design ; Percent Disease Incidence ; Minimum Inhibitory Concentration ; Minimum Fungicidal Concentration ; MD Simulation ; Science (General) ; Q1-390
Subject code	571
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Assessment of Wastewater Quality of Drains for Irrigation

Almas Hamid / Mahrukh Zeb / Asim Mehmood / Sana Akhtar / Samia Saif

Journal of Environmental Protection , Vol 04, Iss 09, Pp 937-

2013 Volume 945

Abstract: Rapid industrialization and overpopulation ha ve stimulated increase in waste water both domestic and industrial. Due to lack of inefficient sewerage system and absence of treatment plants, the wastewater is discharged into drainage systems causing ... ...

Abstract	Rapid industrialization and overpopulation ha ve stimulated increase in waste water both domestic and industrial. Due to lack of inefficient sewerage system and absence of treatment plants, the wastewater is discharged into drainage systems causing environmental and health implications. At various points, the wastewater of these drains is used for irrigation purposes. This study characterizes the effluent of major drains of Lahore city and assesses its suitability for irrigation. Wastewater samples were collected from drains in winter and spring seasons and analyzed for various parameters of special concern to irrigation. TSS, oil and grease, BOD, COD, chloride, TDS, sodium, SAR, bicarbonate ions, EC, iron, Copper and Nickel were found to be varied in concentration in different drains when compared with NEQS (National Environment Quality Standards) and FAO guidelines for irrigation in both seasons. Regular monitoring and proper treatment of wastewater before discharging into the drains can reduce the pollution in these drains.
Keywords	Industrialization ; Wastewater Quality ; Drains ; Irrigation ; Winter and Spring Season ; FAO Guidelines ; Environmental sciences ; GE1-350 ; Geography. Anthropology. Recreation ; G ; DOAJ:Environmental Sciences ; DOAJ:Earth and Environmental Sciences
Subject code	333
Language	English
Publishing date	2013-08-01T00:00:00Z
Publisher	Scientific Research Publishing
Document type	Article ; Online
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Article ; Online: Molecular analysis of V617F mutation in Janus kinase 2 gene of breast cancer patients

Sajjad Karim / Imran Riaz Malik / Quratulain Nazeer / Ahmad Zaheer / Muhammad Farooq / Nasir Mahmood / Arif Malik / Muhammad Asif / Asim Mehmood / Abdul Rehman Khan / Abdul Jabbar / Muhammad Arshad / Qudsia yousafi / Abrar Hussain / Zeenat Mirza / Muhammad Atif Iqbal / Mahmood Rasool

Saudi Journal of Biological Sciences, Vol 26, Iss 6, Pp 1123-

2019 Volume 1128

Abstract: Background: Breast cancer is a multifactorial disease with the highest frequency in females. Genetic and environmental factors can cause mutation in several genes like tyrosine kinase, JAK2 gene which may initiate cancer. Molecular analysis of mutations ... ...

Abstract	Background: Breast cancer is a multifactorial disease with the highest frequency in females. Genetic and environmental factors can cause mutation in several genes like tyrosine kinase, JAK2 gene which may initiate cancer. Molecular analysis of mutations in the JAK2 gene along with determination of environmental, clinical and haematological risk factors associated with breast cancer patients is need of hour to improve patient's healthcare. Somatic JAK2 valine-to-phenylalanine (617 codon) mutation is one of the widely prevalent mutations. Methods: Blood was collected from seventy breast cancer patients after their consent. The questionnaire included risk factors, age group, locality, number of children, tumor type, family history, time of initial diagnosis, no of cycles/month, water conditions and exposure to radiations. Molecular analysis were carried out from genomic DNA using Sanger sequencing and allele-specific PCR to check the V617F point mutation. Results: The breast cancer risk factors includes unfiltered water (68.57%), urban (58.57%), menopause (55.71%), family history of cancer (18.57%), tumor grades (II, 37.14% and III, 35.71%), consanguineous marriages (44.28%) and having more than 3–4 children (45.71%). Prevalence of breast cancer was higher after the age of 35 and maximum at 35–50. In allele-specific PCR of 70 patients, 25 patients were wild type (229 bp), 25 patients were with partially deleted gene (200 bp), and 20 patient had shown no or less than 40 bp size fragments. In Sanger's sequencing of 70 BC cases, 18% were found to be positive for V617F point mutation, including 6 homozygous (T/T) and 7 heterozygous (G/T) mutations at nucleotide position 1849 in exon 14 of the JAK2 gene. Conclusions: Environmental and clinical risk factors were associated with breast cancer which can be overcome by improving awareness of associated risks, health facilities and reducing stress. Keywords: Breast cancer, JAK2, V617F mutation, Allele-specific PCR, Sanger’s sequencing
Keywords	Biology (General) ; QH301-705.5
Subject code	610 ; 616
Language	English
Publishing date	2019-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Physical and chemical mutagens improved Sporotrichum thermophile, strain ST20 for enhanced Phytase activity

Asim Mehmood / Umal Baneen / Ahmad Zaheer / Muhammad Wasim Sajid / Abrar Hussain / Shahzad Saleem / Qudsia Yousafi / Hamid Rashid / Hassan Riaz / Awais Ihsan / Farrukh Jamil / Yasar Sajjad / Nageena Zahid / Muhammad Shahzad Anjam / Muhammad Arshad / Zeenat Mirza / Sajjad Karim / Mahmood Rasool

Saudi Journal of Biological Sciences, Vol 26, Iss 7, Pp 1485-

2019 Volume 1491

Abstract: Objective: Phosphorous is an essential micronutrient of plants and involved in critical biological functions. In nature, phosphorous is mostly present in immobilized inorganic mineral and in the fixed organic form including phytic acid and phosphoesteric ...

Abstract	Objective: Phosphorous is an essential micronutrient of plants and involved in critical biological functions. In nature, phosphorous is mostly present in immobilized inorganic mineral and in the fixed organic form including phytic acid and phosphoesteric compounds. However, the bioavailability of bound phosphorous could be enhanced by the use of phosphate solubilizing microorganisms such as bacteria and fungi. The phytases are widespread in an environment and have been isolated from different sources comprising bacteria and fungi. Methodology: In current studies, we show the successful use of gamma rays and EMS (Ethyl Methane Sulphonate) mutagenesis for enhanced activity of phytases in a fungal strain Sporotrichum thermophile. Results: We report an improved strain ST2 that could produce a clear halo zone around the colony, up to 24 mm. The maximum enzymatic activity was found of 382 U/mL on pH 5.5. However, the phytase activity was improved to 387 U/ml at 45 °C. We also report that the mutants produced through EMS showed the greater potential for phytase production. Conclusion: The current study highlights the potential of EMS mutagenesis for strain improvement over physical mutagens. Keywords: Gamma rays, EMS mutagenesis, Fungus, Phosphate solubilizer
Keywords	Biology (General) ; QH301-705.5
Language	English
Publishing date	2019-11-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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