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  1. Article ; Online: The sodium pump and digitalis drugs: Dogmas and fallacies.

    Askari, Amir

    Pharmacology research & perspectives

    2019  Volume 7, Issue 4, Page(s) e00505

    Abstract: The sodium pump (Na/K-ATPase) is a plasma membrane enzyme that transports ... ...

    Abstract The sodium pump (Na/K-ATPase) is a plasma membrane enzyme that transports Na
    MeSH term(s) Animals ; Digitalis Glycosides/pharmacology ; Digitalis Glycosides/therapeutic use ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Humans ; Myocardial Contraction/drug effects ; Signal Transduction/drug effects ; Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors
    Chemical Substances Digitalis Glycosides ; Sodium-Potassium-Exchanging ATPase (EC 7.2.2.13)
    Language English
    Publishing date 2019-07-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2740389-0
    ISSN 2052-1707 ; 2052-1707
    ISSN (online) 2052-1707
    ISSN 2052-1707
    DOI 10.1002/prp2.505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The other functions of the sodium pump.

    Askari, Amir

    Cell calcium

    2019  Volume 84, Page(s) 102105

    Abstract: Na/K-ATPase (the sodium pump) was discovered in the 1950s as the plasma membrane enzyme that carries out the coupled active transports of ... ...

    Abstract Na/K-ATPase (the sodium pump) was discovered in the 1950s as the plasma membrane enzyme that carries out the coupled active transports of Na
    MeSH term(s) Animals ; Cardiomegaly/metabolism ; Cell Membrane/metabolism ; ErbB Receptors/metabolism ; Humans ; Myocardium/metabolism ; Myocytes, Cardiac/physiology ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Sodium-Potassium-Exchanging ATPase/genetics ; Sodium-Potassium-Exchanging ATPase/metabolism
    Chemical Substances EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1) ; Sodium-Potassium-Exchanging ATPase (EC 7.2.2.13)
    Language English
    Publishing date 2019-11-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2019.102105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1596: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Comment on: Outcomes after totally minimally invasive versus hybrid and open Ivor Lewis oesophagectomy: Results from the International Esodata Study Group.

    Askari, Alan / Jayanthi, Naga Venkatesh Gupta

    The British journal of surgery

    2022  Volume 109, Issue 9, Page(s) e99

    MeSH term(s) Esophageal Neoplasms/surgery ; Esophagectomy/methods ; Humans ; Laparoscopy/methods ; Minimally Invasive Surgical Procedures/methods ; Postoperative Complications/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-05-10
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znac143
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  4. Article: Kulturbedingte Herausforderungen für Paare im Iran heute

    Askari, Amir

    Verhaltenstherapie & psychosoziale Praxis

    2020  Volume 52, Issue 4, Page(s) 785

    Language German
    Document type Article
    ZDB-ID 627290-3
    ISSN 0721-7234
    Database Current Contents Medicine

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  5. Article: Kulturbedingte Herausforderungen für Paare im Iran heute

    Askari, Amir

    Verhaltenstherapie und psychosoziale Praxis

    2020  Volume 52, Issue 4, Page(s) 785–795

    Abstract: Kulturelle Besonderheiten bei der schematherapeutischen Arbeit mit Paaren in einem islamischen Land wie dem Iran werden dargestellt. Nach einer kurzen Einleitung zur historischen Entwicklung von Ehe- und Partnerschaftsformen im Iran werden zu folgenden ... ...

    Title translation Cultural challenges for couples in Iran today
    Abstract Kulturelle Besonderheiten bei der schematherapeutischen Arbeit mit Paaren in einem islamischen Land wie dem Iran werden dargestellt. Nach einer kurzen Einleitung zur historischen Entwicklung von Ehe- und Partnerschaftsformen im Iran werden zu folgenden Problemfeldern typische Konflikte sowie die damit verbundenen Schemata und Modi beschrieben und in das besondere kulturelle Umfeld eingeordnet: (1) Traditionelle Rolle von Mann und Frau, (2) Einfluss der Eltern auf das Paar, (3) Familienplanung, (4) Einfluss der sozialen Medien, (5) Polygamie.
    Keywords Conflict ; Couples Therapy ; Cross Cultural Differences ; Cultural Sensitivity ; Eheberatung ; Family of Origin ; Herkunftsfamilie ; Interkulturelle Unterschiede ; Islam ; Konflikt ; Kulturelle Sensitivität ; Loyalität ; Loyalty ; Marriage Counseling ; Multicultural Counseling ; Multikulturelle Beratung ; Paartherapie ; Schema Therapy ; Schematherapie
    Language German
    Document type Article
    ZDB-ID 627290-3
    ISSN 0721-7234
    ISSN 0721-7234
    Database PSYNDEX

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  6. Article ; Online: Psychometric assessment of the Persian adaptation of the attitudes toward seeking professional psychological help scale-short form.

    Nazari, Abouzar / Garmaroudi, Gholamreza / Foroushani, Abbas Rahimi / Askari, Azadeh

    BMC psychiatry

    2024  Volume 24, Issue 1, Page(s) 75

    Abstract: Background and purpose: Mental health disorders are a growing concern worldwide, with a significant impact on public health. Understanding attitudes toward seeking professional psychological help is essential in addressing these issues. In the Iranian ... ...

    Abstract Background and purpose: Mental health disorders are a growing concern worldwide, with a significant impact on public health. Understanding attitudes toward seeking professional psychological help is essential in addressing these issues. In the Iranian context, there is a need for a reliable tool to measure these attitudes. This study aims to assess the validity and reliability of the Persian Adaptation of the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form (ATSPPH-SF).
    Materials and methods: A cross-sectional study was conducted in May 2023, utilizing a convenience sampling method with 1050 participants aged 10 to 65 years in Iran.The ATSPPH-SF questionnaire, consisting of 10 items and 2 subscales, was employed. The questionnaire underwent translation and cultural adaptation, and its validity was assessed through qualitative face and content validities. Confirmatory factor analysis (CFA) was used to evaluate construct validity. Reliability was assessed using McDonald's omega coefficient and Cronbach's alpha coefficient. Data collection was conducted through an online survey.
    Results: The CFA results indicated a two-factor structure for the ATSPPH-SF, with one factor representing openness to seeking treatment for emotional problems and the other factor reflecting the value and need for seeking treatment. The model demonstrated acceptable fit indices. Both McDonald's omega coefficient and Cronbach's alpha coefficient suggested good internal consistency for the scale. The mean total score for the ATSPPH-SF was 21.37 (SD = 5.52), indicating the reliability and validity of the scale for the Iranian population.
    Conclusion: This study confirms the suitability of the short-form ATSPPH-SF with 10 items and 2 subscales as a valid and reliable tool for assessing attitudes toward seeking professional psychological help in the Iranian population. With no prior appropriate instrument available, this scale fills a crucial gap. It can be employed to measure attitudes among various demographic groups, aiding in the design of targeted interventions to enhance mental health literacy and reduce the stigma associated with seeking professional psychological help in Iran.
    MeSH term(s) Humans ; Psychometrics/methods ; Cross-Sectional Studies ; Iran ; Reproducibility of Results ; Surveys and Questionnaires
    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-023-05388-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comparative study of operative expenses: robotic vs. laparoscopic vs. open liver resections at a university hospital in the UK.

    Elshaer, Mohamed / Askari, Alan / Pathanki, Adithya / Rajani, Jaimini / Ahmad, Jawad

    Journal of robotic surgery

    2024  Volume 18, Issue 1, Page(s) 12

    Abstract: Robotic liver resections (RLR) are increasingly being performed and has previously been considered more costly. The aim is to explore the cost of RLR compared with laparoscopic and open liver resection in a single National Health Service (NHS) hospital. ... ...

    Abstract Robotic liver resections (RLR) are increasingly being performed and has previously been considered more costly. The aim is to explore the cost of RLR compared with laparoscopic and open liver resection in a single National Health Service (NHS) hospital. A retrospective review of patients who underwent RLR, LLR, and OLR from April 2014 to December 2022 was conducted. The primary outcomes were the cost of consumables and median income, and the secondary outcomes were the overall length of stay and mortality at 90 days. Overall, 332 patients underwent liver resections. There were 204 males (61.4%) and 128 females (38.6%), with a median age of 62 years (IQR: 51-77 years). Of these, 60 patients (18.1%) underwent RLR, 21 patients (6.3%) underwent LLR, and 251 patients (75.6%) underwent OLR. Median consumables cost per case was £3863 (IQR: £3458-£5061) for RLR, £4326 (IQR: £4273-£4473) for LLR, and £4,084 (IQR: £3799-£5549) for the OLR cohort (p = 0.140). Median income per case was £7999 (IQR: £4509-£10,777) for RLR, £7497 (IQR: £2407-£14,576) for LLR, and £7493 (IQR: £2542-£14,121) for OLR. The median length of stay (LOS) for RLR was 3 days (IQR: 2-4.7 days) compared to 5 days for LLR (IQR: 4.5-7 days) and 6 days for OLR (IQR: 5-8 days, p < 0.001). Within the NHS, RLR has consumable costs comparable to OLR and LLR. It is also linked with a shorter LOS and generates similar income for patients undergoing OLR and LLR.
    MeSH term(s) Male ; Female ; Humans ; Middle Aged ; Aged ; Liver Neoplasms/surgery ; Robotic Surgical Procedures/methods ; State Medicine ; Laparoscopy ; Hepatectomy ; Length of Stay ; Retrospective Studies ; Hospitals ; United Kingdom ; Carcinoma, Hepatocellular/surgery ; Postoperative Complications/surgery
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-023-01778-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Comparison of virulence factors between ESBL and non-ESBL producing

    Mirbag, Hamed Hatami / Tajbakhsh, Saeed / Askari, Azam / Yousefi, Forough

    Iranian journal of microbiology

    2024  Volume 16, Issue 1, Page(s) 39–48

    Abstract: Background and objectives: Klebsiella pneumoniae: Materials and methods: A total of 113 : Results: There was no statistically significant difference in enzymatic profile between ESBL and non-ESBL producers. The prevalence of the hypermocoviscosity ...

    Abstract Background and objectives: Klebsiella pneumoniae
    Materials and methods: A total of 113
    Results: There was no statistically significant difference in enzymatic profile between ESBL and non-ESBL producers. The prevalence of the hypermocoviscosity was lower among ESBL compared to non-ESBL producers but the intensity of biofilm was higher in the ESBL producers. Among the virulence genes,
    Conclusion: The identification of potentially pathogenic isolates plays an important role in preventing their spread as well as the success of their treatment.
    Language English
    Publishing date 2024-04-25
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2652849-6
    ISSN 2008-4447 ; 2008-3289
    ISSN (online) 2008-4447
    ISSN 2008-3289
    DOI 10.18502/ijm.v16i1.14869
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  9. Article ; Online: Acute Irreducible Rotational Patellar Dislocation with Patellar Tendon Rupture: A Case Report.

    Askari, Alireza / Jabalameli, Mahmoud / Arasteh, Peyman / Kassir, Hassan

    JBJS case connector

    2023  Volume 13, Issue 3

    Abstract: Case: In this report, we present a case of acute patellar dislocation with both vertical and longitudinal rotation of the patella. As a result of rotation in the longitudinal axis, the articular surface of the patella faced outward, and the dorsal ... ...

    Abstract Case: In this report, we present a case of acute patellar dislocation with both vertical and longitudinal rotation of the patella. As a result of rotation in the longitudinal axis, the articular surface of the patella faced outward, and the dorsal surface faced the femoral condyle. The patient underwent open reduction. One year after open reduction and soft-tissue repair, the patient had acceptable knee function and no knee pain.
    Conclusion: This case shows how similar cases may be treated with an open reduction to properly address the patellar dislocation.
    MeSH term(s) Humans ; Patellar Dislocation/diagnostic imaging ; Patellar Dislocation/surgery ; Patella/diagnostic imaging ; Patella/surgery ; Patellar Ligament/diagnostic imaging ; Patellar Ligament/surgery ; Joint Dislocations ; Knee Injuries ; Tendon Injuries
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI 10.2106/JBJS.CC.23.00058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Augmenting interpretable models with large language models during training.

    Singh, Chandan / Askari, Armin / Caruana, Rich / Gao, Jianfeng

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 7913

    Abstract: Recent large language models (LLMs), such as ChatGPT, have demonstrated remarkable prediction performance for a growing array of tasks. However, their proliferation into high-stakes domains and compute-limited settings has created a burgeoning need for ... ...

    Abstract Recent large language models (LLMs), such as ChatGPT, have demonstrated remarkable prediction performance for a growing array of tasks. However, their proliferation into high-stakes domains and compute-limited settings has created a burgeoning need for interpretability and efficiency. We address this need by proposing Aug-imodels, a framework for leveraging the knowledge learned by LLMs to build extremely efficient and interpretable prediction models. Aug-imodels use LLMs during fitting but not during inference, allowing complete transparency and often a speed/memory improvement of greater than 1000x for inference compared to LLMs. We explore two instantiations of Aug-imodels in natural-language processing: Aug-Linear, which augments a linear model with decoupled embeddings from an LLM and Aug-Tree, which augments a decision tree with LLM feature expansions. Across a variety of text-classification datasets, both outperform their non-augmented, interpretable counterparts. Aug-Linear can even outperform much larger models, e.g. a 6-billion parameter GPT-J model, despite having 10,000x fewer parameters and being fully transparent. We further explore Aug-imodels in a natural-language fMRI study, where they generate interesting interpretations from scientific data.
    MeSH term(s) Learning ; Knowledge ; Language ; Linear Models ; Natural Language Processing
    Language English
    Publishing date 2023-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-43713-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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