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  1. Article ; Online: Cardiac magnetic resonance assessment of diastolic dysfunction in acute coronary syndrome.

    Azarisman, Shah M / Teo, Karen S / Worthley, Matthew I / Worthley, Stephen G

    The Journal of international medical research

    2017  Volume 45, Issue 6, Page(s) 1680–1692

    Abstract: Chest pain is an important presenting symptom. However, few cases of chest pain are diagnosed as acute coronary syndrome (ACS) in the acute setting. This results in frequent inappropriate discharge and major delay in treatment for patients with ... ...

    Abstract Chest pain is an important presenting symptom. However, few cases of chest pain are diagnosed as acute coronary syndrome (ACS) in the acute setting. This results in frequent inappropriate discharge and major delay in treatment for patients with underlying ACS. The conventional methods of assessing ACS, which include electrocardiography and serological markers of infarct, can take time to manifest. Recent studies have investigated more sensitive and specific imaging modalities that can be used. Diastolic dysfunction occurs early following coronary artery occlusion and its detection is useful in confirming the diagnosis, risk stratification, and prognosis post-ACS. Cardiac magnetic resonance provides a single imaging modality for comprehensive evaluation of chest pain in the acute setting. In particular, cardiac magnetic resonance has many imaging techniques that assess diastolic dysfunction post-coronary artery occlusion. Techniques such as measurement of left atrial size, mitral inflow, and mitral annular and pulmonary vein flow velocities with phase-contrast imaging enable general assessment of ventricular diastolic function. More novel imaging techniques, such as T2-weighted imaging for oedema, T1 mapping, and myocardial tagging, allow early determination of regional diastolic dysfunction and oedema. These findings may correspond to specific infarcted arteries that may be used to tailor eventual percutaneous coronary artery intervention.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/physiopathology ; Clinical Trials as Topic ; Diastole ; Humans ; Magnetic Resonance Imaging ; Myocardium/pathology ; Regional Blood Flow
    Language English
    Publishing date 2017-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/0300060517698265
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 925: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Impact of educational outreach intervention on enhancing health care providers' knowledge about statin therapy prescribing in Malaysian patients with type 2 diabetes mellitus.

    Elnaem, Mohamed Hassan / Nik Mohamed, Mohamad Haniki / Zaman Huri, Hasniza / Azarisman, Shah M

    Journal of evaluation in clinical practice

    2018  Volume 24, Issue 3, Page(s) 521–527

    Abstract: Rationale: Previous research reported underutilization of statin therapy among patients with type 2 diabetes mellitus. Improving health care providers' awareness and understanding of the benefits and risks of statin treatment could be of assistance in ... ...

    Abstract Rationale: Previous research reported underutilization of statin therapy among patients with type 2 diabetes mellitus. Improving health care providers' awareness and understanding of the benefits and risks of statin treatment could be of assistance in optimizing the statin prescribing process.
    Aims and objectives: This study aimed to assess health care providers' knowledge related to statin therapy and the impact of educational outreach intervention based on the perceived knowledge.
    Methods: This was a cross-sectional study based on educational outreach intervention targeting physicians and pharmacists in 1 major tertiary hospital in the state of Pahang, Malaysia. Participants responded to a 12-item, validated questionnaire both prior to and after the outreach educational program. Two sessions were conducted separately for 2 cohorts of pharmacists and physicians. The knowledge scores prior to and after the educational intervention were calculated and compared using a paired-samples t-test.
    Results: The response rate to both pre-and post-educational outreach questionnaires was 91% (40/44). Prior to the intervention, around 84% (n37) of the participants decided to initiate statin therapy for both pre-assessment clinical case scenarios; however, only 27% (n12) could state the clinical benefits of statin therapy. Forty-five percent (n20) could state the drug to drug interactions, and 52.3% (n23) could identify the statin therapy that can be given at any time day/evening. The educational outreach program increased participants' knowledge scores of 1.450 (95% CI, 0.918 to 1.982) point, P < .0005, which is statistically significant. Forty respondents (91%) were of the opinion that statin side effects are the most common cause of treatment discontinuation.
    Conclusion: This work demonstrated the impact of an educational outreach intervention on improving health care providers' knowledge and beliefs about statin therapy. This type of intervention is considered effective for short-term knowledge enhancement. Further research is needed to test the long-term efficacy of such intervention.
    MeSH term(s) Cross-Sectional Studies ; Diabetes Mellitus, Type 2/drug therapy ; Female ; Health Knowledge, Attitudes, Practice ; Health Personnel/education ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Malaysia ; Male ; Program Evaluation ; Surveys and Questionnaires
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2018-03-06
    Publishing country England
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1327355-3
    ISSN 1365-2753 ; 1356-1294
    ISSN (online) 1365-2753
    ISSN 1356-1294
    DOI 10.1111/jep.12903
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    Zs.A 4464: Show issues Location:
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  3. Article: Statin Therapy Prescribing for Patients with Type 2 Diabetes Mellitus: A Review of Current Evidence and Challenges.

    Elnaem, Mohamed Hassan / Mohamed, Mohamad Haniki Nik / Huri, Hasniza Zaman / Azarisman, Shah M / Elkalmi, Ramadan Mohamed

    Journal of pharmacy & bioallied sciences

    2017  Volume 9, Issue 2, Page(s) 80–87

    Abstract: Use of statin therapy in patients with type 2 diabetes mellitus (T2DM) has been recommended by most clinical guidelines. Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among T2DM patients. It has been proved that statins are ... ...

    Abstract Use of statin therapy in patients with type 2 diabetes mellitus (T2DM) has been recommended by most clinical guidelines. Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among T2DM patients. It has been proved that statins are effective for primary or secondary CVD prophylaxis. Reports have highlighted the underutilization of statins in clinical practice and the suboptimal adherence to guideline recommendations. This review article points to summarize the current evidence confirming the role of statins in T2DM patients and to provide an overview of factors that may affect statins' prescribing patterns and compliance in clinical practice. Initiatives to enhance statin therapy prescribing should recognize the comprehensive nature of the prescribing process. Attempts to assure proper statin prescribing and utilization can help in achieving better clinical outcomes of statin therapy.
    Language English
    Publishing date 2017-06-30
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.JPBS_30_17
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  4. Article: Role of cardiovascular magnetic resonance in assessment of acute coronary syndrome.

    Azarisman, Shah M / Teo, Karen S / Worthley, Matthew I / Worthley, Stephen G

    World journal of cardiology

    2014  Volume 6, Issue 6, Page(s) 405–414

    Abstract: Cardiovascular disease (CVD) is the leading cause of death in the western world and is becoming more important in the developing world. Recently, advances in monitoring, revascularisation and pharmacotherapy have resulted in a reduction in mortality. ... ...

    Abstract Cardiovascular disease (CVD) is the leading cause of death in the western world and is becoming more important in the developing world. Recently, advances in monitoring, revascularisation and pharmacotherapy have resulted in a reduction in mortality. However, although mortality rates have declined, the burden of disease remains large resulting in high direct and indirect healthcare costs related to CVDs. In Australia, acute coronary syndrome (ACS) accounts for more than 300000 years of life lost due to premature death and a total cost exceeding eight billion dollars annually. It is also the main contributor towards the discrepancy in life expectancy between indigenous and non-indigenous Australians. The high prevalence of CVD along with its associated cost urgently requires a reliable but non-invasive and cost-effective imaging modality. The imaging modality of choice should be able to accelerate the diagnosis of ACS, aid in the risk stratification of de novo coronary artery disease and avail incremental information of prognostic value such as viability which cardiovascular magnetic resonance (CMR) allows. Despite its manifold benefits, there are limitations to its wider use in routine clinical assessment and more studies are required into assessing its cost-effectiveness. It is hoped that with greater development in the technology and imaging protocols, CMR could be made less cumbersome, its imaging protocols less lengthy, the technology more inexpensive and easily applied in routine clinical practice.
    Language English
    Publishing date 2014-05-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573665-6
    ISSN 1949-8462
    ISSN 1949-8462
    DOI 10.4330/wjc.v6.i6.405
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  5. Article ; Online: Characterisation of Myocardial Injury via T1 Mapping in Early Reperfused Myocardial Infarction and its Relationship with Global and Regional Diastolic Dysfunction.

    Azarisman, Shah M / Carbone, Angelo / Shirazi, Mitra / Bradley, Julie / Teo, Karen S / Worthley, Matthew I / Worthley, Stephen G

    Heart, lung & circulation

    2016  Volume 25, Issue 11, Page(s) 1094–1106

    Abstract: Background: Cardiovascular magnetic resonance (CMR) advances in imaging techniques, permits the ability to accurately characterise tissue injury post myocardial infarction. Pre-contrast T1 mapping enables this through measurement of pre-contrast T1 ... ...

    Abstract Background: Cardiovascular magnetic resonance (CMR) advances in imaging techniques, permits the ability to accurately characterise tissue injury post myocardial infarction. Pre-contrast T1 mapping enables this through measurement of pre-contrast T1 relaxation times. We investigate the relationship between T1 characterisation of myocardial injury with global and regional diastolic function.
    Methods: Revascularised acute myocardial infarction patients with normal left ventricular (LV) systolic function on TTE were assessed by 1.5T CMR. Acute regional diastolic wall motion abnormalities, global diastolic function measurements, acute segmental damage fraction with LGE and mean segmental pre-contrast T1 values were assessed on matching short axis slices.
    Results: Forty-four patients were analysed. Mean LVEF was 62.1±9.4%. No difference between NSTEMI (22/44) and STEMI in mean pre-contrast T1 values of infarcted (1025.0±109.2 vs 1011.0±81.6ms, p=0.70), adjacent (948.3±45.3 vs 941.1±46.6ms, p=0.70) and remote (888.8±52.8 vs 881.2±54.5ms, p=0.66) segments was detected. There was no correlation between pre-contrast T1 of infarcted segments with global diastolic dysfunction (E/A, r
    Conclusion: Cardiac magnetic resonance evaluation of pre-contrast T1 values revealed no difference between NSTEMI and STEMI patients in terms of tissue characterisation post-myocardial infarction. However, pre-contrast T1 of infarcted tissue is significantly correlated with regional diastolic circumferential strain rate.
    MeSH term(s) Adult ; Aged ; Diastole ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myocardial Infarction/complications ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/physiopathology ; Myocardial Infarction/therapy ; Myocardium ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/etiology ; Ventricular Dysfunction, Left/physiopathology
    Language English
    Publishing date 2016-11
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2016.03.011
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4988: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: Magnetic resonance imaging in the diagnosis and surveillance of thoracic aortic perigraft seroma and its complications.

    Chua, Seng Keong / Azarisman, Shah M / Glenie, Timothy / Baillie, Timothy / Teo, Karen S / Worthley, Stephen Grant

    Vascular and endovascular surgery

    2012  Volume 46, Issue 8, Page(s) 691–692

    MeSH term(s) Aorta, Thoracic/pathology ; Aorta, Thoracic/surgery ; Aortic Aneurysm, Thoracic/pathology ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis Implantation/adverse effects ; Humans ; Magnetic Resonance Imaging ; Male ; Predictive Value of Tests ; Seroma/diagnosis ; Seroma/etiology ; Seroma/pathology ; Subclavian Artery/pathology ; Subclavian Artery/surgery
    Language English
    Publishing date 2012-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2076272-0
    ISSN 1938-9116 ; 1538-5744
    ISSN (online) 1938-9116
    ISSN 1538-5744
    DOI 10.1177/1538574412460103
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    Zs.A 622: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Myocardial infarction induced by appetite suppressants in Malaysia.

    Azarisman, Shah M / Magdi, Yahya A / Noorfaizan, Saidin / Oteh, Maskon

    The New England journal of medicine

    2007  Volume 357, Issue 18, Page(s) 1873–1874

    MeSH term(s) Adult ; Appetite Depressants/adverse effects ; Cyclobutanes/adverse effects ; Electrocardiography ; Female ; Humans ; Malaysia ; Myocardial Infarction/chemically induced ; Phentermine/adverse effects
    Chemical Substances Appetite Depressants ; Cyclobutanes ; Phentermine (C045TQL4WP) ; sibutramine (WV5EC51866)
    Language English
    Publishing date 2007-11-01
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc070990
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  8. Article ; Online: An ideal image: effusive constrictive pericarditis.

    Azarisman, Shah M / Richardson, James D / Chua, S K / Cunningham, Michael S / Teo, Karen S / Worthley, Stephen G

    The American journal of medicine

    2013  Volume 126, Issue 1, Page(s) 25–26

    MeSH term(s) Adult ; Candida albicans/isolation & purification ; Candidiasis, Invasive/complications ; Humans ; Magnetic Resonance Imaging ; Male ; Pericarditis, Constrictive/diagnosis ; Pericarditis, Constrictive/microbiology
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2012.08.014
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  9. Article ; Online: Tissue injury characterization by pre-contrast T1 mapping post myocardial infarction

    Azarisman Shah M / Li Andrew / Wong Dennis T / Richardson James D / Chua Seng / Samaraie Luay / Sidharta Samuel L / Glenie Timothy / Williams Kerry / Koschade Ben / Teo Karen / Worthley Matthew / Worthley Stephen G

    Journal of Cardiovascular Magnetic Resonance, Vol 15, Iss Suppl 1, p E

    2013  Volume 33

    Keywords Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Optimal planimetry location for MRI-derived mitral inflow velocity assessment of diastolic function

    Azarisman Shah M / Li Andrew / Richardson James D / Wong Dennis T / Chua Seng / Cursaro Michael / Schirripa Vince / Williams Kerry / Koschade Ben / Shirazi Mitra / Bradley Julie / Teo Karen / Worthley Matthew / Worthley Stephen G

    Journal of Cardiovascular Magnetic Resonance, Vol 15, Iss Suppl 1, p P

    2013  Volume 90

    Keywords Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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