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  1. Book ; Conference proceedings: Colloque Européen Diabète Non Insulinodépendant: Maladie Métabolique et Vasculaire

    Assan, Roger

    26 mars 1994, Paris = An European Symposium Non Insulin Dependent Diabetes Mellitus, a Metabolic and Vascular Disease

    (Diabète & metabolisme ; 20,3 bis)

    1994  

    Title variant An European Symposium Non Insulin Dependent Diabetes Mellitus, a Metabolic and Vascular Disease ; Diabète non insulinodépendant: maladie métabolique et vasculaire
    Institution Institut Servier du Diabète
    Event/congress Colloque Européen Diabète Non Insulinodépendant: Maladie Métabolique et Vasculaire (1994, Paris)
    Author's details l'Institut Servier du Diabète. R. Assan ... éds. invités
    Series title Diabète & metabolisme ; 20,3 bis
    Keywords Diabetes Mellitus, Non-Insulin-Dependent / metabolism / congresses ; Diabetes Mellitus, Non-Insulin-Dependent / complications / congresses ; Cardiovascular Diseases / etiology / congresses
    Language French
    Size S. [313] - 374 : graph. Darst.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book ; Conference proceedings
    HBZ-ID HT006500423
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 1267 -20,3 bis- verfügbar in Königswinter Königswinter

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  2. Book: LES NEURO-HORMONES HYPOTHALAMIQUES

    Assan, Roger

    RAPPORTS PRES. AU 41. CONGRES FRANCAIS DE MEDECINE, PARIS, 1977

    1977  

    Title variant NEUROHORMONES HYPOTHALAMIQUES
    Author's details PAR R. ASSAN
    Keywords PITUITARY HORMONE-RELEASING HORMONES / CONGRESSES
    Size 136 S. ; 24 CM
    Publisher MASSON
    Publishing place PARIS (U.A.)
    Document type Book
    HBZ-ID HT000291163
    ISBN 2-225-47575-X ; 978-2-225-47575-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1978 A 2882 order for loan Magazin

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  3. Book: Métabolisme glucidique et sa régulation

    Assan, Roger

    (Actualités de physiologie pathologique ; 4)

    1973  

    Author's details (par R. Assan [u.a.])
    Series title Actualités de physiologie pathologique ; 4
    Collection
    Language French
    Size 6, 287 S. ; 8-o
    Publisher Masson
    Publishing place Paris
    Publishing country France
    Document type Book
    HBZ-ID HT011031991
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1983 A 2711 order for loan Magazin

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  4. Book ; Conference proceedings: Progres recents en immunopathologie

    Assan, Roger / Bach, Jean-François

    rapports pres. au XLV Congres Francais de Medecine, Paris, 1985

    1985  

    Event/congress Congres Francais de Medecine (45, 1985, Paris)
    Author's details par R. Assan ... Coordonnateur J. F. Bach
    Keywords Immunologic Diseases / congresses
    Size 119 S.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book ; Conference proceedings
    HBZ-ID HT002288409
    ISBN 2-225-80705-1 ; 978-2-225-80705-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1986 A 570 order for loan Magazin

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  5. Book: Glucagon / 3 / Contributors J. M. Amatruda ...

    Aoki, Thomas T. / Assan, Roger / Amatruda, John M. / Lefebvre, Pierre J.

    (Handbook of experimental pharmacology ; 123)

    1996  

    Author's details ed. Pierre J. Lefèbvre
    Series title Handbook of experimental pharmacology ; 123
    Glucagon
    Collection Glucagon
    Language English
    Size XX, 349 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin
    Document type Book
    HBZ-ID HT007279634
    ISBN 3-540-60989-X ; 978-3-540-60989-6
    Database Catalogue ZB MED Medicine, Health

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    2004 A 6639 order for loan Magazin
    1982 A 2146 -123- order for loan Magazin

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  6. Book: Glucagon / 2 / Contrib. R. Assan ...

    Aoki, Thomas T. / Assan, Roger / Amatruda, John M. / Lefebvre, Pierre J.

    (Handbook of experimental pharmacology ; 66,[2])

    1983  

    Author's details ed. Pierre J. Lefèbvre
    Series title Handbook of experimental pharmacology ; 66,[2]
    Glucagon
    Collection Glucagon
    Language English
    Size XXX, 700 S.
    Publisher Springer
    Publishing place Berlin
    Document type Book
    HBZ-ID HT002370155
    ISBN 3-540-12272-9 ; 0-387-12272-9 ; 978-3-540-12272-2 ; 978-0-387-12272-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2004 A 6550 order for loan Magazin
    1982 A 2146 -66,2- order for loan Magazin

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  7. Book: Glucagon / 1 / Contrib. T. T. Aoki ...

    Aoki, Thomas T. / Assan, Roger / Amatruda, John M. / Lefebvre, Pierre J.

    (Handbook of experimental pharmacology ; 66,[1])

    1983  

    Author's details ed. Pierre J. Lefèbvre
    Series title Handbook of experimental pharmacology ; 66,[1]
    Glucagon
    Collection Glucagon
    Language English
    Size XXVIII, 535 S.
    Publisher Springer
    Publishing place Berlin
    Document type Book
    HBZ-ID HT002370154
    ISBN 3-540-12068-8 ; 0-387-12068-8 ; 978-3-540-12068-1 ; 978-0-387-12068-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    1982 A 2146 -66,1- order for loan Magazin
    2004 A 6549 order for loan Magazin

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  8. Article: Normal insulin sensitivity during the late preclinical stage of type 1 diabetes.

    Larger, Etienne / Rakotoambinina, Benjamin / Eddouks, Mohammed / Timsit, José / Boitard, Christian / Assan, Roger / Burcelin, Rémy / Robert, Jean-Jacques / Rakotoaminina, Benjamin

    Diabetes care

    2004  Volume 27, Issue 7, Page(s) 1842–1843

    MeSH term(s) Blood Glucose/drug effects ; Blood Glucose/metabolism ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Disease Progression ; Glucose Clamp Technique ; Humans ; Insulin/pharmacology ; Insulin/therapeutic use ; Prediabetic State/blood ; Prediabetic State/physiopathology
    Chemical Substances Blood Glucose ; Insulin
    Language English
    Publishing date 2004-06-24
    Publishing country United States
    Document type Letter
    ZDB-ID 441231-x
    ISSN 1935-5548 ; 0149-5992
    ISSN (online) 1935-5548
    ISSN 0149-5992
    DOI 10.2337/diacare.27.7.1842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1434: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 365: Show issues

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  9. Article: Normal renal function 8 to 13 years after cyclosporin A therapy in 285 diabetic patients.

    Assan, Roger / Blanchet, Françoise / Feutren, Gilles / Timsit, José / Larger, Etienne / Boitard, Christian / Amiel, Claude / Bach, Jean-François

    Diabetes/metabolism research and reviews

    2002  Volume 18, Issue 6, Page(s) 464–472

    Abstract: Background: Cyclosporin A (CyA) may induce acute nephrotoxicity. The question has been raised of the possible long-term unfavorable course of CyA-induced lesions. Advantage was taken of a large cohort of diabetic patients treated for several months ... ...

    Abstract Background: Cyclosporin A (CyA) may induce acute nephrotoxicity. The question has been raised of the possible long-term unfavorable course of CyA-induced lesions. Advantage was taken of a large cohort of diabetic patients treated for several months using moderate CyA dosage to evaluate the long-term evolution of renal function in such patients.
    Methods: Two hundred and eighty five recently diagnosed type 1 diabetic patients having received CyA for a mean of 19.9 months were monitored for 13 years, in parallel with 100 similar patients treated with insulin alone.
    Results: In the CyA-treated group, a transient increase in creatininemia levels occurred during the first 18 months of treatment associated with a transient increase in renal vascular resistance. Both effects disappeared later on: creatininemia levels then remained normal. Inulin and p-aminohippurate (PAH) clearances remained normal throughout follow-up. Neither permanent renal failure nor progressive deterioration of renal function occurred in either group or in individual patients. A 10 to 12% increase in inulin and PAH clearance was elicited by IV amino acid infusion at 7 to 10 years, a finding consistent with a normal renal functional reserve. Patients with moderate kidney lesions on biopsy at 1 year had normal and stable clearance values at 7 to 13 years. The prevalence of arterial hypertension and retinopathy was lower in the CyA-treated group than in the control group, possibly because of the tighter metabolic control obtained in the CyA group.
    Conclusion: These results suggest that low-dose CyA treatment combined with thorough monitoring does not result in long-term renal dysfunction.
    MeSH term(s) Adult ; Autoimmune Diseases/drug therapy ; Creatinine/blood ; Cyclosporine/administration & dosage ; Cyclosporine/toxicity ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 1/physiopathology ; Female ; Follow-Up Studies ; Glomerular Filtration Rate/drug effects ; Humans ; Hypertension/chemically induced ; Immunosuppressive Agents/therapeutic use ; Immunosuppressive Agents/toxicity ; Inulin/pharmacokinetics ; Kidney/drug effects ; Kidney/physiopathology ; Kidney Diseases/chemically induced ; Kidney Diseases/pathology ; Kidney Function Tests ; Male ; Pregnancy ; Proteinuria/chemically induced ; Time Factors ; Vascular Resistance/drug effects
    Chemical Substances Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D) ; Inulin (9005-80-5) ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2002-11
    Publishing country England
    Document type Clinical Trial ; Controlled Clinical Trial ; Journal Article
    ZDB-ID 1470192-3
    ISSN 1520-7552
    ISSN 1520-7552
    DOI 10.1002/dmrr.325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2119: Show issues Location:
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  10. Article ; Online: Fetal Metabolic Response to Phloridzin-Induced Hypoglycemia in Pregnant Rats

    Freund, Nicole / Kervran, Alain / Assan, Roger / Geloso, Jean-Pierre / Girard, Jean

    Neonatology - Fetal and Neonatal Research

    1980  Volume 38, Issue 5-6, Page(s) 321–327

    Abstract: Phloridzin, an inhibitor of renal sugar transport, produces an important loss of glucose in urine of treated animals. In order to reduce severely the maternal glucose supply to the fetuses in short-term experiments, we have combined phloridzin ... ...

    Abstract Phloridzin, an inhibitor of renal sugar transport, produces an important loss of glucose in urine of treated animals. In order to reduce severely the maternal glucose supply to the fetuses in short-term experiments, we have combined phloridzin administration to pregnant rats with 18 h starvation. Fetuses from starved phloridzin-treated mothers were compared with fetuses from starved mothers. Combined treatment markedly decreases fetal blood glucose concentration (--36%) and fetal liver glycogen stores (--76%). These changes are associated with a decrease in plasma insulin (--25%), a rise in plasma glucagon (+120%) and a marked increase of hepatic PEPCK activity (+400%). It appears from these results that phloridzin treatment for a short duration is able to induce glycogenolysis and the premature appearance of PEPCK in the liver of rat fetuses.
    Keywords Maternal and fetal metabolism ; Liver glycogen ; Insulin ; Glucagon ; Liver PEPCK
    Language English
    Publisher S. Karger AG
    Publishing place Basel
    Publishing country Switzerland
    Document type Article ; Online
    ZDB-ID 2266911-5
    ISSN 1661-7819 ; 1661-7800 ; 1661-7800
    ISSN (online) 1661-7819
    ISSN 1661-7800
    DOI 10.1159/000241382
    Database Karger publisher's database

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    Zs.A 391: Show issues Location:
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