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  1. Article ; Online: Microsatellite markers-aided dissection of iron, zinc and cadmium accumulation potential in

    Rasheed, Asima / Ahmad, Javed / Nadeem, Majid / Rashid, Muhammad Abdul Rehman / Azeem, Farrukh

    PeerJ

    2023  Volume 11, Page(s) e15229

    Abstract: Background: Wheat is a staple cereal food around the globe. It provides a significant source of proteins, carbohydrates, and other micronutrients to humans. When grown on cadmium (Cd) contaminated soils, the uptake of trace elements : Methods: In ... ...

    Abstract Background: Wheat is a staple cereal food around the globe. It provides a significant source of proteins, carbohydrates, and other micronutrients to humans. When grown on cadmium (Cd) contaminated soils, the uptake of trace elements
    Methods: In this study, wheat accessions were used to investigate the impact of soil application of Zn (5 mg/kg, 20 mg/kg) and Cd (0 mg/kg, 10 mg/kg) on accumulation of these elements in wheat grains. A total of 45 Fe, Zn, and Cd transporter-related genes were used to design 101 gene-specific SSR (simple sequence repeat) markers.
    Results: In response to Cd stress, application of 20 mg/Kg Zn improved Fe (64.6 ug/g) and Zn (48.3 ug/g) accumulation in wheat grains as well as agronomic traits. Marker trait association revealed that SSR markers based on
    MeSH term(s) Humans ; Zinc/metabolism ; Cadmium/metabolism ; Iron/metabolism ; Triticum/genetics ; Plant Breeding ; Edible Grain/metabolism ; Microsatellite Repeats/genetics
    Chemical Substances Zinc (J41CSQ7QDS) ; Cadmium (00BH33GNGH) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-04-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.15229
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  2. Article ; Online: Dominance of

    Zahra, Syeda Tahseen / Tariq, Mohsin / Abdullah, Muhammad / Azeem, Farrukh / Ashraf, Muhammad Arslan

    PeerJ

    2023  Volume 11, Page(s) e14621

    Abstract: Wheat ( ...

    Abstract Wheat (
    MeSH term(s) Bacillus ; Cellulases ; Phosphates ; Phylogeny ; Polygalacturonase ; Rhizosphere ; Salt Stress ; Triticum/growth & development ; Triticum/microbiology ; Zinc
    Chemical Substances Cellulases (EC 3.2.1.-) ; Phosphates ; Polygalacturonase (EC 3.2.1.15) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.14621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An integrated network pharmacology approach to discover therapeutic mechanisms of

    Tabassum, Ayesha / Nadeem, Habibullah / Azeem, Farrukh / Siddique, Muhammad Hussnain / Zubair, Muhammad / Kanwal, Aqsa / Rasul, Ijaz

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–18

    Abstract: Bell's palsy (BP) can result in facial paralysis. Inflammation or injury to the cranial nerves that regulate the facial muscles is primarily responsible for that disease. ...

    Abstract Bell's palsy (BP) can result in facial paralysis. Inflammation or injury to the cranial nerves that regulate the facial muscles is primarily responsible for that disease.
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2326196
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Precision Genome Editing with CRISPR-Cas9.

    Rahman, Shahroz / Ikram, Abdul Rehman / Azeem, Farrukh / Tahir Ul Qamar, Muhammad / Shaheen, Tayyaba / Mehboob-Ur-Rahman

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2788, Page(s) 355–372

    Abstract: The CRISPR/Cas9 system is a revolutionary technology for genome editing that allows for precise and efficient modifications of DNA sequences. The system is composed of two main components, the Cas9 enzyme and a guide RNA (gRNA). The gRNA is designed to ... ...

    Abstract The CRISPR/Cas9 system is a revolutionary technology for genome editing that allows for precise and efficient modifications of DNA sequences. The system is composed of two main components, the Cas9 enzyme and a guide RNA (gRNA). The gRNA is designed to specifically target a desired DNA sequence, while the Cas9 enzyme acts as molecular scissors to cut the DNA at that specific location. The cell then repairs the digested DNA, either through nonhomologous end joining (NHEJ) or homology-directed repair (HDR), resulting in either indels or precise modifications of DNA sequences with broad implications in biotechnology, agriculture, and medicine. This chapter provides a practical approach for utilizing CRISPR/Cas9 in precise genome editing, including identifying the target gene sequence, designing gRNA and protein (Cas9), and delivering the CRISPR components to target cells.
    MeSH term(s) CRISPR-Cas Systems ; Gene Editing/methods ; RNA, Guide, CRISPR-Cas Systems/genetics ; Humans ; DNA End-Joining Repair ; CRISPR-Associated Protein 9/metabolism ; CRISPR-Associated Protein 9/genetics
    Chemical Substances RNA, Guide, CRISPR-Cas Systems ; CRISPR-Associated Protein 9 (EC 3.1.-)
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3782-1_21
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  5. Article ; Online: Bioplastics from waste biomass of marine and poultry industries

    Arif, Amna / Azeem, Farrukh / Rasul, Ijaz / Siddique, Muhammad Hussnain / Zubair, Muhammad / Muneer, Faizan / Zaheer, Warda / Nadeem, Habibullah

    J Biosci. 2023 June, v. 48, no. 2 p.11-11

    2023  

    Abstract: Plastics are indispensable and typically derived from non-renewable sources. The extensive production and indiscriminate use of synthetic plastics pose a serious threat to the environment and lead to problems due to their non-biodegradability. Various ... ...

    Abstract Plastics are indispensable and typically derived from non-renewable sources. The extensive production and indiscriminate use of synthetic plastics pose a serious threat to the environment and lead to problems due to their non-biodegradability. Various forms of plastics that are used in daily life should be limited and replaced by biodegradable materials. To deal with the challenges of sustainability or environmental issues that occur due to the production and disposal of synthetic plastics, biodegradable and environment-friendly plastics are crucial. Utilizing renewable sources such as keratin derived from chicken feathers and chitosan from shrimp cell wastes as an alternative to obtain safe bio-based polymers has gained much attention because of rising environmental issues. Approximately, 2–5 billion tons of waste are produced by the poultry and marine industries each year, adversely impacting the environment. These polymers are more acceptable and eco-friendly compared with conventional plastics due to their biostability, biodegradability, and excellent mechanical properties. The replacement of synthetic plastic packaging with biodegradable polymers from animal by-products significantly reduces the volume of waste generated. This review highlights important aspects such as the classification of bioplastics, properties and use of waste biomass for bioplastics production, their structure, mechanical properties, and demand in industrial sectors such as agriculture, biomedicine, and food packaging.
    Keywords biodegradability ; biomass ; bioplastics ; chickens ; chitosan ; keratin ; medicine ; shrimp ; wastes
    Language English
    Dates of publication 2023-06
    Size p. 11.
    Publishing place Springer India
    Document type Article ; Online
    Note Review
    ZDB-ID 756157-x
    ISSN 0973-7138 ; 0250-5991
    ISSN (online) 0973-7138
    ISSN 0250-5991
    DOI 10.1007/s12038-023-00332-8
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    In stock of ZB MED Bonn / Germany

    Z 5290: Show issues

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  6. Article: A genome-wide comparative analysis of bZIP transcription factors in

    Azeem, Farrukh / Tahir, Hira / Ijaz, Usman / Shaheen, Tayyaba

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2020  Volume 26, Issue 3, Page(s) 433–444

    Abstract: Basic leucine zipper motif (bZIP) transcription factors (TFs) are involved in plant growth regulation, development, and environmental stress responses. These genes have been well characterized in model plants. In current study, a genome-wide analysis ... ...

    Abstract Basic leucine zipper motif (bZIP) transcription factors (TFs) are involved in plant growth regulation, development, and environmental stress responses. These genes have been well characterized in model plants. In current study, a genome-wide analysis of
    Language English
    Publishing date 2020-02-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-020-00771-9
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  7. Article: A genome-wide comparative analysis of bZIP transcription factors in G. arboreum and G. raimondii (Diploid ancestors of present-day cotton)

    Azeem, Farrukh / Tahir, Hira / Ijaz, Usman / Shaheen, Tayyaba

    Physiology and molecular biology of plants. 2020 Mar., v. 26, no. 3

    2020  

    Abstract: Basic leucine zipper motif (bZIP) transcription factors (TFs) are involved in plant growth regulation, development, and environmental stress responses. These genes have been well characterized in model plants. In current study, a genome-wide analysis of ... ...

    Abstract Basic leucine zipper motif (bZIP) transcription factors (TFs) are involved in plant growth regulation, development, and environmental stress responses. These genes have been well characterized in model plants. In current study, a genome-wide analysis of bZIP genes was performed in Gossypium raimondii and Gossypium arboreum taking Arabidopsis thaliana as a reference genome. In total, 85 members of G. raimondii and 87 members of G. arboreum were identified and designated as GrbZIPs and GabZIPs respectively. Phylogenetic analysis clustered bZIP genes into 11 subgroups (A, B, C, D, F, G, H, I, S and X). Gene structure analysis to find the intro-exon structures revealed 1–14 exons in both species. The maximum number of introns were present in subgroup G and D while genes in subgroup S were intron-less except GrbZIP78, which is a unique characteristic as compared to other groups. Results of motif analysis predicted that all three species share a common bZIP motif. A detailed comparison of bZIPs gene distribution on chromosomes has shown a diverse arrangement of genes in both cotton species. Moreover, the functional similarity with orthologs was also predicted. The findings of this study revealed close similarity in gene structure of both cotton species and diversity in gene distribution on chromosomes. This study supports the divergence of both species from the common ancestor and later diversity in gene distribution on chromosomes due to evolutionary changes. Additionally, this work will facilitate the functional characterization of bZIP genes in cotton. Outcomes of this study represent foundation research on the bZIP TFs family in cotton and as a reference for other crops.
    Keywords Arabidopsis thaliana ; Gossypium arboreum ; Gossypium raimondii ; ancestry ; basic-leucine zipper transcription factors ; chromosomes ; cotton ; diploidy ; exons ; genome-wide association study ; introns ; leucine zipper ; models ; phylogeny ; plant growth ; stress response
    Language English
    Dates of publication 2020-03
    Size p. 433-444.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-020-00771-9
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  8. Article: Integrated omics and machine learning-assisted profiling of cysteine-rich-receptor-like kinases from three peanut spp

    Fatima, Kinza / Sadaqat, Muhammad / Azeem, Farrukh / Rao, Muhammad Junaid / Albekairi, Norah A / Alshammari, Abdulrahman / Tahir Ul Qamar, Muhammad

    Frontiers in genetics

    2023  Volume 14, Page(s) 1252020

    Abstract: ... Arachis ... ...

    Abstract Arachis hypogaea
    Language English
    Publishing date 2023-09-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1252020
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  9. Article: Computational analysis and expression profiling of potassium transport-related gene families in mango (

    Tan, Lin / Waqas, Muhammad / Rehman, Abdul / Rashid, Muhammad Abdul Rehman / Fiaz, Sajid / Manzoor, Hamid / Azeem, Farrukh

    Frontiers in plant science

    2023  Volume 13, Page(s) 1102201

    Abstract: Mango ( ...

    Abstract Mango (
    Language English
    Publishing date 2023-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.1102201
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  10. Article: Effect of foliar applied zinc sulphate on phenotypic variability, association and heritability of yield and zinc biofortification related traits of wheat genotypes.

    Azeem, Asad / Ul-Allah, Sami / Azeem, Farrukh / Naeem, Muhammad / Sattar, Abdul / Ijaz, Muhammad / Sher, Ahmad

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19643

    Abstract: Wheat is an important food crop worldwide, providing substantial calories and nourishment. Genetic variability in wheat germplasm is crucial for the development of cultivars with desirable features. This two years study (2020-21 and 2021-22) was ... ...

    Abstract Wheat is an important food crop worldwide, providing substantial calories and nourishment. Genetic variability in wheat germplasm is crucial for the development of cultivars with desirable features. This two years study (2020-21 and 2021-22) was conducted to evaluate 13 diverse wheat genotypes factorially combined with foliar-applied zinc sulphate (0, 0.4, 0.6%) arranged in a triplicate randomized complete block design. Boxplot analysis revealed the significant (
    Language English
    Publishing date 2023-09-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19643
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