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  1. Article ; Online: Standing Surgical Management of Splint Bone Fractures in 13 Horses: A Comparison to Management Under General Anaesthesia.

    Auffret, Vincent / Bonilla, Alvaro G

    Veterinary and comparative orthopaedics and traumatology : V.C.O.T

    2023  Volume 36, Issue 3, Page(s) 148–156

    Abstract: Objective:  The aim of this article was to describe the technique and outcomes of standing surgical management of splint bone fractures and to compare outcome variables and hospitalization cost to a group with similar fractures treated under general ... ...

    Abstract Objective:  The aim of this article was to describe the technique and outcomes of standing surgical management of splint bone fractures and to compare outcome variables and hospitalization cost to a group with similar fractures treated under general anaesthesia.
    Study design:  It is a single-institution retrospective study. Surgical technique, surgical time, hospitalization cost and complications were retrieved from the medical records of horses treated surgically for splint bone fractures (2008-2020). Owner telephone follow-up provided data about athletic outcome, client satisfaction and cosmetic appearance.
    Results:  Forty-nine horses (13 standing, 36 under general anaesthesia) with 57 fractures (18 contaminated and 39 non-contaminated) were included. Seven fractures were in the proximal third (4 standing, 3 under general anaesthesia), 18 in the middle third (5 standing, 13 under general anaesthesia) and 30 were distal (4 standing, 26 under general anaesthesia). No significant difference between groups in surgical time was found (p= 0.8). Average total cost was 522 CAN$ lower for the standing group for non-contaminated fractures (p= 0.02). Three horses of the general anaesthesia group demonstrated postoperative colic signs and one case of the standing group was re-operated due to sequestration. Based on follow-up information (range: 3.8-151.2 months), no significant differences in cosmetic and athletic outcomes were found between groups.
    Conclusion:  Surgical management of splint bone fractures in the standing horse is a valuable alternative for horses selected based on behaviour. When compared to general anaesthesia, standing management of splint bone fractures did not alter the surgical time or outcome variables and avoided general anaesthesia-associated risks.
    MeSH term(s) Horses ; Animals ; Retrospective Studies ; Splints ; Fractures, Bone/surgery ; Fractures, Bone/veterinary ; Metacarpal Bones ; Anesthesia, General/veterinary ; Horse Diseases/surgery
    Language English
    Publishing date 2023-02-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 286750-3
    ISSN 2567-6911 ; 0932-0814
    ISSN (online) 2567-6911
    ISSN 0932-0814
    DOI 10.1055/s-0043-1761241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Right Ventricular-Pulmonary Artery Coupling After Transcatheter Aortic Valve Replacement: Closer to Optimal Prognosis Assessment?

    Auffret, Vincent / Leurent, Guillaume

    JACC. Cardiovascular interventions

    2023  Volume 16, Issue 13, Page(s) 1622–1625

    MeSH term(s) Humans ; Pulmonary Artery/diagnostic imaging ; Transcatheter Aortic Valve Replacement/adverse effects ; Treatment Outcome ; Prognosis
    Language English
    Publishing date 2023-04-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.05.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Residual volume of extruded disc material and residual spinal cord compression measured on postoperative MRI do not predict neurological outcomes in dogs following decompressive surgery for thoracolumbar intervertebral disc extrusion.

    Auffret, Vincent / Castel, Aude / Juette, Tristan / Finck, Cyrielle

    Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

    2024  Volume 65, Issue 2, Page(s) 76–86

    Abstract: Published studies on the validity of using quantitative MRI measures of pre- and postoperative spinal cord (SC) compression as prognostic indicators for dogs undergoing surgery for intervertebral disc extrusion (IVDE) are currently limited. The aim of ... ...

    Abstract Published studies on the validity of using quantitative MRI measures of pre- and postoperative spinal cord (SC) compression as prognostic indicators for dogs undergoing surgery for intervertebral disc extrusion (IVDE) are currently limited. The aim of this retrospective analytical study was to describe the volume of postoperative residual extradural material (VREM) and the ratio of the cross-sectional area (CSA) of maximum SC compression to the CSA of SC in a compression-free intervertebral space as MRI measures of preoperative and postoperative compression (residual spinal cord compression, RSCC), and to compare these measures between the neurological outcome in a group of dogs. Inclusion criteria were dogs that underwent surgery for thoracolumbar IVDE, were imaged pre- and immediately postoperatively by MRI, and had a neurological follow-up examination 2 to 5 weeks postoperatively. Two blinded observers independently performed measurements in pre- and postoperative MRI studies. Dogs were classified into positive outcome (PO) and negative outcome (NO) groups based on follow-up neurologic examination scores. Seventeen dogs were included (12 PO, 5 NO). Interobserver agreement for MRI measurements was good to excellent (ICCs: 0.76-0.97). The prevalence of residual extradural material in postoperative MRI studies was 100%. No significant differences in mean preoperative SC compression, mean RSCC, mean SC decompression, or VREM were found between outcome groups (P = .25; P = .28; P = .91, P = .98). In conclusion, neither postoperative VREM nor RSCC could predict successful neurological outcomes.
    MeSH term(s) Dogs ; Animals ; Spinal Cord Compression/diagnostic imaging ; Spinal Cord Compression/surgery ; Spinal Cord Compression/veterinary ; Retrospective Studies ; Residual Volume ; Dog Diseases/diagnostic imaging ; Dog Diseases/surgery ; Intervertebral Disc Displacement/diagnostic imaging ; Intervertebral Disc Displacement/surgery ; Intervertebral Disc Displacement/veterinary ; Magnetic Resonance Imaging/veterinary ; Intervertebral Disc
    Language English
    Publishing date 2024-01-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2142058-0
    ISSN 1740-8261 ; 1058-8183
    ISSN (online) 1740-8261
    ISSN 1058-8183
    DOI 10.1111/vru.13325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Standing Surgical Management of Splint Bone Fractures in 13 Horses: A Comparison to Management Under General Anaesthesia

    Auffret, Vincent / Bonilla, Alvaro G.

    Veterinary and Comparative Orthopaedics and Traumatology

    2023  Volume 36, Issue 03, Page(s) 148–156

    Abstract: Objective: The aim of this article was to describe the technique and outcomes of standing surgical management of splint bone fractures and to compare outcome variables and hospitalization cost to a group with similar fractures treated under general ... ...

    Abstract Objective: The aim of this article was to describe the technique and outcomes of standing surgical management of splint bone fractures and to compare outcome variables and hospitalization cost to a group with similar fractures treated under general anaesthesia.
    Study Design: It is a single-institution retrospective study. Surgical technique, surgical time, hospitalization cost and complications were retrieved from the medical records of horses treated surgically for splint bone fractures (2008–2020). Owner telephone follow-up provided data about athletic outcome, client satisfaction and cosmetic appearance.
    Results: Forty-nine horses (13 standing, 36 under general anaesthesia) with 57 fractures (18 contaminated and 39 non-contaminated) were included. Seven fractures were in the proximal third (4 standing, 3 under general anaesthesia), 18 in the middle third (5 standing, 13 under general anaesthesia) and 30 were distal (4 standing, 26 under general anaesthesia). No significant difference between groups in surgical time was found (p= 0.8). Average total cost was 522 CAN$ lower for the standing group for non-contaminated fractures (p= 0.02). Three horses of the general anaesthesia group demonstrated postoperative colic signs and one case of the standing group was re-operated due to sequestration. Based on follow-up information (range: 3.8-151.2 months), no significant differences in cosmetic and athletic outcomes were found between groups.
    Conclusion: Surgical management of splint bone fractures in the standing horse is a valuable alternative for horses selected based on behaviour. When compared to general anaesthesia, standing management of splint bone fractures did not alter the surgical time or outcome variables and avoided general anaesthesia-associated risks.
    Keywords splint bone fractures ; standing surgery ; horse ; metacarpal bone ; metatarsal bone
    Language English
    Publishing date 2023-02-09
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 286750-3
    ISSN 2567-6911 ; 0932-0814
    ISSN (online) 2567-6911
    ISSN 0932-0814
    DOI 10.1055/s-0043-1761241
    Database Thieme publisher's database

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  5. Article: Unmet Needs in TAVR: Conduction Disturbances and Management of Coronary Artery Disease.

    Auffret, Vincent / Ridard, Carine / Salerno, Nadia / Sorrentino, Sabato

    Journal of clinical medicine

    2022  Volume 11, Issue 21

    Abstract: Over the past two decades, transcatheter aortic valve replacement (TAVR) swiftly evolved from a disrupting technology towards mainstream therapy in the field of severe symptomatic aortic stenosis. A series of randomized evaluations established its role ... ...

    Abstract Over the past two decades, transcatheter aortic valve replacement (TAVR) swiftly evolved from a disrupting technology towards mainstream therapy in the field of severe symptomatic aortic stenosis. A series of randomized evaluations established its role in treating severe aortic stenosis patients across all surgical risk categories, paving the way for an extension of its indications to younger low-risk patients with a longer life expectancy. Therefore, managing comorbidities and limiting procedural complications, which may affect long-term outcomes, is of paramount importance. Among those, new-onset conduction disturbances and concomitant coronary artery disease remain two of the most debated issues. In the present review, we will discuss the incidence, prognostic impact, and unmet needs of patients with post-TAVR new-onset conduction disturbances and the ongoing challenges posed by the management of concomitant coronary artery disease.
    Language English
    Publishing date 2022-10-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11216256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Right Ventricular-Pulmonary Artery Coupling: A Simple Marker to Guide Complex Clinical Decisions?

    Leurent, Guillaume / Auffret, Vincent / Donal, Erwan

    JACC. Cardiovascular interventions

    2022  Volume 15, Issue 18, Page(s) 1834–1836

    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Heart Valve Prosthesis Implantation ; Humans ; Pulmonary Artery/diagnostic imaging ; Risk Factors ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
    Language English
    Publishing date 2022-08-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2022.08.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antithrombotic After TAVR: No Treatment, No Problem?

    Auffret, Vincent / Guedeney, Paul / Leurent, Guillaume / Didier, Romain

    JACC. Cardiovascular interventions

    2022  Volume 16, Issue 1, Page(s) 92–93

    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Fibrinolytic Agents/adverse effects ; Treatment Outcome ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Platelet Aggregation Inhibitors ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Risk Factors
    Chemical Substances Fibrinolytic Agents ; Platelet Aggregation Inhibitors
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2022.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Association of Arterial Blood pH at Cannulation With 1 Year Survival Among Veno-Arterial Extracorporeal Membrane Oxygenation Recipients: The Three Seven Rule.

    Dib, Nabil / Belaroussi, Yaniss / Mansour, Alexandre / Anselmi, Amedeo / Auffret, Vincent / Nesseler, Nicolas / Flécher, Erwan

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2023  Volume 69, Issue 7, Page(s) e287–e292

    Abstract: We aimed to describe the clinical outcomes of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) therapy in our institution considering clinical context and pH at cannulation. All patients treated by VA-ECMO during the 2005-2020 period with 1 ... ...

    Abstract We aimed to describe the clinical outcomes of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) therapy in our institution considering clinical context and pH at cannulation. All patients treated by VA-ECMO during the 2005-2020 period with 1 year complete follow-up were included. Our cohort was divided in three groups according to the pH level at cannulation: pH <7 (group 1), pH 7-7.2 (group 2), and pH>7.2 (group 3). Survival was analyzed using Kaplan-Meier method. Association between pH group and survival was estimated using a Cox model. A total of 572 patients were included: 60 patients in group 1, 115 in group 2, and 397 in group 3. Refractory cardiogenic shock (36%) was the main indication. One year survival rates were 13%, 36%, and 43% in groups 1, 2, and 3, respectively ( p < 0.001). Death mainly occurred within the first month. The strong correlation between pH and lactates led to propose a simple "three seven rule": pH <7 and lactate >7 was associated with <7% survival. Veno-arterial extracorporeal membrane oxygenation should be considered with caution in patients with pH <7. Lactates and pH might be important parameters to elaborate a new score to predict survival in this population. The "three seven rule" can be very relevant when facing emergency situations.
    MeSH term(s) Humans ; Extracorporeal Membrane Oxygenation/adverse effects ; Shock, Cardiogenic ; Catheterization/adverse effects ; Hydrogen-Ion Concentration ; Retrospective Studies
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Echocardiographic estimation of pulmonary pressure in patients with severe tricuspid regurgitation.

    Lemarchand, Léo / Auffret, Vincent / Le Breton, Hervé / Bedossa, Marc / Boulmier, Dominique / Galli, Elena / Donal, Erwan / Leurent, Guillaume

    Heart (British Cardiac Society)

    2024  Volume 110, Issue 5, Page(s) 366–372

    Abstract: Objectives: The estimation of systolic pulmonary artery pressure (sPAP) by transthoracic echocardiography (TTE) is challenging in patients with severe tricuspid regurgitation (TR). The study aimed to determine the reliability of the assessment of sPAP ... ...

    Abstract Objectives: The estimation of systolic pulmonary artery pressure (sPAP) by transthoracic echocardiography (TTE) is challenging in patients with severe tricuspid regurgitation (TR). The study aimed to determine the reliability of the assessment of sPAP by TTE in this population.
    Methods: This study was a single-centre analysis of consecutive patients at the University Hospital of Rennes with right heart catheterisation and TTE, performed with a maximum delay of 48 hours. Lin's concordance coefficient (LCC) and Bland-Altman analysis were used to compare the values.
    Results: After applying the exclusion criteria, 236 patients were included in the analysis (age 71±11.5 years old; male 56%). The two principal indications were TR (34.3%) and mitral regurgitation (32.2%). The correlation between the two procedures was good in the total population (LCC=0.80; 95% limits of agreement (LOA): 0.74, 0.84), but weaker in the 78 patients (33%) with severe TR (LCC=0.67; 95% LOA: 0.49, 0.80), with a propensity to an underestimation by TTE. An elevated right atrial pressure (RAP) was associated with an underestimation by TTE of about 8 mmHg. The presence of a 'V-wave cut-off' sign on continuous-wave Doppler (OR=3.74; 95% CI 1.48, 9.30; p<0.01), found exclusively in patients with severe TR, was an independent predictor of sPAP misestimation by TTE.
    Conclusion: The reliability of the estimation of sPAP in patients with severe TR could be altered by high RAP which cannot be estimated with current thresholds.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Aged, 80 and over ; Tricuspid Valve Insufficiency/diagnostic imaging ; Reproducibility of Results ; Pulmonary Artery/diagnostic imaging ; Echocardiography/methods ; Cardiac Catheterization/methods
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Bidirectional Restriction of the Mitral Valve Due to an Aberrant Atrial Chordae in an Ischemic Cardiomyopathy.

    Leurent, Guillaume / Donal, Erwan / Auffret, Vincent

    JACC. Cardiovascular interventions

    2021  Volume 15, Issue 1, Page(s) e11–e12

    MeSH term(s) Cardiac Catheterization ; Cardiomyopathies/diagnostic imaging ; Cardiomyopathies/etiology ; Heart Valve Prosthesis Implantation ; Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/etiology ; Mitral Valve Insufficiency/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2021.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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