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  1. Article ; Online: Covid-19: What is the best approach in gynecological oncology patient management during the coronavirus pandemic?

    Hasanzadeh, Malihe / Azad, Afrooz / Farazestanian, Marjaneh / Mousavi Seresht, Leila

    Asia-Pacific journal of clinical oncology

    2020  Volume 17, Issue 4, Page(s) 312–320

    Abstract: Coronavirus (COVID-19) infection is a new major concern and a global emergency in almost all countries worldwide; due to the higher sensibility of cancer patients, they are more susceptible to severe and fatal infections, being nearly 10 times more ... ...

    Abstract Coronavirus (COVID-19) infection is a new major concern and a global emergency in almost all countries worldwide; due to the higher sensibility of cancer patients, they are more susceptible to severe and fatal infections, being nearly 10 times more likely than in healthy individuals infected with this virus. Although the aggressive nature of a cancer is a matter of concern, our exact role as oncologists in this time of restricted resources is not fully clarified. Regarding some consensus recommendation for postponing surgery, there is still an essential need for a single approved protocol regarding each type of malignancy. Iran, as one of the first involved countries in this crisis in Asia, which also has a high prevalence of gynecological malignancies, will certainly require an individualized decision-making schedule based on the most accepted global consensus opinion. Considering our restricted health system resources, herein we tried to introduce a logical gynecologic cancer management protocol based on the stage and survival expectancy of each tumor, along with reviewing all recent recommendations. The limited statistics published in this short period of time have obliged us to mainly focus on expert opinions, and the individualized clinical judgments should be agreed upon by multidisciplinary tumor board consensus. In conclusion, the COVID-19 pandemic overshadows all aspects of medicine, and decision making in gynecological oncology patients requires precise and appropriate judgment based on the available local resources.
    MeSH term(s) COVID-19 ; Female ; Genital Neoplasms, Female/therapy ; Gynecology ; Humans ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-20
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2187409-8
    ISSN 1743-7563 ; 1743-7555
    ISSN (online) 1743-7563
    ISSN 1743-7555
    DOI 10.1111/ajco.13476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unusual location of sentinel node in the inferior gluteal region in a patient with ovarian tumor.

    Farazestanian, Marjaneh / Ataei Nakhaei, Saeedeh / Azad, Afrooz / Jahani, Najmeh / Sadeghi, Ramin

    Revista espanola de medicina nuclear e imagen molecular

    2021  Volume 41 Suppl 1, Page(s) S6–S7

    MeSH term(s) Buttocks/diagnostic imaging ; Buttocks/pathology ; Female ; Humans ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/pathology ; Ovarian Neoplasms/surgery ; Sentinel Lymph Node/diagnostic imaging ; Sentinel Lymph Node/pathology ; Sentinel Lymph Node Biopsy
    Language English
    Publishing date 2021-02-13
    Publishing country Spain
    Document type Journal Article
    ISSN 2253-8089
    ISSN (online) 2253-8089
    DOI 10.1016/j.remnie.2020.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Covid-19: What is the best approach in gynecological oncology patient management during the coronavirus pandemic?

    Hasanzadeh, Malihe / Azad, Afrooz / Farazestanian, Marjaneh / Mousavi Seresht, Leila

    Asia Pac. j. clin.oncol

    Abstract: Coronavirus (COVID-19) infection is a new major concern and a global emergency in almost all countries worldwide; due to the higher sensibility of cancer patients, they are more susceptible to severe and fatal infections, being nearly 10 times more ... ...

    Abstract Coronavirus (COVID-19) infection is a new major concern and a global emergency in almost all countries worldwide; due to the higher sensibility of cancer patients, they are more susceptible to severe and fatal infections, being nearly 10 times more likely than in healthy individuals infected with this virus. Although the aggressive nature of a cancer is a matter of concern, our exact role as oncologists in this time of restricted resources is not fully clarified. Regarding some consensus recommendation for postponing surgery, there is still an essential need for a single approved protocol regarding each type of malignancy. Iran, as one of the first involved countries in this crisis in Asia, which also has a high prevalence of gynecological malignancies, will certainly require an individualized decision-making schedule based on the most accepted global consensus opinion. Considering our restricted health system resources, herein we tried to introduce a logical gynecologic cancer management protocol based on the stage and survival expectancy of each tumor, along with reviewing all recent recommendations. The limited statistics published in this short period of time have obliged us to mainly focus on expert opinions, and the individualized clinical judgments should be agreed upon by multidisciplinary tumor board consensus. In conclusion, the COVID-19 pandemic overshadows all aspects of medicine, and decision making in gynecological oncology patients requires precise and appropriate judgment based on the available local resources.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #880875
    Database COVID19

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  4. Article ; Online: Covid‐19

    Hasanzadeh, Malihe / Azad, Afrooz / Farazestanian, Marjaneh / Mousavi Seresht, Leila

    Asia-Pacific Journal of Clinical Oncology ; ISSN 1743-7555 1743-7563

    What is the best approach in gynecological oncology patient management during the coronavirus pandemic?

    2020  

    Keywords Oncology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/ajco.13476
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Effects of Phytoestrogens in Alleviating the Menopausal Symptoms: A Systematic Review and Meta-Analysis.

    Saghafi, Nafiseh / Ghazanfarpour, Masoumeh / Sadeghi, Ramin / Hosseini Najarkolaei, Azadeh / Ghaffarian Omid, Maryam / Azad, Afrooz / Bakhtiyari, Mahmood / Hosseini Najarkolaei, Elnaz

    Iranian journal of pharmaceutical research : IJPR

    2018  Volume 16, Issue Suppl, Page(s) 99–111

    Abstract: The aim of this study was to perform a meta-analysis of high-quality, randomized, controlled trials (RCTs), to investigate the effectiveness of phytoestrogens in alleviating the menopausal symptoms (vaginal atrophy). Variety of databases including PubMed, ...

    Abstract The aim of this study was to perform a meta-analysis of high-quality, randomized, controlled trials (RCTs), to investigate the effectiveness of phytoestrogens in alleviating the menopausal symptoms (vaginal atrophy). Variety of databases including PubMed, Scopus, and Cochrane Central Register of Controlled Trials (CCRCT) were searched up to May 2015 according to the below-mentioned pre-specified search strategy and using the relevant MeSH terms. The mean difference was applied as an estimate of the main effect size. Moreover, due to the considerable heterogeneity among studies, the random-effects model was used to obtain the pooled effect size derived from primary studies. Results showed that while the standardized mean difference of vaginal cell maturation index was increased up to 0.164 percent (with the confidence interval at 95%: (-0.419-0.746), but this increase was not statistically significant (
    Language English
    Publishing date 2018-05-22
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2578271-X
    ISSN 1726-6890 ; 1735-0328 ; 1735-0328
    ISSN (online) 1726-6890 ; 1735-0328
    ISSN 1735-0328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia.

    Kariminejad, Ariana / Szenker-Ravi, Emmanuelle / Lekszas, Caroline / Tajsharghi, Homa / Moslemi, Ali-Reza / Naert, Thomas / Tran, Hong Thi / Ahangari, Fatemeh / Rajaei, Minoo / Nasseri, Mojila / Haaf, Thomas / Azad, Afrooz / Superti-Furga, Andrea / Maroofian, Reza / Ghaderi-Sohi, Siavash / Najmabadi, Hossein / Abbaszadegan, Mohammad Reza / Vleminckx, Kris / Nikuei, Pooneh /
    Reversade, Bruno

    American journal of human genetics

    2019  Volume 105, Issue 6, Page(s) 1294–1301

    Abstract: The development of hindlimbs in tetrapod species relies specifically on the transcription factor TBX4. In humans, heterozygous loss-of-function TBX4 mutations cause dominant small patella syndrome (SPS) due to haploinsufficiency. Here, we characterize a ... ...

    Abstract The development of hindlimbs in tetrapod species relies specifically on the transcription factor TBX4. In humans, heterozygous loss-of-function TBX4 mutations cause dominant small patella syndrome (SPS) due to haploinsufficiency. Here, we characterize a striking clinical entity in four fetuses with complete posterior amelia with pelvis and pulmonary hypoplasia (PAPPA). Through exome sequencing, we find that PAPPA syndrome is caused by homozygous TBX4 inactivating mutations during embryogenesis in humans. In two consanguineous couples, we uncover distinct germline TBX4 coding mutations, p.Tyr113
    MeSH term(s) Abnormalities, Multiple/etiology ; Abnormalities, Multiple/pathology ; Adolescent ; Bone Diseases, Developmental/etiology ; Bone Diseases, Developmental/pathology ; Child ; Ectromelia/etiology ; Ectromelia/pathology ; Female ; Hip/abnormalities ; Hip/pathology ; Homozygote ; Humans ; Ischium/abnormalities ; Ischium/pathology ; Loss of Function Mutation ; Lung/abnormalities ; Lung/pathology ; Lung Diseases/etiology ; Lung Diseases/pathology ; Male ; Patella/abnormalities ; Patella/pathology ; Pedigree ; Pelvis/abnormalities ; Pelvis/pathology ; Prognosis ; T-Box Domain Proteins/genetics
    Chemical Substances T-Box Domain Proteins ; TBX4 protein, human
    Language English
    Publishing date 2019-11-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219384-x
    ISSN 1537-6605 ; 0002-9297
    ISSN (online) 1537-6605
    ISSN 0002-9297
    DOI 10.1016/j.ajhg.2019.10.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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