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  1. Book ; Online ; Thesis: Ideologies, Ideological Asymmetries, and the Psychological Roots of Political Behavior

    Azevedo, Flavio [Verfasser] / Kaiser, André [Gutachter]

    2023  

    Author's details Flavio Azevedo ; Gutachter: André Kaiser
    Keywords Psychologie ; Psychology
    Subject code sg150
    Language English
    Publisher Universitäts- und Stadtbibliothek Köln
    Publishing place Köln
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Article: Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA

    Pereira, Humberto / Azevedo, Flávio / Domingues, Lucília / Johansson, Björn

    Computational and Structural Biotechnology Journal. 2022, v. 20

    2022  

    Abstract: Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids, ... ...

    Abstract Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids, polyketides, and fatty acids. The yeast Saccharomyces cerevisiae remains one of the preferred cell factories, but has a limited capacity to produce malonyl-CoA compared to oleaginous organisms. We developed a new S. cerevisiae strain with a conditional allele of ACC1, the essential acetyl-CoA carboxylase (ACC) gene, as a tool to test heterologous genes for complementation. Yarrowia lipolytica is an oleaginous yeast with a higher capacity for lipid production than S. cerevisiae, possibly due to a higher capacity to produce malonyl-CoA. Measuring relative intracellular malonyl-CoA levels with an in-vivo biosensor confirmed that expression of Y. lipolytica ACC in S. cerevisiae leads to a higher accumulation of malonyl-CoA compared with overexpression of the native gene from an otherwise identical vector. The higher accumulation was generally accompanied by a decreased growth rate. Concomitant expression of both the homologous and heterologous ACC1 genes eliminated the growth defect, with a marginal reduction of malonyl-CoA accumulation.
    Keywords Saccharomyces cerevisiae ; Yarrowia lipolytica ; acetyl coenzyme A ; acetyl-CoA carboxylase ; alleles ; biosensors ; biotechnology ; carboxylation ; flavonoids ; malonyl coenzyme A ; polyketides ; yeasts
    Language English
    Size p. 779-787.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2022.01.020
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA.

    Pereira, Humberto / Azevedo, Flávio / Domingues, Lucília / Johansson, Björn

    Computational and structural biotechnology journal

    2022  Volume 20, Page(s) 779–787

    Abstract: Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids, ... ...

    Abstract Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids, polyketides, and fatty acids. The yeast
    Language English
    Publishing date 2022-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2022.01.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mapping political trust and involvement in the personality space-A meta-analysis and new evidence.

    Bromme, Laurits / Rothmund, Tobias / Azevedo, Flávio

    Journal of personality

    2022  Volume 90, Issue 6, Page(s) 846–872

    Abstract: Objective: Relations between the Big Five personality dispositions and individual differences in political trust and involvement in politics have been investigated in many studies. We aimed to systematically integrate these findings and further explore ... ...

    Abstract Objective: Relations between the Big Five personality dispositions and individual differences in political trust and involvement in politics have been investigated in many studies. We aimed to systematically integrate these findings and further explore the correlations at different hierarchical levels of the Big Five and political trust and involvement.
    Method: We conducted a meta-analysis of 43 publications (N
    Results: The meta-analysis revealed substantial correlations between involvement and openness (+), extraversion (+), and neuroticism (-), but only small correlations between trust and the Big Five. We also found a substantial amount of inconsistency in findings across studies. Our additional analyses showed that (a) correlations with the Big Five were larger for higher-order factors of general political trust (as opposed to subdimensions such as trust in politicians) and general political involvement (as opposed to subdimensions such as political interest) and (b) correlational patterns within each Big Five domain differed across facets.
    Conclusion: Our analyses indicate that political involvement is more strongly linked to the Big Five than political trust. We discuss the theoretical and empirical relevance of hierarchical constructs.
    MeSH term(s) Humans ; Trust ; Personality ; Extraversion, Psychological ; Neuroticism ; Personality Inventory
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 420745-2
    ISSN 1467-6494 ; 0022-3506
    ISSN (online) 1467-6494
    ISSN 0022-3506
    DOI 10.1111/jopy.12700
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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article ; Online: Climate of conspiracy: A meta-analysis of the consequences of belief in conspiracy theories about climate change.

    Biddlestone, Mikey / Azevedo, Flavio / van der Linden, Sander

    Current opinion in psychology

    2022  Volume 46, Page(s) 101390

    Abstract: Despite widespread scientific consensus on climate change, conspiracy theories about its causes and consequences are flourishing. In response, psychological research has started to investigate the consequences of espousing conspiracy beliefs about ... ...

    Abstract Despite widespread scientific consensus on climate change, conspiracy theories about its causes and consequences are flourishing. In response, psychological research has started to investigate the consequences of espousing conspiracy beliefs about climate change. Although some scholars maintain that the evidence for a causal link between belief in conspiracy theories and behavior remains elusive, others have argued that climate change conspiracy theories undermine pro-climate action. To shed further light on this question across a range of outcome measures, we present a meta-analysis of 22 independent samples (N
    MeSH term(s) Climate Change ; Humans ; Intention ; Trust/psychology
    Language English
    Publishing date 2022-06-11
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2831565-0
    ISSN 2352-2518 ; 2352-250X ; 2352-250X
    ISSN (online) 2352-2518 ; 2352-250X
    ISSN 2352-250X
    DOI 10.1016/j.copsyc.2022.101390
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  6. Article ; Online: Psychological underpinnings of pandemic denial - patterns of disagreement with scientific experts in the German public during the COVID-19 pandemic.

    Rothmund, Tobias / Farkhari, Fahima / Ziemer, Carolin-Theresa / Azevedo, Flávio

    Public understanding of science (Bristol, England)

    2022  Volume 31, Issue 4, Page(s) 437–457

    Abstract: We investigated pandemic denial in the general public in Germany after the first wave of COVID-19 in May 2020. Using latent class analysis, we compared patterns of disagreement with claims about (a) the origin, spread, or infectiousness of the SARS-CoV-2 ...

    Abstract We investigated pandemic denial in the general public in Germany after the first wave of COVID-19 in May 2020. Using latent class analysis, we compared patterns of disagreement with claims about (a) the origin, spread, or infectiousness of the SARS-CoV-2 virus and (b) the personal risk from COVID-19 between scientific laypersons (
    MeSH term(s) COVID-19/epidemiology ; Dissent and Disputes ; Humans ; Pandemics ; SARS-CoV-2 ; Social Media
    Language English
    Publishing date 2022-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421272-9
    ISSN 1361-6609 ; 0963-6625
    ISSN (online) 1361-6609
    ISSN 0963-6625
    DOI 10.1177/09636625211068131
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  7. Article ; Online: 'Big team' science challenges us to reconsider authorship.

    Coles, Nicholas A / DeBruine, Lisa M / Azevedo, Flavio / Baumgartner, Heidi A / Frank, Michael C

    Nature human behaviour

    2023  Volume 7, Issue 5, Page(s) 665–667

    MeSH term(s) Humans ; Authorship ; Publishing
    Language English
    Publishing date 2023-03-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2397-3374
    ISSN (online) 2397-3374
    DOI 10.1038/s41562-023-01572-2
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  8. Article: Technical Report: Percutaneous Reductions on Gartland Type III Supracondylar Fractures.

    Gonçalves, Rafaela M / Lobo, Mariana O / Azevedo, Flávio E / Braga, Felipe M / Freitas, Anderson

    Cureus

    2022  Volume 14, Issue 6, Page(s) e26202

    Abstract: Various surgical treatments for supracondylar fracture in children remain the motive of research and study. A common factor in each technique is anatomic reduction, which is critical for the excellent recovery of the fracture. Anatomic reduction is ... ...

    Abstract Various surgical treatments for supracondylar fracture in children remain the motive of research and study. A common factor in each technique is anatomic reduction, which is critical for the excellent recovery of the fracture. Anatomic reduction is preferably realized through closed and percutaneous approaches. This study aimed to present a closed percutaneous technique to treat Gartland III supracondylar fractures to aggregate a facilitating factor in the surgical approach to this condition. Our technique was applied to surgical patients in orthopedic and traumatology emergency care and illustrated by a synthetic elbow model, including soft tissue and intraoperative images.
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.26202
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  9. Article ; Online: Optimization of a hybrid bacterial/

    Pozdniakova, Tatiana A / Cruz, João P / Silva, Paulo César / Azevedo, Flávio / Parpot, Pier / Domingues, Maria Rosario / Carlquist, Magnus / Johansson, Björn

    Metabolic engineering communications

    2023  Volume 17, Page(s) e00224

    Abstract: Fatty acids are produced by eukaryotes like baker's ... ...

    Abstract Fatty acids are produced by eukaryotes like baker's yeast
    Language English
    Publishing date 2023-06-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2821894-2
    ISSN 2214-0301 ; 2214-0301
    ISSN (online) 2214-0301
    ISSN 2214-0301
    DOI 10.1016/j.mec.2023.e00224
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  10. Article ; Online: Towards a culture of open scholarship: the role of pedagogical communities.

    Azevedo, Flávio / Liu, Meng / Pennington, Charlotte R / Pownall, Madeleine / Evans, Thomas Rhys / Parsons, Sam / Elsherif, Mahmoud Medhat / Micheli, Leticia / Westwood, Samuel J

    BMC research notes

    2022  Volume 15, Issue 1, Page(s) 75

    Abstract: The UK House of Commons Science and Technology Committee has called for evidence on the roles that different stakeholders play in reproducibility and research integrity. Of central priority are proposals for improving research integrity and quality, as ... ...

    Abstract The UK House of Commons Science and Technology Committee has called for evidence on the roles that different stakeholders play in reproducibility and research integrity. Of central priority are proposals for improving research integrity and quality, as well as guidance and support for researchers. In response to this, we argue that there is one important component of research integrity that is often absent from discussion: the pedagogical consequences of how we teach, mentor, and supervise students through open scholarship. We justify the need to integrate open scholarship principles into research training within higher education and argue that pedagogical communities play a key role in fostering an inclusive culture of open scholarship. We illustrate these benefits by presenting the Framework for Open and Reproducible Research Training (FORRT), an international grassroots community whose goal is to provide support, resources, visibility, and advocacy for the adoption of principled, open teaching and mentoring practices, whilst generating conversations about the ethics and social impact of higher-education pedagogy. Representing a diverse group of early-career researchers and students across specialisms, we advocate for greater recognition of and support for pedagogical communities, and encourage all research stakeholders to engage with these communities to enable long-term, sustainable change.
    MeSH term(s) Fellowships and Scholarships ; Humans ; Mentors ; Reproducibility of Results ; Research Personnel ; Students
    Language English
    Publishing date 2022-02-22
    Publishing country England
    Document type Letter
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-022-05944-1
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