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Article ; Online: Stable D-xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic β-amino acids.

Balo, Rosalino / Fernández, Alberto G / Chopdat, Adam / Ayadi, Soufian El / Kato, Atsushi / Estévez, Ramón J / Fleet, George W J / Estévez, Juan C

Organic & biomolecular chemistry

2022  Volume 20, Issue 47, Page(s) 9447–9459

Abstract: Double nucleophilic displacement of D-xylo-ditriflate by amines, water and alkyl cyanoacetates, respectively, gave a series of bicyclic divergent intermediates for the synthesis of a wide range of highly functionalized targets, including hydroxylated ... ...

Abstract Double nucleophilic displacement of D-xylo-ditriflate by amines, water and alkyl cyanoacetates, respectively, gave a series of bicyclic divergent intermediates for the synthesis of a wide range of highly functionalized targets, including hydroxylated prolines, pyrrolidines, furanoic acids, and cyclopentanes.
MeSH term(s) Proline ; Pyrrolidines ; Xylose ; Carboxylic Acids
Chemical Substances Proline (9DLQ4CIU6V) ; Pyrrolidines ; Xylose (A1TA934AKO) ; Carboxylic Acids
Language English
Publishing date 2022-12-07
Publishing country England
Document type Journal Article
ZDB-ID 2097583-1
ISSN 1477-0539 ; 1477-0520
ISSN (online) 1477-0539
ISSN 1477-0520
DOI 10.1039/d2ob01255c
Database MEDical Literature Analysis and Retrieval System OnLINE

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