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  1. Book ; Thesis: Emotional and non-emotional interference in major depressive disorder

    Augustin, Marc

    2015  

    Author's details vorgelegt von Marc Augustin
    Language English
    Size 87 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 2015
    HBZ-ID HT018615481
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2015 D 913 order for loan Magazin

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  2. Article: Ärztliche Gesprächsführung bei Impfskepsis. Guidance for Doctors to Communicate with Vaccine-hesitant Patients

    Augustin, Marc

    Zeitschrift für Allgemeinmedizin

    2021  Volume 97, Issue 11, Page(s) 437

    Language German
    Document type Article
    ZDB-ID 522031-2
    ISSN 1433-6251 ; 0937-6801
    Database Current Contents Medicine

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  3. Article: Antipsychotika im klinischen Einsatz

    Augustin, Marc

    Der Klinikarzt

    2020  Volume 49, Issue 04, Page(s) 130–136

    Abstract: Klinisch tätige Ärztinnen und Ärzte begegnen häufig Patienten, die bereits mit Antipsychotika behandelt werden oder die Erkrankungen wie beispielsweise ein Delir aufweisen, bei denen eine Behandlung mit Antipsychotika erwogen werden kann. Der Artikel ... ...

    Abstract Klinisch tätige Ärztinnen und Ärzte begegnen häufig Patienten, die bereits mit Antipsychotika behandelt werden oder die Erkrankungen wie beispielsweise ein Delir aufweisen, bei denen eine Behandlung mit Antipsychotika erwogen werden kann. Der Artikel gibt einen Überblick über Indikationen, unerwünschte Wirkungen und potenzielle Wechselwirkungen beim Einsatz von Antipsychotika. Besonderes Augenmerk wird auf internistisch relevante unerwünschte Wirkungen gelegt wie thromboembolische Ereignisse, Pneumonie, Agranulozytose und metabolisches Syndrom. Zudem werden bekannte Wechselwirkungen zwischen Antipsychotika und anderen Medikamenten erläutert, die für den klinischen Alltag besondere Relevanz aufweisen. In bestimmten Situationen erfordern diese pharmakokinetischen Wechselwirkungen eine Änderung der Dosis oder den Einsatz von Therapeutischem Drug Monitoring (TDM) zur Bestimmung des Medikamentenspiegels, um die individuell optimale Behandlung zu gewährleisten.
    Language German
    Publishing date 2020-04-01
    Publisher © Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2106610-3
    ISSN 1439-3859 ; 0341-2350
    ISSN (online) 1439-3859
    ISSN 0341-2350
    DOI 10.1055/a-1110-5931
    Database Thieme publisher's database

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  4. Book ; Online ; Thesis: Influence of workers councils on employee engagement – An Action-Research approach to influence employee engagement through workers council initiatives

    Augustin, Marc [Verfasser]

    2020  

    Author's details Marc Augustin
    Keywords Wirtschaft ; Economics
    Subject code sg330
    Language English
    Publisher Marc Augustin
    Publishing place Beckingen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article ; Online: How to learn effectively in medical school: test yourself, learn actively, and repeat in intervals.

    Augustin, Marc

    The Yale journal of biology and medicine

    2014  Volume 87, Issue 2, Page(s) 207–212

    Abstract: Students in medical school often feel overwhelmed by the excessive amount of factual knowledge they are obliged to learn. Although a large body of research on effective learning methods is published, scientifically based learning strategies are not a ... ...

    Abstract Students in medical school often feel overwhelmed by the excessive amount of factual knowledge they are obliged to learn. Although a large body of research on effective learning methods is published, scientifically based learning strategies are not a standard part of the curriculum in medical school. Students are largely unaware of how to learn successfully and improve memory. This review outlines three fundamental methods that benefit learning: the testing effect, active recall, and spaced repetition. The review summarizes practical learning strategies to learn effectively and optimize long-term retention of factual knowledge.
    MeSH term(s) Education, Medical ; Educational Measurement ; Humans ; Learning/physiology ; Mental Recall ; Schools, Medical ; Students, Medical/psychology
    Language English
    Publishing date 2014-06-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 200515-3
    ISSN 1551-4056 ; 0044-0086
    ISSN (online) 1551-4056
    ISSN 0044-0086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Lithium Is Likely to Persist in the Brain: Clinical Implications for Electroconvulsive Therapy.

    Augustin, Marc / Karakavuz, Rahsan / Riester, Luise / Grözinger, Michael

    The journal of ECT

    2021  Volume 37, Issue 1, Page(s) 67–70

    Abstract: Abstract: Electroconvulsive therapy and concomitant lithium therapy remain a matter of debate because of increased rates of adverse events. Current recommendations include monitoring lithium levels and reducing lithium to minimally effective dose. We ... ...

    Abstract Abstract: Electroconvulsive therapy and concomitant lithium therapy remain a matter of debate because of increased rates of adverse events. Current recommendations include monitoring lithium levels and reducing lithium to minimally effective dose. We present a report on protracted effects of lithium intoxication as electroconvulsive therapy 8 days after intoxication and under normal lithium serum levels resulted in a prolonged seizure. Electroencephalogram recordings before stimulation showed electroencephalogram correlates of subsiding lithium intoxication most likely due to protracted lithium influx and efflux of the central nervous system.
    MeSH term(s) Aged ; Brain/metabolism ; Depression/drug therapy ; Drug Therapy, Combination ; Electroconvulsive Therapy ; Electroencephalography ; Female ; Heart Failure/therapy ; Heart-Assist Devices ; Humans ; Lithium Carbonate/adverse effects ; Lithium Carbonate/pharmacokinetics
    Chemical Substances Lithium Carbonate (2BMD2GNA4V)
    Language English
    Publishing date 2021-02-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1426385-3
    ISSN 1533-4112 ; 1095-0680
    ISSN (online) 1533-4112
    ISSN 1095-0680
    DOI 10.1097/YCT.0000000000000719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Sind Wirkfaktoren der Psychotherapie auch für die psychosoziale Beratung relevant? Eine Befragung in Tagesstätten für Menschen mit einer psychischen Erkrankung

    Sprandel, M. Isabel / Augustin, Marc / Zwingmann, Christian

    Psychosoziale und medizinische Rehabilitation

    2022  Volume 35, Issue 3 = 119, Page(s) 98

    Language German
    Document type Article
    ZDB-ID 3094133-7
    ISSN 0933-842X ; 2750-1353
    Database Current Contents Medicine

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  8. Article: Sind Wirkfaktoren der Psychotherapie auch für die psychosoziale Beratung relevant? Eine Befragung in Tagesstätten für Menschen mit einer psychischen Erkrankung

    Sprandel, M. Isabel / Augustin, Marc / Zwingmann, Christian

    PSMR - Psychosoziale und Medizinische Rehabilitation

    2022  Volume 35, Issue 3, Page(s) 98–107

    Abstract: Psychosoziale Beratung ist ein zentrales Handlungsfeld in der Sozialen Arbeit. Es wurde in seiner Methodik und Gesprächsführung stark von der Psychotherapie beeinflusst. Wirkfaktoren-Modelle in der Psychotherapieforschung beschreiben die Annahme, dass ... ...

    Title translation Are outcome factors of psychotherapy also relevant for psychosocial counseling? A survey in day care centers for people with a mental illness
    Abstract Psychosoziale Beratung ist ein zentrales Handlungsfeld in der Sozialen Arbeit. Es wurde in seiner Methodik und Gesprächsführung stark von der Psychotherapie beeinflusst. Wirkfaktoren-Modelle in der Psychotherapieforschung beschreiben die Annahme, dass die Wirksamkeit von Psychotherapie auf bestimmte Faktoren zurückgeht. Anhand einer querschnittlichen Fragebogenstudie in Tagesstätten für Menschen mit einer psychischen Erkrankung wurde untersucht, inwieweit die Wirkfaktoren der Psychotherapie aus Sicht der Beteiligten in der psychosozialen Beratung Sozialer Arbeit vorkommen und mit Einschätzungen der Wirksamkeit in Verbindung stehen. Bei der Operationalisierung der Wirkfaktoren wurde das Modell nach Grawe et al. (1994) herangezogen. Einschätzungen der Klientinnen und Klienten (N = 48) zeigen, dass die Wirkfaktoren der Psychotherapie auch in der psychosozialen Beratung enthalten sind und substanziell mit Zielerreichungen als Indikatoren der Wirksamkeit korrelieren.
    Keywords Beratung ; Counseling ; Day Care Centers ; Mental Disorders ; Psychische Störungen ; Psychotherapeutic Outcomes ; Psychotherapeutic Processes ; Psychotherapeutische Prozesse ; Psychotherapieergebnisse ; Social Casework ; Sozialarbeit ; Tagesstätten ; Therapieerfolgskontrolle ; Therapieergebnisse ; Treatment Effectiveness Evaluation ; Treatment Outcomes
    Language German
    Document type Article
    ZDB-ID 624768-4
    ISSN 0933-842X
    ISSN 0933-842X
    Database PSYNDEX

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  9. Article: Effects of the antidepressant mirtazapine on the swimming behaviour and gene expression rate of Danio rerio embryos – Is the sedating effect seen in humans also evident for fish?

    Gundlach, Michael / Augustin, Marc / Smith, Kilian E.C / Kämpfer, David / Paulzen, Michael / Hollert, Henner

    Science of the total environment. 2021 Oct. 20, v. 792

    2021  

    Abstract: In the last decade, mirtazapine has become an important antidepressant in clinical use and has also been found at many different environmental sampling sites. Several homologies between the zebrafish Danio rerio and humans, combined with a number of ... ...

    Abstract In the last decade, mirtazapine has become an important antidepressant in clinical use and has also been found at many different environmental sampling sites. Several homologies between the zebrafish Danio rerio and humans, combined with a number of advantages for behavioural and gene expression research using zebrafish embryos, make their use for the analysis of mirtazapine appropriate. The sedative effect of mirtazapine in humans was also found for a specific concentration range in zebrafish embryos (1333.4 μg/L – 2666.9 μg/L). Specifically, 116 hpf old zebrafish embryos showed a reduced swimming distance when exposed to 1334.4 μg/L mirtazapine. Furthermore, changes at the gene regulatory level could be measured (1333.4 μg/L), in particular in the superordinate regulatory systems. For selected transporters of all regulatory systems, an up regulation of the genes by a factor of more than five times could be measured at the highest mirtazapine exposure concentration that was tested. Finally, studies on the protein levels demonstrated an increase in acetylcholinesterase activity for several exposure concentrations(83.3 μg/L and 666.7 μg/L). The physiological changes in zebrafish embryos caused by mirtazapine demonstrate the relevance of these types of studies in aquatic non-target organisms. Such neuroactive substances could pose a potential risk for aquatic organisms below the previously considered concentration threshold for morphological effects.
    Keywords Danio rerio ; acetylcholinesterase ; antidepressants ; environment ; fish ; gene expression ; genes ; risk ; sedatives
    Language English
    Dates of publication 2021-1020
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2021.148368
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  10. Article ; Online: Influence of Kidney Function on Serum Risperidone Concentrations in Patients Treated With Risperidone.

    Gründer, Philipp / Augustin, Marc / Paulzen, Michael / Gründer, Gerhard

    The Journal of clinical psychiatry

    2019  Volume 80, Issue 6

    Abstract: Objective: Risperidone is one of the most commonly prescribed antipsychotics worldwide. Its main metabolite, 9-hydroxyrisperidone (9-OH-RIS), is excreted renally. The present study examined the relationship of kidney function and serum risperidone ... ...

    Abstract Objective: Risperidone is one of the most commonly prescribed antipsychotics worldwide. Its main metabolite, 9-hydroxyrisperidone (9-OH-RIS), is excreted renally. The present study examined the relationship of kidney function and serum risperidone concentrations in a large sample of risperidone-treated patients.
    Methods: Serum concentrations of risperidone and its active metabolite 9-OH-RIS, as well as creatinine concentrations, from which glomerular filtration rates (GFRs) were estimated, were determined in 175 risperidone-medicated patients (75 female, 100 male). Data were collected between July 2013 and December 2016. Patients were clustered in 4 groups according to their estimated GFR (eGFR) (30-60; > 60-90; > 90-120; and > 120 mL/min/1.73 m²), and serum concentrations of risperidone and 9-OH-RIS and their sum (active moiety [AM]) were compared groupwise. Additionally, serum concentrations were correlated with kidney function.
    Results: Dose-corrected AM and dose-corrected 9-OH-RIS concentrations were significantly higher in patients with an eGFR of 30-60 mL/min/1.73 m² than in patients with an eGFR > 90-120 mL/min/1.73 m² (P < .001 for dose-corrected AM and P = .001 for dose-corrected 9-OH-RIS) or > 120 mL/min/1.73 m² (P = .036 and .021, respectively). Dose-corrected AM levels were more than doubled in the 30-60 mL/min/1.73 m² group compared to the > 90-120 mL/min/1.73 m² group (mean ± SD = 22.2 ± 14.0 [ng/mL]/[mg/d] vs 10.1 ± 7.7 [ng/mL]/[mg/d]). In the total group, eGFR and dose-corrected 9-OH-RIS and dose-corrected AM were weakly but statistically significantly correlated (Spearman rank correlation coefficient [Rs] = -0.2, P = .004, and Rs = -0.17, P = .01, respectively).
    Conclusions: Kidney function is an important determinant of risperidone clearance. These data suggest reducing the risperidone dose by 50% in patients with a GFR below 60 mL/min.
    MeSH term(s) Adult ; Aged ; Dose-Response Relationship, Drug ; Female ; Germany ; Humans ; Kidney Function Tests ; Male ; Middle Aged ; Paliperidone Palmitate/blood ; Psychotic Disorders/blood ; Psychotic Disorders/drug therapy ; Renal Elimination/drug effects ; Renal Elimination/physiology ; Risperidone/pharmacokinetics ; Risperidone/therapeutic use ; Schizophrenia/blood ; Schizophrenia/drug therapy
    Chemical Substances Risperidone (L6UH7ZF8HC) ; Paliperidone Palmitate (R8P8USM8FR)
    Language English
    Publishing date 2019-11-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.19m12890
    Database MEDical Literature Analysis and Retrieval System OnLINE

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