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  1. Article ; Online: G20 leaders must answer to COVID-19.

    Atkinson, Caroline

    Science (New York, N.Y.)

    2020  Volume 368, Issue 6487, Page(s) 111

    MeSH term(s) Betacoronavirus/immunology ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Economics ; Global Health ; Humans ; International Cooperation ; Leadership ; Pandemics/prevention & control ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Viral Vaccines
    Chemical Substances COVID-19 vaccine ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abc1025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: G20 leaders must answer to COVID-19

    Atkinson, Caroline

    Science

    2020  Volume 368, Issue 6487, Page(s) 111–111

    Keywords Multidisciplinary ; covid19
    Language English
    Publisher American Association for the Advancement of Science (AAAS)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abc1025
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Quantification of vincristine and tariquidar by liquid chromatography-tandem mass spectrometry in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic applications.

    Rosser, Sebastian P A / Atkinson, Caroline / Nath, Christa E / Fletcher, Jamie I

    Journal of separation science

    2022  Volume 45, Issue 14, Page(s) 2508–2519

    Abstract: A liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of vincristine and tariquidar in 10 μL of mouse whole blood using volumetric absorptive microsampling devices. Samples were extracted ... ...

    Abstract A liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of vincristine and tariquidar in 10 μL of mouse whole blood using volumetric absorptive microsampling devices. Samples were extracted from the devices and quantified against calibrators prepared in a human blood plasma matrix. Separation of vincristine and tariquidar was achieved using a Shimpack XR ODS III C18 stationary phase and H
    MeSH term(s) Animals ; Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid/methods ; Humans ; Mice ; Quinolines ; Reproducibility of Results ; Tandem Mass Spectrometry/methods ; Vincristine
    Chemical Substances Quinolines ; Vincristine (5J49Q6B70F) ; tariquidar (J58862DTVD)
    Language English
    Publishing date 2022-05-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2047990-6
    ISSN 1615-9314 ; 1615-9306
    ISSN (online) 1615-9314
    ISSN 1615-9306
    DOI 10.1002/jssc.202101013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Quantification of vincristine and tariquidar by liquid chromatography‐tandem mass spectrometry in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic applications

    Rosser, Sebastian P. A. / Atkinson, Caroline / Nath, Christa E. / Fletcher, Jamie I.

    Journal of separation science. 2022 July, v. 45, no. 14

    2022  

    Abstract: A liquid chromatography‐tandem mass spectrometry method was developed and validated for the simultaneous quantification of vincristine and tariquidar in 10 μL of mouse whole blood using volumetric absorptive microsampling devices. Samples were extracted ... ...

    Abstract A liquid chromatography‐tandem mass spectrometry method was developed and validated for the simultaneous quantification of vincristine and tariquidar in 10 μL of mouse whole blood using volumetric absorptive microsampling devices. Samples were extracted from the devices and quantified against calibrators prepared in a human blood plasma matrix. Separation of vincristine and tariquidar was achieved using a Shimpack XR ODS III C18 stationary phase and H₂O and methanol mobile phase solvents containing 0.1% formic acid, running a gradient elution at a flow rate of 0.2 mL/min over 6.0 min. The method was linear up to 1200 ng/mL (R² > 0.99 for both analytes), with calibrator accuracy within ± 15% of the nominal concentrations and analyte coefficient of variance <15% for both vincristine and tariquidar. Pharmacokinetic assessment of both analytes was successfully applied in mice as both single‐agent therapy and combination therapy over a 24‐h period, and a 2.3‐fold increase in vincristine drug exposure was observed in combination with tariquidar. This study validates the use of this approach for longitudinal analysis of drug exposure in animal studies.
    Keywords blood plasma ; chemical species ; formic acid ; humans ; liquid chromatography ; longitudinal studies ; methanol ; mice ; pharmacokinetics ; separation ; tandem mass spectrometry ; therapeutics ; variance ; vincristine
    Language English
    Dates of publication 2022-07
    Size p. 2508-2519.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2047990-6
    ISSN 1615-9314 ; 1615-9306
    ISSN (online) 1615-9314
    ISSN 1615-9306
    DOI 10.1002/jssc.202101013
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Mitigating Contemporary Trauma Impacts Using Ancient Applications.

    Morris, Gavin / Groom, Rachel / Schuberg, Emma / Atkinson, Judy / Atkinson, Caroline / Ungunmerr-Baumann, Miriam-Rose

    Frontiers in psychology

    2022  Volume 13, Page(s) 645397

    Abstract: The COVID-19 pandemic represents the most significant global challenge in a generation. Based on extant data from previous pandemics, demographic, occupational, and psychological factors have been linked to distress and for some vulnerable members of ... ...

    Abstract The COVID-19 pandemic represents the most significant global challenge in a generation. Based on extant data from previous pandemics, demographic, occupational, and psychological factors have been linked to distress and for some vulnerable members of society. COVID-19 has added to the layers of grief and distress of existing trauma. Evidence-based frameworks exist to guide our individual and collective response to reduce the trauma associated with the experience of a pandemic. Pandemic and post-pandemic measures to ameliorate impacts require a multi-disciplined approach, central to which is community connectedness, resilience, and access to support. We advocate for the acceptance and broader application of Dadirri, a healing practice held by the Ngan'gikurunggurr and Ngen'giwumirri Aboriginal people of the Daly River region in the Northern Territory, Australia. This modality engages therapeutic phases that are comparable with other practiced trauma therapies. The demonstrated therapeutic outcomes from Dadirri can be attained through an individualistic or in a relational engagement context. This practice is accessible to all ages, is non-specific to gender and is suitable for people constrained in their mobility or limited by resources, pertinent in pandemic affected settings.
    Language English
    Publishing date 2022-08-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.645397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mouse models of high-risk neuroblastoma.

    Kamili, Alvin / Atkinson, Caroline / Trahair, Toby N / Fletcher, Jamie I

    Cancer metastasis reviews

    2020  Volume 39, Issue 1, Page(s) 261–274

    Abstract: Informative and realistic mouse models of high-risk neuroblastoma are central to understanding mechanisms of tumour initiation, progression, and metastasis. They also play vital roles in validating tumour drivers and drug targets, as platforms for ... ...

    Abstract Informative and realistic mouse models of high-risk neuroblastoma are central to understanding mechanisms of tumour initiation, progression, and metastasis. They also play vital roles in validating tumour drivers and drug targets, as platforms for assessment of new therapies and in the generation of drug sensitivity data that can inform treatment decisions for individual patients. This review will describe genetically engineered mouse models of specific subsets of high-risk neuroblastoma, the development of patient-derived xenograft models that more broadly represent the diversity and heterogeneity of the disease, and models of primary and metastatic disease. We discuss the research applications, advantages, and limitations of each model type, the importance of model repositories and data standards for supporting reproducible, high-quality research, and potential future directions for neuroblastoma mouse models.
    MeSH term(s) Animals ; Disease Models, Animal ; Humans ; Mice ; Neuroblastoma/pathology ; Neuroblastoma/therapy ; Risk Factors ; Xenograft Model Antitumor Assays/methods
    Language English
    Publishing date 2020-01-23
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 604857-2
    ISSN 1573-7233 ; 0167-7659
    ISSN (online) 1573-7233
    ISSN 0167-7659
    DOI 10.1007/s10555-020-09855-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Colombia: 2007 Article IV consultation

    Atkinson, Caroline

    staff report, staff supplement and public information notice on the Executive Board discussion

    (IMF country report ; 08.31)

    2008  

    Author's details [approved by Caroline Atkinson ...]
    Series title IMF country report ; 08.31
    Language English
    Size 40, 8, 5 S., graph. Darst.
    Publisher Internat. Monetary Fund
    Publishing place Washington, DC
    Document type Book
    Database ECONomics Information System

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  8. Book: Haiti

    Atkinson, Caroline

    third review under the three-year arrangement under the poverty reduction and growth facility, requests for augmentation of access and waiver of nonobservance of performance criteria and request for additional interim assistance under the enhanced initiative for heavily indebted poor countries ; staff report, press release on the Executive Board discussion and statement by the Executive Director for Haiti

    (IMF country report ; 08.223)

    2008  

    Author's details [approved by Caroline Atkinson ...]
    Series title IMF country report ; 08.223
    Language English
    Size 43, [16] S., graph. Darst.
    Publisher Internat. Monetary Fund
    Publishing place Washington, DC
    Document type Book
    Database ECONomics Information System

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  9. Book: Haiti: second review under the three-year arrangement under the poverty reduction and growth facility and request for waiver of nonobservance of performance criteria

    Atkinson, Caroline

    staff report, staff statement on the Executive Board discussion and statement by the Executive Director for Haiti

    (IMF country report ; 08.117)

    2008  

    Author's details [approved by Caroline Atkinson ...]
    Series title IMF country report ; 08.117
    Language English
    Size 51, [38] S., graph. Darst.
    Publisher Internat. Monetary Fund
    Publishing place Washington, DC
    Document type Book
    Database ECONomics Information System

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