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  1. Article: Laparoscopic combined colorectal and liver resections for primary colorectal cancer with synchronous liver metastases.

    Takorov, Ivelin / Belev, Nikolay / Lukanova, Tsonka / Atanasov, Boiko / Dzharov, Georgi / Djurkov, Ventzeslav / Odisseeva, Evelina / Vladov, Nikola

    Annals of hepato-biliary-pancreatic surgery

    2016  Volume 20, Issue 4, Page(s) 167–172

    Abstract: Backgrounds/aims: Synchronous liver metastases (SLMs) are found in 15-25% of patients at the time of diagnosis with colorectal cancer, which is limited to the liver in 30% of patients. Surgical resection is the most effective and potentially curative ... ...

    Abstract Backgrounds/aims: Synchronous liver metastases (SLMs) are found in 15-25% of patients at the time of diagnosis with colorectal cancer, which is limited to the liver in 30% of patients. Surgical resection is the most effective and potentially curative therapy for metastatic colorectal carcinoma (CRC) of the liver. The comparison of simultaneous resection of primary CRC and synchronous liver metastases with staged resections is the subject of debate with respect to morbidity. Laparoscopic surgery improves postoperative recovery, diminishes postoperative pain, reduces wound infections, shortens hospitalization, and yields superior cosmetic results, without compromising the oncological outcome. The aim of this study is therefore to evaluate our initial experience with simultaneous laparoscopic resection of primary CRC and SLM.
    Methods: Currently, laparoscopic resection of primary CRC is performed in more than 53% of all patients in our surgical department. Twenty-six patients with primary CRC and a clinical diagnosis of SLM underwent combined laparoscopic colorectal and liver surgery. Six of them underwent laparoscopic colorectal resection combined with major laparoscopic liver resection.
    Results: The surgical approaches were total laparoscopic (25 patients) or hybrid technique (1 patients). The incision created for the extraction of the specimen varied between 5 and 8cm. The median operation time was 223 minutes (100 to 415 min.) with a total blood loss of 180 ml (100-300 ml). Postoperative hospital stay was 6.8 days (6-14 days). Postoperative complications were observed in 6 patients (22.2%).
    Conclusions: Simultaneous laparoscopic colorectal and liver resection appears to be safe, feasible, and with satisfying short-term results in selected patients with CRC and SLM.
    Language English
    Publishing date 2016-11-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3012179-6
    ISSN 2508-5859 ; 2508-5778
    ISSN (online) 2508-5859
    ISSN 2508-5778
    DOI 10.14701/ahbps.2016.20.4.167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prospective Observational Study on acute Appendicitis Worldwide (POSAW).

    Sartelli, Massimo / Baiocchi, Gian L / Di Saverio, Salomone / Ferrara, Francesco / Labricciosa, Francesco M / Ansaloni, Luca / Coccolini, Federico / Vijayan, Deepak / Abbas, Ashraf / Abongwa, Hariscine K / Agboola, John / Ahmed, Adamu / Akhmeteli, Lali / Akkapulu, Nezih / Akkucuk, Seckin / Altintoprak, Fatih / Andreiev, Aurelia L / Anyfantakis, Dimitrios / Atanasov, Boiko /
    Bala, Miklosh / Balalis, Dimitrios / Baraket, Oussama / Bellanova, Giovanni / Beltran, Marcelo / Melo, Renato Bessa / Bini, Roberto / Bouliaris, Konstantinos / Brunelli, Daniele / Castillo, Adrian / Catani, Marco / Che Jusoh, Asri / Chichom-Mefire, Alain / Cocorullo, Gianfranco / Coimbra, Raul / Colak, Elif / Costa, Silvia / Das, Koray / Delibegovic, Samir / Demetrashvili, Zaza / Di Carlo, Isidoro / Kiseleva, Nadezda / El Zalabany, Tamer / Faro, Mario / Ferreira, Margarida / Fraga, Gustavo P / Gachabayov, Mahir / Ghnnam, Wagih M / Giménez Maurel, Teresa / Gkiokas, Georgios / Gomes, Carlos A / Griffiths, Ewen / Guner, Ali / Gupta, Sanjay / Hecker, Andreas / Hirano, Elcio S / Hodonou, Adrien / Hutan, Martin / Ioannidis, Orestis / Isik, Arda / Ivakhov, Georgy / Jain, Sumita / Jokubauskas, Mantas / Karamarkovic, Aleksandar / Kauhanen, Saila / Kaushik, Robin / Kavalakat, Alfie / Kenig, Jakub / Khokha, Vladimir / Khor, Desmond / Kim, Dennis / Kim, Jae I / Kong, Victor / Lasithiotakis, Konstantinos / Leão, Pedro / Leon, Miguel / Litvin, Andrey / Lohsiriwat, Varut / López-Tomassetti Fernandez, Eudaldo / Lostoridis, Eftychios / Maciel, James / Major, Piotr / Dimova, Ana / Manatakis, Dimitrios / Marinis, Athanasio / Martinez-Perez, Aleix / Marwah, Sanjay / McFarlane, Michael / Mesina, Cristian / Pędziwiatr, Michał / Michalopoulos, Nickos / Misiakos, Evangelos / Mohamedahmed, Ali / Moldovanu, Radu / Montori, Giulia / Mysore Narayana, Raghuveer / Negoi, Ionut / Nikolopoulos, Ioannis / Novelli, Giuseppe / Novikovs, Viktors / Olaoye, Iyiade / Omari, Abdelkarim / Ordoñez, Carlos A / Ouadii, Mouaqit / Ozkan, Zeynep / Pal, Ajay / Palini, Gian M / Partecke, Lars I / Pata, Francesco / Pereira Júnior, Gerson A / Pintar, Tadeja / Pisarska, Magdalena / Ploneda-Valencia, Cesar F / Pouggouras, Konstantinos / Prabhu, Vinod / Ramakrishnapillai, Padmakumar / Regimbeau, Jean-Marc / Reitz, Marianne / Rios-Cruz, Daniel / Saar, Sten / Sakakushev, Boris / Seretis, Charalampos / Sazhin, Alexander / Shelat, Vishal / Skrovina, Matej / Smirnov, Dmitry / Spyropoulos, Charalampos / Strzałka, Marcin / Talving, Peep / Teixeira Gonsaga, Ricardo A / Theobald, George / Tomadze, Gia / Torba, Myftar / Tranà, Cristian / Ulrych, Jan / Uzunoğlu, Mustafa Y / Vasilescu, Alin / Occhionorelli, Savino / Venara, Aurélien / Vereczkei, Andras / Vettoretto, Nereo / Vlad, Nutu / Walędziak, Maciej / Yilmaz, Tonguç U / Yuan, Kuo-Ching / Yunfeng, Cui / Zilinskas, Justas / Grelpois, Gérard / Catena, Fausto

    World journal of emergency surgery : WJES

    2018  Volume 13, Page(s) 19

    Abstract: Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult ... ...

    Abstract Background: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments.
    Methods: This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016-September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study.
    Results: A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%.
    Conclusions: The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
    MeSH term(s) Acute Disease/therapy ; Adult ; Appendectomy/adverse effects ; Appendectomy/methods ; Appendectomy/standards ; Appendicitis/surgery ; Chi-Square Distribution ; Female ; Hospitalization/statistics & numerical data ; Humans ; Laparoscopy/methods ; Laparoscopy/statistics & numerical data ; Length of Stay/statistics & numerical data ; Logistic Models ; Male ; Prospective Studies ; Tomography, X-Ray Computed/methods ; Treatment Outcome
    Language English
    Publishing date 2018-04-16
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Observational Study
    ISSN 1749-7922
    ISSN (online) 1749-7922
    DOI 10.1186/s13017-018-0179-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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