LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 180

Search options

  1. Book ; Online: Fast facts

    O'Brien, Mary / Besse, Benjamin / Awad, Mark M.

    non-small-cell lung cancer

    (Fast facts)

    2022  

    Abstract: Despite an overall decrease in tobacco use, lung cancer (80-85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide. ...

    Title variant Non-small-cell-lung cancer
    Author's details Mary O'Brien, Benjamin Besse, Mark M Awad
    Series title Fast facts
    Abstract Despite an overall decrease in tobacco use, lung cancer (80-85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide.
    MeSH term(s) Lung Neoplasms
    Keywords Lungs/Cancer
    Subject code 616.99424
    Language English
    Dates of publication 2022-2022
    Size 1 online resource (146 pages) :, color illustrations
    Edition 2nd ed.
    Publisher S. Karger Publishers Ltd
    Publishing place Abingdon, Oxford
    Document type Book ; Online
    Note R2 Digital Library does not include index.
    ISBN 3-318-07088-2 ; 3-318-07010-6 ; 978-3-318-07088-0 ; 978-3-318-07010-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Kategorien

  2. Article ; Online: Letter to the Editor: Reply to Kus and Aktas.

    Alessi, Joao V / Awad, Mark M

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 8, Page(s) e84–e85

    Language English
    Publishing date 2023-07-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.05.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Atezolizumab Plus Bevacizumab in TMB-High Non-Small Cell Lung Cancers-The Hunt for Predictive Biomarkers to Optimize Treatment Selection.

    Ricciuti, Biagio / Awad, Mark M

    JAMA oncology

    2022  Volume 9, Issue 3, Page(s) 353–354

    MeSH term(s) Humans ; Bevacizumab/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Lung Neoplasms/drug therapy ; Biomarkers ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Liver Neoplasms/drug therapy
    Chemical Substances Bevacizumab (2S9ZZM9Q9V) ; atezolizumab (52CMI0WC3Y) ; Biomarkers
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2022.5801
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Reply to Kus and Aktas.

    Ricciuti, Biagio / Awad, Mark M

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2022  Volume 17, Issue 6, Page(s) e64–e65

    MeSH term(s) Humans ; Lung Neoplasms
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2022.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Increased Tumor Mutation Burden Levels and Sensitivity of Non-Small Cell Lung Cancer to PD-L1 Blockade-Reply.

    Ricciuti, Biagio / Wang, Xinan / Awad, Mark M

    JAMA oncology

    2023  Volume 9, Issue 4, Page(s) 570–571

    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; B7-H1 Antigen/genetics ; Antineoplastic Agents, Immunological/therapeutic use ; Biomarkers, Tumor ; Mutation ; Immunotherapy
    Chemical Substances B7-H1 Antigen ; Antineoplastic Agents, Immunological ; Biomarkers, Tumor
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2374-2445
    ISSN (online) 2374-2445
    DOI 10.1001/jamaoncol.2022.7589
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Popliteal aneurysm repair using the posterior approach.

    Bowles, Bradley / Awad, Mark / Smeds, Matthew R

    Journal of vascular surgery cases and innovative techniques

    2022  Volume 8, Issue 4, Page(s) 574–575

    Language English
    Publishing date 2022-09-08
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4287
    ISSN 2468-4287
    DOI 10.1016/j.jvscit.2022.08.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Immunotherapy in lung cancer: effective for patients with poor performance status?

    Alessi, Joao V / Awad, Mark M

    The Lancet. Respiratory medicine

    2020  Volume 8, Issue 9, Page(s) 838–839

    MeSH term(s) Antibodies, Monoclonal, Humanized ; Carcinoma, Non-Small-Cell Lung ; Humans ; Immunotherapy ; Lung Neoplasms
    Chemical Substances Antibodies, Monoclonal, Humanized ; pembrolizumab (DPT0O3T46P)
    Language English
    Publishing date 2020-03-19
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(20)30107-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Reply to Cortellini A.

    Ricciuti, Biagio / Awad, Mark M

    JTO clinical and research reports

    2020  Volume 1, Issue 4, Page(s) 100095

    Language English
    Publishing date 2020-11-21
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3643
    ISSN (online) 2666-3643
    DOI 10.1016/j.jtocrr.2020.100095
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: What Is the Standard First-Line Treatment for Advanced Non-Small Cell Lung Cancer?

    Ricciuti, Biagio / Awad, Mark M

    Cancer journal (Sudbury, Mass.)

    2020  Volume 26, Issue 6, Page(s) 485–495

    Abstract: The initial treatment regimens for advanced non-small cell lung cancer (NSCLC) have drastically evolved over the last 15 years with the rapid development of improved genomic sequencing technologies and the emergence of immune checkpoint inhibitors. ... ...

    Abstract The initial treatment regimens for advanced non-small cell lung cancer (NSCLC) have drastically evolved over the last 15 years with the rapid development of improved genomic sequencing technologies and the emergence of immune checkpoint inhibitors. Highly active oral kinase inhibitors are now approved for several molecularly defined subsets of NSCLC, including those harboring alterations in the EGFR, ALK, ROS1, BRAF, MET, RET, and NTRK genes, although acquired resistance to these targeted therapies remains a significant clinical challenge. In lung cancers lacking targetable mutations, programmed death 1/programmed death ligand 1 immune checkpoint inhibitors, used alone or in combination with cytotoxic T-lymphocyte-associated protein 4 inhibitors and/or cytotoxic chemotherapy, have led to meaningful improvements in overall survival. With many therapeutic options available to patients, here we review the recommended frontline treatment regimens for advanced NSCLC with and without targetable genomic drivers.
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Molecular Targeted Therapy ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Proto-Oncogene Proteins
    Chemical Substances Immune Checkpoint Inhibitors ; Proto-Oncogene Proteins ; Protein-Tyrosine Kinases (EC 2.7.10.1)
    Language English
    Publishing date 2020-12-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2018400-1
    ISSN 1540-336X ; 1528-9117 ; 1081-4442
    ISSN (online) 1540-336X
    ISSN 1528-9117 ; 1081-4442
    DOI 10.1097/PPO.0000000000000489
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Impaired c-Met Receptor Degradation Mediated by MET Exon 14 Mutations in Non-Small-Cell Lung Cancer.

    Awad, Mark M

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2016  Volume 34, Issue 8, Page(s) 879–881

    MeSH term(s) Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Exons ; Gene Amplification ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mutation ; Proto-Oncogene Proteins c-met/genetics ; Proto-Oncogene Proteins c-met/metabolism
    Chemical Substances MET protein, human (EC 2.7.10.1) ; Proto-Oncogene Proteins c-met (EC 2.7.10.1)
    Language English
    Publishing date 2016-03-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2015.64.2777
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top