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  1. Article ; Online: Evidence of Rift Valley Fever Virus Circulation in Livestock and Herders in Southern Ghana.

    Johnson, Sherry Ama Mawuko / Asmah, Richard / Awuni, Joseph Adongo / Tasiame, William / Mensah, Gloria Ivy / Paweska, Janusz T / Weyer, Jacqueline / Hellferscee, Orienka / Thompson, Peter N

    Viruses

    2023  Volume 15, Issue 6

    Abstract: Rift Valley fever (RVF) is a re-emerging zoonotic disease of domestic ruminants and humans. While neighbouring countries have reported outbreaks of RVF, Ghana has not yet identified any cases. The aim of this study was to determine whether RVF virus ( ... ...

    Abstract Rift Valley fever (RVF) is a re-emerging zoonotic disease of domestic ruminants and humans. While neighbouring countries have reported outbreaks of RVF, Ghana has not yet identified any cases. The aim of this study was to determine whether RVF virus (RVFV) was circulating in livestock and herders in the southern part of Ghana, to estimate its seroprevalence, and to identify associated risk factors. The study surveyed 165 livestock farms randomly selected from two districts in southern Ghana. Serum samples of 253 goats, 246 sheep, 220 cattle, and 157 herdsmen were tested to detect IgG and IgM antibodies against RVFV. The overall seroprevalence of anti-RVF antibodies in livestock was 13.1% and 30.9% of farms had RVFV seropositive animals. The species-specific prevalence was 24.1% in cattle, 8.5% in sheep, and 7.9% in goats. A RVFV IgG seroprevalence of 17.8% was found among the ruminant herders, with 8.3% of all herders being IgM positive. RVFV was shown, for the first time, to have been circulating in southern Ghana, with evidence of a recent outbreak in Kwahu East; however, it was clinically undetected despite significant recent human exposure. A One Health approach is recommended to better understand RVF epidemiology and socio-economic impact in Ghana.
    MeSH term(s) Animals ; Cattle ; Sheep ; Humans ; Rift Valley fever virus ; Livestock ; Seroepidemiologic Studies ; Ghana/epidemiology ; Antibodies, Viral ; Cattle Diseases ; Sheep Diseases/epidemiology ; Rift Valley Fever ; Ruminants ; Goats ; Immunoglobulin M ; Immunoglobulin G
    Chemical Substances Antibodies, Viral ; Immunoglobulin M ; Immunoglobulin G
    Language English
    Publishing date 2023-06-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15061346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detection of avian influenza virus: a comparative study of the in silico and in vitro performances of current RT-qPCR assays.

    Laconi, Andrea / Fortin, Andrea / Bedendo, Giulia / Shibata, Akihiro / Sakoda, Yoshihiro / Awuni, Joseph Adongo / Go-Maro, Emilie / Arafa, Abdelsatar / Maken Ali, Ali Safar / Terregino, Calogero / Monne, Isabella

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 8441

    Abstract: Avian influenza viruses (AIV) are negative sense RNA viruses posing a major threat to the poultry industry worldwide, with the potential to spread to mammals, including humans; hence, an accurate and rapid AIV diagnosis is essential. To date AIV ... ...

    Abstract Avian influenza viruses (AIV) are negative sense RNA viruses posing a major threat to the poultry industry worldwide, with the potential to spread to mammals, including humans; hence, an accurate and rapid AIV diagnosis is essential. To date AIV detection relies on molecular methods, mainly RT-qPCR directed against AIV M gene segment. The evolution of AIV represents a relevant issue in diagnostic RT-qPCR due to possible mispriming and/or probe-binding failures resulting in false negative results. Consequently, RT-qPCR for AIV detection should be periodically re-assessed both in silico and in vitro. To this end, a specific workflow was developed to evaluate in silico the complementarity of primers and probes of four published RT-qPCR protocols to their target regions. The four assays and one commercially available kit for AIV detection were evaluated both for their analytical sensitivity using eight different viral dilution panels and for their diagnostic performances against clinical specimens of known infectious status. Differences were observed among the tests under evaluation, both in terms of analytical sensitivity and of diagnostic performances. This finding confirms the importance of continuously monitoring the primers and probes complementarity to their binding regions.
    MeSH term(s) Animals ; Birds ; Computer Simulation ; Genetic Variation ; In Vitro Techniques ; Influenza A virus/classification ; Influenza A virus/genetics ; Influenza A virus/isolation & purification ; Influenza in Birds/diagnosis ; Influenza in Birds/genetics ; Influenza in Birds/virology ; RNA, Viral/analysis ; RNA, Viral/genetics ; ROC Curve ; Real-Time Polymerase Chain Reaction/methods ; Viral Proteins/genetics
    Chemical Substances RNA, Viral ; Viral Proteins
    Language English
    Publishing date 2020-05-21
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-64003-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of Avian Influenza on Village Poultry Production Globally

    Alders, Robyn / Awuni, Joseph Adongo / Bagnol, Brigitte / Farrell, Penny / de Haan, Nicolene

    Ecohealth. 2014 Mar., v. 11, no. 1

    2014  

    Abstract: Village poultry and their owners were frequently implicated in disease transmission in the early days of the highly pathogenic avian influenza (HPAI) H5N1 pandemic. With improved understanding of the epidemiology of the disease, it was recognized that ... ...

    Abstract Village poultry and their owners were frequently implicated in disease transmission in the early days of the highly pathogenic avian influenza (HPAI) H5N1 pandemic. With improved understanding of the epidemiology of the disease, it was recognized that village poultry raised under extensive conditions pose less of a threat than intensively raised poultry of homogeneous genetic stock with poor biosecurity. This paper provides an overview of village poultry production and the multiple ways that the HPAI H5N1 pandemic has impacted on village poultry, their owners, and the traders whose livelihoods are intimately linked to these birds. It reviews impact in terms of gender and cultural issues; food security; village poultry value chains; approaches to biosecurity; marketing; poultry disease prevention and control; compensation; genetic diversity; poultry as part of livelihood strategies; and effective communication. It concludes on a positive note that there is growing awareness amongst animal health providers of the importance of facilitating culturally sensitive dialogue to develop HPAI prevention and control options.
    Keywords animal health ; avian influenza ; biosecurity ; birds ; disease prevention ; disease transmission ; food security ; gender ; genetic variation ; livelihood ; marketing ; pandemic ; poultry ; poultry production
    Language English
    Dates of publication 2014-03
    Size p. 63-72.
    Publishing place Springer-Verlag
    Document type Article
    ZDB-ID 2164327-1
    ISSN 1612-9202
    ISSN 1612-9202
    DOI 10.1007/s10393-013-0867-x
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7528: Show issues

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  4. Article ; Online: Impact of avian influenza on village poultry production globally.

    Alders, Robyn / Awuni, Joseph Adongo / Bagnol, Brigitte / Farrell, Penny / de Haan, Nicolene

    EcoHealth

    2013  Volume 11, Issue 1, Page(s) 63–72

    Abstract: Village poultry and their owners were frequently implicated in disease transmission in the early days of the highly pathogenic avian influenza (HPAI) H5N1 pandemic. With improved understanding of the epidemiology of the disease, it was recognized that ... ...

    Abstract Village poultry and their owners were frequently implicated in disease transmission in the early days of the highly pathogenic avian influenza (HPAI) H5N1 pandemic. With improved understanding of the epidemiology of the disease, it was recognized that village poultry raised under extensive conditions pose less of a threat than intensively raised poultry of homogeneous genetic stock with poor biosecurity. This paper provides an overview of village poultry production and the multiple ways that the HPAI H5N1 pandemic has impacted on village poultry, their owners, and the traders whose livelihoods are intimately linked to these birds. It reviews impact in terms of gender and cultural issues; food security; village poultry value chains; approaches to biosecurity; marketing; poultry disease prevention and control; compensation; genetic diversity; poultry as part of livelihood strategies; and effective communication. It concludes on a positive note that there is growing awareness amongst animal health providers of the importance of facilitating culturally sensitive dialogue to develop HPAI prevention and control options.
    MeSH term(s) Animals ; Commerce ; Developing Countries/economics ; Disease Outbreaks/economics ; Disease Outbreaks/veterinary ; Food Chain ; Food Supply/economics ; Indonesia/epidemiology ; Influenza A Virus, H5N1 Subtype/pathogenicity ; Influenza in Birds/epidemiology ; Influenza in Birds/prevention & control ; Influenza in Birds/virology ; Male ; Poultry ; Poultry Diseases/economics ; Poultry Diseases/prevention & control ; Poultry Diseases/virology ; Poultry Products/economics ; Risk Factors ; Rural Population ; Sex Factors ; Socioeconomic Factors ; Vietnam/epidemiology
    Language English
    Publishing date 2013-10-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2164327-1
    ISSN 1612-9210 ; 1612-9202
    ISSN (online) 1612-9210
    ISSN 1612-9202
    DOI 10.1007/s10393-013-0867-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7528: Show issues
    Zs Bio Ecohealth: Show issues

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  5. Article ; Online: Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015.

    Tassoni, Luca / Fusaro, Alice / Milani, Adelaide / Lemey, Philippe / Awuni, Joseph Adongo / Sedor, Victoria Bernice / Dogbey, Otilia / Commey, Abraham Nii Okai / Meseko, Clement / Joannis, Tony / Minoungou, Germaine L / Ouattara, Lassina / Haido, Abdoul Malick / Cisse-Aman, Diarra / Couacy-Hymann, Emmanuel / Dauphin, Gwenaelle / Cattoli, Giovanni / Monne, Isabella

    Emerging infectious diseases

    2016  Volume 22, Issue 12, Page(s) 2132–2136

    Abstract: To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. ... ...

    Abstract To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2212.160578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Disentangling the role of Africa in the global spread of H5 highly pathogenic avian influenza.

    Fusaro, Alice / Zecchin, Bianca / Vrancken, Bram / Abolnik, Celia / Ademun, Rose / Alassane, Abdou / Arafa, Abdelsatar / Awuni, Joseph Adongo / Couacy-Hymann, Emmanuel / Coulibaly, M ' Bétiégué / Gaidet, Nicolas / Go-Maro, Emilie / Joannis, Tony / Jumbo, Simon Dickmu / Minoungou, Germaine / Meseko, Clement / Souley, Maman Moutari / Ndumu, Deo Birungi / Shittu, Ismaila /
    Twabela, Augustin / Wade, Abel / Wiersma, Lidewij / Akpeli, Yao P / Zamperin, Gianpiero / Milani, Adelaide / Lemey, Philippe / Monne, Isabella

    Nature communications

    2019  Volume 10, Issue 1, Page(s) 5310

    Abstract: The role of Africa in the dynamics of the global spread of a zoonotic and economically-important virus, such as the highly pathogenic avian influenza (HPAI) H5Nx of the Gs/GD lineage, remains unexplored. Here we characterise the spatiotemporal patterns ... ...

    Abstract The role of Africa in the dynamics of the global spread of a zoonotic and economically-important virus, such as the highly pathogenic avian influenza (HPAI) H5Nx of the Gs/GD lineage, remains unexplored. Here we characterise the spatiotemporal patterns of virus diffusion during three HPAI H5Nx intercontinental epidemic waves and demonstrate that Africa mainly acted as an ecological sink of the HPAI H5Nx viruses. A joint analysis of host dynamics and continuous spatial diffusion indicates that poultry trade as well as wild bird migrations have contributed to the virus spreading into Africa, with West Africa acting as a crucial hotspot for virus introduction and dissemination into the continent. We demonstrate varying paths of avian influenza incursions into Africa as well as virus spread within Africa over time, which reveal that virus expansion is a complex phenomenon, shaped by an intricate interplay between avian host ecology, virus characteristics and environmental variables.
    MeSH term(s) Africa ; Africa, Western ; Animals ; Humans ; Influenza A Virus, H5N1 Subtype/genetics ; Influenza A Virus, H5N8 Subtype/genetics ; Influenza A virus/genetics ; Influenza in Birds/economics ; Influenza in Birds/epidemiology ; Influenza in Birds/transmission ; Influenza in Birds/virology ; Influenza, Human/economics ; Influenza, Human/epidemiology ; Influenza, Human/transmission ; Influenza, Human/virology ; Phylogeny ; Poultry ; Poultry Diseases/economics ; Poultry Diseases/epidemiology ; Poultry Diseases/transmission ; Poultry Diseases/virology
    Language English
    Publishing date 2019-11-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-019-13287-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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