Article ; Online: Seroprevalence and risk factors for Toxoplasma gondii infection among pregnant women at Debre Markos Referral Hospital, northwest Ethiopia.
Transactions of the Royal Society of Tropical Medicine and Hygiene
2023 Volume 118, Issue 1, Page(s) 61–68
Abstract: Background: To assess the seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women at the Debre Markos Referral Hospital, northwest Ethiopia.: Methods: A facility-based cross-sectional study was undertaken among pregnant women ...
| Abstract | Background: To assess the seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women at the Debre Markos Referral Hospital, northwest Ethiopia. Methods: A facility-based cross-sectional study was undertaken among pregnant women from March 2020 to May 2021. Sociodemographic and clinical data were collected from randomly selected participants. Five millilitres of blood was collected and an enzyme-linked immunosorbent assay kit was used to test for T. gondii immunoglobulin G (IgG) antibodies. A logistic regression model was computed to identify the risk factors. The adjusted odds ratio (aOR) was estimated along with the 95% confidence interval (CI). A statistically significant association was defined as p<0.05. Results: T. gondii IgG antibody positivity was found in 38.8% (n=132) of 340 pregnant women. Contact with cats (AOR 2.5 [95% CI 1.5 to 4.2]), eating raw/undercooked meat (AOR 5.7 [95% CI 3.2 to 10.3]), consuming unwashed vegetables (AOR 4.1 [95% CI 2.1 to 8.0]), a history of abortion (AOR 1.9 [95% CI 1.1 to 3.3]) and drinking water sources (AOR 2.5 [95% CI 1.2 to 5.2]) demonstrated a statistically significant association with T. gondii infection. Conclusions: Toxoplasmosis was found to be fairly common in pregnant mothers. Proper cat excreta disposal, not eating raw/undercooked meat, maintaining hand cleanliness and following environmental sanitation protocols could be important to decrease T. gondii infection. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Female ; Pregnancy ; Humans ; Animals ; Cats ; Toxoplasma ; Pregnant Women ; Seroepidemiologic Studies ; Ethiopia/epidemiology ; Cross-Sectional Studies ; Antibodies, Protozoan ; Toxoplasmosis/epidemiology ; Risk Factors ; Hospitals | |||||
| Chemical Substances | Antibodies, Protozoan | |||||
| Language | English | |||||
| Publishing date | 2023-08-11 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 441375-1 | |||||
| ISSN | 1878-3503 ; 0035-9203 | |||||
| ISSN (online) | 1878-3503 | |||||
| ISSN | 0035-9203 | |||||
| DOI | 10.1093/trstmh/trad053 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Un I Zs.257: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.