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  1. Article: Perceived and Real Histopathology Turnaround Time: A Teaching Hospital Experience.

    Atanda, Akinfenwa Taoheed / Yusuf, Ibrahim / Haruna, Muhammad Sanusi

    Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society

    2017  Volume 23, Issue 2, Page(s) 98–101

    Abstract: Background: This study aims to audit analytic turnaround time (TAT) in a histopathology laboratory with a view to assessing the timeliness of its reports, identify causes of delay in its TAT, and compare this with client perception of its performance.!## ...

    Abstract Background: This study aims to audit analytic turnaround time (TAT) in a histopathology laboratory with a view to assessing the timeliness of its reports, identify causes of delay in its TAT, and compare this with client perception of its performance.
    Materials and methods: Records of 1440 batches of specimens processed over a 5-year period in the histopathology laboratory of a teaching hospital were retrieved from archives. From these, median and mean TATs were calculated and causes of delay identified. Questionnaires were also deployed to assess physicians' perception of the laboratory's performance.
    Results: Analytic TAT was 3.6 ± 2 days, with 86.7% of reports being ready within 5 working days. The delays in timeliness of report generation were due mainly to residency training-related factors; tissue processing-related factors, and inadequate clinical information among others. Client perception of TAT rated the laboratory below average by 18.4%; average by 57.5%; good by 20.7%, and excellent in its performance by 3.4% of respondents.
    Conclusion: Even though physicians perceived the laboratory's TAT to be just average, its analytic TAT for reports is within acceptable international standards but with room for improvement in its performance.
    Language English
    Publishing date 2017-11-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2641743-1
    ISSN 2278-7100 ; 1117-6806
    ISSN (online) 2278-7100
    ISSN 1117-6806
    DOI 10.4103/njs.NJS_4_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Incidence and risk factors of cervical dysplasia among human immune deficiency virus positive and human immune deficiency virus negative women at Aminu Kano Teaching Hospital

    Zakari Muhammad / Iman Haruna Usman / Zainab Ahmed Datti / Attah Rapheal Avidime / Shuaibu Adavuruku Danjuma / Atanda Akinfenwa Taoheed / Aisha Abdullahi Suleiman

    Sahel Medical Journal, Vol 20, Iss 4, Pp 160-

    2017  Volume 167

    Abstract: Background: HIV infection is a risk factor for cervical cancer and both diseases are prevalent in Nigeria. HIV positive women are at greater risk of cervical dysplasia than HIV negative women which may be as a result of immunosupression, hence adding ... ...

    Abstract >Background: HIV infection is a risk factor for cervical cancer and both diseases are prevalent in Nigeria. HIV positive women are at greater risk of cervical dysplasia than HIV negative women which may be as a result of immunosupression, hence adding more burdens to their already worsening health condition. It has become relevant to screen these women early and refer for appropriate and effective therapeutic intervention.Objective: To compare the incidence and risk factors of cervical dysplasia among HIV positive and HIV negative women at Aminu Kano Teaching Hospital, Kano.Methods: This was a comparative cross sectional studyl, which involved HIV positive women attending HIV clinic and HIV negative women attending the gynecological clinic at Aminu Kano Teaching Hospital. A cohort of 150 consenting HIV- positive women not on HAART and 150 HIV- negative women, selected by systematic random sampling were sent for Pap smear examination. On the same day blood samples were taken from antecubital vein and sent for both CD4 count and viral load among the HIV positive group. A pretested questionnaire was administered to the women of both groups on same day to determine the presence or absence of risk factors of cervical dysplasia in them. The results obtained were recorded using proforma and analyses of risk factors of cervical dysplasia was done using Chi square test and Fisher exact test to compare variables between those with normal and abnormal smears and student t test to determine the relationship of lesions with CD4count and viral load among the HIV positive women.Results: The incidence of cervical dysplasia among HIV- positive women was 49 (32.7%) and was significantly higher than 12(8%) found among the HIV- negative. Age ≥ 35years and parity ≥5, early coitarche, multiple sexual partners, low-socioeconomic status, cigarette smoking did confer some risk of dysplasia however. This study also showed that among the HIV positive group, CD4 count was inversely associated with risk of cervical dysplasia and women ...
    Keywords Aminu Kano Teaching Hospital-Kano ; cervical dysplasia ; human immune deficiency virus-positive women ; incidence ; risk factors ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Wilms' tumour in African children: Can an institutional approach improve outcome?

    Anyanwu, Lofty-John Chukwuemeka / Anyanwa, Lofty-John Chukwuemeka / Atanda, Akinfenwa Taoheed / Atanda, Jareenat Oladoyin

    African journal of paediatric surgery : AJPS

    2015  Volume 12, Issue 1, Page(s) 7–11

    Abstract: Background: The poor outcome for patients with Wilms' tumour (WT) in developing countries has been predicated on late presentation, poverty and low rate of chemotherapeutic access. This study aims to evaluate the effects of an institutionalised approach ...

    Abstract Background: The poor outcome for patients with Wilms' tumour (WT) in developing countries has been predicated on late presentation, poverty and low rate of chemotherapeutic access. This study aims to evaluate the effects of an institutionalised approach to improving outcome for patients managed in a tertiary hospital in Nigeria.
    Materials and methods: Oncology records of children diagnosed with WT between 2009 and 2013 were analysed for therapy completion and other prognostic parameters. Ensuing data were then compared with those from other centres in Africa.
    Results: Compared with results from some local and African studies, the therapy completion rate was higher (60%) with a survival rate among this group being between 1 and 4 years. No patient was lost to follow-up because of unavailability or unaffordability of cytotoxic agents.
    Conclusion: This study shows that an institutionalised approach can help to improve access to anti-cancer drugs, reduce the rate of loss to follow-up and thus improve outcome. There is however need to improve on patient-doctor communication, form support groups and establish a WT registry.
    MeSH term(s) Arabidopsis Proteins ; Biopsy ; Child, Preschool ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Incidence ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/therapy ; Lost to Follow-Up ; Male ; Neoplasm Staging ; Nigeria/epidemiology ; Prognosis ; Retrospective Studies ; Survival Rate/trends ; Transcription Factors ; Treatment Outcome ; Wilms Tumor/diagnosis ; Wilms Tumor/epidemiology ; Wilms Tumor/therapy
    Chemical Substances Arabidopsis Proteins ; TOC1 protein, Arabidopsis ; Transcription Factors
    Language English
    Publishing date 2015-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2392865-7
    ISSN 0974-5998 ; 0189-6725
    ISSN (online) 0974-5998
    ISSN 0189-6725
    DOI 10.4103/0189-6725.150926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Wilms' tumour: Determinants of prognosis in an African setting.

    Atanda, Akinfenwa Taoheed / Anyanwu, Lofty-John Chuhwuemeka / Atanda, Oladoyin Jareenat / Mohammad, Aminu Mohammad / Abdullahi, Lawal Barau / Farinyaro, Aliyu Umar

    African journal of paediatric surgery : AJPS

    2015  Volume 12, Issue 3, Page(s) 171–176

    Abstract: Background: The few studies available in the literature on Wilms' tumour (WT) from sub-Saharan Africa have reported a dismal outcome for children with the tumour. This study evaluated the risk factors that have been correlated with outcome in the ... ...

    Abstract Background: The few studies available in the literature on Wilms' tumour (WT) from sub-Saharan Africa have reported a dismal outcome for children with the tumour. This study evaluated the risk factors that have been correlated with outcome in the literature and compare these with outcome among our patients.
    Materials and methods: Cases of histologically confirmed WT between 2009 and 2013 in a tertiary hospital in Northwestern Nigeria were evaluated for gender, age, laterality, symptoms, duration before presentation, stage at presentation, histologic subtype and p53 mutation. These were then correlated with outcome.
    Results: Totally, 30 cases of WT were diagnosed with mean age of 4.8 ± 1.9 years; and male:female ratio of 2:1. No statistically significant relationship with outcome was found for gender (P = 0.138) or histologic subtype (P = 0.671). The most significant variables which positively influenced the outcome were presentation at earlier stages (P = 0.007) and completion of therapy (P = 0.0007). p53 mutation was seen in 3 (16.7%) of 18 cases and was not associated with a poor outcome (P = 0.089). However, 2 of the 3 cases presented in Stage IV and none of them survived the 1 st year.
    Conclusion: This study shows that even though p53 mutation was associated with a more aggressive phenotype, the most significant determinants of a good outcome among patients in a developing country like ours is non-blastemal dominant histologic subtype, early stage at presentation and completion of therapy.
    MeSH term(s) Child, Preschool ; Female ; Humans ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/surgery ; Male ; Morbidity/trends ; Nephrectomy/methods ; Nigeria/epidemiology ; Prognosis ; Retrospective Studies ; Risk Factors ; Survival Rate/trends ; Treatment Outcome ; Wilms Tumor/diagnosis ; Wilms Tumor/epidemiology ; Wilms Tumor/surgery
    Language English
    Publishing date 2015-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 2392865-7
    ISSN 0974-5998 ; 0189-6725
    ISSN (online) 0974-5998
    ISSN 0189-6725
    DOI 10.4103/0189-6725.170185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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